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264  structures 1172  species 4  interactions 8049  sequences 369  architectures

Clan: Fibrinogen_C (CL0422)


Fibrinogen C-terminal domain-like Add an annotation

This is a collection of families with C-terminal domains that are of similar structure.

This clan contains 2 families and the total number of domains in the clan is 8049. The clan was built by RD Finn.


This clan contains the following 2 member families:

COLFI Fibrinogen_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Fibrinogen_C (PF00147) 6289 (78.1%) View
COLFI (PF01410) 1760 (21.9%) View
Total: 2 Total: 8049 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 4 interactions for this clan. More...

Interacting families
Collagen Fibrinogen_C
Fib_alpha Fibrinogen_C
Fibrinogen_C Fib_alpha


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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