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38  structures 202  species 3  interactions 2099  sequences 104  architectures

Clan: FimbA (CL0450)


Fimbriae A and Mfa superfamily Add an annotation

To add the reference from ActaF when it is published, A conserved fold for fimbriae components revealed by the crystal structure of a putative fimbriae assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Angstrom resolution. This family includes the fimbrillin-A set of fimbrial proteins and the shorter Mfa1 fimbrial set and their asoociated anchor-proteins Mfa2.

This clan contains 6 families and the total number of domains in the clan is 2099. The clan was built by Q XuRD Finn and P Coggill.


This clan contains the following 6 member families:

DUF4906 DUF5119 Mfa2 Mfa_like_1 Mfa_like_2 P_gingi_FimA

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Mfa_like_1 (PF13149) 1160 (55.3%) View
Mfa2 (PF08842) 461 (22.0%) View
DUF4906 (PF16249) 188 (9.0%) View
P_gingi_FimA (PF06321) 182 (8.7%) View
DUF5119 (PF17145) 103 (4.9%) View
Mfa_like_2 (PF15415) 5 (0.2%) View
Total: 6 Total: 2099 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
Mfa2 Mfa2
Mfa_like_1 Mfa_like_1
P_gingi_FimA P_gingi_FimA


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...