Sequence alignment for CL0451

PF00093

TSP2_MOUSE/320-374-----------------CV.QE-GRIFAENETWVVDS........CT.TCTCKK........FK---TVCHQIT..CSP.
VWF_HUMAN/2431-2494-----------------CV.HR-STIYPVGQFWEEG.........CD.VCTCTDMEDAVMGLRV---AQCSQKP..CE..
VWF_HUMAN/2257-2325-----------------CIGED-GVQHQFLEAWVPDHQ......PCQ.ICTCLS.......GRK---VNCTTQP..CPTA
VWF_HUMAN/2582-2644-----------------CM.LN-GTVIGPGKTVMIDV........CT.TCRCMVQVG.VISGFK---LECRKTT..C...
CO1A1_HUMAN/40-95-----------------CV.QN-GLRYHDRDVWKPEP........CR.ICVCDN........GK---VLCDDVI..CDE.
CO5A2_HUMAN/41-96-----------------CT.QN-GQMYLNRDIWKPAP........CQ.ICVCDN........GA---ILCDKIE..CQD.
CO1A1_CHICK/33-88-----------------CV.QD-GLTYNDKDVWKPEP........CQ.ICVCDS........GN---ILCDEVI..CED.
CO3A1_MOUSE/33-89-----------------CS.HL-GQSYESRDVWKPEP........CQ.ICVCDS........GS---VLCDDII..CDEE
SOG_DROME/941-1019-----------------CK.VV-NKVYENGQEWHPILMSH.GEQKCI.KCRCKD........SK---VNCDRKR..CSR.
TSP1_HUMAN/318-372-----------------CY.HN-GVQYRNNEEWTVDS........CT.ECHCQN........SV---TICKKVS..CPI.
TSP2_CHICK/326-380-----------------CW.QD-GRVFADSESWIVDS........CT.KCTCQD........SK---IVCHQIT..CPP.
CYR61_CHICK/100-163-----------------CE.YN-SKIYQNGESFQPN.........CKHQCTCID........GA---VGCIPL...CPQE
NOV_CHICK/106-169-----------------CV.FD-GMIYRNGETFQPS.........CKYQCTCRD........GQ---IGCLPR...CNLG
SOG_DROME/832-898-----------------CR.LG-EQFHPAGASWHPFLPPN.GFDTCT.TCSCDPL......TLE---IRCPRLV..CPP.
CO2A1_MOUSE/34-88-----------------CL.QN-GQRYKDKDVWKPSS........CR.ICVCDT........GN---VLCDDII..CED.
SOG_DROME/744-803-----------------CF.HS-GRFYNESEQWRSAQD......SCQ.MCACLR........GQ---SSCEVIK..CPA.
CTGF_HUMAN/103-166-----------------CI.FG-GTVYRSGESFQSS.........CKYQCTCLD........GA---VGCMPL...CSMD
SOG_DROME/102-174-----------------CQ.FG-KVLRELGSTWYADLGPPFGVMYCI.KCECVAIPKKRRIVAR---VQCRNIKNECPP.
F6XC33_XENTR/326-380-----------------CL.HN-GVLHKNRDEWTVDS........CT.ECTCQN........SA---TICRKVS..CPL.

PF12714

F5H4B5_HUMAN/1094-1148----------------NCF.YN-NDYYEPGAEWFSPN.-------CTEHCRCWP-------GSR---VECQISQ--CGT-
F5H4B5_HUMAN/1480-1535----------------GCLHPA-GSYFKVGERWYKPG.-------CKELCVCES-------NNR---IRCQPWR--CRA-
C3YHS2_BRAFL/245-297----------------PPCYFH-GNAYPSGEWWTY...-------ACKECTC.E-------CGQ---VVCQPVQ--CPP-
C3YHS2_BRAFL/348-403----------------PPCYVN-GNVIPSGEWWTNTIT-------ACTECTC.L-------CGQ---VQCQPIK--CPP-
ZAN_MOUSE/1221-1275----------------NCP.YN-NKHYKPGEEWFTPN.-------CTERCRCLP-------GSL---MECQISQ--CGT-
ZAN_MOUSE/1609-1664----------------GCTSFQ-GRYFKLQEQWFNPD.-------CKEICTCES-------HNH---ILCKPWK--CKA-
ZAN_MOUSE/2399-2454----------------GCKDAQ-GVFIPAGKTWISED.-------CTQSCTC.M-------KGS---MRCWDFQ--CPP-
ZAN_MOUSE/2519-2574----------------GCQHTQ-GGFIPAGKNWTSRG.-------CSQSCDC.M-------EGV---IRCQNFQ--CPS-
ZAN_MOUSE/2639-2694----------------GCKDAQ-GVLIPADKIWINKG.-------CTQTCAC.V-------TGT---IHCRDFQ--CPS-
ZAN_MOUSE/2759-2814----------------GCKDAQ-GVLIPAGKTWINRG.-------CTQSCSC.M-------GGA---IQCQNFK--CPS-
ZAN_MOUSE/2879-2934----------------GCKDTQ-GVLIPADKTWINRG.-------CTQSCTC.R-------GGA---IQCQKYH--CSS-
ZAN_MOUSE/3119-3174----------------GCKDAQ-GALIPEGKTWITSG.-------CTQSCNC.T-------GGA---IQCQNFQ--CPL-
ZAN_MOUSE/3239-3294----------------GCKNTQ-GAFISADKTWISRG.-------CTQSCTC.P-------AGA---IHCRNFK--CPS-
ZAN_MOUSE/3356-3411----------------GCKDAR-GAIIPAGKTWTSKG.-------CTQSCAC.V-------EGN---IQCQNFQ--CPP-
ZAN_MOUSE/3476-3531----------------DCKDAQ-GALIPAGKTWTSPG.-------CTQSCAC.M-------GGA---VQCQSSQ--CPP-
ZAN_MOUSE/3596-3651----------------GCKDAH-GALIPEDKTWVSRG.-------CTQSCVC.T-------GGS---IQCLSSQ--CPP-
ZAN_MOUSE/3836-3887----------------GCRDTQ-GAVIPAGKTWLSTG.-------CIQSCAC.V-------EGT---IQCQNFQ--CPP-
ZAN_MOUSE/3952-4007----------------DCKDAE-GGLVPAGKTWTSKD.-------CTQSCAC.T-------GGA---VQCQNFQ--CPL-
ZAN_MOUSE/4088-4143----------------GCKDTQ-GGLIPAGRTWISSD.-------CTKSCSC.M-------GGI---IQCRDFQ--CPP-
ZAN_MOUSE/4208-4258----------------GCKDAQ-GGFVPAGKTWISRG.-------CTQSCAC.V-------GGA---VQCHNFT--CPT-
ZAN_MOUSE/4323-4378----------------GCKDAQ-GDLIPANKTWLTRG.-------CAQKCTC.K-------GGN---IHCWNFK--CPL-
ZAN_MOUSE/4443-4498----------------GCKDSQ-GTLIPAGKNWITTG.-------CSQRCTC.T-------GGL---VQCHDFQ--CPS-
ZAN_MOUSE/4563-4618----------------GCKDAH-GVLIPESKTWVSRG.-------CTKNCTC.K-------GGT---VQCHDFS--CPT-
ZAN_MOUSE/4683-4738----------------DCKDFQ-GSLIKTGQTWISSG.-------CSKICTC.K-------GGF---FQCQSYK--CPS-
ZAN_MOUSE/4803-4858----------------GCKDIR-GNIIPAGNTWISSD.-------CTQSCAC.T-------DGV---IQCQNFV--CPS-
ZAN_MOUSE/5204-5258----------------GCT.AD-GIYYKLGDSFVTND.-------CSQHCTCAS-------QGI---LLCEPYG--CRA-
ZAN_RABIT/551-605----------------PCL.YN-NNNYEPEAEWFSPN.-------CTELCHCWP-------GGR---IECQISQ--CKT-
ZAN_RABIT/935-990----------------GCLDPS-RGYFKVGEQWFKSD.-------CKQLCICEG-------SNQ---IRCQPWK--CGP-
ZAN_RABIT/1323-1379----------------GCTDFE-GSYHLVRESWYTDNT-------CSRLCTCSL-------HNN---ITCRQTA--CKP-
ZAN_RABIT/1727-1782----------------SCRDAQ-GGSIPSGKSWVSSG.-------CSQKCAC.T-------EGS---IQCRAFH--CPS-
ZAN_RABIT/2130-2184----------------GCT.SN-GIYYQLGHSFVTAD.-------CSQRCTCAS-------SGV---LLCEPFS--CRP-
ZAN_PIG/740-794----------------DCF.YN-DNYYKLGTDWFSPN.-------CTEHCHCRP-------SSR---MECQTFK--CGT-
ZAN_PIG/1512-1568----------------GCTTQR-GSYHPVGESWYTDNS-------CSRLCTCSA-------HNN---ISCRQAS--CKP-
ZAN_PIG/1908-1963----------------GCRDAR-GTFLPVGRFRLSSG.-------CSQMCVC.T-------AGA---IECRPFT--CPS-
H3CDL3_TETNG/143-198----------------.ATTRT-ESYRPVGDTWFTSKN-------CSERCKCNG-------NHN---VTCEPWQ--CSP-

PF00039

F1RB09_DANRE/2278-2315-----------------CHDS..GNNYRIGEKWERRAE.NG.---HLMSCTCLG-----NGKGE---FKC----------
C3ZFJ5_BRAFL/40-77-----------------CTAN..GQTYQIGQQWYMTNQ.AG.---YMLICTCEG-----NGQGH---YSC----------
TPA_BOVIN/42-79-----------------CRDGKTQMTYRQHDSWLRPLL.RGN---QVEHCWCDG-----...GR---AQC----------
G1PDW0_MYOLU/131-166-----------------CFEPQLLQFFHENETWHRLEP.AG.---.MAECQCQG-----...PQ---AHC----------
G1SIB7_RABIT/147-182-----------------CFEPQLHRFFHENDMWYRFER.AG.---.VAKCRCKG-----...PD---AHC----------
F1RB09_DANRE/569-607-----------------CQEPETKVFYQIGQTWNKVIQ..G.---TPYRCSCYG-----NGIGE---MAC----------
F6ZE17_ORNAN/67-102-----------------CMDYTTKKVYQQRESWLRH...RGA---QLEYCRCDS-----...GL---ARC----------
I3ME10_SPETR/41-78-----------------CRDEKTQMIYQQHESWLRPML.RSN---RVEYCWCNS-----...GR---PQC----------
W5KP40_ASTMX/566-604-----------------CQEPESKAFYQIGETWDKVIQ..G.---IRYRCYCHG-----NGIGE---QAC----------
F1RB09_DANRE/526-563-----------------CVVN..GQTYDVNETFDKRHD.QG.---YMMNCTCFG-----QGRGR---WKC----------
H2N233_ORYLA/230-269-----------------CNDQDVLKSYRIGDTWTKTDA.RG.---NLLQCLCMG-----NGRGQ---WKC----------
H3A822_LATCH/534-572-----------------CQDSETRHFYQIGEAWDKVVH..G.---IRYQCYCFG-----RGVGE---WSC----------
H3CVR7_TETNG/456-495-----------------CTTSD.GVMHRVGDKWDKRHDVGG.---HMMQCTCLG-----NGRGE---WSC----------
G3NY30_GASAC/467-506-----------------CTSSE.GVMYRMGEQWDKRHDILG.---HMMRCTCVG-----NGRGE---WSC----------
W5MV81_LEPOC/114-152-----------------CYDKINGRTYRVGETYERPKD..G.---MIWDCTCIG-----SGRGK---ISC----------
H3A822_LATCH/204-243-----------------CNDQDTRNSYRIGETWSKTDA.RG.---HPLQCVCNG-----NGRGE---WTC----------
B8Y9T0_BOVIN/519-556-----------------CIVD..GITYNVNDTFHKRHE.EG.---HMLNCTCFG-----QGRGR---WKC----------
L9JG25_TUPCH/135-170-----------------CFEPQLLRFFHEDEIWHRAEP.GG.---.VARCQCRG-----...PD---AHC----------
M3ZI24_XIPMA/181-220-----------------CFDSYSGSSYLVGETWERPYQ..GW---MMLDCTCYG-----EGNGR---ISC----------
H2LFT1_ORYLA/182-221-----------------CYDNSASSSYAVGETWEKQYQ..GW---MMLDCTCLG-----EGHGK---IQC----------
M3ZI24_XIPMA/136-174-----------------CHDS..GRSYKIGETWQKPHE.SGE---YLLECVCLG-----NNKGE---WTC----------
H2LFT1_ORYLA/567-605-----------------CQEPQNRVFYQIGEQWDKVIH..G.---VQYRCHCYG-----NGIGE---MSC----------
B8Y9T0_BOVIN/2088-2127-----------------CFDPYTVSHYAIGEEWERLSD.SG.---FKLSCQCLG-----FGSGH---FRC----------
U3IZ83_ANAPL/2248-2287-----------------CYDTFTGSFYSIGEEWERLSE.TG.---FKLWCQCLG-----FGSGH---FRC----------
B8Y9T0_BOVIN/471-509-----------------CTTNE.GVMYRIGDQWDKQHD.MG.---HMMRCTCVG-----NGRGE---WTC----------
I3J5Q8_ORENI/94-130-----------------CYDKYNERTYQVGETYEKLLE..R.---MTWDCTCIG-----S..GK---ISC----------
M3ZI45_XIPMA/87-125-----------------CYDKLGQKFYSVGETFESSKD..G.---MTWDCTCIG-----SGKGR---ISC----------
B8Y9T0_BOVIN/98-136-----------------CFDKYTGNTYRVGDTYERPKD..S.---MIWDCTCIG-----AGRGR---ISC----------
M3ZI24_XIPMA/549-587-----------------CRDQQNNAIYQIGEQWDKVIS..G.---YHYRCTCFG-----KGRGE---MGC----------
M3ZI45_XIPMA/554-592-----------------CQDPETRTIYQVGESWDKVIQ..G.---VMYKCICYG-----NGVAE---HGC----------
G1M8F9_AILME/197-232-----------------CFDETRYEHLEVGDRWARVSQ..G.---QVEQCECAG-----...GQ---IRC----------
W5MV81_LEPOC/582-620-----------------CQEPETRVFYQVGESWDKVIH..G.---IQYKCYCYG-----NGIGE---LSC----------
M3ZI45_XIPMA/175-214-----------------CVDQAVGTSYVVGEKWEKQYQ..GW---MIIDCICLG-----EGNGL---ITC----------
H3A822_LATCH/25-60-----------------CYDN..GRYYMVNQQWERTYL..G.---NLLVCTCYG-----SSQG.---FNC----------
H3CVR7_TETNG/227-266-----------------CNDQDTRRAYRIGDTWTKPDS.SG.---YTLQCQCLG-----NARGE---WKC----------
TPA_RAT/38-75-----------------CRDEQTQTTYQQHQSWLRPML.RGN---RVEYCRCNS-----...GL---AQC----------
W5MV81_LEPOC/2260-2299-----------------CYDTFTATYHEVGAEWERMSE.TG.---FKLWCTCLG-----FGSGH---FRC----------
B8Y9T0_BOVIN/2133-2170-----------------CHDN..GVNYKIGEKWDRQGE.NG.---QMMSCTCLG-----NGKGE---FKC----------
F1MTT3_BOVIN/135-170-----------------CFEPQFFRFFHENEIWHRLEP.AG.---.VVKCQCKG-----...PN---AQC----------
H3CVR7_TETNG/549-587-----------------CQEPQTRSFYQIGESWDKVLH..N.---TRYRCYCYG-----NGIGE---MSC----------
B8Y9T0_BOVIN/232-271-----------------CNDQDTRTSYRIGDTWSKKDN.RG.---NLLQCICTG-----NGRGE---WKC----------
I3J5Q8_ORENI/546-584-----------------CQEPQTRTFYQIGETWDKAIH..G.---IYYRCYCYG-----NGIGE---MRC----------
FA12_MOUSE/135-170-----------------CFEPQLLKFFHENELWFRTGP.GG.---.VARCECKG-----...SE---AHC----------
I3J5Q8_ORENI/226-265-----------------CNDQETRRSYRIGDTWTRTDT.SG.---HRLQCVCLG-----NGRGE---SKC----------
B8Y9T0_BOVIN/53-88-----------------CYDN..GKHYQINQQWERTYL..G.---SALVCTCYG-----GSRG.---FNC----------
H2QS39_PANTR/135-170-----------------CFEPQLLRFFHKNEIWYRTEQ.AA.---.VARCQCKG-----...PD---AHC----------
B8Y9T0_BOVIN/562-600-----------------CQDSETRTFYQIGDSWEKYLQ..G.---VRYQCYCYG-----RGIGE---WAC----------
G5BQ09_HETGA/136-171-----------------CFEPQLLRFFHENEIWLKTGS.AG.---.VAKCHCKG-----...PD---AHC----------
H3A822_LATCH/2253-2292-----------------CYDTYSSTYHAVGEEWERMSE.TG.---FKLWCQCIG-----MGNGH---FRC----------
I3M114_SPETR/2341-2378-----------------CYDN..GVNYKIGEKWTRRAD.TG.---EMLSCTCLG-----NGKGE---FKC----------
M3ZI45_XIPMA/220-259-----------------CNDQDTRASYRVGDRWTKIDP.KG.---HQLQCICNG-----NGRGE---MKC----------
M3ZI24_XIPMA/226-265-----------------CNDLQTRRSFGIGDTWTKTDD.KG.---NAMKCVCLG-----NGRGE---SNC----------
M3ZI24_XIPMA/506-543-----------------CVVD..GLTYEVNQQFSKRHN.EG.---HMMNCTCFG-----LGRGY---WKC----------
B8Y9T0_BOVIN/2177-2212-----------------CYDD..GKTYHVGEQWQKEYL..G.---AICSCTCFG-----GQRG.---WRC----------
B8Y9T0_BOVIN/142-180-----------------CHEG..GQSYKIGDTWRRPHE.TGG---YMLECVCLG-----NGKGE---WTC----------
F1RB09_DANRE/190-229-----------------CYDDSLGSSYVVGQTWQKPYQ..GW---MIVDCTCLG-----EGNGR---ITC----------
M3ZI24_XIPMA/94-130-----------------CYDKDNARTYRVGEIYERPKD..G.---FMWDCTCVS-----S..GK---ISC----------
B8Y9T0_BOVIN/187-226-----------------CFDQAAGTSYVVGETWEKPYQ..GW---MMVDCTCLG-----EGSGR---ITC----------
W5KP40_ASTMX/234-273-----------------CNDQDTRKSYRIGETWSKVDT.NG.---HRLQCLCTG-----NGRGE---WKC----------
F7D3F1_XENTR/2297-2336-----------------CYDTFNGAHYSVGQEWERMSE.SG.---FRLWCKCLG-----YGSGH---FRC----------
W5MV81_LEPOC/539-576-----------------CIVD..GLTYEVNQTFTKRHD.EG.---YMMNCTCYG-----QGRGR---WKC----------
H3CVR7_TETNG/2138-2173-----------------CYDN..GQAYQVGNQWQKEYM..G.---AICTCTCFG-----GQQG.---WRC----------
H2N233_ORYLA/185-224-----------------CYDSSAGASYLVGETWEKPYQ..GW---MVMDCTCLG-----QGNGQ---ITC----------
H2V3X7_TAKRU/181-220-----------------CYDTDASSSYVVGETWEKRYQ..SW---MMLDCTCLG-----EGNGR---ITC----------
I3J5Q8_ORENI/181-220-----------------CYDNSAAATYAVGDTWEKPYQ..GW---MMLDCTCMG-----EGNGR---ITC----------
F6WLY7_MONDO/37-74-----------------CKDEKTQMIYQQKQSWLRPGL.RGN---RVEYCRCDS-----...GF---IRC----------
M3Y301_MUSPF/117-154-----------------CRDEKTQTLYLQNESWLRPGL.RGN---RVEYCRCVG-----...GR---PHC----------
G3HHH6_CRIGR/241-278-----------------CRDEQTQTTYQHLQSWLRPML.RSS---RVEYCRCNG-----...GS---TQC----------
H2LFT1_ORYLA/227-266-----------------CNDNTVKKSFRIGETWMKTDL.SG.---HRVECLCLG-----NGRGE---WKC----------
G5BT55_HETGA/38-75-----------------CRDEKTQMTYQQHESWLRPLL.RGN---RVEFCWCNG-----...GR---PQC----------
I3M114_SPETR/2296-2335-----------------CFDPYSASHYDIGDEWERISE.TG.---FKLTCQCLG-----FGSGH---FRC----------
F1RB09_DANRE/478-516-----------------CTVN..DVMYRVGDEWDKRHDTLG.---HMMRCTCQG-----NGRGE---WNC----------
W5KP40_ASTMX/144-182-----------------CHEG..GRSYRIGEKWTRPHD.TGD---YMLECVCLG-----NGKGE---WTC----------
U3INV8_ANAPL/121-156-----------------CFDNSLYEYFDVGMTWSRVQQ..G.---AVEQCTCVD-----...GE---IEC----------

PF05375

P91776_PACLE/166-204----------------ECEGTP-------TWTKG....-------.CNTCSCV.-------NGS...AQCTTEE--CDK-
CVP4_PIMHY/87-128----------------PC..TP-------GENFK.YY.-------.CNDCQCL.-------DGLRAHAMCTRMR--CDR-
CVP4_PIMHY/149-191----------------SC..AP-------GASFK.YY.-------.CNSCTCGA-------EGKVAEAQCTSQE--CDR-
CVP4_PIMHY/25-66----------------TC..EI-------GSNFK.NY.-------.CNNCYCF.-------DGVMDHALCTRES--CDR-
A2CKF3_TRIIF/22-62----------------YC..EP-------NTRFK.QE.-------.CNWCTCSA-------NGEY..ATCTLLY--CGP-
P91776_PACLE/75-114----------------VC..SE-------GSRWKADD.-------.CNWCRCI.-------DGS...PSCTKRL--CRT-
Q17NZ1_AEDAE/98-138----------------VC..TP-------NEVKM.ED.-------.CNRCKCAA-------NGIG..WFCTRKA--CPP-
P91776_PACLE/231-270----------------QC..VP-------GSRWK.KD.-------.CNWCSCTE-------TAI...GMCTLIG--CLN-
Q5K4F7_SCHGR/25-64----------------GC..TP-------GEKKK.ED.-------.CNTCTCTA-------TGV...WACTRRG--CIT-
Q95PM3_SCHGR/61-95----------------NC..TP-------GTTFK.NK.-------.CNTCRCGS-------NGRS..ASCTLMA--CPP-
Q8WQ21_LOCMI/123-163----------------HC..TP-------NTTFQ.KD.-------.CNTCTCNK-------DGTA..AVCTLKA--CLK-
Q7QHR7_ANOGA/29-68----------------KC..EP-------GTTFM.ED.-------.CNKCRCGP-------DGQ...KACTRKM--CPP-
Q8MYK3_SCHGR/24-63----------------EC..TP-------GETKK.LD.-------.CNTCFCSD-------SGI...WGCTLMG--CRT-
Q17NZ1_AEDAE/23-63----------------QC..EP-------GSTFK.LD.-------.CNTCRCGA-------DGKV..MSCTRKF--CVP-
P91776_PACLE/312-351----------------MC..VP-------GSRWK.DE.-------.CNWCWCEA-------NGA...APCTRMG--CSE-
Q17NZ1_AEDAE/253-294----------------QC..VP-------GTSFK.SAD-------GCNDCFCSA-------NGM...AACTLRF--CFF-
Q8WQ21_LOCMI/75-115----------------QC..TP-------GTTFK.KD.-------.CNTCSCGN-------DGTA..AVCTLKA--CRE-
P91776_PACLE/353-386----------------VC..ID-------GSRWK.VD.-------.CNWCTCN.-------NGS...SACTEKL--CL.-
P91776_PACLE/34-73----------------LC..AP-------GSRWK.NE.-------.CNWCSCAD-------HGL...ALCTLMG--CFP-
Q8WQ21_LOCMI/24-63----------------EC..TP-------GETKK.LD.-------.CNTCFCTK-------AGI...WGCTLMA--CRT-
LCM_LOCMI/22-61----------------KC..TP-------GQVKQ.QD.-------.CNTCTCTP-------TGV...WGCTRKG--CQP-
Q8WQ22_LOCMI/72-112----------------QC..TP-------NKSFK.KD.-------.CNTCTCNK-------DGTA..AICTQIA--CLN-
Q19Q50_9DIPT/44-82----------------NC..EN-------GESYF.DG.-------.CNTCTCK.-------NGA...YSCTLKA--CYT-
P91776_PACLE/121-162----------------ECYGDP-------DTNRWRIE.-------.CNWCRCV.-------NGK...GSCTRKG--CPQ-
Q19Q50_9DIPT/96-134----------------GC..DK-------GQSYF.DG.-------.CNTCVCG.-------NGV...YACTLKA--CFN-
Q17NZ1_AEDAE/316-350----------------SC..SP-------GKSFK.YQ.-------.CNTCRCDT-------SGQT..AACTFKF--CLP-
Q5K4F7_SCHGR/72-112----------------KC..TP-------NSTFK.KD.-------.CNTCTCNS-------SGTS..AICTQLG--CLS-
P91776_PACLE/271-309----------------VC..TD-------GSKWK.DD.-------.CNWCTCN.-------NGS...ASCTEKL--CQY-
Q7QHR7_ANOGA/77-117----------------VC..SP-------NEIKM.KD.-------.CNRCRCAN-------NGIG..WFCTRRA--CPQ-
P91776_PACLE/387-420----------------QC..TE-------GESWR.QD.-------.CNMCSCS.-------TGL...RICSVKG--CPP-
SGP1_SCHGR/22-61----------------EC..TP-------GQTKK.QD.-------.CNTCNCTP-------TGV...WACTRKG--CPP-
Q17NZ1_AEDAE/156-197----------------EC..EP-------GTNFK.SAD-------GCNDCFCTA-------TGI...AACTQKF--CFN-
SGP3_SCHGR/23-62----------------AC..TP-------GSRKY.DG.-------.CNWCTCSS-------GGA...WICTLKY--CPP-
Q7QHR7_ANOGA/121-158----------------KC..TP-------GTTFR.SDD-------GCNTCFCTE-------TGH...AACTLKA--CLP-
Q8WQ22_LOCMI/25-64----------------EC..TP-------GQTKK.QD.-------.CNTCTCTP-------TGI...WGCTRKA--CRT-
Q17NZ1_AEDAE/204-245----------------EC..VP-------GTTFK.SAD-------GCNDCFCSE-------SGH...AACTMKF--CFP-

PF05825

MSMB_MOUSE/21-113VCSIENREIFPNQMSDDCMDAD-GNKHFLNTPWK.KN---------CTWCSCDK-------TSI---TCCTNAT--RPL-
MSMB_RAT/21-113ACSIQRLKRLPNEKSDECTDVD-GGKHVLNTYWQ.KN---------CEWCFCEK-------TAI---TCCTKTL--IPV-
MSMB_PIG/21-111QCYFIPNQSL...KPNECQDLK-GVSHPLNSVWKTKD---------CEECTCGQ-------NAI---SCCNTAA--IPT-
MSMB_MACMU/21-114SCSFIPNERFPGDSTRECTDLK-GNKHPINSKWKTDN---------CERCTCYK-------TEI---ICCTLIA--TPV-

PF00093

TSP2_MOUSE/320-374.....ATCANP................SFVEGECCP..SC--
VWF_HUMAN/2431-2494.....DSCRSG.............FTYVLHEGECCG..RC--
VWF_HUMAN/2257-2325KAPTCGLCEVA..............RLRQNADQCCPEYEC--
VWF_HUMAN/2582-2644.....NPCPLG.............YKEENNTGECCG..RC--
CO1A1_HUMAN/40-95....TKNCPGA................EVPEGECCP..VC--
CO5A2_HUMAN/41-96....VLDCADP................VTPPGECCP..VC--
CO1A1_CHICK/33-88....TSDCPNA................EIPFGECCP..IC--
CO3A1_MOUSE/33-89....PLDCPNP................EIPFGECCA..IC--
SOG_DROME/941-1019.....STCQQQTRVTSKRRLFEKPDAAAPAIDECCS.TQC--
TSP1_HUMAN/318-372.....MPCSNAT............VP....DGECCP..RC--
TSP2_CHICK/326-380.....VSCADP.............SF...IEGECCP..VC--
CYR61_CHICK/100-163LSLPNLGCPSP..............RLVKVPGQCCEEWVC--
NOV_CHICK/106-169LLLPGPDCPFP..............RKIEVPGECCEKWVC--
SOG_DROME/832-898.....LQCSEK.............LAYRPDKKACCK..IC--
CO2A1_MOUSE/34-88.....PDCLNP................EIPFGECCP..IC--
SOG_DROME/744-803.....LKCKST.............EQLLQRDGECCP..SC--
CTGF_HUMAN/103-166VRLPSPDCPFP..............RRVKLPGKCCEEWVC--
SOG_DROME/102-174.....AKCDDP................ISLPGKCCK..TC--
F6XC33_XENTR/326-380.....MPCTNA................TIPDGECCP..RC--

PF12714

F5H4B5_HUMAN/1094-1148----HTVCQLK-----------------.NGQYGCH------
F5H4B5_HUMAN/1480-1535----QEFCGQQ-----------------.DGIYGCH------
C3YHS2_BRAFL/245-297----VTVPTCE-----------------.NGAVLEE------
C3YHS2_BRAFL/348-403----VTVPECV-----------------.NGAEPEY------
ZAN_MOUSE/1221-1275----HTVCQLK-----------------.SDQYQCE------
ZAN_MOUSE/1609-1664----QEACSYK-----------------.NGVLGCH------
ZAN_MOUSE/2399-2454----GTYCKNS-----------------NDGSSNCV------
ZAN_MOUSE/2519-2574----GTYCQDI-----------------EDGTSNCA------
ZAN_MOUSE/2639-2694----GTYCKDI-----------------KDDASNCT------
ZAN_MOUSE/2759-2814----EAYCQDM-----------------EDGNSNCT------
ZAN_MOUSE/2879-2934----GTYCKDM-----------------EDDSSSCA------
ZAN_MOUSE/3119-3174----KTYCKDL-----------------KDGSSNCT------
ZAN_MOUSE/3239-3294----GTYCKNG-----------------DNGSSNCT------
ZAN_MOUSE/3356-3411----ETYCKDN-----------------SEGSSTCT------
ZAN_MOUSE/3476-3531----GTYCKDN-----------------EDGNSNCA------
ZAN_MOUSE/3596-3651----GAYCKDN-----------------EDGSSNCA------
ZAN_MOUSE/3836-3887----GTYC...-----------------.NHNNNCA------
ZAN_MOUSE/3952-4007----GTYCKDS-----------------GDGSSNCT------
ZAN_MOUSE/4088-4143----GTYCKES-----------------NDSSRTCA------
ZAN_MOUSE/4208-4258----GTQCQ..-----------------...NSSCS------
ZAN_MOUSE/4323-4378----GTECKDS-----------------VDGGSNCT------
ZAN_MOUSE/4443-4498----GAECQDI-----------------EDGNSNCV------
ZAN_MOUSE/4563-4618----GSRCLDN-----------------NEGNSNCV------
ZAN_MOUSE/4683-4738----GTQCEES-----------------EDGSSNCV------
ZAN_MOUSE/4803-4858----GSHCQYN-----------------EDGSSDCA------
ZAN_MOUSE/5204-5258----GESCMVA-----------------.NFTRGCF------
ZAN_RABIT/551-605----HTKCQLK-----------------.NGQYECQ------
ZAN_RABIT/935-990----HEVCSQQ-----------------.SGIYGCH------
ZAN_RABIT/1323-1379----GQQCWAV-----------------.DGLLRCR------
ZAN_RABIT/1727-1782----RSHCKLN-----------------SNGNSNCV------
ZAN_RABIT/2130-2184----GESCTLG-----------------.NLTRGCF------
ZAN_PIG/740-794----HTVCQLK-----------------.NGQYGCH------
ZAN_PIG/1512-1568----SQMCWPQ-----------------.DGLIRCR------
ZAN_PIG/1908-1963----GSQCEPN-----------------EDGKDFCQ------
H3CDL3_TETNG/143-198----AQECKVV-----------------.DGLLDCH------

PF00039

F1RB09_DANRE/2278-2315------------------------------------------
C3ZFJ5_BRAFL/40-77------------------------------------------
TPA_BOVIN/42-79------------------------------------------
G1PDW0_MYOLU/131-166------------------------------------------
G1SIB7_RABIT/147-182------------------------------------------
F1RB09_DANRE/569-607------------------------------------------
F6ZE17_ORNAN/67-102------------------------------------------
I3ME10_SPETR/41-78------------------------------------------
W5KP40_ASTMX/566-604------------------------------------------
F1RB09_DANRE/526-563------------------------------------------
H2N233_ORYLA/230-269------------------------------------------
H3A822_LATCH/534-572------------------------------------------
H3CVR7_TETNG/456-495------------------------------------------
G3NY30_GASAC/467-506------------------------------------------
W5MV81_LEPOC/114-152------------------------------------------
H3A822_LATCH/204-243------------------------------------------
B8Y9T0_BOVIN/519-556------------------------------------------
L9JG25_TUPCH/135-170------------------------------------------
M3ZI24_XIPMA/181-220------------------------------------------
H2LFT1_ORYLA/182-221------------------------------------------
M3ZI24_XIPMA/136-174------------------------------------------
H2LFT1_ORYLA/567-605------------------------------------------
B8Y9T0_BOVIN/2088-2127------------------------------------------
U3IZ83_ANAPL/2248-2287------------------------------------------
B8Y9T0_BOVIN/471-509------------------------------------------
I3J5Q8_ORENI/94-130------------------------------------------
M3ZI45_XIPMA/87-125------------------------------------------
B8Y9T0_BOVIN/98-136------------------------------------------
M3ZI24_XIPMA/549-587------------------------------------------
M3ZI45_XIPMA/554-592------------------------------------------
G1M8F9_AILME/197-232------------------------------------------
W5MV81_LEPOC/582-620------------------------------------------
M3ZI45_XIPMA/175-214------------------------------------------
H3A822_LATCH/25-60------------------------------------------
H3CVR7_TETNG/227-266------------------------------------------
TPA_RAT/38-75------------------------------------------
W5MV81_LEPOC/2260-2299------------------------------------------
B8Y9T0_BOVIN/2133-2170------------------------------------------
F1MTT3_BOVIN/135-170------------------------------------------
H3CVR7_TETNG/549-587------------------------------------------
B8Y9T0_BOVIN/232-271------------------------------------------
I3J5Q8_ORENI/546-584------------------------------------------
FA12_MOUSE/135-170------------------------------------------
I3J5Q8_ORENI/226-265------------------------------------------
B8Y9T0_BOVIN/53-88------------------------------------------
H2QS39_PANTR/135-170------------------------------------------
B8Y9T0_BOVIN/562-600------------------------------------------
G5BQ09_HETGA/136-171------------------------------------------
H3A822_LATCH/2253-2292------------------------------------------
I3M114_SPETR/2341-2378------------------------------------------
M3ZI45_XIPMA/220-259------------------------------------------
M3ZI24_XIPMA/226-265------------------------------------------
M3ZI24_XIPMA/506-543------------------------------------------
B8Y9T0_BOVIN/2177-2212------------------------------------------
B8Y9T0_BOVIN/142-180------------------------------------------
F1RB09_DANRE/190-229------------------------------------------
M3ZI24_XIPMA/94-130------------------------------------------
B8Y9T0_BOVIN/187-226------------------------------------------
W5KP40_ASTMX/234-273------------------------------------------
F7D3F1_XENTR/2297-2336------------------------------------------
W5MV81_LEPOC/539-576------------------------------------------
H3CVR7_TETNG/2138-2173------------------------------------------
H2N233_ORYLA/185-224------------------------------------------
H2V3X7_TAKRU/181-220------------------------------------------
I3J5Q8_ORENI/181-220------------------------------------------
F6WLY7_MONDO/37-74------------------------------------------
M3Y301_MUSPF/117-154------------------------------------------
G3HHH6_CRIGR/241-278------------------------------------------
H2LFT1_ORYLA/227-266------------------------------------------
G5BT55_HETGA/38-75------------------------------------------
I3M114_SPETR/2296-2335------------------------------------------
F1RB09_DANRE/478-516------------------------------------------
W5KP40_ASTMX/144-182------------------------------------------
U3INV8_ANAPL/121-156------------------------------------------

PF05375

P91776_PACLE/166-204----------------------------LVQSPSVP------
CVP4_PIMHY/87-128----------------------------NVFNEDGT------
CVP4_PIMHY/149-191----------------------------YKWKKDGS------
CVP4_PIMHY/25-66----------------------------NVWNEDGT------
A2CKF3_TRIIF/22-62----------------------------RRARAVSS------
P91776_PACLE/75-114----------------------------KLAKGMFA------
Q17NZ1_AEDAE/98-138----------------------------RERRSASE------
P91776_PACLE/231-270----------------------------YEPKPGEA------
Q5K4F7_SCHGR/25-64----------------------------KREAEESP------
Q95PM3_SCHGR/61-95----------------------------......GS------
Q8WQ21_LOCMI/123-163----------------------------RSTREVSC------
Q7QHR7_ANOGA/29-68----------------------------NELSDDSQ------
Q8MYK3_SCHGR/24-63----------------------------YTLQPAPT------
Q17NZ1_AEDAE/23-63----------------------------DVQGDDPK------
P91776_PACLE/312-351----------------------------DYKPQPGE------
Q17NZ1_AEDAE/253-294----------------------------EDQPQIKS------
Q8WQ21_LOCMI/75-115----------------------------LTTDQAGS------
P91776_PACLE/353-386----------------------------....KPGG------
P91776_PACLE/34-73----------------------------GYKAAQGE------
Q8WQ21_LOCMI/24-63----------------------------INIELTPG------
LCM_LOCMI/22-61----------------------------AKREISCE------
Q8WQ22_LOCMI/72-112----------------------------RGRRQVNC------
Q19Q50_9DIPT/44-82----------------------------GPLLPDTA------
P91776_PACLE/121-162----------------------------VINGIGLA------
Q19Q50_9DIPT/96-134----------------------------GPLLLDTH------
Q17NZ1_AEDAE/316-350----------------------------......GE------
Q5K4F7_SCHGR/72-112----------------------------RGRRQVNC------
P91776_PACLE/271-309----------------------------KPDGSLPD------
Q7QHR7_ANOGA/77-117----------------------------RAKRSEPA------
P91776_PACLE/387-420----------------------------.....TPT------
SGP1_SCHGR/22-61----------------------------HKREVTCE------
Q17NZ1_AEDAE/156-197----------------------------TKTKRDTA------
SGP3_SCHGR/23-62----------------------------SSGGGLTF------
Q7QHR7_ANOGA/121-158----------------------------....PGFF------
Q8WQ22_LOCMI/25-64----------------------------TREAEEPA------
Q17NZ1_AEDAE/204-245----------------------------TPPRTKRL------

PF05825

MSMB_MOUSE/21-113-----SYDKDNCDVQFHPENCTYSVVDRKNPGKTCRVDSWTM
MSMB_RAT/21-113-----SYDKKRCQRQFHSENCTYSVVERTNPGKTCPVNGWTI
MSMB_PIG/21-111-----GYDTNKCQKILNKKTCTYTVVEKKDPGKTCDVTGWVL
MSMB_MACMU/21-114-----GYDKKKCQRIFKKEDCKYIVVEKKNPKKTCPIDQWIL

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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