Sequence alignment for CL0400

PF10439

C6SS71_STRMN/1-72M.N----TQ..-.AFEQFNVMDNEALSTVEG.....G.........GMIRCALGTAGSAGLGFVGGMGAGTVTLPV....
A3FKG3_9LACO/1-67M..----....-......KVLNECQLQTVVG.....G......KNWSVAKCGGTIGTNIAIGAWRGARAGSFFGQP....
I6T932_STRMG/1-59M..----...E-KQYNNFKILNTDALENIQG.....G........GRAPRCAALVGASIYDGLAV...............
C2HL33_LACAI/1-70M..----....-...EKLMVLNEEKLSYVIG.....G......GNPKVAHCASQIGRSTAWGAVSGAATGTAVGQA....
Q73F42_BACC1/1-68M..----....-....NLETLTEKELLEISA.....G.........GAGKCVAGIASGAALGFLNGASYTWEFGPAVI..
A0A021PZ53_STAAU/1-68M..----....-......KKLETKELVSING.....G......KKNTWQQNVSGAIGSTVAGAGLGGAICGP........
G6CHE2_LACCU/1-59M..----....-...KNVQSLSKEELVLVVG.....G........YTAKQCLQAIGSWGIAGTGAGA.............
O85756_9LIST/1-67M..----....-...HKVKKLNNQELQQIVG.....G........YSSKDCLKDIGKGIGAGTVAGAAGGGLAAG.....
O54454_STRTR/1-72M..----..NT-ITICKFDVLDAELLSTVEG.....G........YSGKDCLKDMGGYALAGAGSGALWGAPAGG.....
B1RZ28_STREE/1-84M..----..DT-KIMEQFHEMDITMLSSIEG.....G.......KNNWQTNVLEGGGAAFGGWGLGTAICAASGVGAPFM
Q03J31_STRTD/1-71M.A----TQ..-.TIENFNTLDLETLASVEGGGCSWG...........GFAKQGVATGVGNGLRLGIKTRTW........
F0TH56_LACA3/1-73M..----....-...SKAEVLNEEELTDVVG.....G...THGHNGKVAKCGGYILRGAGTGALTGALTGTAAGAA....
E1JNH1_9LACO/1-60M..----....-..MKEFTVLTECELAKVDG.....G........KRGPNCVGNFLGGLFAGAAAGVPLG..........
M2KRF4_STRMG/1-75M.N----TQ..-.AFEQFNVMDNEALSAVEG.....G........GRGWNCAAGIALGAGQGYMATAGGTAFLGPYAI..
Q03D40_LACC3/1-67M..----....-...SKTRKLSELELQQFVG.....G........SDSNKCLMGLVGGWAIGGLNGAGSLSGFGP.....
O54455_STRTR/1-64M..----....-KQYNGFEVLHELDLANVTG.....G...........QINWGSVVGHCIGGAIIGGAFSGG........
F4AFZ5_LACJH/1-59M..----....-.......KLNDKELSKIVG.....G........NRWGDTVLSAASGAGTGIKACKSFGP.........
A0A034X142_STREE/1-63M..----....-...NTYCNINETMLSEVYG.....G........NSGGAAVVAALGCAAGGVKYGKILGP.........
A0A029SMY7_STRPY/1-69M..----....-..IKFAEEIQKEELFHIIG.....G........YSATDCKNHLIGGITSGAIAGGVGAGMATLG....
I6U088_STRMG/1-67M.D----TQ..-.AFEQFDVMDSQTLSTVEG.....G.............KVSGGEAVAAIGICATASAA..........
Q8DSB5_STRMU/1-79MMN----TR..-.TLEQFDAMDVDMLAAVEG.....G.........NWGQCIVGTGSSALAGGLAGAGTGAAVSAPAAEG
LAFA_LACJO/1-70M..----....-...KQFNYLSHKDLAVVVG.....G.......RNNWQTNVGGAVGSAMIGATVGGTICGP........
A5LX13_STREE/1-73M..----..NT-KMLSQLEVMDTEMLAKVEG.....G........YSSTDCQNALITGVTTGIITGGTGAGLATLG....
A5MYA6_STREE/1-54M.N----TK..-.MMSQFSVMDNEMLDRIEG.....G.................IFGVDDALFWAG..............
Q2MDB2_BACCE/1-70M..----....-...ENLQMLTEEELMEIEG.....G.....GWWNSWGKCVAGTIGGAGTGGLGGAAAGSAVPV.....
Q9ZEU9_LACPN/1-65M..----....-.....YKELTVDELALIDG.....G....KKKKKKVACTWGNAATAAASGAVXGILGGP.........
F0TH60_LACA3/1-61M..----....-......KQLNSEQLQNIIG.....G........NRWTNAYSAALGCAVPGVKYGKKLGGV........
O85757_9LIST/1-56M..----....-....KKELLNKNEMSRIIG.....G...........KINWGNVGGSCVGGAVIGGA............
Q5LYA7_STRT1/1-74M.A----TQ..-.TIENFNTLDLETLASVEG.....G...........GCSWRGAGGATVQGAIGGAFGGNVVLPVVGSV
I6U3Y5_STRMG/1-63M.N----TH..-.VLEQFDVMDSQVPSAIEG.....G...........GCSWKGADKAGFSGGVGGLIGA..........
Q035H7_LACC3/1-68M..----....-..SYNYRQIDDFQLSGVSG.....G....KKKFDCAATFVTGITAGIGSGTITGLAGGP.........
F0TH58_LACA3/1-68M..----....-...SRVEVLNEEELSAVVG.....GTGGKRARQRKISNCVNYIRMGASSVGGAGAV............
F0TH61_LACA3/1-75M..----....-...SKGEVLNEDELTAVVG.....G..SKGKGRNNWAGNTIGIVSSAATGAALGSAICGP........
Q9XDR7_9LACO/1-70M..----....-...KNFNTLSFETLANIVG.....G.......RNNWAANIGGVGGATVAGWALGNAVCGP........
Q1J813_STRPF/1-76MMN----TK..-.TMEQFEVMNSEMLAGVEG.....G.......WGGWGEAIAGLLGGFAPSPTLDQLNGKWPIRKPSK.

PF03047

A8B010_STRGC/1-38MKKKNKQNLLP-KELQQFEILTERKLEQVTG-----G-------------------------------------------
Q8DSB2_STRMU/1-30MNT........-QKLNQFETMDTETLATIEG-----G-------------------------------------------
I6L8Z2_STRMU/1-32MKK......TL-SLKNDFKEIKTDELEIIIG-----G-------------------------------------------
CSP1_STRR6/1-31MKN.......T-VKLEQFVALKEKDLQKIKG-----G-------------------------------------------
Q5M2V9_STRT2/1-30MAN........-NTINNFETLDNHALEQVVG-----G-------------------------------------------
Q7CRB4_STRR6/1-30MDK.......K-QNLTSFQELTTTELNQITG-----G-------------------------------------------

PF04604

A0A029S6Z0_STRPY/1-48MKNSKD......ILTNAIEEVSEKELMEVAG-----G-------------------KK.GSGWFATITD-----------
A0FL76_9ENTE/1-51MMNAT.......ENQIFVETVSDQELEMLIG-----G-------------------A..GRGWIKTLTK-----------
G2GW18_STRSL/1-56MKSTNNQSIAEIAAVNSLQEVSMEELDQIIG-----A-------------------...GNGVVLTLTH-----------
LANB_STRP9/1-50MTKEH.......EIINSIQEVSLEELDQIIG-----A-------------------G..KNGVFKTISH-----------
A0SXQ1_STRMG/1-50MKQSN.......EMLELIQEVSLDELDQVIG-----G-------------------M..GKGAVGTISH-----------
O85355_BUTFI/1-47MNK.........ELNALTNPIDEKELEQILG-----G-------------------...GNGVIKTISH-----------
A0SXQ2_STRMG/1-53MKKGTQLYL...EALEALQEIKVEELDTFIG-----G-------------------...GGRASNTISS-----------
LANA_STRMG/1-53MNKLNS......NAVVSLNEVSDSELDTILG-----G-------------------NRWWQGVVPTVSY-----------
LANA_RUMGN/1-47MRN.........DVLTLTNPMEEKELEQILG-----G-------------------...GNGVLKTISH-----------
P71449_9LACT/1-50MKEQ........NSFNLLQEVTESELDLILG-----A-------------------KG.GSGVIHTISH-----------
A6MER2_STRMC/1-53MKNNNKICQ...DALESLQELKLEEVDELLG-----G-------------------...AGHGVNTISA-----------
Q50848_KOCVA/1-46MT..........NAFQALDEVTDAELDAILG-----G-------------------...GSGVIPTISH-----------
LANNA_STASI/1-56MENSKVMKDI..EVANLLEEVQEDELNEVLG-----A-------------------KK.KSGVIPTVSH-----------
O31051_STRPY/1-51MEEKMCL.....GALNALQEFQIEELDNLLG-----G-------------------...RGHGVNTISA-----------
Q09II3_STRSL/1-55MAKQQMNLVEI.EAMNSLQELTLEELDNVLG-----A-------------------...GGGVIQTISH-----------

PF04369

K7WBI6_LACLC/1-60M-----------KNQLNFNIVSDEELSEANG-----G-------------KLTFIQSTAAGDLYYNTNTHKY--------
Q7X5J4_LEUME/1-53M-----------QDKTNFKILSDSELSTISG-----G-------------.......KGVLGWLSMASSALT--------
K7VRC1_LACLC/1-60M-----------KNQLNFNIVSDEELAEVNG-----G-------------SLQYVMSAGPYTWYKDTRTGKT--------

PF08129

Q9L9U6_ENTFL/1-57M--------------KQYKVLNEKEMKKPIG-----G-----------ESVFSKIGNAVGPAAYWILKG-----------
Q8VPA2_ENTFL/1-57M--------------KQYKVLNEKEMKKTIG-----G-----------ESVFSKIGNAVGPAAYWILKG-----------

PF10439

C6SS71_STRMN/1-72..VGTVSGA......ALGGWSGAAVGA
A3FKG3_9LACO/1-67..VSVGTGA......LIGASAGAIGGS
I6T932_STRMG/1-59..VGDPVGV........AMAAGTIAAG
C2HL33_LACAI/1-70..VGALGGA......LFGGSMGVIKGS
Q73F42_BACC1/1-68..YGGGVGA......LAGGVAGGIGSC
A0A021PZ53_STAAU/1-68..ACAVVGA.HYGPIIWAGVSGATGAF
G6CHE2_LACCU/1-59..AGGPAGA......FVGAHVGVIAGS
O85756_9LIST/1-67..LGAIPGA......FVGAHFGVIGGS
O54454_STRTR/1-72..VGALPGA......FVGAHVGAIAGG
B1RZ28_STREE/1-84G.ACGYIGA.KFGVDLWAGVTGATGGF
Q03J31_STRTD/1-71..QGAVAGA......AGGAIVGGVGYG
F0TH56_LACA3/1-73..VGAFGGA......MFGGSIGIIKGS
E1JNH1_9LACO/1-60.....PAGI......VGGANLGMVGGA
M2KRF4_STRMG/1-75..GTGAFGA......IAGGIGGALNSC
Q03D40_LACC3/1-67..AGVTIGG......LYGTLSGILTGY
O54455_STRTR/1-64..AAAGVGC......LVGSGKAIINGL
F4AFZ5_LACJH/1-59..WGMAICG......VGGAAIGGYFGY
A0A034X142_STREE/1-63..WGAAIGG......IGGAVVCGYLAY
A0A029SMY7_STRPY/1-69..VGGVAGA......FAGAHVGAIAGG
I6U088_STRMG/1-67..IGGLAGATLVTPYCVGTW.GLIRSH
Q8DSB5_STRMU/1-79GGLGPIAGA......AIGWDLGAISGA
LAFA_LACJO/1-70..ACAVAGA.HYLPILWTAVTAATGGF
A5LX13_STREE/1-73..VAGLAGA......FVGAHIGAIGGG
A5MYA6_STREE/1-54..LGYVAGS......IVDTAIDDFTNQ
Q2MDB2_BACCE/1-70..IGTGIGG......AIGGVSGGLTGA
Q9ZEU9_LACPN/1-65..TGALAGA......IWGVSQCASNNL
F0TH60_LACA3/1-61..WGAVIGG......VGGAAVCGLAGY
O85757_9LIST/1-56..LGGLGGA......GGGCITGAIGSI
Q5LYA7_STRT1/1-74..PGYLAGG......VLGGAGGTVAYG
I6U3Y5_STRMG/1-63..GGNPVGG......VLGIA.GGLDAY
Q035H7_LACC3/1-68..FGIIGGA......VVGGNLGAVGSA
F0TH58_LACA3/1-68..VGGLGGA......LLGGSLGVIAGS
F0TH61_LACA3/1-75..GCGFVGA.HWGAVGWTAVASFSGAF
Q9XDR7_9LACO/1-70..ACGFVGA.HYVPIAWAGVTAATGGF
Q1J813_STRPF/1-76..PCSPYGT........GGTPNTCNGL

PF03047

A8B010_STRGC/1-38--DVRSNKI------------------
Q8DSB2_STRMU/1-30--MTWAEIG------------------
I6L8Z2_STRMU/1-32--SGSLSTF------------------
CSP1_STRR6/1-31--EMRLSKF------------------
Q5M2V9_STRT2/1-30--SGWMDYI------------------
Q7CRB4_STRR6/1-30--GWWEEL.------------------

PF04604

A0A029S6Z0_STRPY/1-48--DCPN...----------..SVFVCC
A0FL76_9ENTE/1-51--DCPNVIS----------SICAGTII
G2GW18_STRSL/1-56--ECNL.AT----------WTKKLKCC
LANB_STRP9/1-50--ECHL.NT----------WAFLATCC
A0SXQ1_STRMG/1-50--ECRY.NS----------WAFLATCC
O85355_BUTFI/1-47--ECHM.NT----------WQFIFTCC
A0SXQ2_STRMG/1-53--DCRW.NS----------LQAIFSCC
LANA_STRMG/1-53--ECRM.NS----------WQHVFTCC
LANA_RUMGN/1-47--ECNM.NT----------WQFLFTCC
P71449_9LACT/1-50--EVIY.NS----------WNFVFTCC
A6MER2_STRMC/1-53--ECRW.NS----------LQAIFSCC
Q50848_KOCVA/1-46--ECHM.NS----------FQFVFTCC
LANNA_STASI/1-56--DCHM.NS----------FQFVFTCC
O31051_STRPY/1-51--ECRW.NS----------LQAIFTCC
Q09II3_STRSL/1-55--ECRM.NS----------WQFLFTCC

PF04369

K7WBI6_LACLC/1-60--VYQQTQN------AFGAAANTIV--
Q7X5J4_LEUME/1-53--GPQQPNS------PWLAKIKNHK--
K7VRC1_LACLC/1-60--ICKQTID------TASYTFGVMA--

PF08129

Q9L9U6_ENTFL/1-57--LGNMSDV-------NQADRINRKKH
Q8VPA2_ENTFL/1-57--LGNMSDV-------NQADRINRKKH

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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