Sequence alignment for CL0452

PF12718

C3ZKT3_BRAFL/7-153-KMLMLKNDKENALDRAEQAEQAMKDAQEK-----NVKLE---DEINDLNKKIRMVEDELDKAQESLKDATEQLEAATKK
E9Q454_MOUSE/7-152-KMQMLKLDKENALDRAEQAEADKKAAEDR-----SKQLE---DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK
J0DYI5_LOALO/7-152-KMQAMKIEKDNALDRADAAEEKVRQMTDK-----LERIE---EELRDTQKKMMQTENDLDKAQEDLSVANTNLEEKEKK
Q17H75_AEDAE/7-153-KMQAMKLEKDNALDRALLCEQQARDANLR-----AEKAE---EEARQLQKKIQAIENDLDQTQEALMAVNAKLEEKEKA
G4VD36_SCHMA/7-152-KMIAMKLEKENAMERAVQYEELLKKKEEE-----REKRE---SEIAELNNKMKQAQIDCDEAQETLQEQMNKLEETDKR
B6K811_SCHJY/7-148-KLNSIRAEAEEALARAEAAEESLKEKEHE-----LARKD---QELASLHKKNEDLEEQVDQLEQELKDVKEQAESESNQ
A8PRF4_MALGO/7-149-KLNSLRAEADAALERAEVAEARNKELEQD-----NLSKE---QEISSLQHKLSVLESDLENAEAKLSEAKVGKEEGESH
B0CUA0_LACBS/10-152-KLNSLRTEADNAVLRAEEAEAKNKKYEQL-----LLEKE---QEITSLQHKLSQLDAELEKAEEKVAEYKTANVDGEQT
Q5KF76_CRYNJ/10-149-ILGQ.KIEAAEA..RAEAAESENKKLNQT-----LLERD---QELASLQHKLQLAEEELEASESKVKELKAASDEGETH
A1CDA8_ASPCL/16-158-RMSALRLEADEAQNKVEELKSKVKTLEQE-----NLAKE---QEITSLNHRNQLLEGEVEKLETTLKEAKESANQSAQH
B6HMN3_PENRW/7-149-RMVSLRAEADEAHELVDELKAKVKTLEQE-----NLSKE---QEITSLNHRNQLLEEEVEKAEAALKEAKDAASQSLQH
C5FYF1_ARTOC/7-149-KIESMRLEIDDGQTKLSEQKARIKELEQE-----NLAKE---QEVTSLTHRNQLLEERVENLEATLKEAKAKASEAAQD
A6R7T4_AJECN/7-149-KMNTLRLEADDAHAKVEELQNKVKALEQE-----NLAKE---QEIKSLTHRNQLLEADVEKLEADLKDAKASASENAQH
B2B5X9_PODAN/7-149-KMTQLRLESEESAAKVEELQAKVKALEQE-----NLQKE---QEIISLTHKNSVLESEVEKYETQVKDLKSAASEGAQH
B2VZI7_PYRTR/7-149-RMEALRVEADESSARAEELKAKVKQLESE-----TTQKE---QEITSLSHKNQVLESEVEKLETQVKTYKDEAGAGAQA
Q6C081_YARLI/7-149-KMNSLRLETDAAQEKADEALEKVKAQEQE-----LLQKD---HEIQALTHKNSLLEEEVEKLEQQLSESKDAAEEGATH
E7QFZ0_YEASZ/7-149-KLNSLKLESESWQEKYEELREQLKELEQS-----NTEKE---NEIKSLSAKNEQLDSEVEKLESQLSDTKQLAEDSNNL
A7TEE8_VANPO/7-149-KLNNLKLEAESWQEKYEELKEQYKQLEQD-----NTDKE---NEIKSLSTKNQQLEEDVENLETKLTDSKQIAEDSHNL
C5DUA1_ZYGRC/7-149-KLNNLKLESESWQEKYEELKEQYKQLEQD-----NTEKE---NHIKSLTTKNQHLEEEVEKLETDLTDSKQLADESHNL
B4UN77_KLULA/7-149-KLSNLKLEAESWQDKYEELKEQVKVLEQE-----KTDNE---NLIKSLTTKNQTLEEEVETLEGQVSEHKQLAEDSTNL
Q755U4_ASHGO/7-149-KLATLKAESEQWQDKYEELKEEKKQLEDK-----NIEME---NQIKSLTVKNEHLEEELEKLESQLNEHKQLAEDSTNL
C5DMG5_LACTC/7-149-KLSNLKLEAESWQEKYEEVKEQMKQLEQE-----NTEKE---NQIKSLTTKNQQLEDEVEKLEGELSEHKQLSEDSHNL
Q6FKV5_CANGA/7-149-KLTNLKLEAESWQEKYEELKEQMKQLEQD-----NIQKE---NEIKSLTVKNQQLDQEVEKLEDQIKETKELAEESTTL
A3LSG6_PICST/7-149-KINNLKADAEKWQEKSDELADRIKELEQE-----NLEKD---HQIQSLTRKNQVLEEQVEKLETDLEEIKHTADESHSL
C4R6W6_PICPG/7-149-KINKLKLDAETWQEKHDDVNSKIKVLEQE-----ALEKD---HQIQALTRKNDVLEEQVEKLEEQLSTSKETVNESHSL

PF00261

TPM3_HUMAN/49-285KKLKGTEDELDKYSEALKDAQEKLELAEKK-----AADAE---AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA
Q294A9_DROPS/48-284KKFVQVEVDLVTAKEQLEKANAELEEKEKL-----LTSTE---SEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQS
Q17H78_AEDAE/17-253KKMRQTKEEMEKYKDECEEFHKKLQGEVMR-----REEAE---SEVAALNRRIQLLEEDLERSEERLASATAKLSEASAA
TPM1_DROME/102-338KKMRQTKEEMEKYKDECEEFHKRLQLEVVR-----REEAE---SEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQA
Q6NN28_DROME/48-284KKIQTVENELDQTQEALTLVTGKLEEKNKA-----LQNAE---SEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQA
Q05705_CHICK/12-248KKIQSLQQVADEAEERAEHLQREADAERQA-----RERAE---AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA
TPM1_CIOIN/48-284KRLKATEDELDTSQEKLRTAIENLENAEKK-----AADAE---QEVASLNRRITLVEEELDRAQERLTISLSKLEEAEKA
Q676A8_OIKDI/48-282KKQKATEEELNSAKERLQKVQDELKAAEKK-----AADAE---NEVTHCNKKIMTMEEELDSVQEKLNTSIVKLDEAEKN
A7SC63_NEMVE/12-247AKLQAIKEKIDETEDRELAAMEKLREAEER-----FEKAE---GEAESFKRRIQLIEAESRRVKELSQKKDHELEEMHKR
Q6S5G5_NEMVE/6-242KKMATLRQTLEDAEARAAKAEDELKNANDR-----ADSAE---TEVAALTKQLQQLEDDLDAAESKLADTQGQLTEAEKQ
TPM_CAEBR/20-256KKMRQAREEAEAAKDEADEVKRQLEEERKK-----REDAE---AEVAALNRRIVLVEEDLERTEDRLKVATSKLEQATKA
A7RKG4_NEMVE/14-241........KIEEFEEREKAAMKKIARLEEV-----IAKDK---NESATLRRSCSLTEHQLDKTEDILDQKLERLVMLHKK
A7S0B9_NEMVE/9-244EKMQQIKDQTDDAEERELGAKSLLKEAEAK-----EEQLL---SEASGIQRRITLLNSELEKTNERVEE.QEKLLQNLVH
B7ZNL3_MOUSE/50-284..LRASEDERDRVLEELHKAEDSLLAADET-----AAKAE---ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA
C3YBA4_BRAFL/48-283KKIRMVEDELDKAQESLKDATEQLEAATKK-----AADAE---AEVASLNRRIQLVEEELDRAQERLNSTVEKLTDSEKA
E5SUX9_TRISP/48-284KKMMQVENELDKAQEELTGANAQLEEKEKK-----VQEAE---AEVAALNRRIQLLEEDFERAEERLKIATEKLEEASQT
G4VN73_SCHMA/48-283KKIQQVDTDKETAQTQLAETNTKLEETDKR-----ATEAE---AEVASLQKRIRQLEDELESTETRLQEATVKLEEASKA
H2KV99_CLOSI/48-283.RMKQAQTELDEIQEALQDSLNKMEETDKR-----ATNAE---AEVAAMTRRIRLLEEDLEVSSSRLTETLAKLDEASKT
H3CKQ9_TETNG/12-249KKIKVLQEQAEEAVERAERLQKEVEKERKA-----KEEAE---MEVCTLCNRLQNQEDVLERTQQDLEKACRQQLEFEKV
I3J233_ORENI/12-247RKIQCLQQQADDAEDRAQVLQRELDSEREL-----REKAE---GEVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA
A0A068YBH2_ECHMU/49-283.KVKNIQTEVDTVQESLQEAISKLEETEKR-----ATNAE---AEVAAMTRRIRLLEEDFEQSSGRLTETSTKLDDASKA

PF16526

E7F485_DANRE/438-508------------LEEKGRAILMKDNLIDEA.....AANAG...ADAKDLEEKVNLLGTNLDVMQTKFARLMADWTASQS-
H9GQC1_ANOCA/497-572------------LEERGRELLLKEGLFDQEAAAEDGEVGG...SEGLSVDQKLDRLQGSLETMDTRLGRLLEEHQTAQR-
F6Z6F8_ORNAN/494-563------------LEERGREILIKEGLLDES.....KATAG...TE.VTVEEKLERLESNLETLHVRFGRLLSEYTGAQQ-
F6XLL2_XENTR/582-652------------LEERGREILIKEGLLDET.....KEKIS...VKGKSSEERLELVESNLDILHTRFARLLREYSNAQQ-
H3B226_LATCH/649-719------------LEERGKEILVKEGLLDES.....AAEVG...IGEKDVEEKIERLESNLDTLQTRFARLLTEYTSTQQ-
H2LZM8_ORYLA/617-687------------LEERGREILKKEGLLDEN.....ADSGG...LQKEDTEEKVERLEMSLDTLQTRFARLLNDYTHTQQ-
Q0GFG2_DANRE/574-643------------LEEKGRQILIKEGLLEE......VEADG...IGVEDIEKRVERMEDTIEILQTRFARLLAQYTATQQ-
H0WC86_CAVPO/589-659------------LEEKGRQILMKDGLLDLD.....IANAG...SDPKDLDEKVTQMEGSLDRLQVRFARILAEYESMQQ-
F7HA92_CALJA/14-84------------LEENGKQILIKDGLLDIN.....TANAR...SEPKDFEERAIQIEGSVDLLKASSAWTLTGYESVQQ-
H0ZCV5_TAEGU/517-587------------LEEKGKQILMKDGLLDIE.....IANLG...SDPKDLEEKVAYMERAMDRLQTKFARLLAEYEGAQQ-
H3A9A8_LATCH/444-514------------LEEKGKQILMKDGLLDLE.....LASAG...ADPKDLEEKVVRMEGAIDNLQTKFARLLAGYDAAQQ-
F6SPJ8_ORNAN/520-590------------LEEKGKQILLKDGLLDLT.....VANAG...SHPKDLGEKVSRVEAAVDVLQTRFARMLAEYESMQQ-
H2MXQ7_ORYLA/551-621------------LEEKGRQILMKDGLLDLE.....VAAQG...PDPKEIEEKVDRMTSTLDALQTRYARLLAENEATQS-
E7FE78_DANRE/551-621------------LEEKGRQILMKDNLLDLE.....LAKQG...PDPKDMEEKVQKIGGVLEDLQTRFARLLAEQEAAQG-
G3Q1A1_GASAC/543-613------------LEDKGREILMRDNLIDLD.....PANIM...PETKELEENVNKLYNTMELMHFKVKKILGNNKIAEK-
I3KB24_ORENI/561-631------------LEDKGRQILMKDGLIDLD.....PANIK...PEQKELEEKVNKLYGTMELMQVKLKKILRNYENADK-
B8JHY6_DANRE/569-639------------LEEKGRQILLKDGLLELD.....PSKLK...PDERDLEDRVNRMYSTLQLMQTKVNKLLAQQEETRK-
F8W5H0_DANRE/612-682------------LEEKGKAILRKDNLLDEA.....VAAAG...ADPKDLEEKIHRLEGNLDIMTGKFAKLMAEYTSYQG-
H2N2B8_ORYLA/444-513------------LEDKGRAILMKDNLIDES.....LVAA....CDAKDLENKVNQIEASVEVMTNKFKKLTAQHQSSQR-
M4A5N4_XIPMA/513-582------------LEDKGRAILMKDNLIDES.....LVAA....VDAKDLEDKVNRIEGSVDVMTIKLRKLTNQYESSQR-
H2SR83_TAKRU/514-583------------LEEKGRSILMKDNLIDES.....LVNA....TDAKDMEVKVNQVETTLEVMTTKFRKMLNQYESSQR-
F6TBQ4_XENTR/639-709------------LEEKGRQILMKDGLIDEE.....AAKAG...ADPKDVEEKVEKMETAMDSLQTRFARLLADYNSTQL-
C3XXJ5_BRAFL/1611-1683------------LEDRGRKILMKDGLLDET.....VPNAGK.LATPRDAEDKIEKMEQSLDTLQTRFARLLAEYASTQQ-
E3LSL5_CAERE/609-676------------LLAKGREILKKDNLLDENA...P........EEQKTVEEIADHLNNAVRVLQTRMARLIVEHASTEG-
H3DY90_PRIPA/482-549------------LLLKGRELLRKDNLLDDDA...P........DEQASPEEIVDDLLQSINVLQTRVARLMAEKTSTEA-
E5SDC0_TRISP/249-316------------LINKGKEILRKDNLLDETV...E........DEQEQADRLADSFQARLQALKDRYETVIGRYEEMHR-
H2YPA8_CIOSA/10-74------------ML...K..LDKENAIDRA......EQAE...TDKKCAEDKVTEFEEELQALQKRLKATEDELDTSQE-
D6WFN2_TRICA/193-264------------LTERGCQLLRKDGLLDED....VFKKAK...ETQDSVLDSIKKLENTVEILQTRLARLLAEFSASQA-
H9ITJ7_BOMMO/375-446------------LTERGCQLLRKDGLLDEA....LFESAQ...TTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQA-
G6DLS9_DANPL/606-677------------LTERGCQLLRKDGLLDET....VFQNAQ...TTQQSLEETVHQLEATVEMLHNRLQGLLSNFGEQQA-
B4HSU3_DROSE/545-616------------LTQRGCQLLRKDGLLDEQ....IFADSQ...RVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQA-
Q7PW88_ANOGA/540-611------------LTERGCQLLRKDGLLDEA....VFANAQ...QTQDSLESGVARLEQTVENLNLRLARLLAEYSASQA-
E0VED8_PEDHC/433-504------------LMERGCQLLRKDGLLDEN....AFKKSQ...VEHETLKDKVDRLESSIENLEDKLTQLIGDVTVFHN-
G4VGD7_SCHMA/543-614------------LMQRGQDILRKDNLLDED....ILRKAQ...EQQESIEQCVQRIDNTMNQLTTRLARLIGEFGASQA-
G7YKA2_CLOSI/489-560------------LMKRGEEILRKDNLIDEE....VLRKAK...EQKESLDEYVRRLEGTVNNLSTRLARLIGEYGASQA-
K1QAP2_CRAGI/631-702------------LMDRGKLILRKDNLLDED....LMKKLE...AQQETTEQKLERIDSNLDTLQTRFARLLGDYNSTQQ-
B7QLT8_IXOSC/384-455------------LIERGRNILRRDGLLDEE....AIKVAE...EEQETLKGKCERLEKSLDHLQTRFARLLAEYMAFQV-
E9FQW8_DAPPU/491-562------------LLERGRQLLLKDGLLDEE....VNRRHQ...DESDSAKDRIEKLEMALDTLQTRFARLLAEYTSSQQ-
H2ULR0_TAKRU/439-509------------LEEKGRQILTKMGMLEEN......GDGG..EGEAATVETKIKKLESSLESLHTKLARLMAELESSNA-
G3NBT3_GASAC/462-532------------LEEKGRQILTKMGMLEES......GEHV..DEEADKLENKIGSLESKLEILQTKLARLMSELESSHR-
I3KK99_ORENI/440-510------------LEEKGRQILTKMGMLEES......GEKE..EGEGEKVEIKIKRLESNLEVLQTKLARLMMELESSNR-
H2M3C0_ORYLA/440-510------------LEEKGRQILVKMGMLDES......AEEG..DGDADQIETKLTKLEDHLELMQTKLARLMVELESSNS-
M3ZGA2_XIPMA/438-508------------LEEKGRQILIKMGMLEER......AEVE..EVEAEKVETKIERLESSLEVLRTKLARLMVELESSNR-
F1QQP5_DANRE/414-483------------LEEKGRQILTKMGMLEEA......VEGE...GEVEKTEDKVNRLEGILEMLQTKLARLIAELESSAR-
H3A5H8_LATCH/443-514------------LEEKGKAILLKMKMLDEA......AALEV.GNQEAGLEAKVQRIEKSLGSLYTSLARLVGELQSSTL-
G5BBR5_HETGA/464-535------------MEEKGREILLKMNKLDVN......AEAAE.IALQEATESRLRGLDEQLDDLQTKFARLLAELESSAL-
H9GHD3_ANOCA/465-536------------LEAKGREILLQMGQLDTQ......VEARE.EAQRREEQRRTQALQLRLDALQTRLARMLAGLESGAL-
F1N9W7_CHICK/371-442------------LEAKGREILLRMDKLDVR......AEAAA.AAAREEAEHRAQVLEAALEALQTRTARLLAQLESSAL-
F6VIY1_XENTR/441-512------------LEQKGREILLKMNKLDEQ......LADEL.AAKEQELEMKVGRLESNLDSLQTKLARLLAELESSAV-
I3KFU9_ORENI/585-652------------LEQRGRDILMKEGLLEEV.....NVSAG......EELETKVERLETSLDRFQTCLARLQSEFNSSQL-
H2SEP8_TAKRU/550-617------------LEQRGQDILQKEGLLENV.....NLSAG......DNLEEKLEKLESNLDQLQTHVARLQSEFASSQL-
A0A0K0JRY7_BRUMA/571-638------------LIAKGREILRKDGLLDED........AP...EEQMTAEEMAKNLQNTLKIMQTKMARFAAEFSSVKT-
F7CHT3_MACMU/570-639------------LEERGREILMKEGLLDEN......EVAT...SMEVDVQEKLGQLETNMETLYTRFGRLLAEYTGAQQ-
F7HCR1_MACMU/548-618------------LEEKGRQILMKDNLIDEE.....LARAG...ADPKDLEEKVEQLGSSLDTLQTRFARLLAEYNATQM-
G1KLY2_ANOCA/618-688------------LEEKGRQILMKDNLIDEE.....AAKAG...ADPRDLEEKIGKLESALDILQTRFARLLAEYTAGQA-
H3CYZ1_TETNG/446-516------------LEEKGRQILMKDGLLDLD.....PANIK...PEAKELEEKVSKLYSTMELMQIKLKKILGKHKDADK-
H3DJU6_TETNG/534-604------------LEEKGKAILMKDNLIDEA.....VANAG...ADPKDTEEKIAKLQSNLDDMQNKLAKLMAEMTSNHT-
U3INN8_ANAPL/574-644------------LEERGREILTKEGLLDES.....AAEAS...MEGKSVEEKLDRLALNLDTLHTRFGRLLTEYNDAQM-
W4XAC0_STRPU/472-545------------LEERGRTILMKDGLIDEE.....AAKRGGRTAEQVEQLEKLDRLDGNLNHLQTRFSRLLQEYSNSQM-

PF12718

C3ZKT3_BRAFL/7-153AADA--------------------------------------EAEVASLNRRIQLVEEELDRAQER--------------
E9Q454_MOUSE/7-152ATDA--------------------------------------EADVASLNRRIQLVEEELDRAQER--------------
J0DYI5_LOALO/7-152VQEA--------------------------------------EAEVAALNRRMTLLEEELERAEER--------------
Q17H75_AEDAE/7-153LQNA--------------------------------------ESEVAALNRRIQLLEEDLERSEER--------------
G4VD36_SCHMA/7-152ATNA--------------------------------------EAEVAAMTRRIRLLEEDLEVSSSR--------------
B6K811_SCHJY/7-148QSLI--------------------------------------D....SLNRKIESLEEELENSDKS--------------
A8PRF4_MALGO/7-149KSNV--------------------------------------D....ILQRRIDMLEEQLDQSERS--------------
B0CUA0_LACBS/10-152KMTS--------------------------------------E....GLQRKVQLLEEELDVAEKN--------------
Q5KF76_CRYNJ/10-149RTTG--------------------------------------E....NLARKVQLLEEELDKAEKD--------------
A1CDA8_ASPCL/16-158DTQN--------------------------------------E....ALQRRVQLLEEEAEEADRN--------------
B6HMN3_PENRW/7-149DTQN--------------------------------------E....ALQRRVQLLEEEAEENDKT--------------
C5FYF1_ARTOC/7-149SSQN--------------------------------------E....ALQRRIQLMEEEAEQTDKT--------------
A6R7T4_AJECN/7-149GTQN--------------------------------------E....SLQRRLQLLEEEAEETDKT--------------
B2B5X9_PODAN/7-149GTQN--------------------------------------E....TLTRRLQLLEEEAEQADKT--------------
B2VZI7_PYRTR/7-149GTQA--------------------------------------E....SLQRKIQVLEEEAEESDRT--------------
Q6C081_YARLI/7-149GAAN--------------------------------------E....GLSKKLAILEEDLENSDRN--------------
E7QFZ0_YEASZ/7-149RSNN--------------------------------------E....NYTKKNQDLEQQLEDSEAK--------------
A7TEE8_VANPO/7-149RSNN--------------------------------------E....NFTKKNQQLEEELEETDLK--------------
C5DUA1_ZYGRC/7-149RSNN--------------------------------------D....NYTKKNQQLEEELEESDAK--------------
B4UN77_KLULA/7-149KSHN--------------------------------------E....NFSKKNQQLEEELEENDSK--------------
Q755U4_ASHGO/7-149RSHN--------------------------------------E....NFTKKNQQLEEELEESDTK--------------
C5DMG5_LACTC/7-149RSHN--------------------------------------E....NFTKKNQQLEEELEESDTK--------------
Q6FKV5_CANGA/7-149KSHN--------------------------------------E....NFNKKNQMLEEELEETDRK--------------
A3LSG6_PICST/7-149KTSN--------------------------------------D....NYTKKNQVLEEELEEADKN--------------
C4R6W6_PICPG/7-149KTNN--------------------------------------E....NITKKNQLLEEELEAADKN--------------

PF00261

TPM3_HUMAN/49-285ADES...ERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE
Q294A9_DROPS/48-284ADEN...NRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGEAKIMELEEE
Q17H78_AEDAE/17-253ADES...ERIRKALENRTNMEDDRVAILEAQLSQAKLIAEEADKKYEEVARKLVLMEQDLERSEEKVEMNESKIVELEEE
TPM1_DROME/102-338ADES...ERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEE
Q6NN28_DROME/48-284ADES...ERIRKALENRTNMEDDKVALLENQLAQAKLIAEEADKKYEEVARKLVLMEQDLERSEEKVELSESKIVELEEE
Q05705_CHICK/12-248ADES...ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEEADRKYEEVARKLVVLEGELERSEERAEVAESRVRQLEEE
TPM1_CIOIN/48-284ADES...ERGRKVIENRSLKDEERLEVQEIQLTEAKNIAEDADRKYVEVARKLVMVEAELERGEERAELAESKAIELEEE
Q676A8_OIKDI/48-282ADES...ERGRKVIEARAAKDEERLKDQETALKEAKSVAEEADKKYEEVARKLVLVETDVEKAEERAELAETRANELEEE
A7SC63_NEMVE/12-247SKEE...ENLCKTLEVTDRESDEKMRELEDALEEAIELDKSTADKLAEVELKIKVVQGELEKAVERGDRAEMMCEHLMND
Q6S5G5_NEMVE/6-242ADES...ERARKVLENRGASDEERLASLERQYNDALERTEEAEKQYEEISERLQELENELEEAEQKADAAEARVKELEEE
TPM_CAEBR/20-256ADEA...DRARKSMETRSQQDEERANFLETQVDEAKVIAEDADRKYEEVARKLAMVEADLERAEERAEAGENKIVELEEE
A7RKG4_NEMVE/14-241TEQD...IQMLKVLEDRELEVDNSLDRLEPSAKAAIQRQHDAEMRCMEVQRRLTLTTSELHKIRARQREKEEEVRELENR
A7S0B9_NEMVE/9-244NSEM..NEEARKGLEESEMKGDEKIMDLEAKLKEMERVEKETLETLTEAERKEVVVTRDLERAIEKGRTLENRIQSLEST
B7ZNL3_MOUSE/50-284ADES...ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEE
C3YBA4_BRAFL/48-283ADES...ERARKVLENRGAADEDRMELLDMQLREAKMIAEEADRKYEEVARKLVITEGDLERAEERADLAETKAAELEEE
E5SUX9_TRISP/48-284ADES...ERVRKVMENRSLQDEERVYQLEAQLKEAQLLAEEADRKYDEVARKLAMVEADLERAEERAEAGENKIVELEEE
G4VN73_SCHMA/48-283ADES...DRGRKVLENRTFADEERINQLEEQLKESTFMAEDADRKYDEATRKLAVAEVALSHAEDRIEAAESKITELEEE
H2KV99_CLOSI/48-283AEES...ERGRKELEIRSIADDERLSQLEDQQKEAKYIAEDADRKYDEAARKLAIVEVDFERAESRLEAAESKIVELEEE
H3CKQ9_TETNG/12-249ADERQRPHRGMKVIENRAQKDEEKLEFLEAQLNEAKGIADEADRKYEESARRVKCLEDDLERAEDKAAKSLSKCCVLEEE
I3J233_ORENI/12-247ADES...ERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAELSECKASDLEEE
A0A068YBH2_ECHMU/49-283AEES...ERNRKTLETRSISDDERMAQLEEQVKEAKYIAEDAERKYDEAARRLAVTEVDLERAESRLETSESKIVELEEE

PF16526

E7F485_DANRE/438-508-----------------------------------------------RIKQRLTNMEAR---------------------
H9GQC1_ANOCA/497-572-----------------------------------------------KLKRRVAALEAR---------------------
F6Z6F8_ORNAN/494-563-----------------------------------------------RLKQRITVLENR---------------------
F6XLL2_XENTR/582-652-----------------------------------------------TLKQRVTLLELK---------------------
H3B226_LATCH/649-719-----------------------------------------------KLKQRITNLEAK---------------------
H2LZM8_ORYLA/617-687-----------------------------------------------RLKQRVTLLEQQ---------------------
Q0GFG2_DANRE/574-643-----------------------------------------------HLKQRLTTLECR---------------------
H0WC86_CAVPO/589-659-----------------------------------------------KLKQRLTKVEKF---------------------
F7HA92_CALJA/14-84-----------------------------------------------KLKQRFTKAEKY---------------------
H0ZCV5_TAEGU/517-587-----------------------------------------------KVKKRLTQIEKI---------------------
H3A9A8_LATCH/444-514-----------------------------------------------KLKQRVTKIEKK---------------------
F6SPJ8_ORNAN/520-590-----------------------------------------------KLKRRLAKVEES---------------------
H2MXQ7_ORYLA/551-621-----------------------------------------------KIKHRVTRLERK---------------------
E7FE78_DANRE/551-621-----------------------------------------------KLKKRVTKLEKK---------------------
G3Q1A1_GASAC/543-613-----------------------------------------------ALRRRIADLEHL---------------------
I3KB24_ORENI/561-631-----------------------------------------------TLKHRIIDLERF---------------------
B8JHY6_DANRE/569-639-----------------------------------------------SIRRRIIEIERF---------------------
F8W5H0_DANRE/612-682-----------------------------------------------KIKQRITNMENK---------------------
H2N2B8_ORYLA/444-513-----------------------------------------------KLKQRLSNLSNQ---------------------
M4A5N4_XIPMA/513-582-----------------------------------------------KLNQRLANLSNE---------------------
H2SR83_TAKRU/514-583-----------------------------------------------KLKQRLSNLSNE---------------------
F6TBQ4_XENTR/639-709-----------------------------------------------KLKQRVTKLESQ---------------------
C3XXJ5_BRAFL/1611-1683-----------------------------------------------KLKKRLTKLEQG---------------------
E3LSL5_CAERE/609-676-----------------------------------------------KLMKRIEQLEKN---------------------
H3DY90_PRIPA/482-549-----------------------------------------------KLNTRIEILERE---------------------
E5SDC0_TRISP/249-316-----------------------------------------------RMNRRIAFLESK---------------------
H2YPA8_CIOSA/10-74-----------------------------------------------KLRSAIEDLEKA---------------------
D6WFN2_TRICA/193-264-----------------------------------------------KLKQRLTRLELS---------------------
H9ITJ7_BOMMO/375-446-----------------------------------------------EMKQRMNNIEVR---------------------
G6DLS9_DANPL/606-677-----------------------------------------------KLKQRLNKVELR---------------------
B4HSU3_DROSE/545-616-----------------------------------------------KIKQRLAKLEMN---------------------
Q7PW88_ANOGA/540-611-----------------------------------------------KLKQRISKLEDR---------------------
E0VED8_PEDHC/433-504-----------------------------------------------RMKRRASKIEQK---------------------
G4VGD7_SCHMA/543-614-----------------------------------------------KLKRRLTRLEQE---------------------
G7YKA2_CLOSI/489-560-----------------------------------------------KLKRRITQLEEY---------------------
K1QAP2_CRAGI/631-702-----------------------------------------------KLKQRITKLEKL---------------------
B7QLT8_IXOSC/384-455-----------------------------------------------KMKQRITKLEGN---------------------
E9FQW8_DAPPU/491-562-----------------------------------------------TMKQRLSRVEQH---------------------
H2ULR0_TAKRU/439-509-----------------------------------------------KMQVRVEQLEWE---------------------
G3NBT3_GASAC/462-532-----------------------------------------------KMQARVEQLEWE---------------------
I3KK99_ORENI/440-510-----------------------------------------------KMQARVAQLELE---------------------
H2M3C0_ORYLA/440-510-----------------------------------------------KMQARVERLEWE---------------------
M3ZGA2_XIPMA/438-508-----------------------------------------------KMRARVEQLEMR---------------------
F1QQP5_DANRE/414-483-----------------------------------------------KMMQRVDQLELQ---------------------
H3A5H8_LATCH/443-514-----------------------------------------------KLRYRIKLLEEE---------------------
G5BBR5_HETGA/464-535-----------------------------------------------KIAYRIERLEWQ---------------------
H9GHD3_ANOCA/465-536-----------------------------------------------KLTLRLERLEGG---------------------
F1N9W7_CHICK/371-442-----------------------------------------------KLALRIGSLESR---------------------
F6VIY1_XENTR/441-512-----------------------------------------------KMTQRIRQLEWE---------------------
I3KFU9_ORENI/585-652-----------------------------------------------RLKQRITALESN---------------------
H2SEP8_TAKRU/550-617-----------------------------------------------QLKQRITILENP---------------------
A0A0K0JRY7_BRUMA/571-638-----------------------------------------------KLLARIEYLETQ---------------------
F7CHT3_MACMU/570-639-----------------------------------------------KLKQRITILETK---------------------
F7HCR1_MACMU/548-618-----------------------------------------------KMKQRLSQLESQ---------------------
G1KLY2_ANOCA/618-688-----------------------------------------------KVKQRLVKVETK---------------------
H3CYZ1_TETNG/446-516-----------------------------------------------VLKQRIADLERR---------------------
H3DJU6_TETNG/534-604-----------------------------------------------RIKQRVTQMEAK---------------------
U3INN8_ANAPL/574-644-----------------------------------------------KLKQRITVLESQ---------------------
W4XAC0_STRPU/472-545-----------------------------------------------KLKQRLTRLEKK---------------------

PF12718

C3ZKT3_BRAFL/7-153----------------------------LNSTVEKLTDSEKAADESERARKVLENRGAADEDRMELLDMQLREAKM----
E9Q454_MOUSE/7-152----------------------------LATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAK.----
J0DYI5_LOALO/7-152----------------------------LKIATDKLEEATHTADESERVRKVMENRSFQDEERANTVESQLKEAQ.----
Q17H75_AEDAE/7-153----------------------------LASATAKLSEASAAADESERARKVLENRALADEERMDALENQLKEARF----
G4VD36_SCHMA/7-152----------------------------LTETLTKLEEASKTAEESERGRKDLEIRSIADDERLNQLEDQQKEAK.----
B6K811_SCHJY/7-148----------------------------LRETTEKLRQIDINTEHTERKIQALEHERDDLEVRLEDTTDKYNKVK.----
A8PRF4_MALGO/7-149----------------------------LKETTEQLRHTDVRAEQLERQIQGAEQERDQWEHKYEEAQERYQASKR----
B0CUA0_LACBS/10-152----------------------------VKETVERLRQVDVKAEHFERQVQRLEQERDLWEKKYEESEAKYKKSQA----
Q5KF76_CRYNJ/10-149----------------------------LKETTEKLRQVDVKAEHFERQVQRLEQERDEWERKHGEAVEKYQQSKR----
A1CDA8_ASPCL/16-158----------------------------LRETNEKLRQTDVKAGHYERKVQALEASRDQWESKYEEMAKKYAELQK----
B6HMN3_PENRW/7-149----------------------------LRETNEKLRQTDIKAGHYERKVQALEDQHAKLEQRYEDAIKEHSAVKK----
C5FYF1_ARTOC/7-149----------------------------LRETNEKLRQTDVKAGHFERKVQALEATREQWETKYEEMSKQYAAVKE----
A6R7T4_AJECN/7-149----------------------------LRETNEKLRQTDVKAGHYERKVQALETSRDQWEAKYEQMSKKYEDLQK----
B2B5X9_PODAN/7-149----------------------------LREANEKLRQTDVKAGHFERKVQALEQERDQWESKYEEMAKKYATVQK----
B2VZI7_PYRTR/7-149----------------------------IRELNEKLRQTDVKSGHYERKVQALEQSRDQWETKYEEMAKKYADTKK----
Q6C081_YARLI/7-149----------------------------LRETTEKLRQTDVKAEHFERKVTSLEQERDDWEKKHEELLEKYNAAKK----
E7QFZ0_YEASZ/7-149----------------------------LKEAMDKLKEADLNSEQMGRRIVALEEERDEWEKKCEEFQSKYEEAQK----
A7TEE8_VANPO/7-149----------------------------LKETIEKLRESDLKSETLERKVNALEDERNDWEKKYEDLSVQYETAKK----
C5DUA1_ZYGRC/7-149----------------------------LKETTEKLRETDLKAEQLERKVVALEEERDEWERKHEELTSKYEEAKK----
B4UN77_KLULA/7-149----------------------------LKETTEKLREADLKVEQLERKVTSLEQERDDLEKKYDDLQTKYDAAKA----
Q755U4_ASHGO/7-149----------------------------LKETLELLRETDLKSEQLERKVASLENEVQDWESKYEELQTKYSSAKG----
C5DMG5_LACTC/7-149----------------------------LKETTDKLRETDLKAEGLERKVVSLEQERDDWEKKYEELTAKYDEAKK----
Q6FKV5_CANGA/7-149----------------------------LKETSDRLKEIELNSETLERKTAALQEERDEWEKKYEEVAAKYEDAKK----
A3LSG6_PICST/7-149----------------------------LKETTEKLRETDIKAEQLERKVASLEQEKEEWERKYEELTEQHLAAKS----
C4R6W6_PICPG/7-149----------------------------LKETTEKLRDTDIKAEALEKKVTSLENEREEWERKFEELQEKYNATRE----

PF00261

TPM3_HUMAN/49-285LKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDH
Q294A9_DROPS/48-284LKVVGNSLKSLEVSEEKANQRVEEFKREMKTLAIKLKEAEQRAEHAEKQVKRLQKEVDRLEDRLFNEKEKYKAICDDLDQ
Q17H78_AEDAE/17-253LRVVGNNLKSLEVSEEKAMASRDSVEDKIHQLNDKLTNAEARAEFAERSVQKLQKEVDRLEEEVTKEKSKYKAIAAELDL
TPM1_DROME/102-338LRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDLDT
Q6NN28_DROME/48-284LRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDLDT
Q05705_CHICK/12-248LRTMDQSLKSLIASEEEYSTKEDKYEEEIKLLGEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDN
TPM1_CIOIN/48-284LKIVANNLKSLEASAEKYAAKEGIFEEEIKTLSDKLKDSETRAEFAEKSVVKLEKNIDELEDSLYAEKCKIKAISEDMDV
Q676A8_OIKDI/48-282LKAVANNLKSLEAAAEKYTTKEAQYIEEVRSLEEKLKDAGERADHAEKSVTELESTIDELEDKLYAEKLKIKQTVEDMDN
A7SC63_NEMVE/12-247FTGTSEVLRDLEVKDAAASEREIDNEDKIEFIQENLKQMVYRYEEAERKAPPLEMLLDQLVEDLELYRLKRKQVDEEM.K
Q6S5G5_NEMVE/6-242VTLVGNNLRSLEISEGKASEREDTYENQIRELETKLQDAEERAEKAEQKVQELEAQAEAMEAELEKAKEQYEKVKEELDS
TPM_CAEBR/20-256LRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELLLEKERVRNLTEEIEQ
A7RKG4_NEMVE/14-241LKVGGRSIQQLVISEEKYCDKEDEFRHRIRLLKANLAATILRAEESERRCMRLERENDMVEEETRAYKKNYDMMQKELHD
A7S0B9_NEMVE/9-244MGNALTNIQKLEASGDEAYEREELKEEKLKFFQEQLKQYEQRYEDAEREALKLERINDTIIIEIDSYKKKKEEILREMDL
B7ZNL3_MOUSE/50-284LKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ
C3YBA4_BRAFL/48-283LKNVTNQLKSLEAAADKASEKEEAYEEQVRDLSAKLKEAETRAEFAERTVAKLEKNVDDLEDELYAEKLKFKGISEELDH
E5SUX9_TRISP/48-284LRVVGNNLKSLEVSEEKALQREDSYEEQIRLLTQRLKEAETRAEFAERSVQKLQKEVDRLEDELVHEKEKYKAISEELDQ
G4VN73_SCHMA/48-283LRIVGNNVKSLEISEQEAAQREEAYEENIRDLTERLKAAEDRAQESERLVNTLQADADRLEDELVTEKEKYKALSEELDS
H2KV99_CLOSI/48-283LRVVGNNMKALEISEQESAQREESYEETIRDLTERLKAAEQRAAEAERQVSKLQNEVDHLEDDLLAEKIRYKDLSGELDQ
H3CKQ9_TETNG/12-249LKTIIATSRSLEAQVEKYSVKEDKYELAIRNLTDKLKEAENRAEAAERTLSTCERTISSLEDALGEAREENTKITATLDQ
I3J233_ORENI/12-247LKNVTNNLKSLEAQSEKYSEKEDKYEEEIKVLTDKLKEAETRAEFAERTVAKLEKSIDDLEEKLSHAKEENLGMHQVLDQ
A0A068YBH2_ECHMU/49-283LRIVGNNMKSLEVSEQESLQREESYEETIRDLTERLKTAEQRAAEAERQVSKLQNEVDRLEDELLSEKERYRAISGELDT

PF16526

E7F485_DANRE/438-508--------------------------------------------------------------------------------
H9GQC1_ANOCA/497-572--------------------------------------------------------------------------------
F6Z6F8_ORNAN/494-563--------------------------------------------------------------------------------
F6XLL2_XENTR/582-652--------------------------------------------------------------------------------
H3B226_LATCH/649-719--------------------------------------------------------------------------------
H2LZM8_ORYLA/617-687--------------------------------------------------------------------------------
Q0GFG2_DANRE/574-643--------------------------------------------------------------------------------
H0WC86_CAVPO/589-659--------------------------------------------------------------------------------
F7HA92_CALJA/14-84--------------------------------------------------------------------------------
H0ZCV5_TAEGU/517-587--------------------------------------------------------------------------------
H3A9A8_LATCH/444-514--------------------------------------------------------------------------------
F6SPJ8_ORNAN/520-590--------------------------------------------------------------------------------
H2MXQ7_ORYLA/551-621--------------------------------------------------------------------------------
E7FE78_DANRE/551-621--------------------------------------------------------------------------------
G3Q1A1_GASAC/543-613--------------------------------------------------------------------------------
I3KB24_ORENI/561-631--------------------------------------------------------------------------------
B8JHY6_DANRE/569-639--------------------------------------------------------------------------------
F8W5H0_DANRE/612-682--------------------------------------------------------------------------------
H2N2B8_ORYLA/444-513--------------------------------------------------------------------------------
M4A5N4_XIPMA/513-582--------------------------------------------------------------------------------
H2SR83_TAKRU/514-583--------------------------------------------------------------------------------
F6TBQ4_XENTR/639-709--------------------------------------------------------------------------------
C3XXJ5_BRAFL/1611-1683--------------------------------------------------------------------------------
E3LSL5_CAERE/609-676--------------------------------------------------------------------------------
H3DY90_PRIPA/482-549--------------------------------------------------------------------------------
E5SDC0_TRISP/249-316--------------------------------------------------------------------------------
H2YPA8_CIOSA/10-74--------------------------------------------------------------------------------
D6WFN2_TRICA/193-264--------------------------------------------------------------------------------
H9ITJ7_BOMMO/375-446--------------------------------------------------------------------------------
G6DLS9_DANPL/606-677--------------------------------------------------------------------------------
B4HSU3_DROSE/545-616--------------------------------------------------------------------------------
Q7PW88_ANOGA/540-611--------------------------------------------------------------------------------
E0VED8_PEDHC/433-504--------------------------------------------------------------------------------
G4VGD7_SCHMA/543-614--------------------------------------------------------------------------------
G7YKA2_CLOSI/489-560--------------------------------------------------------------------------------
K1QAP2_CRAGI/631-702--------------------------------------------------------------------------------
B7QLT8_IXOSC/384-455--------------------------------------------------------------------------------
E9FQW8_DAPPU/491-562--------------------------------------------------------------------------------
H2ULR0_TAKRU/439-509--------------------------------------------------------------------------------
G3NBT3_GASAC/462-532--------------------------------------------------------------------------------
I3KK99_ORENI/440-510--------------------------------------------------------------------------------
H2M3C0_ORYLA/440-510--------------------------------------------------------------------------------
M3ZGA2_XIPMA/438-508--------------------------------------------------------------------------------
F1QQP5_DANRE/414-483--------------------------------------------------------------------------------
H3A5H8_LATCH/443-514--------------------------------------------------------------------------------
G5BBR5_HETGA/464-535--------------------------------------------------------------------------------
H9GHD3_ANOCA/465-536--------------------------------------------------------------------------------
F1N9W7_CHICK/371-442--------------------------------------------------------------------------------
F6VIY1_XENTR/441-512--------------------------------------------------------------------------------
I3KFU9_ORENI/585-652--------------------------------------------------------------------------------
H2SEP8_TAKRU/550-617--------------------------------------------------------------------------------
A0A0K0JRY7_BRUMA/571-638--------------------------------------------------------------------------------
F7CHT3_MACMU/570-639--------------------------------------------------------------------------------
F7HCR1_MACMU/548-618--------------------------------------------------------------------------------
G1KLY2_ANOCA/618-688--------------------------------------------------------------------------------
H3CYZ1_TETNG/446-516--------------------------------------------------------------------------------
H3DJU6_TETNG/534-604--------------------------------------------------------------------------------
U3INN8_ANAPL/574-644--------------------------------------------------------------------------------
W4XAC0_STRPU/472-545--------------------------------------------------------------------------------

PF12718

C3ZKT3_BRAFL/7-153--------
E9Q454_MOUSE/7-152--------
J0DYI5_LOALO/7-152--------
Q17H75_AEDAE/7-153--------
G4VD36_SCHMA/7-152--------
B6K811_SCHJY/7-148--------
A8PRF4_MALGO/7-149--------
B0CUA0_LACBS/10-152--------
Q5KF76_CRYNJ/10-149--------
A1CDA8_ASPCL/16-158--------
B6HMN3_PENRW/7-149--------
C5FYF1_ARTOC/7-149--------
A6R7T4_AJECN/7-149--------
B2B5X9_PODAN/7-149--------
B2VZI7_PYRTR/7-149--------
Q6C081_YARLI/7-149--------
E7QFZ0_YEASZ/7-149--------
A7TEE8_VANPO/7-149--------
C5DUA1_ZYGRC/7-149--------
B4UN77_KLULA/7-149--------
Q755U4_ASHGO/7-149--------
C5DMG5_LACTC/7-149--------
Q6FKV5_CANGA/7-149--------
A3LSG6_PICST/7-149--------
C4R6W6_PICPG/7-149--------

PF00261

TPM3_HUMAN/49-285ALNDMTSI
Q294A9_DROPS/48-284TFAELTGY
Q17H78_AEDAE/17-253TFADLSGY
TPM1_DROME/102-338AFVELILK
Q6NN28_DROME/48-284AFVELILK
Q05705_CHICK/12-248ALNDITSL
TPM1_CIOIN/48-284TLQGIGDL
Q676A8_OIKDI/48-282TIH..ASA
A7SC63_NEMVE/12-247AMGELVEQ
Q6S5G5_NEMVE/6-242TLAELSEM
TPM_CAEBR/20-256TVQEIQGS
A7RKG4_NEMVE/14-241TLNDIEC.
A7S0B9_NEMVE/9-244ELVDLNR.
B7ZNL3_MOUSE/50-284TLLELNNM
C3YBA4_BRAFL/48-283TLNDLST.
E5SUX9_TRISP/48-284TFQELSGY
G4VN73_SCHMA/48-283TFAELTG.
H2KV99_CLOSI/48-283TFAELTGY
H3CKQ9_TETNG/12-249TLHDLN..
I3J233_ORENI/12-247TLQELNS.
A0A068YBH2_ECHMU/49-283TFAELTS.

PF16526

E7F485_DANRE/438-508--------
H9GQC1_ANOCA/497-572--------
F6Z6F8_ORNAN/494-563--------
F6XLL2_XENTR/582-652--------
H3B226_LATCH/649-719--------
H2LZM8_ORYLA/617-687--------
Q0GFG2_DANRE/574-643--------
H0WC86_CAVPO/589-659--------
F7HA92_CALJA/14-84--------
H0ZCV5_TAEGU/517-587--------
H3A9A8_LATCH/444-514--------
F6SPJ8_ORNAN/520-590--------
H2MXQ7_ORYLA/551-621--------
E7FE78_DANRE/551-621--------
G3Q1A1_GASAC/543-613--------
I3KB24_ORENI/561-631--------
B8JHY6_DANRE/569-639--------
F8W5H0_DANRE/612-682--------
H2N2B8_ORYLA/444-513--------
M4A5N4_XIPMA/513-582--------
H2SR83_TAKRU/514-583--------
F6TBQ4_XENTR/639-709--------
C3XXJ5_BRAFL/1611-1683--------
E3LSL5_CAERE/609-676--------
H3DY90_PRIPA/482-549--------
E5SDC0_TRISP/249-316--------
H2YPA8_CIOSA/10-74--------
D6WFN2_TRICA/193-264--------
H9ITJ7_BOMMO/375-446--------
G6DLS9_DANPL/606-677--------
B4HSU3_DROSE/545-616--------
Q7PW88_ANOGA/540-611--------
E0VED8_PEDHC/433-504--------
G4VGD7_SCHMA/543-614--------
G7YKA2_CLOSI/489-560--------
K1QAP2_CRAGI/631-702--------
B7QLT8_IXOSC/384-455--------
E9FQW8_DAPPU/491-562--------
H2ULR0_TAKRU/439-509--------
G3NBT3_GASAC/462-532--------
I3KK99_ORENI/440-510--------
H2M3C0_ORYLA/440-510--------
M3ZGA2_XIPMA/438-508--------
F1QQP5_DANRE/414-483--------
H3A5H8_LATCH/443-514--------
G5BBR5_HETGA/464-535--------
H9GHD3_ANOCA/465-536--------
F1N9W7_CHICK/371-442--------
F6VIY1_XENTR/441-512--------
I3KFU9_ORENI/585-652--------
H2SEP8_TAKRU/550-617--------
A0A0K0JRY7_BRUMA/571-638--------
F7CHT3_MACMU/570-639--------
F7HCR1_MACMU/548-618--------
G1KLY2_ANOCA/618-688--------
H3CYZ1_TETNG/446-516--------
H3DJU6_TETNG/534-604--------
U3INN8_ANAPL/574-644--------
W4XAC0_STRPU/472-545--------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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