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112  structures 6809  species 6  interactions 346019  sequences 285  architectures

Clan: BPD_transp_1 (CL0404)


BPD transporter like Add an annotation

This clan contains families that are involved in transport of molecules across membranes. It includes the bacterial binding protein-dependent transport system inner membrane component, Pfam:PF00528, which is ATP dependent system involved in transport of a range of substrates [1-2].

This clan contains 4 families and the total number of domains in the clan is 346019. The clan was built by J Mistry and RD Finn.

Literature references

  1. Higgins CF, Hyde SC, Mimmack MM, Gileadi U, Gill DR, Gallagher MP; , J Bioenerg Biomembr 1990;22:571-592.: Binding protein-dependent transport systems. PUBMED:2229036 EPMC:2229036
  2. Ames GF;, Annu Rev Biochem. 1986;55:397-425.: Bacterial periplasmic transport systems: structure, mechanism, and evolution. PUBMED:3527048 EPMC:3527048


This clan contains the following 4 member families:

BPD_transp_1 DUF1430 FtsX LptF_LptG

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
BPD_transp_1 (PF00528) 288114 (83.3%) View
FtsX (PF02687) 50016 (14.5%) View
LptF_LptG (PF03739) 7769 (2.2%) View
DUF1430 (PF07242) 120 (0.0%) View
Total: 4 Total: 346019 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 6 interactions for this clan. More...

Interacting families
ABC_tran BPD_transp_1
BPD_transp_1 ABC_tran
MalF_P2 BPD_transp_1
SBP_bac_1 BPD_transp_1


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...