Sequence alignment for CL0459

PF12738

ECT2_MOUSE/179-242--------LVLCF-------TGFRKKE...ELVKL---VTLVHHMGGVI-------------------------RKEC.N
A1CWA7_NEOFI/345-407--------LKISL-------SNYVGEA....RIYL---ENLIAAAGAEC-------------------------TKTL.K
A2R3M9_ASPNC/121-184--------LSICI-------TGFEDMS...LRNRI---QDTVTAHGAEF-------------------------RKDL.T
A5B5A0_VITVI/458-520--------IIATV-------SGYHGVE....RSNL---IKLISQTGAKY-------------------------VGTM.S
A7F1C2_SCLS1/119-182--------LRISL-------TGCDDTA...ERQDI---AEKIKANGGEY-------------------------DGNL.T
A7S5M3_NEMVE/449-511--------MSISV-------TGFTGQE....RQLV---RNMVFMIGANY-------------------------TGYL.M
A9PDJ1_POPTR/4-66--------VVATV-------SGYHGSE....RFNL---IKLISQSGASY-------------------------VGAM.S
A9RB53_PHYPA/468-530--------VKFCV-------SQYSERD....RKLL---RKLCYVLKVKF-------------------------SETL.N
B0DMV8_LACBS/502-564--------VRMSL-------SGLDEAD....AHGI---KRLMRAIGLVI-------------------------PPVF.S
B2VU23_PYRTR/350-412--------YKISI-------SSYTGEA....RVYL---ENLIKASGAEF-------------------------TKTF.K
B2W796_PYRTR/229-291--------ITITP-------GHMPASL....RESL---QRSVERIGAKI-------------------------SDNV.R
B2W7P6_PYRTR/114-177--------LKICL-------TGFDNPD...QRKSI---QDKVDANGGEY-------------------------HGDL.T
B3NSB0_DROER/190-254--------IVVYV-------EVRTGNDN..RSEGV---KTIIAKMGAQV-------------------------KDRL.T
B3RL44_TRIAD/702-764--------MVIAV-------TGYTGKE....RDKV---KMIINAIGANY-------------------------TPHL.S
B4DWW2_HUMAN/9-75--------VVAYV-------EVWSSNGTENYSKTF---TTQLVDMGAKV-------------------------SKTF.N
B4H593_DROPE/186-250--------VVVYV-------DVRSGNDN..RSDGV---KSIIADMGAQI-------------------------NDRL.L
B4KSD3_DROMO/76-140--------VIVYV-------EVRTGNDN..RSEGV---KNIITKLGAQA-------------------------NDRL.L
B5FXA4_TAEGU/27-93--------ISAFV-------EVWSSSRTENYSKTF---EQQLLDMGAEV-------------------------SKTL.N
B6HL54_PENCW/128-191--------LKICI-------TGFSDLP...FRAYM---QKTTEENGAEY-------------------------RKDL.T
B6Q6C3_PENMQ/111-174--------LSICV-------TGFEDPS...YRTYL---QETTIANGAEF-------------------------RKDL.T
TOB1A_XENLA/202-265--------CTICV-------TGLSSLD....RKEV---QRLTALHGGEY-------------------------TGQLKM
B8BJJ5_ORYSI/208-271--------LNICI-------TKLNVDE....RREL---AKIIVQNGGQY-------------------------SANL.T
B8LKV4_PICSI/41-103--------VVVSI-------SGYSVLE....KIKL---TKLIDQTGALY-------------------------TGSL.G
B9GSH3_POPTR/111-175--------ITMCL-------TGYQRQD....RDDI---MTMVGLMGAHF-------------------------SKPLVA
C0NFA4_AJECG/121-184--------LSICL-------TGFDDMN...HRNSL---QKLITENGAEF-------------------------RRDL.T
C1FFW2_MICSR/561-624--------LRIST-------SLYDEDV....KSSV---NMLCHLLGAKY-------------------------TERLGR
C1GTX0_PARBA/624-691--------VVLVF-------SGVLPLGTDMQSADI---SMWAKSFGATI-------------------------SHKI.N
C4M4C9_ENTHI/17-80--------YVICV-------SGYSTDE....RVLL---GGMIEQFGGIY-------------------------MEDMES
C5FMN4_ARTOC/111-174--------LSICI-------TGFENTD...FRSHL---EKTVSENGGEF-------------------------RKDL.T
MU176_SCHPO/179-233--------I....-------..............V---TEQLRLLGATV-------------------------HASLQM
RAD4_SCHPO/105-167--------CRVCL-------TNIGQPE....RSRI---ENYVLKHGGTF-------------------------CPDL.T
Q014F9_OSTTA/116-179--------ARIVV-------DGYVGQD....KLDL---VELIEAAGGTH-------------------------EEEM.T
Q0UDZ8_PHANO/130-193--------LKICL-------TGFDNPE...QRRYI---QETVDKNGAEY-------------------------HGDL.T
Q16W28_AEDAE/219-283--------VCIYV-------EVRSGTDN..RSDGI---RDHLVSLGAKV-------------------------NDKL.Y
Q1K5Z2_NEUCR/339-401--------MKITL-------SNYGGDA....RVYL---ENLITAAGATY-------------------------TKTM.K
Q2H787_CHAGB/324-387--------LLCCM-------TGFEDPD...EREQI---IGQIEANGGLY-------------------------TGDL.T
Q2R9I2_ORYSJ/195-257--------FRFCV-------SQYEEKD....RLLL---KNLCFILGSKF-------------------------TEKA.T
Q4CP92_TRYCC/1-63--------MLVTT-------TAIYGEE....LDRI---KKDLHQQGVTY-------------------------VAEL.T
Q4PHX3_USTMA/599-667--------LRLML-------LGFDPDSP..ELYHA---QKLVVEMGGSI-------------------------ITHWKA
Q4T8H9_TETNG/716-778--------HIMSV-------TGFVDAD....RDDL---KLMAYLTGARY-------------------------TGYL.C
Q55XE8_CRYNB/497-562--------IIVHI-------SGSEDHQ...LSSYH---RRLARALGKCF-------------------------ELQLTV
Q5TRD6_ANOGA/110-173--------VITCF-------TGIRKKD...ELTHL---VHLIHSMGGSI-------------------------RKGM.D
Q6CN34_KLULA/351-414--------LKATY-------TNYYGEQ....RYYI---QLLVEALGGIC-------------------------STEL.T
PAXI1_MOUSE/102-165--------LTACL-------SQVSSED....RSAL---WALVTFHGGSC-------------------------QLNL.N
Q6Z553_ORYSJ/10-72--------VVATV-------SGYHGDE....RHRL---VRLIAETGASY-------------------------VGAM.S
Q70X85_ARATH/188-251--------LTICV-------TRIPADE....RKGM---EKVISEYGGSY-------------------------SAEL.T
Q98SN2_XENLA/642-715--------VIISF-------SGLHPTNFPIERTRE---FYHARALGASI-------------------------HKNLIL
Q9FVX6_ARATH/479-541--------LCICS-------SQHNEKN....VELL---RNLSVVLGADF-------------------------VERL.T
Q9U7D8_DROME/117-180--------VVTCF-------TGIRKKD...ELTKL---VNLIHSMGGCI-------------------------KKDL.N

PF00533

Y4211_ARATH/1089-1168VFQDQEHEPKFFI.......VSGPRSQ----RNEY...QQIIRRLKGKCC......................RDSHQW.S
MDB1_SCHPO/384-455NKHTNLVTSSFNL..............----TKPM...KSFIRRNGLRV.........................QESV.T
MDB1_SCHPO/485-573HRRTCFNGKRLYIT.....KAIRDSMV----GDSIHGLYSILETSGAEIV......................GDIKRA.Q
DNLI3_MOUSE/939-1006VLLDVFTGVRLYL........PPSTPD----FKRL...KRYFVAFDGDL........................VQEFD.M
ECT2_MOUSE/266-341FKVPPFQDCILSF.......LGFSDEE----KHSM...EEMTEMQGGSY.........................LPVG.D
PAXI1_HUMAN/701-776PGGKPCSQHIISV.......TGFVDSD----RDDL...KLMAYLAGAKY.........................TGYL.C
PAXI1_HUMAN/860-934KLTPELTPFVLFT........GFEPVQ----VQQY...IKKLYILGGEV..........................AES.A
TDT_HUMAN/27-111PQDIKFQDLVVFIL.....EKKMGTTR----RAFL...MELARRKGFRV.........................ENEL.S
RAD9_YEAST/994-1109RTGNVFDKCIFVL........TSLFEN----REEL...RQTIESQGGTVIESGFSTLFNF..THPLAKSLVNKGNTDN.I
XRCC1_HUMAN/538-616ELPDFFQGKHFFL......YGEFPGDE----RRKL...IRYVTAFNGEL.........................EDNM.S
Q93161_CAEEL/981-1063NVPQKFPTTSFHI..........WIDE----RTDINITNQFMEKFQAIT.........................SDEA.N
PARP4_HUMAN/1-81MVMGIFANCIFCLK.....VKYLPQQQ----KKKL...QTDIKENGGKF.........................SFSL.N
TOPB1_HUMAN/101-176VYNMVMSDVTISC.......TSLEKEK----REEV...HKYVQMMGGRV.........................YRDL.N
TOPB1_HUMAN/195-271FKCPIFLGCIICV.......TGLCGLD----RKEV...QQLTVKHGGQY.........................MGQLKM
TOPB1_HUMAN/354-431APEDLLDGCRIYL.......CGFSGRK----LDKL...RRLINSGGGVR.........................FNQL.N
TOPB1_HUMAN/548-620TEEGLFSQKSFLV.......LGFSNEN----ESNI...ANIIKENAGKI.........................MSLL.S
TOPB1_HUMAN/641-725TGMTPLEDCVISF.......SQCAGAE----KESL...TFLANLLGASVQEYF................VRKSNAKKG.M
TOPB1_HUMAN/900-978EAPKPLHKVVVCV.......SKKLSKK----QSEL...NGIAASLGADY.........................RWSF.D
TOPB1_HUMAN/1260-1338THEELKKQYIFQL.......SSLNPQE----RIDY...CHLIEKLGGLVI.......................EKQCF.D
Q20129_CAEEL/451-529GLGDLFENCMFYI.......CGVDESR----MEKW...RRFLNETGATR.........................VAKF.T
Q20129_CAEEL/587-659TQVGIFSYHTYCV......HCSVDQEV----SDDL...KEKIPLNGGKL.........................MDDP.D
Q20129_CAEEL/679-749PPILIFNQRGFQL.......KCKDPFL----RDRV...RDIIEDNGGRI.........................VEQL.E
DNLJ_HAEIN/592-668ASENLFKDKTVVL......TGTLTQMG----RNEA...KALLQQLGAKV.........................SGSV.S
DNLI4_CANAL/673-756VESDLFSGIEFLIM....SDKREADGE----VTTIEEMKAMVKQYGGKI.........................VNSV.D
PESC_DANRE/323-403KQKKLFEGLKFFL.........NREVP----RESL...AFVIRCFGGEVSWDKS..............LCIGSTYEAT.D
Q20129_CAEEL/128-204VYSSVFQDVKISF.......TGLNLTK----KQEL...YEKIGWMCGVV.........................GDAL.Y
O76369_CAEEL/929-1023GKNALLDAIREVN........KTNVMK----ALKMGSYINAYNKHGNTALHVAV...............RKAHTSDEQ.M
PAXI1_MOUSE/8-80VPEELFREVKYYA..............----VGDIDPQVIQLLKAGKAK.........................EVSY.N
PAXI1_MOUSE/94-170ESCQIFFGLTACL.......SQVSSED----RSAL...WALVTFHGGSC.........................QLNL.N
PAXI1_MOUSE/588-668PEESFLLGCVFAIA.....DYPEQMSD----KQLLATWKRIIQAHGGTV.........................DPTF.T
PARP1_MOUSE/385-463PADKPLSNMKILT.......LGKLSQN----KDEA...KAVIEKLGGKL.........................TGSA.N
DNLI4_HUMAN/654-730KISNIFEDVEFCV......MSGTDSQP----KPDL...ENRIAEFGGYI.........................VQNP.G
DNLI4_HUMAN/814-898RRHTVYLDSYAVIN....DLSTKNEGT----RLAIKALE..LRFHGAKV.........................VSCL.A
TDT_AMBME/27-111KYDIKFKDIAIYIL.....ERKMGASR----RYFL...MELARKKGFRV.........................EPDL.S
O16568_CAEEL/1044-1144MRPKLLEQCGFHI.........LETEL----LKNREGWEEVIKLFGGSV.........................VQDI.E
PESC_HUMAN/322-402KHKKLFEGLKFFL.........NREVP----REAL...AFIIRSFGGEVSWDKS..............LCIGATYDVT.D
TDT_MONDO/27-111IYEIKFHEFVLFIL.....EKKMGATR----RTFL...TDLARKKGFRV.........................ENEL.S
O16229_CAEEL/378-460NVPQQFPVSSFHI..........WMDE----KTDDKLTNAFMEKFPSIT.........................SDEA.M
DNLJ_HELPY/577-652KSSSVFNNKTIVL......TGTLSK.P----RQEY...AQMLENLGAKI.........................SSSV.S
DNLJ_BACSU/590-666DSDSYFAGKTIVL......TGKLEELS----RNEA...KAQIEALGGKL.........................TGSV.S
DNLJ_MYCLE/607-683SVLPTCEGLTIVV......TGSLAGFS----RDDA...KEAIVARGGKV.........................AGSV.S
O44844_CAEEL/154-256KRPPLFYGFNFTILP...TTNRRMQAT----REFW...NRIIEGFGGTCSM....................SPIPGEA.G
O49549_ARATH/1115-1196QFHGFSKKLVLSC.......SGLTVEE----KTVI...AEFAELSGVTI.........................SKNW.D
O49549_ARATH/1230-1322KKPKLFTGLKFYI......MGDFELAY----KGYL...QDLIVAAGGTILRR...................RPVSSDD.N
DNLJ_BORBU/583-659GENKLLAGKKFCI......TGTFNGYS----RSII...IDKLKNKGAIF.........................NTCV.T
BRCA1_RAT/1588-1669PKERAERDISMVV..........SGLT----PKEVMIVQKFAEKYRLAL.........................TDVI.T
BRCA1_RAT/1701-1787SQEKLFEGLQIYC......CEPFTNMP----KDEL...ERMLQLCGASVVK....................ELPLLTR.D
PESC_SCHPO/348-428SNTSLFSNFTFFL.........SREVP----RFSL...EFVIRAFGGKVGWDPI..............LGSGSPFSES.D
RFC1_SCHPO/236-313GNSDCLSGISFVI......TGILETLT----RQEA...TDLIKQYGGKV.........................TGAP.S
DNLJ_AQUAE/619-696KVADVLKGKTFVF......TGTLDCCS----REKA...GEIVEMLGGKF.........................SNSV.T
CHS5_CANAL/164-246HKMTDLSGITVCLG....DLTPNDQFN----KEDI...EEALKNMGAKY............................P.V
DNLJ_TREPA/562-642QAESPLRGKSFCF......SGSLRNGD----RATI...H.RIRALGGVV.........................RTSV.T
DNLJ_TREPA/654-729ETVHPLQGKSFYF......SGASRSMN----HKHA...QEKVRALGGDV.........................ASSV.T
DNLJ_CHLTR/581-657DKEAPLQGKVFVL......TGTLQQMT----RTQA...EERIRCLGGKV.........................SSSV.S
DNLJ_GEOSE/589-665PADSAFAGKTVVL......TGKLASMS----RNEA...KEQIERLGGRV.........................TGSV.S
O96271_PLAF7/208-298FDYLPFHNQKFVI......TGVFKNFT----RDEL...QSKIKEHGGSV.........................MTAV.S
PESC_LEIMA/317-390KVRELFRGLTFFI.........SREVP----AKHF...ALVINACGGRV........................ATDYV.P
RAP1_YEAST/121-195VSGPPLSNMKFYLN.....RDADAHDS----LNDIDQLARLIRANGGEVL......................DSKPRE.S
REV1_YEAST/161-236QSSKIFKNCVIYI.......NGYTKPG----RLQL...HEMIVLHGGKFL.......................HYLSS.K
DNLJ_ECOLI/593-669EIDSPFAGKTVVL......TGSLSQMS----RDDA...KARLVELGAKV.........................AGSV.S
PARP1_CHICK/382-460PQDKPLTNMKILT.......LGKLSKN----KEEV...KNIVEELGGKM.........................TTTA.N
DNLJ_THET8/589-664KGGEALKGLTFVI......TGELSR.P----REEV...KALLRRLGAKV.........................TDSV.S
DNLJ_ZYMMO/645-721LASSPLSGKIIVF......TGSLQKIT----RDEA...KRQAENLGAKV.........................ASSV.S
RAD4_SCHPO/2-79GSSKPLKGFVICC.......TSIDLKQ----RTEI...STKATKLGAAY.........................RSDF.T
RAD4_SCHPO/97-172HFLPTLFKCRVCL.......TNIGQPE----RSRI...ENYVLKHGGTF.........................CPDL.T
RAD4_SCHPO/298-371NEAKLFKNLTFYL..........YEFP----NTKVSRLHKCLSDNGGQI.........................SEFL.S
RAD4_SCHPO/392-473SLVPYFNGLSIHL..........TGFK----GEELSHLKKALTILGAVV.........................HEFL.G
RFC1_DROME/232-309GSPDCLSGLTFVV......TGVLESME----REEA...ESVIKEYGGKV.........................MTVV.G
TDT_CHICK/27-111GYEIKFNKLVIFIM.....QRKMGMTR----RTFL...MELARSKGFRV.........................ESEL.S
BRCA1_HUMAN/1642-1723STERVNKRMSMVV..........SGLT----PEEFMLVYKFARKHHITL.........................TNLI.T
BRCA1_HUMAN/1756-1842QDRKIFRGLEICC......YGPFTNMP----TDQL...EWMVQLCGASVVK....................ELSSFTL.G
RFC1_YEAST/153-230GKPNCLLGLTIVF......TGVLPTLE----RGAS...EALAKRYGARV.........................TKSI.S
RT107_YEAST/2-103STSLLFEQLNFLI.......LVAAEAE----LPIAHSTRKLLMDNSCNNC......................QIYELY.N
RT107_YEAST/117-213NPFHLLRDCQVYI........SKSSFN----KCEYILYSDLLHLLGGTL.........................VNYI.S
RT107_YEAST/261-352PNKTLFKNHHFAI.......SPDLNFF----TPLYWFLKGFIEDLDGKV...............................
RT107_YEAST/370-453FHAKLFTSKELTVA.....YTNYFGSQ----RFYI...QRLVEILGGLS.........................TPEL.T
RT107_YEAST/827-910ARFNELPNYDLKA.......VCTGCFH----DGFNEVDIEILNQLGIKI...............................
YPT4_CAEEL/930-1012CVPEKFPVSSFHI..........YIED----RTDDNVTNEFTTKFQSIT.........................SDEA.M
YPT4_CAEEL/1049-1141ATTPFLYGVHVAL..........CMKN----CPYLASLTAIIQGQGGTM............................L.D
TDT_XENLA/27-111QHNVKFKEIVLFLV.....ERKMGSSR----RTFL...MELARKRGFQT.........................EIEL.S
DPB11_YEAST/111-207FSFKYLHNFNIFI.......GRITDTN----ITSIDSLVRSIKKLGCSSYNYQNFVIK.......DTSSHNDDDDQGQ.N
DPB11_YEAST/322-405NSTLIFKNCAFII......HHIFPGNH----RSIL...TKIVVQNGGKI...............................
DNLJ_RHOMR/633-709AAESPVRGKTFVL......TGALPHLT----RKEA...EELIKRAGGRV.........................ASSV.S
PESC_YEAST/355-436PVASLFSAFVFYV.........SREVP----IDIL...EFLILSCGGNVISEAAM.............DQIENKKDID.M
DNLJ_SYNY3/591-667TDSGKLKGKTFVL......TGTLPNLS----RLEA...QELIEQSGGKV.........................TSSV.S
P78622_EMEND/323-400GAENCLAGLTFVF......TGVLDTLG----REEG...QALVKRYGGKV.........................TTAP.S
RHP9_SCHPO/535-640SNQLIFDDCVFAFS....GPVHEDAYD----RSAL...ETVVQDHGGLVLDTGLRPLFNDPFKSKQKKLRHLKPQKRS.K
FCP1_YEAST/499-580LKQKVFQNCYFVFSG...LIPLGTDIQ----RSDI...VIWTSTFGATS.........................TPDI.D
DNLI4_YEAST/681-767PISNIFAGLLFYVLSDYVTEDTGIRIT----RAEL...EKTIVEHGGKLIY....................NVILKRH.S
DNLI4_YEAST/836-928FPLFLFSNRIAYV......PRRKISTE----DDII...EMKIKLFGGKI..............................T
Q09615_CAEEL/251-326NVSRIMEGFSVFV.......NGYTDPP----ALVI...RDLMISHGGEY.........................HCYY.Q
BRC1_SCHPO/14-91HYTIIFKVVAYYS.........ALQPN----QNELRKKELFIKNDGKAL........................SFPYD.W
BRC1_SCHPO/105-183NPYLLFKGICASS.......CQIDSYQ----SSLI...DDALETFGGRF.........................SKGL.M
BRC1_SCHPO/216-293LFRNVLHGKRIYF.......SNDLNLP----TNFRHSLQKFSVGIGAKI.........................AESI.N
BRC1_SCHPO/311-386PSVGFLKDQMVAV.......TNYTDAA----RIYL...EKLLLACGATY.........................TKDL.K
BRC1_SCHPO/767-859QGPSLLEDYVVYL........TSKTVA----PENVPAVISIVKSNGGVCSTLNVYNKRLA..RHLEDGNVVLITCNED.S
CHS5_YEAST/166-249HKMTDMSGITVCLG....PLDPLKEIS----DLQI...SQCLSHIGAR.............................P.L
Q18104_CAEEL/407-489QVPEIFPVSSFHI..........FIDK----ETDDNVTNKFLLVFQSIT.........................SMEP.L
Q22590_CAEEL/206-280HRLGVFEGLSLFF..........HGFK----QTEIDDMLRSLENTGGKL..........................APS.P
Q57489_DICNO/36-112IIDAPLLGKTVVI......TGTLPSLS----RAEA...QKRLETLGAKV.........................TSQV.S
XRCC1_MOUSE/315-390ELGKILQGVVVVL.......SGFQNPF----RSEL...RDKALELGAKY.........................RPDW.T
Q61944_MOUSE/341-418GAENCLEGLTFVI......TGVLESIE----RDEA...KSLIERYGGKV.........................TGNV.S
TDT_ONCMY/24-108QVEVKFKEVTLELV.....ERKMGSSR----RNFL...TRLARSKGFRV.........................EDVL.S
CFR1_SCHPO/167-243LRMIDLTGIQVCV..........GNMV----PNEMEALQKCIERIHAR................................
Q94046_CAEEL/514-600DPELYLTGIHFHCFD..SEKLFEDKLD----RKNL...EFMIKYHGGDIEFE...................ASKFHER.I
Q94046_CAEEL/620-694ENFRPYLGKLFSL.......SGFDSSE----RAAI...SFMAEMMGAKI.........................TPFL.A
Q94046_CAEEL/930-1016RNKPVFEDIEFHV.......TRFVEPN----QNDL...VRLIELGGGNV...............................
DNLJ1_STRCO/643-719EGPRPLEGLTVVV......TGTLENFT----RDGA...KEALQSRGAKV.........................TGSV.S
DNLJ_CHLPN/583-659KSGSTCFGKAFVI......TGTLEGMS----RLDA...ETAIRNCGGKV.........................GSSV.S
DNLJ_RICPR/610-686REQNILTGKIVVF......TGSLSTIS----RVEA...KEIAEKLGAKV.........................TASV.S
PARP1_ARATH/394-471SRSERLADLKVSI...........AGN----TKERQPWKKRIEEAGAEF.........................HANV.K
Q9ZR18_ARATH/553-629RKRRNLAHVRVLF.........SQNLD----DETVKQQKKIMVRLGISP..........................ASS.S
Q9ZWC2_ARATH/495-577EQTPAFTKELVLC......GSALSKSD----KKLM...ESLAVRFNATI.........................SRYW.N
Q9ZWC2_ARATH/611-717NKPKLFEGLKFYF......FGDFYKGY----KEDL...QNLVKVAGGTILNTED..............ELGAESSNNV.N

PF12738

ECT2_MOUSE/179-242S.....KVTHLV----A...NCT--------------------QGEK-------------FRVAVSLG.TPIMKPEW---
A1CWA7_NEOFI/345-407Q.....ENTHLV----T...AHG--------------------NSEK-------------CAAAKEWG.LHVVNHLW---
A2R3M9_ASPNC/121-184K.....NVTHLI----A...RNT--------------------EGEK-------------YKFATQWG.IRIVTVKW---
A5B5A0_VITVI/458-520R.....SITHLV----C...WKF--------------------EGRK-------------YSLAKKFK.TLIVNHRW---
A7F1C2_SCLS1/119-182K.....QITHLI----S...FRT--------------------EGNK-------------YKAAKSWG.LRIVSAEW---
A7S5M3_NEMVE/449-511R.....TNTHLV----C...RSS--------------------ESLK-------------YKKAREWG.IPCINAKW---
A9PDJ1_POPTR/4-66N.....STTHLV----C...WKF--------------------EGRK-------------YELASKFD.TLVVNHRW---
A9RB53_PHYPA/468-530S.....KITHLL----C...KVQ--------------------AGEK-------------YENAERLG.IRCVTANW---
B0DMV8_LACBS/502-564K.....KATHLL----C...PSG--------------------TGLK-------------FDKAQEWG.IPVVSIGW---
B2VU23_PYRTR/350-412Q.....ENTHLI----A...AHK--------------------NSEK-------------CEAAVEWG.VNIVNHLW---
B2W796_PYRTR/229-291I.....DTTHFV----C...TEG--------------------RGPS-------------WEKAVENN.IPVVVPDW---
B2W7P6_PYRTR/114-177K.....SVTHLI----A...ATP--------------------SGKK-------------YEHALNWG.MKIVALEW---
B3NSB0_DROER/190-254R.....STTHVV----F...KDG--------------------LLST-------------YKKAAEWK.IPVVSILW---
B3RL44_TRIAD/702-764R.....KNTHLI----C...KSP--------------------SGEK-------------FFKAKEWR.IFTVNCKW---
B4DWW2_HUMAN/9-75K.....QVTHVI----F...KDG--------------------YQST-------------WDKAQKRG.VKLVSVLW---
B4H593_DROPE/186-250R.....NTTHVI----F...KDG--------------------LLST-------------YKKAVEWK.IPVVSVLW---
B4KSD3_DROMO/76-140R.....NTTHVV----F...KDG--------------------LLST-------------YKRAQSWN.IPIVSILW---
B5FXA4_TAEGU/27-93K.....HVTHVV----F...KDG--------------------RLST-------------WKKAQKMG.VKIVSVLW---
B6HL54_PENCW/128-191K.....TVTHLI----A...RNS--------------------DGEK-------------YKFATQWN.IKVVSVKW---
B6Q6C3_PENMQ/111-174K.....TVTHLI----A...QQA--------------------SGAK-------------YKFATQWS.IKVVSAKW---
TOB1A_XENLA/202-265N.....ESTHLI----V...QEA--------------------KGQK-------------YECARKWN.VHCISVQW---
B8BJJ5_ORYSI/208-271R.....RCTHLV----S...NIS--------------------FGDK-------------YVVAQKWGNIHIVVPKW---
B8LKV4_PICSI/41-103N.....GNTHLV----C...WNF--------------------LGAK-------------YSLAKRLR.LTVVNHRW---
B9GSH3_POPTR/111-175N.....RVTHLI----C...YKF--------------------EGEK-------------YELANKMKKMKLVNHRW---
C0NFA4_AJECG/121-184K.....SVTHLI----A...RSG--------------------YGQK-------------YKYATLWK.ITVVSLKW---
C1FFW2_MICSR/561-624N.....KNTHLV----V...PYA--------------------EGKK-------------YEAAVGWG.LHAVTVEW---
C1GTX0_PARBA/624-691L.....RTTHLV----A...GRN--------------------RTAK-------------VREATRYPNVRIVTVQW---
C4M4C9_ENTHI/17-80R.....SVSFLL----S...KGL--------------------TSDK-------------ARHAKRWG.VPVLNHQW---
C5FMN4_ARTOC/111-174K.....TVTHLV----A...RVG--------------------EGKK-------------YKFAILWG.VKVVSLKW---
MU176_SCHPO/179-233TE..ENPVSHAV----LYDCSQE--------------------TLKK-------------ISSAQVP..IVCVSPKW---
RAD4_SCHPO/105-167R.....DVTHLI----A...GTS--------------------SGRK-------------YEYALKWK.INVVCVEW---
Q014F9_OSTTA/116-179S.....KTTHLV----C...YRA--------------------GSSA-------------YVQAVTRGRVAVVNHLW---
Q0UDZ8_PHANO/130-193K.....AVTHLI----A...ATP--------------------TGKK-------------YEHAVNWR.MKIVSLEW---
Q16W28_AEDAE/219-283K.....DTTHVI----F...KDG--------------------LLST-------------YQKAKKMN.VPVVSILW---
Q1K5Z2_NEUCR/339-401A.....DNTHLI----T...ARM--------------------NGEK-------------CEAAKEWN.IEIINHLW---
Q2H787_CHAGB/324-387K.....QVTHLI----V...YKP--------------------EGRK-------------YHAAKNWG.VTTVSVEW---
Q2R9I2_ORYSJ/195-257K.....KVTHLI----C...KFA--------------------SGPK-------------YEAYYSRG.IPTITAEW---
Q4CP92_TRYCC/1-63T.....STNVLI----A...GRS--------------------EGGK-------------CRVARERG.IPCVTPAW---
Q4PHX3_USTMA/599-667E.....SLTHVV----CATQESF--------------------EGKH-------------AQHARSCG.VPVVGLDF---
Q4T8H9_TETNG/716-778R.....SNTVLI----C...KEP--------------------VGLK-------------YEKAKEWK.IPCVNAQW---
Q55XE8_CRYNB/497-562D....RDVTHLI----S...FRN--------------------HGIK-------------VRRAKAWG.SQIVKHDW---
Q5TRD6_ANOGA/110-173T.....KVTHLI----C...NSS--------------------GGEK-------------YRYAMTFR.LAIIRPNW---
Q6CN34_KLULA/351-414K.....KNTHLI----S...PIA--------------------SGKK-------------FEAARAWACCTAANHLW---
PAXI1_MOUSE/102-165K.....KCTHLI----V...PEP--------------------KGEK-------------YERAVKRTSIKIVTPDW---
Q6Z553_ORYSJ/10-72R.....SITHLV----C...WRL--------------------EGKK-------------YDIARRLR.TRVVSHRW---
Q70X85_ARATH/188-251K.....SCTHLI----A...DAA--------------------EGDK-------------YKVARKWGHIQIVTRKW---
Q98SN2_XENLA/642-715KPDDPDRTTHLI----A...ARA--------------------GTEK-------------VRKAQNCKHLHVVNPEW---
Q9FVX6_ARATH/479-541R.....KVTHLI----C...NFA--------------------KGDK-------------YVRASKWG.IISVTPDW---
Q9U7D8_DROME/117-180T.....KTTHLI----C...NHS--------------------GGEK-------------YQYAKTFR.LTVVRPAW---

PF00533

Y4211_ARATH/1089-1168Y-----QATHFI....A---PEI...................RRTEK.............FFAAAASG-SWILKTDYVAD
MDB1_SCHPO/384-455D-----ETDFVI....L---GSP.................PLRRTHK.............FLLATSLG-IPLVSSQYLTD
MDB1_SCHPO/485-573E-----KDTIIL....A---QPDN...............DQEGRNMS.............ATGLNVYK-IELVALSILRD
DNLI3_MOUSE/939-1006G-----SATHVL.....---........................................GNREKNTD-AQLVSSEWIWA
ECT2_MOUSE/266-341E-----RCTHLI....V---EEN....................TVKD.............LPFEPSKK-LFVVKQEWFWG
PAXI1_HUMAN/701-776R-----SNTVLI....C---KEP....................TGLK.............YEKAKEWR-IPCVNAQWLGD
PAXI1_HUMAN/860-934Q-----KCTHLI....A---SKV...................TRTVK.............FLTAISVV-KHIVTPEWLEE
TDT_HUMAN/27-111D-----SVTHIV....A---ENNSG.............SDVLEWLQA.............QKVQVSSQ-PELLDVSWLIE
RAD9_YEAST/994-1109R-----ELALKL....A---WKPHSLFADCR..FACLITKRHLRSLK.............YLETLALG-WPTLHWKFISA
XRCC1_HUMAN/538-616D-----RVQFVI....T---AQE..................WDPSFE.............EALMDNPS-LAFVRPRWIYS
Q93161_CAEEL/981-1063S-----NTTHVI....V---KTDEN.............GALETDSLD.............LLLWVFNG-AIIVKEQWMVD
PARP4_HUMAN/1-81P-----QCTHII....L---DNA.................DVLSQYQ.............LNSIQKNH-VHIANPDFIWK
TOPB1_HUMAN/101-176V-----SVTHLI....A---GEV....................GSKK.............YLVAANLK-KPILLPSWIKT
TOPB1_HUMAN/195-271N-----ECTHLI....V---QEP....................KGQK.............YECAKRWN-VHCVTTQWFFD
TOPB1_HUMAN/354-431E-----DVTHVI....V---GDY..................DDELKQ.............FWNKSAHR-PHVVGAKWLLE
TOPB1_HUMAN/548-620R-----TVADYA....V---VPL.......................L.............GCEVEATV-GEVVTNTWLVT
TOPB1_HUMAN/641-725F-----ASTHLI....L---KER....................GGSK.............YEAAKKWN-LPAVTIAWLLE
TOPB1_HUMAN/900-978E-----TVTHFI...YQ---GRP..................NDTNRE.............YKSVKERG-VHIVSEHWLLD
TOPB1_HUMAN/1260-1338P-----TCTHIV....V---GHP...................LRNEK.............YLASVAAG-KWVLHRSYLEA
Q20129_CAEEL/451-529S-----ATNVVV....V---SPN.................QQERITI.............RKHLHQED-IAIVTVGWVVE
Q20129_CAEEL/587-659Y-----AEFVIF....G---HSG.....................................PMHELISF-DAVVTDFYIYA
Q20129_CAEEL/679-749P-----KDFIIM....I---DAE......................................DNPPRYH-SRTLDFSWIIA
DNLJ_HAEIN/592-668S-----KTDFVI....A---GDA...................AG.SK.............LAKAQELN-ITVLTEEEFLA
DNLI4_CANAL/673-756L-----ATNYQI....M---VIT..................ERELPV.............SSQYLSKG-IDLVKPIWIYE
PESC_DANRE/323-403E-----TITHHI....V---DRP.....................................SMDKQYIN-RYYIQPQWVYD
Q20129_CAEEL/128-204H-----ETTHLV....T---EKA...................EQTEK.............YKAAVNNS-IKLMRIGWIDD
O76369_CAEEL/929-1023S-----TTTHCV....V---KTNEN.............GILETESLE.............IFFWIFNG-TIIVKEQWMSD
PAXI1_MOUSE/8-80A-----LASHII....S---EDG...................DNPEV.............GEAREVFD-LPVVKPSWVTL
PAXI1_MOUSE/94-170K-----KCTHLI....V---PEP...................KGEKY.............ERAVKRTS-IKIVTPDWVLD
PAXI1_MOUSE/588-668S-----RCTHLL....C---ASQ....................VSSM.............YTQALRER-KRCVTAHWLNT
PARP1_MOUSE/385-463K-----ASLCIS....I---KKE.................VEKMNKK.............MEEVKEAN-IRVVSEDFLQD
DNLI4_HUMAN/654-730P-----DTYCVI....A---GSE....................NIRV.............KNIILSNK-HDVVKPAWLLE
DNLI4_HUMAN/814-898E-----GVSHVI....I---GEDH...............SRVADFKA.............FRRTFKRK-FKILKESWVTD
TDT_AMBME/27-111E-----YVTHVV....S---EKNSG.............AEVLEWLQA.............KKAGSIPN-VAILDISWFTD
O16568_CAEEL/1044-1144A-----DDEKTPKPYWT---LSSFYKKKKWEQRSCIILKHSDSKIEK.............KWQSMHAM-YTLVDFSFLAE
PESC_HUMAN/322-402S-----RITHQI....V---DRP.....................................GQQTSVIG-RCYVQPQWVFD
TDT_MONDO/27-111N-----SVTHIV....A---ENNSG.............SDVLAWLKT.............HKMEKTTQ-FELLDISWLIE
O16229_CAEEL/378-460L-----TTTHVV....V---KVNPA.............GVLETDDLS.............LLVWIFNG-AIIVKEKWMTD
DNLJ_HELPY/577-652A-----KTDFLI....A---GEN...................PG.SK.............LALAQKHG-VSVLNEEELLK
DNLJ_BACSU/590-666K-----NTDLVI....A---GEA...................AG.SK.............LTKAQELN-IEVWNEEQLMG
DNLJ_MYCLE/607-683K-----KIAYVV....V---GDL...................PG.YK.............YDKAVELG-VPILNEDGFRL
O44844_CAEEL/154-256K-----IPYHLV....K---RNLKVPSASID..SSVVLYFNDSVLHE.............KWTFANNC-ISFLGMGWLVE
O49549_ARATH/1115-1196S-----TVTHVI....A---SINEN..............GACKRTLK.............FMMAILEG-KWILTIDWIKA
O49549_ARATH/1230-1322E-----ASTIVVFSVEP---SKKKT..............LTQRRSDA.............EALAKSAR-ARAASSSWVLD
DNLJ_BORBU/583-659G-----SLDFLI....V---GEK...................AG.SK.............LKKALSLN-IKIMSFEDIKS
BRCA1_RAT/1588-1669E-----ETTHVI....I---KTDAE..............FVCERTLK.............YFLGIAGG-KWIVSYSWVIK
BRCA1_RAT/1701-1787T-----GAHPIV....L---VQPS...............AWTEDNDC.............PDIGQLCK-GRLVMWDWVLD
PESC_SCHPO/348-428P-----VITHHI....C---DRP.....................................HISQKYEG-RIYIQPQWVYD
RFC1_SCHPO/236-313V-----RTDFIL....L---GEN...................AGPRK.............VETIKQHK-IPAINEDGLFY
DNLJ_AQUAE/619-696S-----KTDYLV....V---GKD...................PGATK.............LSKAKKYG-VKTITEEEFVN
CHS5_CANAL/164-246Q-----QQVKVD....T---THFLC.............TRENKQNPE.............YVKANDMN-IPIIRPEWLKA
DNLJ_TREPA/562-642R-----DLSYLIFESLS---QPY...................RTAQK.............LKKEQGVA-LEIISEDEFCR
DNLJ_TREPA/654-729A-----QLDYLV.....---...........................FYS......QSTRYRTACALG-IQIISEETLHK
DNLJ_CHLTR/581-657K-----STYAVI....A---GSE...................AG.GK.............LKKAQDLG-LSIWNESELLR
DNLJ_GEOSE/589-665R-----STDLVI....A---GED...................AG.SK.............LEKAQQLG-IEIWDESRFLQ
O96271_PLAF7/208-298T-----KTNYLV....H---GEY...................LEDGRLFNEGRKYTKAFELQQQNKSN-IKILNEEELLK
PESC_LEIMA/317-390S-----NITHVV....V---DRPA................LP..................PGMKKHDQ-LEYVQPQYIFD
RAP1_YEAST/121-195K-----ENVFIV....S---PYN..........................................HTN-LPTVTPTYIKA
REV1_YEAST/161-236K-----TVTHIVASNLP---LKK.......................................RIEFAN-YKVVSPDWIVD
DNLJ_ECOLI/593-669K-----KTDLVI....A---GEA...................AG.SK.............LAKAQELG-IEVIDEAEMLR
PARP1_CHICK/382-460K-----ATLCIS....T---QKE.................VEKMSKK.............MEEVKDAK-VRVVSEEFLKD
DNLJ_THET8/589-664R-----KTSYLV....V---GEN...................PG.SK.............LEKARALG-VPTLTEEELYR
DNLJ_ZYMMO/645-721K-----KTNLVV....A---GEA...................AG.SK.............LSKAKELD-ISIIDEDRWHR
RAD4_SCHPO/2-79K-----DVTHLI....A---GDF..................DTPKYK.............FAAKSRPD-IKIMSSEWIPV
RAD4_SCHPO/97-172R-----DVTHLI....A---GTS....................SGRK.............YEYALKWK-INVVCVEWLWQ
RAD4_SCHPO/298-371S-----TIDFVVIPHYF---P.......................................VDELPIFS-FPTVNEWWIER
RAD4_SCHPO/392-473V-----QRSILL....V---NTNEP..............FSMKTRFK.............IQHATEWN-VRVVGVAWLWN
RFC1_DROME/232-309K-----KLKYLV....V---GEE...................AGPKK.............LAVAEELN-IPILSEDGLFD
TDT_CHICK/27-111D-----SVTHIV....A---ENNSY.............PEVLDWLKG.............QAVGDSSR-FEILDISWLTA
BRCA1_HUMAN/1642-1723E-----ETTHVV....M---KTDAE..............FVCERTLK.............YFLGIAGG-KWVVSYFWVTQ
BRCA1_HUMAN/1756-1842T-----GVHPIV....V---VQPD...............AWTEDNGF.............HAIGQMCE-APVVTREWVLD
RFC1_YEAST/153-230S-----KTSVVV....L---GDE...................AGPKK.............LEKIKQLK-IKAIDEEGFKQ
RT107_YEAST/2-103E-----NLKDVK....T---DKDWFMNKFGPQTVHFVISNTINFPFY.............KIVYFDLL-IPVVSHTWVQD
RT107_YEAST/117-213N-----RTTHVI....V---QSPQDPIIATV.SKLTFGSFSSSSTNK.............HTEKPLRE-WKFVYPIWILY
RT107_YEAST/261-352.-----.TPLSF....S---DDLKSVYQAFPDIDCYIGHSANSPILE.............KTKSIKPE-IHVGNVSWLFY
RT107_YEAST/370-453R-----KNTHLITKSTI---GKK..................FKVAKK.............WSLDPQNA-IIVTNHMWLEQ
RT107_YEAST/827-910.-----...........---..FDNIKETDKLNCIFAPKILRTEKFL.............KSLSFEPL-KFALKPEFIID
YPT4_CAEEL/930-1012I-----TTTHVV....V---KTTED.............GILETDDLN.............LLIWIFHG-SIIVRDTWMVD
YPT4_CAEEL/1049-1141K-----FPDKDA....F---NKGSHPYLHKNLGPIFLLHDGTGDLDL.............YRSDPDKM-FTLFTEQQFMD
TDT_XENLA/27-111D-----SVTHIV....A---ENNSG.............AEVLEWLQS.............KKLGFTVK-THILDISWFTE
DPB11_YEAST/111-207G-----QISIFV....T---DTL....................LGAR.............VNAAIEQN-IPIVHFKWILD
DPB11_YEAST/322-405.-----...........---ETSYLSGIYDHSYYIIPSNKALDSFND.............LPEIIDDN-DGIVTEFFIER
DNLJ_RHOMR/633-709R-----NTDYVV....V---GEN...................PG.SK.............YDRARQLG-IPMLDEDGLLR
PESC_YEAST/355-436S-----KVTHQI....V---DRP.....................................VLKNKVAG-RTYIQPQWIFD
DNLJ_SYNY3/591-667T-----KTDYVL....L---GDK...................PG.SK.............AAKAESLG-IKLLSEAEFLQ
P78622_EMEND/323-400G-----KTSFVV....L---GSD...................AGPSK.............LATISKHK-LKTISEEGLFE
RHP9_SCHPO/535-640S-----WNQAFV....V---SDT..................FSRKVK.............YLEALAFN-IPCVHPQFIKQ
FCP1_YEAST/499-580Y-----LTTHLI....T---KNP..................STYKAR.............LAKKFNPQ-IKIVHPDWIFE
DNLI4_YEAST/681-767I-----GDVRLI.....---....................SCKTTTE.............CKALIDRG-YDILHPNWVLD
DNLI4_YEAST/836-928D-----QQSLCN....L---IIIPYTDPILRKDCMNEVHEKIKEQIK.............ASDTIPKI-ARVVAPEWVDH
Q09615_CAEEL/251-326H-----GITSYT....I---ASS....................IATA.............KINRIREN-EIFIKADWITE
BRC1_SCHPO/14-91K-----LATHVI....C---DDF....................SSPN.............VQEGSKRS-LRLAKTNWIRD
BRC1_SCHPO/105-183K-----SMTHLF....T---YSG.................MGAKCKK.............VLDKPSLS-IKLIHPQWLLD
BRC1_SCHPO/216-293D-----CDIFIG.....---....................LKRDTIE.............FNLASNKN-TTIGTISWLLN
BRC1_SCHPO/311-386P-----TNTLLI....A---ASS....................YGQK.............YGAAKVWN-IPTVHHSWLYS
BRC1_SCHPO/767-859H-----IWTNFL.....---........................................DNASQNKT-IFLQNYDWLIK
CHS5_YEAST/166-249Q-----RHVAID....T---THFVCN...........DLDNEESNEE.............LIRAKHNN-IPIVRPEWVRA
Q18104_CAEEL/407-489P-----NTTHCI....V---QTEFD.............GTLKTNDLD.............LLIWILNG-IIFVKESWMTD
Q22590_CAEEL/206-280T-----LATHVVYNPDN---DEV.....................................ETLAVSSN-QVHVTKEWFWV
Q57489_DICNO/36-112R-----QTDFLL....L---GAD...................AG.SK.............LARAQAFS-VRLLMKRSSNV
XRCC1_MOUSE/315-390P-----DSTHLICAFA.---.......................NTPK.............YSQVLGLG-GRIVRKEWVLD
Q61944_MOUSE/341-418K-----KTNYLV....M---GRD...................SGQSK.............SDKAAALG-TKILDEDGLLD
TDT_ONCMY/24-108D-----DVTHVV....A---EDNQA.............EVLWAWLMG.............HGLRDVSR-LALLDISWFTD
CFR1_SCHPO/167-243.-----...........---...PIQTSVRI..DTTHFICSSTGGPE.............YEKAKAAN-IPILGLDYLLK
Q94046_CAEEL/514-600H-----QITHVL....V---DSC....................RNTN.............VMTSLEHR-KRIVSIQWIID
Q94046_CAEEL/620-694R-----QNDLLI....A---KQP.....................ADK.............VTRAQEWK-VPVVNFQWIAD
Q94046_CAEEL/930-1016.-----...HSE....K---PDPKYLAKCVETEQPFIIISCENDARF.............LSYLAGSK-LPIYNVDLVLF
DNLJ1_STRCO/643-719K-----KTSFVV....V---GDN...................PG.SK.............YDKAMQLK-VPVLNEDGFAV
DNLJ_CHLPN/583-659K-----QTDYVV....M---GNN...................PG.SK.............LEKARKLG-VSILDQEAFTN
DNLJ_RICPR/610-686L-----NTDLVI....A---GVN...................GG.SK.............LKKAKELN-IKIIDEVEWLA
PARP1_ARATH/394-471K-----GTSCLV....V---CGL.................TDIRDAE.............MRKARRMK-VAIVREDYLVD
Q9ZR18_ARATH/553-629A-----DSTHFI....A---DRF...................ARTRN.............MLEAIALG-KFVVTPIWLES
Q9ZWC2_ARATH/495-577P-----SVTHVI....A---STDEK..............GACTRTLK.............VLMGILNG-KWIINAAWMKA
Q9ZWC2_ARATH/611-717D-----QRSSSIVVYNI---DPPHGCALG.....EEVTIIWQRANDA.............EALASQTG-SRLVGHTWVLE

PF12738

ECT2_MOUSE/179-242--
A1CWA7_NEOFI/345-407--
A2R3M9_ASPNC/121-184--
A5B5A0_VITVI/458-520--
A7F1C2_SCLS1/119-182--
A7S5M3_NEMVE/449-511--
A9PDJ1_POPTR/4-66--
A9RB53_PHYPA/468-530--
B0DMV8_LACBS/502-564--
B2VU23_PYRTR/350-412--
B2W796_PYRTR/229-291--
B2W7P6_PYRTR/114-177--
B3NSB0_DROER/190-254--
B3RL44_TRIAD/702-764--
B4DWW2_HUMAN/9-75--
B4H593_DROPE/186-250--
B4KSD3_DROMO/76-140--
B5FXA4_TAEGU/27-93--
B6HL54_PENCW/128-191--
B6Q6C3_PENMQ/111-174--
TOB1A_XENLA/202-265--
B8BJJ5_ORYSI/208-271--
B8LKV4_PICSI/41-103--
B9GSH3_POPTR/111-175--
C0NFA4_AJECG/121-184--
C1FFW2_MICSR/561-624--
C1GTX0_PARBA/624-691--
C4M4C9_ENTHI/17-80--
C5FMN4_ARTOC/111-174--
MU176_SCHPO/179-233--
RAD4_SCHPO/105-167--
Q014F9_OSTTA/116-179--
Q0UDZ8_PHANO/130-193--
Q16W28_AEDAE/219-283--
Q1K5Z2_NEUCR/339-401--
Q2H787_CHAGB/324-387--
Q2R9I2_ORYSJ/195-257--
Q4CP92_TRYCC/1-63--
Q4PHX3_USTMA/599-667--
Q4T8H9_TETNG/716-778--
Q55XE8_CRYNB/497-562--
Q5TRD6_ANOGA/110-173--
Q6CN34_KLULA/351-414--
PAXI1_MOUSE/102-165--
Q6Z553_ORYSJ/10-72--
Q70X85_ARATH/188-251--
Q98SN2_XENLA/642-715--
Q9FVX6_ARATH/479-541--
Q9U7D8_DROME/117-180--

PF00533

Y4211_ARATH/1089-1168SK
MDB1_SCHPO/384-455CI
MDB1_SCHPO/485-573RI
DNLI3_MOUSE/939-1006CI
ECT2_MOUSE/266-341SI
PAXI1_HUMAN/701-776IL
PAXI1_HUMAN/860-934CF
TDT_HUMAN/27-111CI
RAD9_YEAST/994-1109CI
XRCC1_HUMAN/538-616CN
Q93161_CAEEL/981-1063CL
PARP4_HUMAN/1-81SI
TOPB1_HUMAN/101-176LW
TOPB1_HUMAN/195-271SI
TOPB1_HUMAN/354-431CF
TOPB1_HUMAN/548-620CI
TOPB1_HUMAN/641-725TA
TOPB1_HUMAN/900-978CA
TOPB1_HUMAN/1260-1338CR
Q20129_CAEEL/451-529CV
Q20129_CAEEL/587-659SI
Q20129_CAEEL/679-749SV
DNLJ_HAEIN/592-668QI
DNLI4_CANAL/673-756CI
PESC_DANRE/323-403SV
Q20129_CAEEL/128-204LW
O76369_CAEEL/929-1023CL
PAXI1_MOUSE/8-80SV
PAXI1_MOUSE/94-170CV
PAXI1_MOUSE/588-668VL
PARP1_MOUSE/385-463VS
DNLI4_HUMAN/654-730CF
DNLI4_HUMAN/814-898SI
TDT_AMBME/27-111CM
O16568_CAEEL/1044-1144CI
PESC_HUMAN/322-402SV
TDT_MONDO/27-111CM
O16229_CAEEL/378-460CL
DNLJ_HELPY/577-652RL
DNLJ_BACSU/590-666EL
DNLJ_MYCLE/607-683LL
O44844_CAEEL/154-256CI
O49549_ARATH/1115-1196CM
O49549_ARATH/1230-1322SI
DNLJ_BORBU/583-659YL
BRCA1_RAT/1588-1669SI
BRCA1_RAT/1701-1787SI
PESC_SCHPO/348-428SI
RFC1_SCHPO/236-313LI
DNLJ_AQUAE/619-696MI
CHS5_CANAL/164-246CE
DNLJ_TREPA/562-642LL
DNLJ_TREPA/654-729LI
DNLJ_CHLTR/581-657IL
DNLJ_GEOSE/589-665EI
O96271_PLAF7/208-298LL
PESC_LEIMA/317-390CL
RAP1_YEAST/121-195CC
REV1_YEAST/161-236SV
DNLJ_ECOLI/593-669LL
PARP1_CHICK/382-460VK
DNLJ_THET8/589-664LL
DNLJ_ZYMMO/645-721IV
RAD4_SCHPO/2-79LY
RAD4_SCHPO/97-172SI
RAD4_SCHPO/298-371CL
RAD4_SCHPO/392-473II
RFC1_DROME/232-309LI
TDT_CHICK/27-111CM
BRCA1_HUMAN/1642-1723SI
BRCA1_HUMAN/1756-1842SV
RFC1_YEAST/153-230LI
RT107_YEAST/2-103SV
RT107_YEAST/117-213HF
RT107_YEAST/261-352MF
RT107_YEAST/370-453CY
RT107_YEAST/827-910LL
YPT4_CAEEL/930-1012CL
YPT4_CAEEL/1049-1141LL
TDT_XENLA/27-111CM
DPB11_YEAST/111-207CQ
DPB11_YEAST/322-405CL
DNLJ_RHOMR/633-709LL
PESC_YEAST/355-436CI
DNLJ_SYNY3/591-667LL
P78622_EMEND/323-400LI
RHP9_SCHPO/535-640CL
FCP1_YEAST/499-580CL
DNLI4_YEAST/681-767CI
DNLI4_YEAST/836-928SI
Q09615_CAEEL/251-326SI
BRC1_SCHPO/14-91CV
BRC1_SCHPO/105-183CL
BRC1_SCHPO/216-293LF
BRC1_SCHPO/311-386SF
BRC1_SCHPO/767-859TV
CHS5_YEAST/166-249CE
Q18104_CAEEL/407-489CL
Q22590_CAEEL/206-280SL
Q57489_DICNO/36-112VA
XRCC1_MOUSE/315-390CH
Q61944_MOUSE/341-418LI
TDT_ONCMY/24-108SM
CFR1_SCHPO/167-243CE
Q94046_CAEEL/514-600VM
Q94046_CAEEL/620-694AY
Q94046_CAEEL/930-1016AM
DNLJ1_STRCO/643-719LL
DNLJ_CHLPN/583-659LI
DNLJ_RICPR/610-686FI
PARP1_ARATH/394-471CF
Q9ZR18_ARATH/553-629CA
Q9ZWC2_ARATH/495-577SL
Q9ZWC2_ARATH/611-717SI

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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