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18  structures 56077  species 7  interactions 182164  sequences 81  architectures

Clan: ComplexI-N (CL0425)


NADH dehydrogenase I, subunit N Add an annotation

This superfamily contains proteins from the families Oxidored_q1 and NADHdeh_related. The Oxidored_q1 family is part of complex I which catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane. Many members of the NADHdeh_related family are archaeal and bacterial, indicating the evolutionary origins of ComplexI.

This clan contains 2 families and the total number of domains in the clan is 182164. The clan was built by A Bateman.


This clan contains the following 2 member families:

NADHdeh_related Proton_antipo_M

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Proton_antipo_M (PF00361) 182124 (100.0%) View
NADHdeh_related (PF10125) 40 (0.0%) View
Total: 2 Total: 182164 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 7 interactions for this clan. More...

Interacting families
Oxidored_q2 Proton_antipo_M
Oxidored_q3 Proton_antipo_M
Oxidored_q4 Proton_antipo_M
Proton_antipo_M Oxidored_q2
Proton_antipo_N Proton_antipo_M


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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