Sequence alignment for CL0459

PF12738

MCPH1_HUMAN/9-75-------------------VVAYV-------------------EVWSSNGTENY-------SK-TF---TTQLVDMGA--
ECT2_MOUSE/179-242-------------------LVLCF-------------------TGFRKKE...E-------LV-KL---VTLVHHMGG--
A2R3M9_ASPNC/121-184-------------------LSICI-------------------TGFEDMS...L-------RN-RI---QDTVTAHGA--
A7F1C2_SCLS1/119-182-------------------LRISL-------------------TGCDDTA...E-------RQ-DI---AEKIKANGG--
A7S5M3_NEMVE/449-511-------------------MSISV-------------------TGFTGQE....-------RQ-LV---RNMVFMIGA--
A9RB53_PHYPA/468-530-------------------VKFCV-------------------SQYSERD....-------RK-LL---RKLCYVLKV--
B0DMV8_LACBS/502-564-------------------VRMSL-------------------SGLDEAD....-------AH-GI---KRLMRAIGL--
B2VU23_PYRTR/350-412-------------------YKISI-------------------SSYTGEA....-------RV-YL---ENLIKASGA--
B2W796_PYRTR/229-291-------------------ITITP-------------------GHMPASL....-------RE-SL---QRSVERIGA--
B2W7P6_PYRTR/114-177-------------------LKICL-------------------TGFDNPD...Q-------RK-SI---QDKVDANGG--
B3RL44_TRIAD/702-764-------------------MVIAV-------------------TGYTGKE....-------RD-KV---KMIINAIGA--
B4H593_DROPE/186-250-------------------VVVYV-------------------DVRSGNDN..R-------SD-GV---KSIIADMGA--
B4KSD3_DROMO/76-140-------------------VIVYV-------------------EVRTGNDN..R-------SE-GV---KNIITKLGA--
B6HL54_PENCW/128-191-------------------LKICI-------------------TGFSDLP...F-------RA-YM---QKTTEENGA--
B6Q6C3_PENMQ/111-174-------------------LSICV-------------------TGFEDPS...Y-------RT-YL---QETTIANGA--
C0NFA4_AJECG/121-184-------------------LSICL-------------------TGFDDMN...H-------RN-SL---QKLITENGA--
C1FFW2_MICSR/561-624-------------------LRIST-------------------SLYDEDV....-------KS-SV---NMLCHLLGA--
C4M4C9_ENTHI/17-80-------------------YVICV-------------------SGYSTDE....-------RV-LL---GGMIEQFGG--
C5FMN4_ARTOC/111-174-------------------LSICI-------------------TGFENTD...F-------RS-HL---EKTVSENGG--
RAD4_SCHPO/105-167-------------------CRVCL-------------------TNIGQPE....-------RS-RI---ENYVLKHGG--
Q16W28_AEDAE/219-283-------------------VCIYV-------------------EVRSGTDN..R-------SD-GI---RDHLVSLGA--
Q1K5Z2_NEUCR/339-401-------------------MKITL-------------------SNYGGDA....-------RV-YL---ENLITAAGA--
Q2H787_CHAGB/324-387-------------------LLCCM-------------------TGFEDPD...E-------RE-QI---IGQIEANGG--
Q4CP92_TRYCC/1-63-------------------MLVTT-------------------TAIYGEE....-------LD-RI---KKDLHQQGV--
A0A0D1CFS9_USTMA/599-667-------------------LRLML-------------------LGFDPDSP..E-------LY-HA---QKLVVEMGG--
Q5TRD6_ANOGA/110-173-------------------VITCF-------------------TGIRKKD...E-------LT-HL---VHLIHSMGG--
Q6CN34_KLULA/351-414-------------------LKATY-------------------TNYYGEQ....-------RY-YI---QLLVEALGG--
PAXI1_MOUSE/102-165-------------------LTACL-------------------SQVSSED....-------RS-AL---WALVTFHGG--
Q6Z553_ORYSJ/10-72-------------------VVATV-------------------SGYHGDE....-------RH-RL---VRLIAETGA--
Q9U7D8_DROME/117-180-------------------VVTCF-------------------TGIRKKD...E-------LT-KL---VNLIHSMGG--
B9GSH3_POPTR/111-175-------------------ITMCL-------------------TGYQRQD....-------RD-DI---MTMVGLMGA--
D7SMI0_VITVI/4-66-------------------IIATV-------------------SGYHGVE....-------RS-NL---IKLISQTGA--
F4I701_ARATH/188-251-------------------LTICV-------------------TRIPADE....-------RK-GM---EKVISEYGG--
F4I701_ARATH/667-729-------------------LCICS-------------------SQHNEKN....-------VE-LL---RNLSVVLGA--
F6XFW7_XENTR/204-267-------------------CTICV-------------------TGLNSLD....-------RK-EV---QRLTTLHGG--
H0ZRM8_TAEGU/5-67-------------------....V-------------------EVWSSSRTENY-------SK-TF---EQQLLDMGA--
H3C8W0_TETNG/80-141-------------------.IMSV-------------------TGFVDAD....-------RD-DL---KLMAYLTGA--
I1QYC0_ORYGL/209-271-------------------.NICI-------------------TKLNVDE....-------RR-EL---AKIIVQNGG--
I1QYC0_ORYGL/675-736-------------------.RFCV-------------------SQYEEKD....-------RL-LL---KNLCFILGS--
Q4WQC2_ASPFU/345-407-------------------LKISL-------------------SNYVGEA....-------RI-YL---ENLITAAGA--
Q7JUM5_DROME/187-251-------------------IVVYV-------------------EVRTGNDN..R-------SE-GV---KSIIAKMGA--
U5GIH0_POPTR/4-66-------------------VVATV-------------------SGYHGSE....-------RF-NL---IKLISQSGA--

PF00533

Y4211_ARATH/1089-1168VFQDQE-----------HEPKFFI------------.......VSGPRSQ-----------RN-EY...QQIIRRLKG--
MDB1_SCHPO/384-455NKHTNL-----------VTSSFNL------------..............-----------TK-PM...KSFIRRNGL--
MDB1_SCHPO/485-573HRRTCF-----------NGKRLYI------------T.....KAIRDSMV-----------GD-SIHGLYSILETSGA--
ECT2_MOUSE/266-341FKVPPF-----------QDCILSF------------.......LGFSDEE-----------KH-SM...EEMTEMQGG--
PAXI1_HUMAN/701-776PGGKPC-----------SQHIISV------------.......TGFVDSD-----------RD-DL...KLMAYLAGA--
PAXI1_HUMAN/860-934KLTPEL-----------TPFVLFT------------........GFEPVQ-----------VQ-QY...IKKLYILGG--
TDT_HUMAN/27-111PQDIKF-----------QDLVVFI------------L.....EKKMGTTR-----------RA-FL...MELARRKGF--
RAD9_YEAST/994-1109RTGNVF-----------DKCIFVL------------........TSLFEN-----------RE-EL...RQTIESQGG--
XRCC1_HUMAN/538-616ELPDFF-----------QGKHFFL------------......YGEFPGDE-----------RR-KL...IRYVTAFNG--
Q93161_CAEEL/981-1063NVPQKF-----------PTTSFHI------------..........WIDE-----------RT-DINITNQFMEKFQA--
PARP4_HUMAN/1-81MVMGIF-----------ANCIFCL------------K.....VKYLPQQQ-----------KK-KL...QTDIKENGG--
TOPB1_HUMAN/101-176VYNMVM-----------SDVTISC------------.......TSLEKEK-----------RE-EV...HKYVQMMGG--
TOPB1_HUMAN/195-271FKCPIF-----------LGCIICV------------.......TGLCGLD-----------RK-EV...QQLTVKHGG--
TOPB1_HUMAN/354-431APEDLL-----------DGCRIYL------------.......CGFSGRK-----------LD-KL...RRLINSGGG--
TOPB1_HUMAN/548-620TEEGLF-----------SQKSFLV------------.......LGFSNEN-----------ES-NI...ANIIKENAG--
TOPB1_HUMAN/641-725TGMTPL-----------EDCVISF------------.......SQCAGAE-----------KE-SL...TFLANLLGA--
TOPB1_HUMAN/900-978EAPKPL-----------HKVVVCV------------.......SKKLSKK-----------QS-EL...NGIAASLGA--
TOPB1_HUMAN/1260-1338THEELK-----------KQYIFQL------------.......SSLNPQE-----------RI-DY...CHLIEKLGG--
Q20129_CAEEL/451-529GLGDLF-----------ENCMFYI------------.......CGVDESR-----------ME-KW...RRFLNETGA--
Q20129_CAEEL/587-659TQVGIF-----------SYHTYCV------------......HCSVDQEV-----------SD-DL...KEKIPLNGG--
Q20129_CAEEL/679-749PPILIF-----------NQRGFQL------------.......KCKDPFL-----------RD-RV...RDIIEDNGG--
DNLJ_HAEIN/592-668ASENLF-----------KDKTVVL------------......TGTLTQMG-----------RN-EA...KALLQQLGA--
DNLI4_CANAL/673-756VESDLF-----------SGIEFLI------------M....SDKREADGE-----------VT-TIEEMKAMVKQYGG--
Q20129_CAEEL/128-204VYSSVF-----------QDVKISF------------.......TGLNLTK-----------KQ-EL...YEKIGWMCG--
O76369_CAEEL/929-1023GKNALL-----------DAIREVN------------........KTNVMK-----------AL-KMGSYINAYNKHGN--
PAXI1_MOUSE/588-668PEESFL-----------LGCVFAI------------A.....DYPEQMSD-----------KQ-LLATWKRIIQAHGG--
PARP1_MOUSE/385-463PADKPL-----------SNMKILT------------.......LGKLSQN-----------KD-EA...KAVIEKLGG--
DNLI4_HUMAN/654-730KISNIF-----------EDVEFCV------------......MSGTDSQP-----------KP-DL...ENRIAEFGG--
DNLI4_HUMAN/814-898RRHTVY-----------LDSYAVI------------N....DLSTKNEGT-----------RL-AIKALE..LRFHGA--
O16568_CAEEL/1044-1144MRPKLL-----------EQCGFHI------------.........LETEL-----------LK-NREGWEEVIKLFGG--
TDT_MONDO/27-111IYEIKF-----------HEFVLFI------------L.....EKKMGATR-----------RT-FL...TDLARKKGF--
O16229_CAEEL/378-460NVPQQF-----------PVSSFHI------------..........WMDE-----------KT-DDKLTNAFMEKFPS--
DNLJ_HELPY/577-652KSSSVF-----------NNKTIVL------------......TGTLSK.P-----------RQ-EY...AQMLENLGA--
DNLJ_BACSU/590-666DSDSYF-----------AGKTIVL------------......TGKLEELS-----------RN-EA...KAQIEALGG--
DNLJ_MYCLE/607-683SVLPTC-----------EGLTIVV------------......TGSLAGFS-----------RD-DA...KEAIVARGG--
O44844_CAEEL/154-256KRPPLF-----------YGFNFTI------------LP...TTNRRMQAT-----------RE-FW...NRIIEGFGG--
DNLJ_BORBU/583-659GENKLL-----------AGKKFCI------------......TGTFNGYS-----------RS-II...IDKLKNKGA--
BRCA1_RAT/1588-1669PKERAE-----------RDISMVV------------..........SGLT-----------PK-EVMIVQKFAEKYRL--
BRCA1_RAT/1701-1787SQEKLF-----------EGLQIYC------------......CEPFTNMP-----------KD-EL...ERMLQLCGA--
RFC1_SCHPO/236-313GNSDCL-----------SGISFVI------------......TGILETLT-----------RQ-EA...TDLIKQYGG--
DNLJ_AQUAE/619-696KVADVL-----------KGKTFVF------------......TGTLDCCS-----------RE-KA...GEIVEMLGG--
CHS5_CANAL/164-246HKMTDL-----------SGITVCL------------G....DLTPNDQFN-----------KE-DI...EEALKNMGA--
DNLJ_TREPA/562-642QAESPL-----------RGKSFCF------------......SGSLRNGD-----------RA-TI...H.RIRALGG--
DNLJ_CHLTR/581-657DKEAPL-----------QGKVFVL------------......TGTLQQMT-----------RT-QA...EERIRCLGG--
O96271_PLAF7/208-298FDYLPF-----------HNQKFVI------------......TGVFKNFT-----------RD-EL...QSKIKEHGG--
PESC_LEIMA/317-390KVRELF-----------RGLTFFI------------.........SREVP-----------AK-HF...ALVINACGG--
DNLJ_ECOLI/593-669EIDSPF-----------AGKTVVL------------......TGSLSQMS-----------RD-DA...KARLVELGA--
PARP1_CHICK/382-460PQDKPL-----------TNMKILT------------.......LGKLSKN-----------KE-EV...KNIVEELGG--
DNLJ_THET8/589-664KGGEAL-----------KGLTFVI------------......TGELSR.P-----------RE-EV...KALLRRLGA--
DNLJ_ZYMMO/645-721LASSPL-----------SGKIIVF------------......TGSLQKIT-----------RD-EA...KRQAENLGA--
RAD4_SCHPO/2-79GSSKPL-----------KGFVICC------------.......TSIDLKQ-----------RT-EI...STKATKLGA--
RAD4_SCHPO/392-473SLVPYF-----------NGLSIHL------------..........TGFK-----------GE-ELSHLKKALTILGA--
RFC1_DROME/232-309GSPDCL-----------SGLTFVV------------......TGVLESME-----------RE-EA...ESVIKEYGG--
TDT_CHICK/27-111GYEIKF-----------NKLVIFI------------M.....QRKMGMTR-----------RT-FL...MELARSKGF--
BRCA1_HUMAN/1642-1723STERVN-----------KRMSMVV------------..........SGLT-----------PE-EFMLVYKFARKHHI--
BRCA1_HUMAN/1756-1842QDRKIF-----------RGLEICC------------......YGPFTNMP-----------TD-QL...EWMVQLCGA--
RFC1_YEAST/153-230GKPNCL-----------LGLTIVF------------......TGVLPTLE-----------RG-AS...EALAKRYGA--
RT107_YEAST/2-103STSLLF-----------EQLNFLI------------.......LVAAEAE-----------LP-IAHSTRKLLMDNSC--
RT107_YEAST/117-213NPFHLL-----------RDCQVYI------------........SKSSFN-----------KC-EYILYSDLLHLLGG--
RT107_YEAST/261-352PNKTLF-----------KNHHFAI------------.......SPDLNFF-----------TP-LYWFLKGFIEDLDG--
RT107_YEAST/370-453FHAKLF-----------TSKELTV------------A.....YTNYFGSQ-----------RF-YI...QRLVEILGG--
YPT4_CAEEL/930-1012CVPEKF-----------PVSSFHI------------..........YIED-----------RT-DDNVTNEFTTKFQS--
YPT4_CAEEL/1049-1141ATTPFL-----------YGVHVAL------------..........CMKN-----------CP-YLASLTAIIQGQGG--
DPB11_YEAST/111-207FSFKYL-----------HNFNIFI------------.......GRITDTN-----------IT-SIDSLVRSIKKLGC--
DNLJ_SYNY3/591-667TDSGKL-----------KGKTFVL------------......TGTLPNLS-----------RL-EA...QELIEQSGG--
RHP9_SCHPO/535-640SNQLIF-----------DDCVFAF------------S....GPVHEDAYD-----------RS-AL...ETVVQDHGG--
FCP1_YEAST/499-580LKQKVF-----------QNCYFVF------------SG...LIPLGTDIQ-----------RS-DI...VIWTSTFGA--
DNLI4_YEAST/681-767PISNIF-----------AGLLFYV------------LSDYVTEDTGIRIT-----------RA-EL...EKTIVEHGG--
DNLI4_YEAST/836-928FPLFLF-----------SNRIAYV------------......PRRKISTE-----------DD-II...EMKIKLFGG--
Q09615_CAEEL/251-326NVSRIM-----------EGFSVFV------------.......NGYTDPP-----------AL-VI...RDLMISHGG--
BRC1_SCHPO/14-91HYTIIF-----------KVVAYYS------------.........ALQPN-----------QN-ELRKKELFIKNDGK--
BRC1_SCHPO/105-183NPYLLF-----------KGICASS------------.......CQIDSYQ-----------SS-LI...DDALETFGG--
BRC1_SCHPO/216-293LFRNVL-----------HGKRIYF------------.......SNDLNLP-----------TN-FRHSLQKFSVGIGA--
BRC1_SCHPO/311-386PSVGFL-----------KDQMVAV------------.......TNYTDAA-----------RI-YL...EKLLLACGA--
CHS5_YEAST/166-249HKMTDM-----------SGITVCL------------G....PLDPLKEIS-----------DL-QI...SQCLSHIGA--
XRCC1_MOUSE/315-390ELGKIL-----------QGVVVVL------------.......SGFQNPF-----------RS-EL...RDKALELGA--
Q94046_CAEEL/514-600DPELYL-----------TGIHFHC------------FD..SEKLFEDKLD-----------RK-NL...EFMIKYHGG--
Q94046_CAEEL/620-694ENFRPY-----------LGKLFSL------------.......SGFDSSE-----------RA-AI...SFMAEMMGA--
DNLJ1_STRCO/643-719EGPRPL-----------EGLTVVV------------......TGTLENFT-----------RD-GA...KEALQSRGA--
DNLJ_RICPR/610-686REQNIL-----------TGKIVVF------------......TGSLSTIS-----------RV-EA...KEIAEKLGA--
PARP1_ARATH/394-471SRSERL-----------ADLKVSI------------...........AGN-----------TK-ERQPWKKRIEEAGA--
D0MI04_RHOM4/636-709...SPV-----------RGKTFVL------------......TGALPHLT-----------RK-EA...EELIKRAGG--
H9KXM3_CALJA/403-478..ENCL-----------EGLTFVI------------......TGVLESIE-----------RD-EA...KSLIERYGG--
Q5AZH7_EMENI/325-400..ENCL-----------AGLTFVF------------......TGVLDTLG-----------RE-EG...QALVKRYGG--

PF16589

K3WDG2_PYTUL/626-709-ERQIF...........KSMKFFV..................GSNVE.PS-----------RE-VL---QSLLQSAGG..
A2GB92_TRIVA/56-149-ETNLF...........KDCVFFI................LGYVGRGESS-----------RY-AM---TKLIEKNGGRT
E4V0Q5_ARTGP/707-798-KAHIF...........DGLSFFV.......MSES.LKP...T.KK...S-----------KA-DL---EQLIKANGG..
H6BN77_EXODN/749-843-RGKVF...........EGLTFYI.......MTES.TAP...APKK...S-----------KL-EL---EALVKANGG..
D7MMS2_ARALL/654-741-KTSVF...........SNMIFYF.................VNVPLS.HS-----------LE-TF---HKTVVENGG..
D7SQI2_VITVI/653-740-ETLIF...........SNMMFYF.................VNTPPT.HS-----------LD-SL---HKLVVENGG..
M0S2G9_MUSAM/640-728-ETFIF...........ANMVFYF.................VNIPPS.YS-----------VD-YF---HKVVVENGG..
K7LC24_SOYBN/506-593-GSLIF...........SNMMFYF.................VNVPQS.HS-----------PE-SL---HKLIAENGG..
Q5KPS9_CRYNJ/138-224-LPQIF...........AGLSFYI...................NGNTQPS-----------ME-QL---RKLLLQRGGTV
A8WS89_CAEBR/455-544-LRELF...........ENCIFYI..................IGKDQ.AT-----------KE-SL---VRLFNDTGA..
H2ANJ1_KAZAF/685-782-TSKIF...........DGLFFYI.......LSDY.FDTNENV.RI...S-----------KD-DL---QKLLLENGG..
I1BS31_RHIO9/47-133-KTTVF...........EALKIFI..................VSGIKDYS-----------KQ-AL---EKLAIENGA..
I2H6P9_TETBL/707-804-ISDLF...........HGLYFYI.......ISDY.IPDSDAQ.RI...D-----------RE-DI---CSLIIKNGG..
D2V2T9_NAEGR/209-297-AKTLF...........QSLTFYI..................VNYPP.EF-----------IS-IL---QREICSNGG..
D8M2G5_BLAHO/342-422-RKGIF...........SNLSFFIYEFKR....................D-----------YD-KV---KQCIESNDG..
G8BNV8_TETPH/119-211-SKHFF...........KDFQFYI................STTAFAK.ND-----------IS-YI---TELINYMGG..
M2N998_BAUCO/197-300-SSRIF...........ENLTFYI................NGSTAPAI.S-----------DH-KL---KHMISSHGG..
M2ZQ43_PSEFD/117-220-PPQIF...........NNLCFYI................NGCTAPV..S-----------DH-KL---KHIISTHGG..
V4Z6W2_TOXGO/178-272-NPCLF...........KNCVFYV.................DGDTLG.MD-----------DI-CF---KKLLLLFGG..
A3LW54_PICST/41-121-KSTLFTNREG......RSIRFYM....................EYSEPR-----------RL-HY---KALIETHGG..
G3AM46_SPAPN/45-124-QRNLF....ID..RDGRSLLFYI.................PRNEP...H-----------RS-HY---RQLIISYGG..
M3K224_CANMX/72-151-PKTIF....VD..KDNKTMLFYI.................PKEEP...N-----------RI-KY---RELIIKHGG..
Q59XT2_CANAL/89-168-PKPIF....VD..KDGKSMLFYI.................PEDEP...N-----------RN-KY---RDLIIRYGG..
A5DYD1_LODEL/66-146-RNQIFVT.RDG.....KPIAFYL...................GFNE.PN-----------RA-KY---VTAIIENGG..
G8BJX2_CANPC/111-190-HAHIFVT.SDN.....KPMPFFI...................PFDE.PN-----------RN-KY---KRMIMQNGG..
C4R0P7_PICPG/22-117-TEAIFVT.PIG.....TPYKFFL...............VGKDDSGK.EV-----------EA-VY---KERITQHGG..
C4VBY8_NOSCE/44-123-KKKIF...........TGISFYA.........................S-----------NT-TF---KKKIEDYGG..
R4XAV8_TAPDE/3-87-GSNLFTDPDG......EPLRFFL....................PMSLAS-----------RS-TF---KDKIEHNGG..
A7EAG9_SCLS1/12-89-GEALF...........EGMKFFI....................LQRVPM-----------RS-RW---IELIQSNGG..
G2YA12_BOTF4/12-89-GGVLF...........EGMKFFI....................LQRVPS-----------RS-RW---VELIRSNGG..
E3QRM6_COLGM/14-92-RGLLF...........KETSFYV....................FQRVPD-----------RK-TI---LDLITQNGG..
H1V395_COLHI/14-91-QGTLF...........RETSFFV....................TQRVPD-----------RK-NI---LDLITQNGG..
L2G6F7_COLGN/14-91-QGTLF...........QGKKFFV....................TQRVPD-----------RT-TI---LDLIKQNGG..
E3S9F7_PYRTT/19-96-GAKLF...........AGKKFFV....................AQRVPI-----------RN-HL---LDDIKSNGG..
G2QX03_THITE/15-91-VGSLF...........NGIKFWV....................SMRVPL-----------RS-ML---TSR.KDNGG..
E9CWR8_COCPS/8-85-PPALF...........NDLKFFL....................SATVPQ-----------RS-WC---ADLIKNHGG..
N1JJ21_BLUG1/13-90-CEKIF...........LNKKFFL...................LQKI.PD-----------RS-HI---KELITKRGG..
M5BM65_THACB/48-146-LSKLFVK.DVE..GEEESIRFYIVEWGDWD..................L-----------IA-DL---RGQITEYGG..
A7TGW3_VANPO/860-963-PILLF...........CNRRFFI.................PETLPS.TP-----------IY-EL---KSKVELYGG..
E3LW19_CAERE/691-776-PIQIF...........SHCRFFL...............ICSLSSHS.HL-----------CK-YV---GAIIRTNGG..
A7TIC7_VANPO/66-154-IAGIF...........QNLKFYI..............NTEQDAYDTVND-----------IE-TL---TRLIQSNGG..
G8C1X2_TETPH/45-136-NHSLF...........KGYSFFI..............NTKPDAYGKKSD-----------IN-SL---TRLALSHEG..
E7Q896_YEASB/122-207-SGPPL...........SNMKFYL..............NRDADAHDSLND-----------ID-QL---ARLIRANGG..
H2APC0_KAZAF/72-157-NSEPL...........VGMKFFL..............NRDSDAHDSIND-----------IE-QL---ARLIKSNGG..
G0VI01_NAUCC/119-206-ISTLF...........QGMNFFM..............NRNNDAHDSAHD-----------VD-QL---ARLIMAHSG..
C5DTR6_ZYGRC/67-154-QGLIF...........QGMSFYV..............NRDSSANDSAND-----------ID-RL---HQLVESRGG..
J7S744_KAZNA/61-148-KNKFW...........TGMRFFI..............NREDTAHDNVND-----------AD-RL---AALVTTYGG..
F2Z6A0_CANGA/80-168-EKGIF...........NGMVFYL..............NRDSNAHDSIII-----------VE-QL---KNLILLNGG..
I2GXL7_TETBL/69-154-KIGIF...........TGLSFYI..............PTEKTAYDSTLT-----------IE-QL---KDSLINNNA..
G0WD26_NAUDC/165-250-KKLVF...........ENIKFFI..............NRDSGAIDSSTE-----------AD-QL---ERLITANGG..
G8ZLB0_TORDC/16-100-EDGLF...........SGMRFYL..............NCGA...DSGAE-----------SR-QL---GDLIESRGG..
C5DD36_LACTC/53-131-QQDIF...........QDLGFFI.....................AHDES-----------RQ-EL---EQLVSGHGG..
D3BEV4_POLPA/10-104-NNDLF...........KSIVFYL..................IGVPI.GE-----------QN-KI---KTLLKKCGG..
F0Z8S8_DICPU/18-113-PIPIF...........RGINFYI..................MGLGF.SE-----------TT-QL---KALIKSYGG..
R0KT87_NOSB1/49-128-KKNVF...........KGLKFYI.........................K-----------DN-EI---GSLIEMYGG..
A8N1C0_COPC7/345-440-KLGLF.S.RNG.....APISFFI...................QIDH.AK-----------RN-SL---VQIVKTRGG..
B0CPN9_LACBS/390-485-KQGIFST.KEG.....G.LSFFV...................QIDL.GN-----------RL-RI---VTAIKKNGG..
V2XZF1_MONRO/81-173-SDVVFVT.QDG.....NPLTFFV...................QMEV.KN-----------RQ-TI---ISKIRKHGG..
F8PP65_SERL3/410-502-LGQTFLS.RSG.....RPFRFFV...................QVDL.QG-----------RH-GI---VMAIKRNQG..
K5W9L1_AGABU/439-532-TGSLFLN.EDG.....KPMQFYV...................QIDL.KG-----------RN-EI---LRAIKKNGG..
K5VDP9_PHACS/379-470-TPGLFVD.RKG.....RPIPIYV.....................QHAKW-----------RN-KY---VPDIQKFGG..
J4I894_FIBRA/337-429-DEEIFKT.DAG.....DSMMFYV...................QIET.RN-----------RG-EV---VQSIRKHGG..
M2QYA3_CERS8/374-465-GNNLFVE.D.G.....RALNFVV...................QIDT.RN-----------RK-EI---IQTVKAGGG..
A7RVV1_NEMVE/15-100-NSCLFLNDEDG.....SPILFYI....................TPG.PL-----------KK-RL---KTLIEVRGG..
B7QFB5_IXOSC/8-93-SRNLFTR.YDG.....GPMCFSL....................IPC.AE-----------RK-EI---REIIEYGGG..
E9HFT5_DAPPU/11-109-LSNLFRK.DSN....GEAIDFYL........RRTRL.GRQDNVEQD.EK-----------FK-KL---KEQIEKCGG..
E9HFT5_DAPPU/369-468-LNNLFRK.ESN....GDPIEFYM........RRTRFCHHENNLELE.GK-----------CS-KL---KEQIEKCGG..
F1REC1_DANRE/34-120-SPVLFLD.PGG.....QSMRFYV....................RPG.PT-----------KM-QL---HPLITSGGG..
W5K9C2_ASTMX/12-98-SPVLFLN.TKG.....EPMRFFI....................RPG.PT-----------KM-QL---QPLIQDCGG..
G3NA35_GASAC/14-100-SPVLFMT.VDG.....EPMTFFL....................RPG.PA-----------KL-KL---QPLITAGAG..
I3KA69_ORENI/14-100-SPVLFMT.VEG.....EPMNFFL....................RPG.PI-----------KR-KL---QPLISAGGG..
H2URR7_TAKRU/15-101-SPVLFMD.VDG.....QPMNFFL....................CPG.PV-----------KR-KL---QPLIVAGGG..
H3DBF1_TETNG/17-103-SPVLFMG.VDG.....KPMSFFL....................RPS.PA-----------KA-EL---QRLIVAGGG..
M4ASB2_XIPMA/13-99-SPVLFLT.VEG.....EPMSFFL....................RPG.PH-----------KQ-KL---QPLITDGGG..
F6WSD5_XENTR/10-90-SRTLFVD.DDG.....TPMSFYV....................PPG.PL-----------KR-QL---YPLITHGGG..
G5C0W9_HETGA/11-94-IPPLFVRADR......SPLSFYV....................QPS.PI-----------KR-WL---STVILHGGG..
H3AZ34_LATCH/10-93-SRTLFVR.EDG.....APVWFYL....................RPG.PA-----------KK-SL---APLIRHGGG..
TE2IP_CHICK/5-85-PRKVFVW.EDG.....TPMRFYI....................RPG.MA-----------KL-RL---APLLLAGGA..
W5N779_LEPOC/21-104-SVTLFVN.DVG.....SPMRFYL....................RPG.PA-----------KS-RF---AALIEAGGG..
B3RX95_TRIAD/6-86-NRNLF......QDADGKPMKFYI....................KPC.PT-----------KG-KV---RPLIESCGG..
H3H3N9_PHYRM/2-81-ASLLF...........RELRFYL.................TRTLSV.EA-----------KA-EL---KQLVEQNGG..
M4BMY6_HYAAE/1-80-MAPLF...........QHMQFYL.................SRTLSA.TD-----------RI-EL---KQLIEQEGG..
K3X8H7_PYTUL/34-113-SALLL...........RGHRFYV.................ARDIGQ.AR-----------RR-EL---QTLIKNNGG..
D2V2T9_NAEGR/8-105-TAKLF...........TSLCFFL.................SSSIPK.NE-----------KE-KL---IKSIEKHDG..
K0KC61_WICCF/18-95-DQALL........NQNEPIQFFI...................PINE.DD-----------RD-NL---EKLIIDHGG..
K1VGF5_TRIAC/277-367-SPDLFCD.HDG.....SPLRFHL.....................DD.DS-----------RA-EM---AMSILDHGG..
I7MFY6_TETTS/273-374-LTDLL...........ENLRFYI.............SEKQTKKDQQ.IT-----------KK-EM---VQLIKLAGG..
D8M843_BLAHO/73-162-CTQLF...........AGFSFYF..................DGFLGEKT-----------RL-EL---VELVRAHGG..
D1ZZU6_TRICA/469-555-LPGFL...........DFKTFFI..................DECLDEDV-----------AK-TL---ERYIIAYNG..
F1N2F9_BOVIN/552-641-LPDFF...........QGKRFFL.................YGEFPG.DE-----------RR-TL---SRYVTAFNG..
H9G8R9_ANOCA/562-651-LPDLF...........EGKHFFL.................YGEFPS.NE-----------RR-LL---NRYIIAFNG..
G4VGJ3_SCHMA/541-631-LPDIF...........MNKNFFI................HNKSIPD.DE-----------ES-LI---KRLIVAFGG..
A0A068XE55_HYMMI/504-594-LPDIF...........SGKKFYI................FSKDIVL.KE-----------EE-TV---YRLIITFGG..
H2ZBQ2_CIOSA/420-509-LPNYF...........SNVSFYI.................LGDFTP.AV-----------KR-ML---QRHIIAFGG..
W5JUY9_ANODA/538-620-GLDFF...........KDYIFFI.................DRGVGA.VD-----------TM-KL---ERFIKTYKG..
F4PQL1_DICFS/4-97-QFLSF..............HFYI................HPNINKE.YK-----------RC-KV---EQVIRHLGG..
K1PXK2_CRAGI/835-912-PQLLF..........SSMGVFYV...................TPKAVPP-----------RH-HL---MELIQRCAG..
Q5KDC9_CRYNJ/1333-1431-GAGLFTV.AGA.....VPLSFWV....................YGG.SR-----------AR-TL---EIVITHAGG..

PF16759

H2ZXR2_LATCH/884-956TLLDIF-----------TGVRLYL-------------------PPSV.ED-----------FS.KL---QRYFIAYDG--
F6S783_MACMU/933-1005VLLDIF-----------TGVRLYL-------------------PPST.PD-----------FS.RL---RRYFVAFDG--
D2W3T0_NAEGR/824-906SLCDLF-----------TDMVMYI-------------------HKDV.PA-----------LK.MH---TRYIIAFDG--
H3CY38_TETNG/809-881TLLDIF-----------SGVKLFL-------------------PLTV.QD-----------FD.KL---RRYFVAYDG--
G3QCE5_GASAC/909-981TLLDVF-----------SGVKLFL-------------------PVSV.QD-----------FH.KL---RRYFVAYDG--
Q1RL58_CIOIN/781-858FLNDIF-----------LGVKIFI-------------------PTDV.EK-----------RK.KM---ERHILAFNG--
E0VGK6_PEDHC/807-896PLPNIF-----------TGCVIQI-------------------PKEY.KN-----------YD.LL---RRYLIAYDG--
H0Z3J4_TAEGU/853-925PLLDIF-----------TGVRLYL-------------------APSV.KD-----------FD.RI---RRYFIAFDG--
H2MK50_ORYLA/283-355TLLDIF-----------GGVKLFL-------------------PASI.QD-----------AD.RL---RRYFVAYDG--
C3XPG8_BRAFL/848-925VLPDVF-----------CGIKLFL-------------------PDTV.EN-----------YA.LL---RRYFVAYDG--
D6WBL1_TRICA/353-434SIPNYF-----------ENVRLFL-------------------EEGVKER-----------HA.QW---VKYFIAYGG--
F2US92_SALR5/1151-1238PLKNVF-----------HGVTCFI-------------------SDAV.PD-----------YS.KA---YRYGTAFGA--
D6WBL2_TRICA/760-840PLPDYF-----------HNIKVVL-------------------EDKVREK-----------QW.DL---IRYFIAYGG--
H2Z1K6_CIOSA/772-849FLKDTF-----------EGVKIFI-------------------PNDV.QN-----------RS.KM---VRYIKANNG--
A0A0D2X4A3_CAPO3/1228-1306.LPDTF-----------VGTNILL-------------------SPQLSPD-----------VKRRL---QRYIVAYGG--
F6WXI9_XENTR/905-977TLLDIF-----------TGVKLHI-------------------PSTL.DD-----------FA.KL---RRYFIAFDG--
J9JUI3_ACYPI/779-867RLPDLF-----------TGIRVVV-------------------PDSI.SK-----------NT.FL---.RYFIAYGG--

PF16770

Q0TZK5_PHANO/609-711APARNKRAKKDKLTP--IKFRMLV-------------------SKDERWTNNDE.......KASKE---KAKLRELGL--
C4R1B3_PICPG/699-801QDSAVVETEVILPSK--YSLHAIT-------------------TGCTIT............LSKVH---LKKLSTVGI--
G2QHK9_THIHA/602-704ENKRPAKRAKVSLPE--VDMRICL-------------------TGYKRWVENKG.......AEEAD---RRKLRSLGI--
M3JFE1_CANMX/645-749TTSETTTTPIKKPTQ--YKTIAMM-------------------TGCESEIS..........LEDPD---ISKLQTLGV--
E9CRG1_COCPS/597-699TTDTETKKQKKTRPQ--VSMHLLI-------------------TGYSPWVGNAR.......QEDND---RRILRDLGI--
M2M1A3_BAUCO/659-760GKKAKTAAANVSLPP--VMFRMMT-------------------TGDDRWHGNLK.......QEDVD---KTKLRMLGV--
G4NCT3_MAGO7/597-703DGERPAKRQRSSRPP--VQYRICL-------------------TGWKRWLAPDVKSVS...QEDKE---RRKLRQMGI--
F2SLK3_TRIRC/597-699EDAIETKRIKTSKPP--IAIRLVI-------------------TGFNRWVEKPN.......IEDSE---RTQLRDLGI--
R8BK69_TOGMI/621-723EARRPAKRQKPSLPP--VEMKICL-------------------TSFKRWTGDRN.......KEDND---RRKLRSLGI--
S3D3M8_GLAL2/608-712RQRLSLDKKKPKTVP--IEVQLVV-------------------TGYSGWVNNVA.......KEDSD---KKKLRELGI--
C7YM63_NECH7/596-698AAKRPAKKARQSLPD--VEMRVIL-------------------TGFSRWVGDKN.......KEDQD---RRKLRDLGI--
C4JTM0_UNCRE/600-702ISDTESKKQKRVRAP--VSMHLLV-------------------TGYAPWVGNWK.......KEDSD---RRHLRDLGI--
C8V3U9_EMENI/593-695EDTTEAKRQKKSKPP--ITMHLLI-------------------TGYQRWVGNMK.......KEDAE---KRQLRELGI--
Q6BZF3_DEBHA/634-743KAKKRKTESPRPDTD--TKIVAVI-------------------TGCENEIT..........LTRQD---TQNLNHIGV--
I1RVV5_GIBZE/601-703TAKRPAKKAKPTLPG--VTMRVIL-------------------TAFNRWVGDKA.......KEDRD---RKKLREMGI--
L8WY45_THACA/745-841PKASEDVKAQKPIMK--SPVRIVC-------------------SKSK..............PTESE---IKQMERLGA--
C5DS98_ZYGRC/912-1023TGSEGAQHHRSKKLP--YNINAVT-------------------TGLSGN............IGELD---LTILRLLGI--
K5WLU5_PHACS/1099-1194AKAKPEASTSADSRD--KGVVIMT-------------------TQVT..............LTEDQ---NKALMKLGA--
Q75AR5_ASHGO/635-742PYLEEYSDTTGGRLP--YDIKAVF-------------------TNCHEN............ITDLD---KEILRQLGI--
B6K613_SCHJY/586-680SRHSVQQHSSTTQLR--KKYRVMF-------------------TGS...............SPRTP---SNELKLVDI--
G0W9V9_NAUDC/944-1052LFDHLSKAAFLHLPL--YDIDAIP-------------------TNCLED............ITPFE---TKVLNRLGI--
I2GZK5_TETBL/782-893IDLLFSKKSPKSCLP--YNIEAVC-------------------TGCPEL............NNELE---LHILKRLGI--
N1JBZ0_BLUG1/603-705QAPRTAKRARVGPPP--VEIRLII-------------------TGYKKWVQNLP.......KENAD---TKKLRQAGV--
E9EQX4_METRA/605-707DTKRPSKKQRPSLPD--VHMRLVV-------------------TGYTGWVGDSK.......KEDQD---RRKMRALGI--
G3MZP9_BOVIN/976-1073RIEDIPPPTKKLTPE--LTPFVLF-------------------TGFEPV............QVQQY---IKKLYILGG--
Q6CN34_KLULA/656-761KADEMVSYLNISHKP--YKIKAVL-------------------TNCHEN............LSNLD---ILILSKIGV--
L2GJC4_COLGN/595-697DERRPTKKRKSAGPE--VEMRVVL-------------------TGFTRWVNNKH.......KEDVE---RRKLRDMGI--
T5A5F6_OPHSC/606-708EAKRPAKKARPSMPE--VNMRIVV-------------------TGFARWVGEKK.......NEDSD---RRKLRDLGI--
N1Q1B5_DOTSN/497-598QNKKAKHAPSSTLPP--VKYRMMV-------------------TGDDRWTNNAK.......KEAAD---KAVLRGLGV--
L0PC51_PNEJ8/4-94TPRTKFSAANKNSQD--YDIRILV-------------------TGYKDWNNQTEKVSQSIRKHD..---.........--
G3AMT0_SPAPN/577-678LLSSPPVKKHKPNKK--CEIIAVM-------------------TGCESIID..........LSADD---IANLQNVGV--
I2H240_TETBL/888-996LCSVTHTNIPLKRYP--YNINAIC-------------------TGYEEN............YTDLE---LCLLRLLGI--
C5M5V1_CANTT/627-732SEDEIEVLEENKVVE--FDIIGIM-------------------TGCESEIE..........LNKQD---HEHLKNLGI--
G8BF53_CANPC/627-730ADVDSSDLKRPRTDE--CSIIAIM-------------------TGCEQDIE..........LSKSD---YTKLQSIGI--
A5DUV3_LODEL/733-836DILEMKEHKRQRTNE--CDIVAIL-------------------TGCELQIN..........LTKND---CAKLQTVGI--
H6BTR1_EXODN/609-711DSEPESKKVKRGTPT--PLMHLVI-------------------SGYTKWVGHPR.......IEDND---KKQLRGLGI--
A7TEV9_VANPO/803-912VLRCMDGSQSTEENI--YNIRAVC-------------------TGCLDK............INEID---LVILRLIGI--
D5G6X4_TUBMM/591-693EDSRTDNKKQKKRPR--PTVYLLM-------------------TAYRDWVNQPH.......REDTD---RKALADLGI--
J3P060_GAGT3/622-731DSERPTKRARPSQPP--VQYRIMI-------------------TGWTRWIDTGDKTKGGALQEDKE---RRKLRQMGI--
G1X016_ARTOA/638-741EKPKKQKKKSMEKVV--ISVYLLL-------------------TSHQAWIDRPS.......REEND---KRALREIGI--
J7R641_KAZNA/728-836STVESETFLKTVRHT--YSIVAYI-------------------TGCLDD............MTALD---KAILKLVGI--
A5DNV2_PICGU/524-631ERATESPPPKKKKAV--TNVNAII-------------------TGSEDEIT..........LSRSD---LAKLSQVGI--
BRC1_SCHPO/650-744SRESSESRNTNAKAS--KRVYITF-------------------TGY...............DKKPS---IDNLKKLDM--
G0S8X0_CHATD/601-703QDKRPAKRAKTSLPE--ADMRICL-------------------TGYKRWAGDKS.......SEEAD---RKKLRALGI--
B6K1B2_SCHJY/418-515SFSPQKLLRELQASS--SLVVAIV-------------------TGYTSP............FSKDF---LQRLRKLGI--
R7YHQ6_CONA1/603-705PKKAKKARGAKNQPP--IQYRLML-------------------SGDDRWVDKPG.......KESAD---KIKLRDIGI--
S6EZG3_ZYGB2/878-989KSQTPSQHTPRKRLP--YHINAVH-------------------TGGHND............INELD---LVLLRLIGI--
C5DDJ9_LACTC/677-784LETVAGRPKGKSMKP--YDIIAVC-------------------TGCHEE............IDEFD---LELLRRVGV--
RT107_YEAST/820-925TKAEKILARFNELPN--YDLKAVC-------------------TGCFHDG...........FNEVD---IEILNQLGI--
T1K2U0_TETUR/823-921PPLMVAPFANASPDR--AAVKVMF-------------------TGFNDAS...........TLAEL---KEYAKKLGL--
M7T0V6_EUTLA/570-672SEKRPAKRAKPSLKE--VEMRVVL-------------------TGFKRWVNDKH.......KEDAD---RKKLRELGI--
S3BRI5_OPHP1/687-789DQARPAKKSRPSLPS--IQMRVVL-------------------TGYHRWVNSST.......KEETE---RRKLRSLGI--
G3AYG3_CANTC/572-676SKKQKAFTPEKTASQ--LSMVAIM-------------------TGCESEVD..........LTRED---IANLKNYGI--
G8YB77_PICSO/622-730DAPKNKKRKVEETRP--YDVKGIV-------------------TGCEGILT..........LSKQD---LSSLKDIGI--
F0U567_AJEC8/604-706EDTNGVKKPKQAPVP--IVMHLLL-------------------TGYRKWVGDLK.......SEESD---RRKLRNLGI--
S9VT84_SCHCR/649-743PEKQANQNIPNTNLK--ERRYVVI-------------------TGY...............ETKPS---SDDLKKINI--
W1Q8C3_OGAPD/435-537SLEMPRKKAKPNSKP--YNIVAIL-------------------TGCDKE............FSASD---LRNLNKVGI--
G2YB22_BOTF4/618-722DVRPSKKAKTASKPE--VQVRMLV-------------------TGYKAWSNPDAPT.....KEDTD---TKKLRSLGI--
M7PGB1_PNEMU/569-665KTIAKFFPTNKDFRD--YSVRILV-------------------TGYKDWDNQME............---.KALLTIGI--
M1VXB8_CLAP2/609-711EKKRPAKKPRPSLPD--VQMRIVI-------------------TGFNRWVGDSN.......KEDHD---RRKMRDLGI--
N1QC64_PSEFD/642-743KQKKAKTAASPRLPE--VKYKMMV-------------------TGDDRWVENTR.......KENAD---KSILRQLGV--
Q5ALY1_CANAL/652-759ELSQSDFLKTKKKTQ--YHIIAIM-------------------SGCEQIIE..........LSKSD---IQKLRTIGI--
G2WSE1_VERDV/588-690AEKRAAKRRRSSKPD--GVIKVML-------------------TGFSRWLNDKH.......KEDVE---KRKLRELGI--
G0VDU3_NAUCC/653-763KDAKEILSKIVIDKK--FSIVGTC-------------------TGCHED............ISKLD---LEILRLLGV--
F9X0T3_ZYMTI/525-626LTKKAKHAAVPDLPE--VRYRMMV-------------------TGDDRWASNAR.......KESAD---KNTLRSLGV--
Q6FR08_CANGA/839-955NPYTCNSSNQTISLN--IGLNAIC-------------------TGFSLED...........LTDIE---KEILRLVGI--
H2AVG7_KAZAF/692-804REILSGIFQESPSKI--FNLNCLC-------------------TGCHEE............ISELD---LELLKLLGV--
G8JP23_ERECY/643-750HVDISKGSKGRQKLP--YDIKAVC-------------------TSCHDD............ISELN---LEILKQIGI--

PF12738

MCPH1_HUMAN/9-75-KV-------------------------SK--------------TF.NKQ-------VTHVI----F...KDG-------
ECT2_MOUSE/179-242-VI-------------------------RK--------------EC.NSK-------VTHLV----A...NCT-------
A2R3M9_ASPNC/121-184-EF-------------------------RK--------------DL.TKN-------VTHLI----A...RNT-------
A7F1C2_SCLS1/119-182-EY-------------------------DG--------------NL.TKQ-------ITHLI----S...FRT-------
A7S5M3_NEMVE/449-511-NY-------------------------TG--------------YL.MRT-------NTHLV----C...RSS-------
A9RB53_PHYPA/468-530-KF-------------------------SE--------------TL.NSK-------ITHLL----C...KVQ-------
B0DMV8_LACBS/502-564-VI-------------------------PP--------------VF.SKK-------ATHLL----C...PSG-------
B2VU23_PYRTR/350-412-EF-------------------------TK--------------TF.KQE-------NTHLI----A...AHK-------
B2W796_PYRTR/229-291-KI-------------------------SD--------------NV.RID-------TTHFV----C...TEG-------
B2W7P6_PYRTR/114-177-EY-------------------------HG--------------DL.TKS-------VTHLI----A...ATP-------
B3RL44_TRIAD/702-764-NY-------------------------TP--------------HL.SRK-------NTHLI----C...KSP-------
B4H593_DROPE/186-250-QI-------------------------ND--------------RL.LRN-------TTHVI----F...KDG-------
B4KSD3_DROMO/76-140-QA-------------------------ND--------------RL.LRN-------TTHVV----F...KDG-------
B6HL54_PENCW/128-191-EY-------------------------RK--------------DL.TKT-------VTHLI----A...RNS-------
B6Q6C3_PENMQ/111-174-EF-------------------------RK--------------DL.TKT-------VTHLI----A...QQA-------
C0NFA4_AJECG/121-184-EF-------------------------RR--------------DL.TKS-------VTHLI----A...RSG-------
C1FFW2_MICSR/561-624-KY-------------------------TE--------------RLGRNK-------NTHLV----V...PYA-------
C4M4C9_ENTHI/17-80-IY-------------------------ME--------------DMESRS-------VSFLL----S...KGL-------
C5FMN4_ARTOC/111-174-EF-------------------------RK--------------DL.TKT-------VTHLV----A...RVG-------
RAD4_SCHPO/105-167-TF-------------------------CP--------------DL.TRD-------VTHLI----A...GTS-------
Q16W28_AEDAE/219-283-KV-------------------------ND--------------KL.YKD-------TTHVI----F...KDG-------
Q1K5Z2_NEUCR/339-401-TY-------------------------TK--------------TM.KAD-------NTHLI----T...ARM-------
Q2H787_CHAGB/324-387-LY-------------------------TG--------------DL.TKQ-------VTHLI----V...YKP-------
Q4CP92_TRYCC/1-63-TY-------------------------VA--------------EL.TTS-------TNVLI----A...GRS-------
A0A0D1CFS9_USTMA/599-667-SI-------------------------IT--------------HWKAES-------LTHVV----CATQESF-------
Q5TRD6_ANOGA/110-173-SI-------------------------RK--------------GM.DTK-------VTHLI----C...NSS-------
Q6CN34_KLULA/351-414-IC-------------------------ST--------------EL.TKK-------NTHLI----S...PIA-------
PAXI1_MOUSE/102-165-SC-------------------------QL--------------NL.NKK-------CTHLI----V...PEP-------
Q6Z553_ORYSJ/10-72-SY-------------------------VG--------------AM.SRS-------ITHLV----C...WRL-------
Q9U7D8_DROME/117-180-CI-------------------------KK--------------DL.NTK-------TTHLI----C...NHS-------
B9GSH3_POPTR/111-175-HF-------------------------SK--------------PLVANR-------VTHLI----C...YKF-------
D7SMI0_VITVI/4-66-KY-------------------------VG--------------TM.SRS-------ITHLV----C...WKF-------
F4I701_ARATH/188-251-SY-------------------------SA--------------EL.TKS-------CTHLI----A...DAA-------
F4I701_ARATH/667-729-DF-------------------------VE--------------RL.TRK-------VTHLI----C...NFA-------
F6XFW7_XENTR/204-267-EY-------------------------TG--------------QLKMNE-------STHLI----V...QEA-------
H0ZRM8_TAEGU/5-67-EV-------------------------SK--------------TL.NKH-------VTHVV----F...KDG-------
H3C8W0_TETNG/80-141-RY-------------------------TG--------------YL.CRS-------NTVLI----C...KEP-------
I1QYC0_ORYGL/209-271-QY-------------------------SA--------------NL.TRR-------CTHLV----S...NEP-------
I1QYC0_ORYGL/675-736-KF-------------------------TE--------------KA.TKK-------VTHLI----C...KFA-------
Q4WQC2_ASPFU/345-407-EC-------------------------TK--------------TL.KQE-------NTHLV----T...AHG-------
Q7JUM5_DROME/187-251-QV-------------------------KD--------------RL.TRT-------TTHVV----F...KDG-------
U5GIH0_POPTR/4-66-SY-------------------------VG--------------AM.SNS-------TTHLV----C...WKF-------

PF00533

Y4211_ARATH/1089-1168-KCC......................RDSH--------------QW.SYQ-------ATHFI....A---PEI.......
MDB1_SCHPO/384-455-RV.........................QE--------------SV.TDE-------TDFVI....L---GSP.......
MDB1_SCHPO/485-573-EIV......................GDIK--------------RA.QEK-------DTIIL....A---QPDN......
ECT2_MOUSE/266-341-SY.........................LP--------------VG.DER-------CTHLI....V---EEN.......
PAXI1_HUMAN/701-776-KY.........................TG--------------YL.CRS-------NTVLI....C---KEP.......
PAXI1_HUMAN/860-934-EV..........................A--------------ES.AQK-------CTHLI....A---SKV.......
TDT_HUMAN/27-111-RV.........................EN--------------EL.SDS-------VTHIV....A---ENNSG.....
RAD9_YEAST/994-1109-TVIESGFSTLFNF..THPLAKSLVNKGNT--------------DN.IRE-------LALKL....A---WKPHSLFADC
XRCC1_HUMAN/538-616-EL.........................ED--------------NM.SDR-------VQFVI....T---AQE.......
Q93161_CAEEL/981-1063-IT.........................SD--------------EA.NSN-------TTHVI....V---KTDEN.....
PARP4_HUMAN/1-81-KF.........................SF--------------SL.NPQ-------CTHII....L---DNA.......
TOPB1_HUMAN/101-176-RV.........................YR--------------DL.NVS-------VTHLI....A---GEV.......
TOPB1_HUMAN/195-271-QY.........................MG--------------QLKMNE-------CTHLI....V---QEP.......
TOPB1_HUMAN/354-431-VR.........................FN--------------QL.NED-------VTHVI....V---GDY.......
TOPB1_HUMAN/548-620-KI.........................MS--------------LL.SRT-------VADYA....V---VPL.......
TOPB1_HUMAN/641-725-SVQEYF................VRKSNAK--------------KG.MFA-------STHLI....L---KER.......
TOPB1_HUMAN/900-978-DY.........................RW--------------SF.DET-------VTHFI...YQ---GRP.......
TOPB1_HUMAN/1260-1338-LVI.......................EKQ--------------CF.DPT-------CTHIV....V---GHP.......
Q20129_CAEEL/451-529-TR.........................VA--------------KF.TSA-------TNVVV....V---SPN.......
Q20129_CAEEL/587-659-KL.........................MD--------------DP.DYA-------EFVIF....G---HSG.......
Q20129_CAEEL/679-749-RI.........................VE--------------QL.EPK-------DFIIM....I---DAE.......
DNLJ_HAEIN/592-668-KV.........................SG--------------SV.SSK-------TDFVI....A---GDA.......
DNLI4_CANAL/673-756-KI.........................VN--------------SV.DLA-------TNYQI....M---VIT.......
Q20129_CAEEL/128-204-VV.........................GD--------------AL.YHE-------TTHLV....T---EKA.......
O76369_CAEEL/929-1023-TALHVAV...............RKAHTSD--------------EQ.MST-------TTHCV....V---KTNEN.....
PAXI1_MOUSE/588-668-TV.........................DP--------------TF.TSR-------CTHLL....C---ASQ.......
PARP1_MOUSE/385-463-KL.........................TG--------------SA.NKA-------SLCIS....I---KKE.......
DNLI4_HUMAN/654-730-YI.........................VQ--------------NP.GPD-------TYCVI....A---GSE.......
DNLI4_HUMAN/814-898-KV.........................VS--------------CL.AEG-------VSHVI....I---GEDH......
O16568_CAEEL/1044-1144-SV.........................VQ--------------DI.EAD-------DEKTPKPYWT---LSSFYKKKKW
TDT_MONDO/27-111-RV.........................EN--------------EL.SNS-------VTHIV....A---ENNSG.....
O16229_CAEEL/378-460-IT.........................SD--------------EA.MLT-------TTHVV....V---KVNPA.....
DNLJ_HELPY/577-652-KI.........................SS--------------SV.SAK-------TDFLI....A---GEN.......
DNLJ_BACSU/590-666-KL.........................TG--------------SV.SKN-------TDLVI....A---GEA.......
DNLJ_MYCLE/607-683-KV.........................AG--------------SV.SKK-------IAYVV....V---GDL.......
O44844_CAEEL/154-256-TCSM....................SPIPG--------------EA.GKI-------PYHLV....K---RNLKVPSASI
DNLJ_BORBU/583-659-IF.........................NT--------------CV.TGS-------LDFLI....V---GEK.......
BRCA1_RAT/1588-1669-AL.........................TD--------------VI.TEE-------TTHVI....I---KTDAE.....
BRCA1_RAT/1701-1787-SVVK....................ELPLL--------------TR.DTG-------AHPIV....L---VQPS......
RFC1_SCHPO/236-313-KV.........................TG--------------AP.SVR-------TDFIL....L---GEN.......
DNLJ_AQUAE/619-696-KF.........................SN--------------SV.TSK-------TDYLV....V---GKD.......
CHS5_CANAL/164-246-KY...........................--------------.P.VQQ-------QVKVD....T---THFLC.....
DNLJ_TREPA/562-642-VV.........................RT--------------SV.TRD-------LSYLIFESLS---QPY.......
DNLJ_CHLTR/581-657-KV.........................SS--------------SV.SKS-------TYAVI....A---GSE.......
O96271_PLAF7/208-298-SV.........................MT--------------AV.STK-------TNYLV....H---GEY.......
PESC_LEIMA/317-390-RV........................ATD--------------YV.PSN-------ITHVV....V---DRPA......
DNLJ_ECOLI/593-669-KV.........................AG--------------SV.SKK-------TDLVI....A---GEA.......
PARP1_CHICK/382-460-KM.........................TT--------------TA.NKA-------TLCIS....T---QKE.......
DNLJ_THET8/589-664-KV.........................TD--------------SV.SRK-------TSYLV....V---GEN.......
DNLJ_ZYMMO/645-721-KV.........................AS--------------SV.SKK-------TNLVV....A---GEA.......
RAD4_SCHPO/2-79-AY.........................RS--------------DF.TKD-------VTHLI....A---GDF.......
RAD4_SCHPO/392-473-VV.........................HE--------------FL.GVQ-------RSILL....V---NTNEP.....
RFC1_DROME/232-309-KV.........................MT--------------VV.GKK-------LKYLV....V---GEE.......
TDT_CHICK/27-111-RV.........................ES--------------EL.SDS-------VTHIV....A---ENNSY.....
BRCA1_HUMAN/1642-1723-TL.........................TN--------------LI.TEE-------TTHVV....M---KTDAE.....
BRCA1_HUMAN/1756-1842-SVVK....................ELSSF--------------TL.GTG-------VHPIV....V---VQPD......
RFC1_YEAST/153-230-RV.........................TK--------------SI.SSK-------TSVVV....L---GDE.......
RT107_YEAST/2-103-NNC......................QIYE--------------LY.NEN-------LKDVK....T---DKDWFMNKFG
RT107_YEAST/117-213-TL.........................VN--------------YI.SNR-------TTHVI....V---QSPQDPIIAT
RT107_YEAST/261-352-KV...........................--------------......-------TPLSF....S---DDLKSVYQAF
RT107_YEAST/370-453-LS.........................TP--------------EL.TRK-------NTHLITKSTI---GKK.......
YPT4_CAEEL/930-1012-IT.........................SD--------------EA.MIT-------TTHVV....V---KTTED.....
YPT4_CAEEL/1049-1141-TM...........................--------------.L.DKF-------PDKDA....F---NKGSHPYLHK
DPB11_YEAST/111-207-SSYNYQNFVIK.......DTSSHNDDDDQ--------------GQ.NGQ-------ISIFV....T---DTL.......
DNLJ_SYNY3/591-667-KV.........................TS--------------SV.STK-------TDYVL....L---GDK.......
RHP9_SCHPO/535-640-LVLDTGLRPLFNDPFKSKQKKLRHLKPQK--------------RS.KSW-------NQAFV....V---SDT.......
FCP1_YEAST/499-580-TS.........................TP--------------DI.DYL-------TTHLI....T---KNP.......
DNLI4_YEAST/681-767-KLIY....................NVILK--------------RH.SIG-------DVRLI.....---..........
DNLI4_YEAST/836-928-KI...........................--------------...TDQ-------QSLCN....L---IIIPYTDPIL
Q09615_CAEEL/251-326-EY.........................HC--------------YY.QHG-------ITSYT....I---ASS.......
BRC1_SCHPO/14-91-AL........................SFP--------------YD.WKL-------ATHVI....C---DDF.......
BRC1_SCHPO/105-183-RF.........................SK--------------GL.MKS-------MTHLF....T---YSG.......
BRC1_SCHPO/216-293-KI.........................AE--------------SI.NDC-------DIFIG.....---..........
BRC1_SCHPO/311-386-TY.........................TK--------------DL.KPT-------NTLLI....A---ASS.......
CHS5_YEAST/166-249-R............................--------------.P.LQR-------HVAID....T---THFVCN....
XRCC1_MOUSE/315-390-KY.........................RP--------------DW.TPD-------STHLICAFA.---..........
Q94046_CAEEL/514-600-DIEFE...................ASKFH--------------ER.IHQ-------ITHVL....V---DSC.......
Q94046_CAEEL/620-694-KI.........................TP--------------FL.ARQ-------NDLLI....A---KQP.......
DNLJ1_STRCO/643-719-KV.........................TG--------------SV.SKK-------TSFVV....V---GDN.......
DNLJ_RICPR/610-686-KV.........................TA--------------SV.SLN-------TDLVI....A---GVN.......
PARP1_ARATH/394-471-EF.........................HA--------------NV.KKG-------TSCLV....V---CGL.......
D0MI04_RHOM4/636-709-RV.........................AS--------------SV.SRN-------TDYVV....V---GEN.......
H9KXM3_CALJA/403-478-KV.........................TG--------------NV.SKK-------TNYLV....M---GRD.......
Q5AZH7_EMENI/325-400-KV.........................TT--------------AP.SGK-------TSFVV....L---GSD.......

PF16589

K3WDG2_PYTUL/626-709.EI......CNQI.................--------------..-SVA----...DMVIC----G---DG........
A2GB92_TRIVA/56-149VMM......VCTS.................--------------..-...----...VTHVI----A---EH........
E4V0Q5_ARTGP/707-798.KI......YQTN.................--------------..-T..----.....A..----.---..........
H6BN77_EXODN/749-843.RI......VQTH.................--------------..-T..----.....V..----.---..........
D7MMS2_ARALL/654-741.KF......SMNL.................--------------..-NNS----...VTHCI----A---AE........
D7SQI2_VITVI/653-740.TF......SMNL.................--------------..-NNS----...VTHCV----A---AQ........
M0S2G9_MUSAM/640-728.TF......SMNL.................--------------..-NDS----...VTHCI----A---AE........
K7LC24_SOYBN/506-593.TF......SMNS.................--------------..-NNS----...VMHCV----A---AD........
Q5KPS9_CRYNJ/138-224YPV...........................--------------..-LRN----KTMVDYII----A---PVLTLKKHEE
A8WS89_CAEBR/455-544.TR......VAKF.................--------------..-ESA----...THVVV----I---NP........
H2ANJ1_KAZAF/685-782.KI......SHNI.................--------------..-VSK----...RES..----.---..........
I1BS31_RHIO9/47-133.EC......VQKAESANILIAGNKTFHVIS--------------LI-NSG----........----.---..........
I2H6P9_TETBL/707-804.RV......IYNV.................--------------..-IAK----...TYT..----.---..........
D2V2T9_NAEGR/209-297.KVLQSRLLKDNV.................--------------..-KID----...YLITR----Y---AC........
D8M2G5_BLAHO/342-422.RV......AATL.................--------------..-DDA----...VYVVC----A---KT........
G8BNV8_TETPH/119-211.YV......TDIL.................--------------..-SSK----...VTHVV----A---ES........
M2N998_BAUCO/197-300.RL......SIAL.................--------------..-GRR----S..VTHVI----I---ARPSSNG.GC
M2ZQ43_PSEFD/117-220.NM......SIAL.................--------------..-GRR----T..VTHVI----L---GKPNANGSGC
V4Z6W2_TOXGO/178-272.RI......CMLF.................--------------..-GKG----...CTHII----A---ET........
A3LW54_PICST/41-121.VL......LDHSVTDCFWLSTNPLT....--------------..-...----........----.---..........
G3AM46_SPAPN/45-124.VV......TDRL.................--------------..-IPS----...CYFLS----N---NA........
M3K224_CANMX/72-151.LL......VDKQ.................--------------..-IPT----...AYHLS----N---NE........
Q59XT2_CANAL/89-168.VI......VEKG.................--------------..-FPT----...VILLS----N---NE........
A5DYD1_LODEL/66-146.FI......TEGG.................--------------..-VEN----...VIYLT----S---HT........
G8BJX2_CANPC/111-190.YL......AEGE.................--------------..-VDG----...IVCVT----S---KS........
C4R0P7_PICPG/22-117.TL......IDST.................--------------..-DDP----...LTLFL----A---ES........
C4VBY8_NOSCE/44-123.VL......TDDI.................--------------..-TKC----...TYVLT----H---KT........
R4XAV8_TAPDE/3-87.VL......VHSELMNNIIKIGDPAKPQSY--------------..-...----........----.---..........
A7EAG9_SCLS1/12-89.EV......TKFE.KKAQIIIADG.ARK..--------------D.-APP----........----.---..........
G2YA12_BOTF4/12-89.EV......EKLE.KNAENIIADH.MRK..--------------D.-APP----........----.---..........
E3QRM6_COLGM/14-92.KI......VKTDTNKADIIIADH.PRP..--------------E.-YPS----........----.---..........
H1V395_COLHI/14-91.KI......VKLD.KQADMVIADH.VRP..--------------D.-CPL----........----.---..........
L2G6F7_COLGN/14-91.KI......VKLD.KHADLVIADH.VRR..--------------D.-CPP----........----.---..........
E3S9F7_PYRTT/19-96.QI......VLLE.KQADYVIADH.FRR..--------------D.-CPP----........----.---..........
G2QX03_THITE/15-91.NI......VLLE.KHADVLIADH.ARK..--------------D.-TPA----........----.---..........
E9CWR8_COCPS/8-85.KV......VPLE.KNADILLVDHMKKD..--------------..-LPP----........----.---..........
N1JJ21_BLUG1/13-90.EV......VKVE.................--------------..-EQA----...DLIIA----D---HN........
M5BM65_THACB/48-146.EV......VEER.................--------------..-PIE----...GYCLV----D---PR........
A7TGW3_VANPO/860-963.KL......VNKI.................--------------..-SDC----...NVIVF----T---NT........
E3LW19_CAERE/691-776.AV......IDEM.................--------------..-DSK----...AYKIM----I---TK........
A7TIC7_VANPO/66-154.TVLENIPQQNSI.................--------------..-...----DFSKFFVI----S---PY........
G8C1X2_TETPH/45-136.TILDELPDSTSM.................--------------..-TGE----QRSKFYVV----S---PY........
E7Q896_YEASB/122-207.EVLDSKPRESKE.................--------------..-...----...NVFIV----S---PYNHT.....
H2APC0_KAZAF/72-157.QILEDVPQSAKT.................--------------..-...----...NVVIV----S---PYNDT.....
G0VI01_NAUCC/119-206.NVLASLP.EDTT.................--------------..-...----DVSNVYVI----S---PY........
C5DTR6_ZYGRC/67-154.TVLHEMPIKELI.................--------------..-GP.----...GVFIV----S---PY........
J7S744_KAZNA/61-148.ELIDEVP.DSTD.................--------------..-...----QDGKALVI----S---PY........
F2Z6A0_CANGA/80-168.DIVNKLPNKDSA.................--------------..-...----EAKHIIVV----S---PY........
I2GXL7_TETBL/69-154.IILNQLPSQDSV.................--------------..-...----...DSFVI----C---PY........
G0WD26_NAUDC/165-250.EIVKALPQQASS.................--------------..-...----...DFFVV----S---PY........
G8ZLB0_TORDC/16-100.EVVDKLP.EDVK.................--------------..-...----EGEKLYVV----A---LY........
C5DD36_LACTC/53-131.TVLSELPSGKSN.................--------------..-...----...KEFVV----S---TI........
D3BEV4_POLPA/10-104.SI......ALQV.................--------------..-NKS----...VHYLI----T---TT........
F0Z8S8_DICPU/18-113.DV......AFQI.................--------------..-NKN----...VKYLL----I---SK........
R0KT87_NOSB1/49-128.KL......VKNI.................--------------..-KKC----...DFYLE----K---KY........
A8N1C0_COPC7/345-440.TI......VADV.................--------------..-KEA----...DFAIL----Y---SA........
B0CPN9_LACBS/390-485.KI......TNNH.................--------------..-TTA----...DYSVL----Y---SG........
V2XZF1_MONRO/81-173.LI......KVTQ.................--------------..-EEA----...DYSIL----Y---PG........
F8PP65_SERL3/410-502.KI......VNNI.................--------------..-TDA----...DYVIL----F---TR........
K5W9L1_AGABU/439-532.TL......TFDI.................--------------..-GKA----...DYAVL----W---SQ........
K5VDP9_PHACS/379-470.KI......VANI.................--------------..-ADA----...DYAVL----F---TQ........
J4I894_FIBRA/337-429.KI......VPDI.................--------------..-PQA----...DVVIL----A---QH........
M2QYA3_CERS8/374-465.KI......IADI.................--------------..-DKA----...DYVVL----N---PN........
A7RVV1_NEMVE/15-100.IV......SSKITPGVDTILLQESSKDKP--------------L.-...----........----.---..........
B7QFB5_IXOSC/8-93.ML......VQPG.................--------------..-VNP----...RAIRL----V---PA........
E9HFT5_DAPPU/11-109.HL......GEEP.................--------------..-RGC----...HAIEL----V---FP........
E9HFT5_DAPPU/369-468.NF......GETP.................--------------..-HSC----...HSIEL----V---FP........
F1REC1_DANRE/34-120.NL......CRNQEPG..AILLIDPTDATN--------------VT-QNT----........----.---..........
W5K9C2_ASTMX/12-98.VV......CRTQEPN..AILLAEPGEVSA--------------AT-DGA----........----.---..........
G3NA35_GASAC/14-100.VL......CKVQQPG..AILLLEPEERGS--------------IS-EST----........----.---..........
I3KA69_ORENI/14-100.ML......CNVQQPG..AILLTDPEDRSV--------------IP-EST----........----.---..........
H2URR7_TAKRU/15-101.VL......CSVQQPG..SILLIDPAAGSS--------------IP-ENA----........----.---..........
H3DBF1_TETNG/17-103.VL......CSVQQPG..AILLMNPVEGAA--------------IP-AST----........----.---..........
M4ASB2_XIPMA/13-99.IL......CSVQVPG..AILLIDPEENSS--------------VL-ESD----........----.---..........
F6WSD5_XENTR/10-90.EM......CRMQQPG..ALLLSAPGSAQ.--------------..-...----........----.---..........
G5C0W9_HETGA/11-94.TV......CWVQEPG..AVLLAQPGEVLA--------------ET-...----........----.---..........
H3AZ34_LATCH/10-93.GL......CRVQESG..AVLLADTEESEG--------------GW-...----........----.---..........
TE2IP_CHICK/5-85.GL......CRVQEPG..AVHLVQPGEPA.--------------..-...----........----.---..........
W5N779_LEPOC/21-104.MM......CGVQEPG..AILLADPKELNG--------------KA-...----........----.---..........
B3RX95_TRIAD/6-86.QV......IVHPTDGVIRLAEPDTLT...--------------..-...----........----.---..........
H3H3N9_PHYRM/2-81.EV......SATP.................--------------..-AGA----...MQIVD----C---ER........
M4BMY6_HYAAE/1-80.IV......SSTP.................--------------..-AGA----...VQLVD----C---ES........
K3X8H7_PYTUL/34-113.VV...........................--------------..-EQR----FMPGAVEL----V---ES........
D2V2T9_NAEGR/8-105.TI......SNDL.................--------------..-DTN----...GITHI----I---SV........
K0KC61_WICCF/18-95.EV......INDP.................--------------..-GAG----...YYISK----H---HD........
K1VGF5_TRIAC/277-367.EL......APEW.................--------------..-DST----...FVIRS----T---NV........
I7MFY6_TETTS/273-374.VV...IDNNRDE.................--------------..-PEE----...YFHVV----I---TS........
D8M843_BLAHO/73-162.DV......EHFY.................--------------..-..S----RSRVGIII----A---KN........
D1ZZU6_TRICA/469-555.IV......AENP.................--------------..-SED----...VDYFI----T---SE........
F1N2F9_BOVIN/552-641.EL......EDYM.................--------------..-SER----...VQFVI----T---AQ........
H9G8R9_ANOCA/562-651.EV......EDYM.................--------------..-NER----...VNYVI----T---AQ........
G4VGJ3_SCHMA/541-631.TL......HQYM.................--------------..-SNE----...VQYVI----T---RS........
A0A068XE55_HYMMI/504-594.KV......ELNM.................--------------..-NTD----...VEFVV----S---RA........
H2ZBQ2_CIOSA/420-509.YL......QESI.................--------------..-NDN----...VKYAL----T---QS........
W5JUY9_ANODA/538-620.TM......TKAI.................--------------..-NDA----...KFIVT----R---NK........
F4PQL1_DICFS/4-97.TI......YYEF.................--------------..-RSD----...TITHV----I---AS........
K1PXK2_CRAGI/835-912.KV......TSSS.................--------------..-SKA----...DIYVG----S---DF........
Q5KDC9_CRYNJ/1333-1431.GI......LTSP.................--------------..-TLA----...GFLVL----P---LP........

PF16759

H2ZXR2_LATCH/884-956-DL-------------------------VP--------------EFDTSG.......ATHTV----S-------------
F6S783_MACMU/933-1005-DL-------------------------VQ--------------EFDMTS.......ATHVL----G-------------
D2W3T0_NAEGR/824-906-.I-------------------------VE--------------SSFSDD.......ITHII----T-------------
H3CY38_TETNG/809-881-EL-------------------------VP--------------EYDAAA.......ATHTM----A-------------
G3QCE5_GASAC/909-981-DV-------------------------VQ--------------DYEVAT.......ATHTL----A-------------
Q1RL58_CIOIN/781-858-DV-------------------------LG--------------NDQFKE.......ATHIV----Q-------------
E0VGK6_PEDHC/807-896-KL-------------------------YD--------------PEKETSVENGKNKVTHVI----H-------------
H0Z3J4_TAEGU/853-925-DL-------------------------VS--------------EGDTAS.......ATHVL----G-------------
H2MK50_ORYLA/283-355-DL-------------------------VA--------------DYDAAS.......ATHTL----A-------------
C3XPG8_BRAFL/848-925-DI-------------------------VQ--------------DYAMSQ.......ATHVV----E-------------
D6WBL1_TRICA/353-434-SV-------------------------LT--------------NDKPEE.......ATHVL----H-------------
F2US92_SALR5/1151-1238-EL-------------------------VN--------------.AMGGD.......VTHVV----V-------------
D6WBL2_TRICA/760-840-QI-------------------------CK--------------HGESEN.......ATHMI----H-------------
H2Z1K6_CIOSA/772-849-DV-------------------------LK--------------ENELKL.......ATHVV----Q-------------
A0A0D2X4A3_CAPO3/1228-1306-TI-------------------------VK--------------PAELDL.......CTHVV----V-------------
F6WXI9_XENTR/905-977-DL-------------------------VP--------------EYDLPT.......ATHVM----G-------------
J9JUI3_ACYPI/779-867-TP-------------------------LN--------------SSNELA.......PTHVI----V-------------

PF16770

Q0TZK5_PHANO/609-711-FI-------------------------TD..............DF-KK.-------VDLVCAPKPV-------------
C4R1B3_PICPG/699-801-KI-------------------------VD..............NP-SSK-------VNCIISPSIM-------------
G2QHK9_THIHA/602-704-QI-------------------------VP..............EN-AP.-------CNYLAAPGMV-------------
M3JFE1_CANMX/645-749-LI-------------------------LSE.FT..........NN-QT.-------VNTLIAPKIL-------------
E9CRG1_COCPS/597-699-MV-------------------------VQ..............DA-SK.-------CSHLAAPSIL-------------
M2M1A3_BAUCO/659-760-EV-------------------------TQ..............DP-SQ.-------VNILVAPSIK-------------
G4NCT3_MAGO7/597-703-NI-------------------------VQ..............EG-QP.-------CDYLAAPRVV-------------
F2SLK3_TRIRC/597-699-LV-------------------------IP..............DP-SR.-------CTHLAAPSIK-------------
R8BK69_TOGMI/621-723-QI-------------------------VQ..............DN-MP.-------CDYLAAPQVV-------------
S3D3M8_GLAL2/608-712-HV-------------------------IQ..............DA-RK.-------CSHLAAPNLV-------------
C7YM63_NECH7/596-698-QI-------------------------VQ..............EG-QP.-------CDYLAAPHIV-------------
C4JTM0_UNCRE/600-702-MV-------------------------VA..............DA-SR.-------CTHVAAPSIL-------------
C8V3U9_EMENI/593-695-MV-------------------------VQ..............DA-RK.-------CSHLAAPSVL-------------
Q6BZF3_DEBHA/634-743-KV-------------------------LSDY............ST-KQG-------INTLIAPRIL-------------
I1RVV5_GIBZE/601-703-QI-------------------------VG..............EG-QP.-------CDYLAAPNVV-------------
L8WY45_THACA/745-841-SF-------------------------TED.............DP-SQ.-------CTHLVVNSIS-------------
C5DS98_ZYGRC/912-1023-TI-------------------------HNE.......IT..SENV-GK.-------LDGIIAPKKL-------------
K5WLU5_PHACS/1099-1194-KF-------------------------TA..............KP-LE.-------CTHLVAHKIV-------------
Q75AR5_ASHGO/635-742-IL-------------------------QE..............EI-EED-------TNCIIGPKKA-------------
B6K613_SCHJY/586-680-QV-------------------------TE..............NP-AK.-------CTHLVTDKIV-------------
G0W9V9_NAUDC/944-1052-RI-------------------------YFT.......IN..SENM-NT.-------LNGIIAPKKS-------------
I2GZK5_TETBL/782-893-KI-------------------------HDD.......IT..SDNI-DK.-------LNTIFAPKKM-------------
N1JBZ0_BLUG1/603-705-LI-------------------------TL..............NT-WQ.-------CTHLAAPSMV-------------
E9EQX4_METRA/605-707-LI-------------------------VQ..............EG-QA.-------CDYLVAPQVV-------------
G3MZP9_BOVIN/976-1073-EV-------------------------AE..............SA-QK.-------CTHLIASKVT-------------
Q6CN34_KLULA/656-761-II-------------------------TP..............EI-ESF-------TNTIIAPKKA-------------
L2GJC4_COLGN/595-697-LI-------------------------VQ..............DD-KP.-------SDYLAAPHMV-------------
T5A5F6_OPHSC/606-708-QI-------------------------VN..............EG-QP.-------CDYVAAPKVV-------------
N1Q1B5_DOTSN/497-598-LL-------------------------TQ..............DP-AH.-------VDILVAPRIL-------------
L0PC51_PNEJ8/4-94-..-------------------------..................-...-------CTHLIASRIQ-------------
G3AMT0_SPAPN/577-678-EI-------------------------ISD.............LS-TQ.-------PNTLIAPKIL-------------
I2H240_TETBL/888-996-RI-------------------------YQS.............TK-TKS-------LDTIISPKFV-------------
C5M5V1_CANTT/627-732-KI-------------------------ITD.FN..........TK-YE.-------PNTLIAPRIL-------------
G8BF53_CANPC/627-730-KV-------------------------ITD.............LS-KYT-------PNTLIAPKIL-------------
A5DUV3_LODEL/733-836-KI-------------------------VSD.L...........TR-TK.-------PNTLIAPKIL-------------
H6BTR1_EXODN/609-711-IC-------------------------TL..............EP-AR.-------ATHLAAPRIV-------------
A7TEV9_VANPO/803-912-YI-------------------------YNE...........VDEM-YQ.-------LNTIIAPKKL-------------
D5G6X4_TUBMM/591-693-QC-------------------------VN..............DP-TT.-------CTHLAAPHIV-------------
J3P060_GAGT3/622-731-QI-------------------------VQ..............EG-QP.-------CDYLAAPKVV-------------
G1X016_ARTOA/638-741-QC-------------------------IE..............NP-DAH-------VTHVCAPRVV-------------
J7R641_KAZNA/728-836-KI-------------------------VKH...........ENEH-VRH-------LNCIVAPKVM-------------
A5DNV2_PICGU/524-631-KV-------------------------NKE.LT..........KA-HR.-------VEVIIAPRIL-------------
BRC1_SCHPO/650-744-SI-------------------------TS..............NP-SK.-------CTHLIAPRIL-------------
G0S8X0_CHATD/601-703-QI-------------------------VQ..............DT-VP.-------FTHLAAPSMI-------------
B6K1B2_SCHJY/418-515-MI-------------------------VD..............DY-LQ.-------CTHLIAPKIV-------------
R7YHQ6_CONA1/603-705-AL-------------------------TQ..............SP-TE.-------VTLLCAPRLI-------------
S6EZG3_ZYGB2/878-989-TI-------------------------HND.......IT..NENI-AK.-------LNTVIAPKKL-------------
C5DDJ9_LACTC/677-784-TI-------------------------LK..............AV-DVQ-------CNTIIAPKKM-------------
RT107_YEAST/820-925-KI-------------------------FDN...........IKET-DK.-------LNCIFAPKIL-------------
T1K2U0_TETUR/823-921-TL-------------------------IN..............EY-NK.-------CTHLIVNRIV-------------
M7T0V6_EUTLA/570-672-QV-------------------------VA..............DG-NP.-------CDYLVAPQLV-------------
S3BRI5_OPHP1/687-789-QI-------------------------VQ..............DS-QP.-------CDYLAAPCLV-------------
G3AYG3_CANTC/572-676-KI-------------------------SS..............GA-GK.-------INCLIAPRIL-------------
G8YB77_PICSO/622-730-RI-------------------------IQD.VT..........HA-SD.-------LDTIIAPKIL-------------
F0U567_AJEC8/604-706-HI-------------------------VQ..............DA-SK.-------CTHLAAPSVL-------------
S9VT84_SCHCR/649-743-TI-------------------------IS..............NP-SK.-------CTHLVAPRIL-------------
W1Q8C3_OGAPD/435-537-KV-------------------------VE..............QP-TNS-------LNCIIAPGIL-------------
G2YB22_BOTF4/618-722-SL-------------------------WT..............GY-GK.-------VNIMAAPKMV-------------
M7PGB1_PNEMU/569-665-AT-------------------------VQ..............DA-KD.-------CTHLVTSRIQ-------------
M1VXB8_CLAP2/609-711-QV-------------------------VQ..............TG-QP.-------CDFLVAPQIV-------------
N1QC64_PSEFD/642-743-EL-------------------------TT..............DP-KD.-------VDILVAPKLL-------------
Q5ALY1_CANAL/652-759-KI-------------------------VND.ID..........NN-TS.-------LNTLIAPKIL-------------
G2WSE1_VERDV/588-690-HI-------------------------VS..............EN-QP.-------CDYLAAPFMV-------------
G0VDU3_NAUCC/653-763-KI-------------------------LDE...........IEVG-NGH-------MNCIIAPKKM-------------
F9X0T3_ZYMTI/525-626-LL-------------------------TS..............DP-KN.-------VDILVAPKLL-------------
Q6FR08_CANGA/839-955-KL-------------------------QHDNVDQHIFEEQRGQRG-HNR-------INTIFAPKRL-------------
H2AVG7_KAZAF/692-804-KI-------------------------YGN.......ITPNESSL-YH.-------LNTIIAPRKL-------------
G8JP23_ERECY/643-750-VI-------------------------HQ..............DI-KQD-------SNCIIAPKKA-------------

PF12738

MCPH1_HUMAN/9-75-------------YQST-------------WDKAQKR-----------------------G.V--KLVSVLW--------
ECT2_MOUSE/179-242-------------QGEK-------------FRVAVSL-----------------------G.T--PIMKPEW--------
A2R3M9_ASPNC/121-184-------------EGEK-------------YKFATQW-----------------------G.I--RIVTVKW--------
A7F1C2_SCLS1/119-182-------------EGNK-------------YKAAKSW-----------------------G.L--RIVSAEW--------
A7S5M3_NEMVE/449-511-------------ESLK-------------YKKAREW-----------------------G.I--PCINAKW--------
A9RB53_PHYPA/468-530-------------AGEK-------------YENAERL-----------------------G.I--RCVTANW--------
B0DMV8_LACBS/502-564-------------TGLK-------------FDKAQEW-----------------------G.I--PVVSIGW--------
B2VU23_PYRTR/350-412-------------NSEK-------------CEAAVEW-----------------------G.V--NIVNHLW--------
B2W796_PYRTR/229-291-------------RGPS-------------WEKAVEN-----------------------N.I--PVVVPDW--------
B2W7P6_PYRTR/114-177-------------SGKK-------------YEHALNW-----------------------G.M--KIVALEW--------
B3RL44_TRIAD/702-764-------------SGEK-------------FFKAKEW-----------------------R.I--FTVNCKW--------
B4H593_DROPE/186-250-------------LLST-------------YKKAVEW-----------------------K.I--PVVSVLW--------
B4KSD3_DROMO/76-140-------------LLST-------------YKRAQSW-----------------------N.I--PIVSILW--------
B6HL54_PENCW/128-191-------------DGEK-------------YKFATQW-----------------------N.I--KVVSVKW--------
B6Q6C3_PENMQ/111-174-------------SGAK-------------YKFATQW-----------------------S.I--KVVSAKW--------
C0NFA4_AJECG/121-184-------------YGQK-------------YKYATLW-----------------------K.I--TVVSLKW--------
C1FFW2_MICSR/561-624-------------EGKK-------------YEAAVGW-----------------------G.L--HAVTVEW--------
C4M4C9_ENTHI/17-80-------------TSDK-------------ARHAKRW-----------------------G.V--PVLNHQW--------
C5FMN4_ARTOC/111-174-------------EGKK-------------YKFAILW-----------------------G.V--KVVSLKW--------
RAD4_SCHPO/105-167-------------SGRK-------------YEYALKW-----------------------K.I--NVVCVEW--------
Q16W28_AEDAE/219-283-------------LLST-------------YQKAKKM-----------------------N.V--PVVSILW--------
Q1K5Z2_NEUCR/339-401-------------NGEK-------------CEAAKEW-----------------------N.I--EIINHLW--------
Q2H787_CHAGB/324-387-------------EGRK-------------YHAAKNW-----------------------G.V--TTVSVEW--------
Q4CP92_TRYCC/1-63-------------EGGK-------------CRVARER-----------------------G.I--PCVTPAW--------
A0A0D1CFS9_USTMA/599-667-------------EGKH-------------AQHARSC-----------------------G.V--PVVGLDF--------
Q5TRD6_ANOGA/110-173-------------GGEK-------------YRYAMTF-----------------------R.L--AIIRPNW--------
Q6CN34_KLULA/351-414-------------SGKK-------------FEAARAW-----------------------ACC--TAANHLW--------
PAXI1_MOUSE/102-165-------------KGEK-------------YERAVKR-----------------------TSI--KIVTPDW--------
Q6Z553_ORYSJ/10-72-------------EGKK-------------YDIARRL-----------------------R.T--RVVSHRW--------
Q9U7D8_DROME/117-180-------------GGEK-------------YQYAKTF-----------------------R.L--TVVRPAW--------
B9GSH3_POPTR/111-175-------------EGEK-------------YELANKM-----------------------KKM--KLVNHRW--------
D7SMI0_VITVI/4-66-------------EGRK-------------YSLAKKF-----------------------K.T--LIVNHRW--------
F4I701_ARATH/188-251-------------EGDK-------------YKVARKW-----------------------GHI--QIVTRKW--------
F4I701_ARATH/667-729-------------KGDK-------------YVRASKW-----------------------G.I--ISVTPDW--------
F6XFW7_XENTR/204-267-------------KGQK-------------YECARKW-----------------------N.V--HCVSVQW--------
H0ZRM8_TAEGU/5-67-------------RLST-------------WKKAQKM-----------------------G.V--KLVSVLW--------
H3C8W0_TETNG/80-141-------------VGLK-------------YEKAKEW-----------------------K.I--PCVNAQW--------
I1QYC0_ORYGL/209-271-------------GGDK-------------YVVAQKW-----------------------GNI--HIVVPKW--------
I1QYC0_ORYGL/675-736-------------SGPK-------------YEAYYSR-----------------------G.I--PTITAEW--------
Q4WQC2_ASPFU/345-407-------------HSEK-------------CAAAKEW-----------------------G.L--HVVNHLW--------
Q7JUM5_DROME/187-251-------------LLST-------------YKKATEW-----------------------N.I--PVVSILW--------
U5GIH0_POPTR/4-66-------------EGRK-------------YELASKF-----------------------D.T--LVVNHRW--------

PF00533

Y4211_ARATH/1089-1168............RRTEK.............FFAAAAS-----------------------G-S--WILKTDYVADS--K-
MDB1_SCHPO/384-455..........PLRRTHK.............FLLATSL-----------------------G-I--PLVSSQYLTDC--I-
MDB1_SCHPO/485-573.........DQEGRNMS.............ATGLNVY-----------------------K-I--ELVALSILRDR--I-
ECT2_MOUSE/266-341.............TVKD.............LPFEPSK-----------------------K-L--FVVKQEWFWGS--I-
PAXI1_HUMAN/701-776.............TGLK.............YEKAKEW-----------------------R-I--PCVNAQWLGDI--L-
PAXI1_HUMAN/860-934............TRTVK.............FLTAISV-----------------------V-K--HIVTPEWLEEC--F-
TDT_HUMAN/27-111........SDVLEWLQA.............QKVQVSS-----------------------Q-P--ELLDVSWLIEC--I-
RAD9_YEAST/994-1109R..FACLITKRHLRSLK.............YLETLAL-----------------------G-W--PTLHWKFISAC--I-
XRCC1_HUMAN/538-616...........WDPSFE.............EALMDNP-----------------------S-L--AFVRPRWIYSC--N-
Q93161_CAEEL/981-1063........GALETDSLD.............LLLWVFN-----------------------G-A--IIVKEQWMVDC--L-
PARP4_HUMAN/1-81..........DVLSQYQ.............LNSIQKN-----------------------H-V--HIANPDFIWKS--I-
TOPB1_HUMAN/101-176.............GSKK.............YLVAANL-----------------------K-K--PILLPSWIKTL--W-
TOPB1_HUMAN/195-271.............KGQK.............YECAKRW-----------------------N-V--HCVTTQWFFDS--I-
TOPB1_HUMAN/354-431...........DDELKQ.............FWNKSAH-----------------------R-P--HVVGAKWLLEC--F-
TOPB1_HUMAN/548-620................L.............GCEVEAT-----------------------V-G--EVVTNTWLVTC--I-
TOPB1_HUMAN/641-725.............GGSK.............YEAAKKW-----------------------N-L--PAVTIAWLLET--A-
TOPB1_HUMAN/900-978...........NDTNRE.............YKSVKER-----------------------G-V--HIVSEHWLLDC--A-
TOPB1_HUMAN/1260-1338............LRNEK.............YLASVAA-----------------------G-K--WVLHRSYLEAC--R-
Q20129_CAEEL/451-529..........QQERITI.............RKHLHQE-----------------------D-I--AIVTVGWVVEC--V-
Q20129_CAEEL/587-659..............................PMHELIS-----------------------F-D--AVVTDFYIYAS--I-
Q20129_CAEEL/679-749...............................DNPPRY-----------------------H-S--RTLDFSWIIAS--V-
DNLJ_HAEIN/592-668............AG.SK.............LAKAQEL-----------------------N-I--TVLTEEEFLAQ--I-
DNLI4_CANAL/673-756...........ERELPV.............SSQYLSK-----------------------G-I--DLVKPIWIYEC--I-
Q20129_CAEEL/128-204............EQTEK.............YKAAVNN-----------------------S-I--KLMRIGWIDDL--W-
O76369_CAEEL/929-1023........GILETESLE.............IFFWIFN-----------------------G-T--IIVKEQWMSDC--L-
PAXI1_MOUSE/588-668.............VSSM.............YTQALRE-----------------------R-K--RCVTAHWLNTV--L-
PARP1_MOUSE/385-463..........VEKMNKK.............MEEVKEA-----------------------N-I--RVVSEDFLQDV--S-
DNLI4_HUMAN/654-730.............NIRV.............KNIILSN-----------------------K-H--DVVKPAWLLEC--F-
DNLI4_HUMAN/814-898.........SRVADFKA.............FRRTFKR-----------------------K-F--KILKESWVTDS--I-
O16568_CAEEL/1044-1144EQRSCIILKHSDSKIEK.............KWQSMHA-----------------------M-Y--TLVDFSFLAEC--I-
TDT_MONDO/27-111........SDVLAWLKT.............HKMEKTT-----------------------Q-F--ELLDISWLIEC--M-
O16229_CAEEL/378-460........GVLETDDLS.............LLVWIFN-----------------------G-A--IIVKEKWMTDC--L-
DNLJ_HELPY/577-652............PG.SK.............LALAQKH-----------------------G-V--SVLNEEELLKR--L-
DNLJ_BACSU/590-666............AG.SK.............LTKAQEL-----------------------N-I--EVWNEEQLMGE--L-
DNLJ_MYCLE/607-683............PG.YK.............YDKAVEL-----------------------G-V--PILNEDGFRLL--L-
O44844_CAEEL/154-256D..SSVVLYFNDSVLHE.............KWTFANN-----------------------C-I--SFLGMGWLVEC--I-
DNLJ_BORBU/583-659............AG.SK.............LKKALSL-----------------------N-I--KIMSFEDIKSY--L-
BRCA1_RAT/1588-1669.........FVCERTLK.............YFLGIAG-----------------------G-K--WIVSYSWVIKS--I-
BRCA1_RAT/1701-1787.........AWTEDNDC.............PDIGQLC-----------------------K-G--RLVMWDWVLDS--I-
RFC1_SCHPO/236-313............AGPRK.............VETIKQH-----------------------K-I--PAINEDGLFYL--I-
DNLJ_AQUAE/619-696............PGATK.............LSKAKKY-----------------------G-V--KTITEEEFVNM--I-
CHS5_CANAL/164-246........TRENKQNPE.............YVKANDM-----------------------N-I--PIIRPEWLKAC--E-
DNLJ_TREPA/562-642............RTAQK.............LKKEQGV-----------------------A-L--EIISEDEFCRL--L-
DNLJ_CHLTR/581-657............AG.GK.............LKKAQDL-----------------------G-L--SIWNESELLRI--L-
O96271_PLAF7/208-298............LEDGRLFNEGRKYTKAFELQQQNKS-----------------------N-I--KILNEEELLKL--L-
PESC_LEIMA/317-390..........LP..................PGMKKHD-----------------------Q-L--EYVQPQYIFDC--L-
DNLJ_ECOLI/593-669............AG.SK.............LAKAQEL-----------------------G-I--EVIDEAEMLRL--L-
PARP1_CHICK/382-460..........VEKMSKK.............MEEVKDA-----------------------K-V--RVVSEEFLKDV--K-
DNLJ_THET8/589-664............PG.SK.............LEKARAL-----------------------G-V--PTLTEEELYRL--L-
DNLJ_ZYMMO/645-721............AG.SK.............LSKAKEL-----------------------D-I--SIIDEDRWHRI--V-
RAD4_SCHPO/2-79...........DTPKYK.............FAAKSRP-----------------------D-I--KIMSSEWIPVL--Y-
RAD4_SCHPO/392-473.........FSMKTRFK.............IQHATEW-----------------------N-V--RVVGVAWLWNI--I-
RFC1_DROME/232-309............AGPKK.............LAVAEEL-----------------------N-I--PILSEDGLFDL--I-
TDT_CHICK/27-111........PEVLDWLKG.............QAVGDSS-----------------------R-F--EILDISWLTAC--M-
BRCA1_HUMAN/1642-1723.........FVCERTLK.............YFLGIAG-----------------------G-K--WVVSYFWVTQS--I-
BRCA1_HUMAN/1756-1842.........AWTEDNGF.............HAIGQMC-----------------------E-A--PVVTREWVLDS--V-
RFC1_YEAST/153-230............AGPKK.............LEKIKQL-----------------------K-I--KAIDEEGFKQL--I-
RT107_YEAST/2-103PQTVHFVISNTINFPFY.............KIVYFDL-----------------------L-I--PVVSHTWVQDS--V-
RT107_YEAST/117-213V.SKLTFGSFSSSSTNK.............HTEKPLR-----------------------E-W--KFVYPIWILYH--F-
RT107_YEAST/261-352PDIDCYIGHSANSPILE.............KTKSIKP-----------------------E-I--HVGNVSWLFYM--F-
RT107_YEAST/370-453...........FKVAKK.............WSLDPQN-----------------------A-I--IVTNHMWLEQC--Y-
YPT4_CAEEL/930-1012........GILETDDLN.............LLIWIFH-----------------------G-S--IIVRDTWMVDC--L-
YPT4_CAEEL/1049-1141NLGPIFLLHDGTGDLDL.............YRSDPDK-----------------------M-F--TLFTEQQFMDL--L-
DPB11_YEAST/111-207.............LGAR.............VNAAIEQ-----------------------N-I--PIVHFKWILDC--Q-
DNLJ_SYNY3/591-667............PG.SK.............AAKAESL-----------------------G-I--KLLSEAEFLQL--L-
RHP9_SCHPO/535-640...........FSRKVK.............YLEALAF-----------------------N-I--PCVHPQFIKQC--L-
FCP1_YEAST/499-580...........STYKAR.............LAKKFNP-----------------------Q-I--KIVHPDWIFEC--L-
DNLI4_YEAST/681-767..........SCKTTTE.............CKALIDR-----------------------G-Y--DILHPNWVLDC--I-
DNLI4_YEAST/836-928RKDCMNEVHEKIKEQIK.............ASDTIPK-----------------------I-A--RVVAPEWVDHS--I-
Q09615_CAEEL/251-326.............IATA.............KINRIRE-----------------------N-E--IFIKADWITES--I-
BRC1_SCHPO/14-91.............SSPN.............VQEGSKR-----------------------S-L--RLAKTNWIRDC--V-
BRC1_SCHPO/105-183..........MGAKCKK.............VLDKPSL-----------------------S-I--KLIHPQWLLDC--L-
BRC1_SCHPO/216-293..........LKRDTIE.............FNLASNK-----------------------N-T--TIGTISWLLNL--F-
BRC1_SCHPO/311-386.............YGQK.............YGAAKVW-----------------------N-I--PTVHHSWLYSS--F-
CHS5_YEAST/166-249.......DLDNEESNEE.............LIRAKHN-----------------------N-I--PIVRPEWVRAC--E-
XRCC1_MOUSE/315-390.............NTPK.............YSQVLGL-----------------------G-G--RIVRKEWVLDC--H-
Q94046_CAEEL/514-600.............RNTN.............VMTSLEH-----------------------R-K--RIVSIQWIIDV--M-
Q94046_CAEEL/620-694..............ADK.............VTRAQEW-----------------------K-V--PVVNFQWIADA--Y-
DNLJ1_STRCO/643-719............PG.SK.............YDKAMQL-----------------------K-V--PVLNEDGFAVL--L-
DNLJ_RICPR/610-686............GG.SK.............LKKAKEL-----------------------N-I--KIIDEVEWLAF--I-
PARP1_ARATH/394-471..........TDIRDAE.............MRKARRM-----------------------K-V--AIVREDYLVDC--F-
D0MI04_RHOM4/636-709.............PGSK.............YDRARQL-----------------------G-I--PMLDEDGLLRL--L-
H9KXM3_CALJA/403-478............SGQSK.............SDKAAAL-----------------------G-T--KIIDEDGLLNL--I-
Q5AZH7_EMENI/325-400............AGPSK.............LATISKH-----------------------K-L--KTISEEGLFEL--I-

PF16589

K3WDG2_PYTUL/626-709..............SLF-------------RRAQRT........................G-I--RVVTAKWVFDS--I.
A2GB92_TRIVA/56-149...ICHSKRNQLDKAIE-------------KR............................K-V--VVVRPDFIFDC--V.
E4V0Q5_ARTGP/707-798.................-------------......SKNTYCIADRRTV..KVASLQKSAL-E--NVIRPSWIFDC--I.
H6BN77_EXODN/749-843.................-------------......VPDTICVATRRTV..KVASLQKQNN-K--EIVRPLWIFDC--I.
D7MMS2_ARALL/654-741................S-------------S.GIKYQAAKR...................Q-R--DVIHFSWVLDC--C.
D7SQI2_VITVI/653-740................S-------------K.GIKYQAAKL...................R-G--DIIHCSWVFDC--C.
M0S2G9_MUSAM/640-728................K-------------KAGIKYQAAVH...................H-G--DVIHYSWVLDC--C.
K7LC24_SOYBN/506-593................S-------------K.GFKFEAAKH...................H-G--DIIHYSWVLDC--Y.
Q5KPS9_CRYNJ/138-224FK...............-------------..............................R-H--KVVKEGWVVES--C.
A8WS89_CAEBR/455-544................S-------------QQDRASLRKIVQQE................D-I--NIVTVQWVIEC--V.
H2ANJ1_KAZAF/685-782.................-------------......KSNLRILCGKYTA..ECNVLIKR.G-Y--DILSPQWVIDC--V.
I1BS31_RHIO9/47-133.................-------------..............................K-Y--NILSHQYFLDC--I.
I2H6P9_TETBL/707-804.................-------------......ISKLRILSSKSTI..ECTDLVRR.G-Y--DVINLSWLFDC--L.
D2V2T9_NAEGR/209-297................N-------------EPYTLKN.......................V-E--NITTAQWIDDS--L.
D8M2G5_BLAHO/342-422................V-------------DSDIYK........................D-D--RAVSAKWLRSC--T.
G8BNV8_TETPH/119-211................T-------------DDPAITAVTNFNRNL...............D-I--GFVFVTWILLC--F.
M2N998_BAUCO/197-300GGGLAGSKIQKEITSKR-------------GA............................V-V--KYVTVEWVMES--V.
M2ZQ43_PSEFD/117-220GGGLAASKIHKEITQMR-------------GK............................S-A--KFITADWVTES--I.
V4Z6W2_TOXGO/178-272................V-------------AMGNQRWRHLREQGGEGK............K-Y--VVVTVKWVFDC--I.
A3LW54_PICST/41-121.................-------------..............................G-R--RSYRVQYIDDC--V.
G3AM46_SPAPN/45-124................E-------------..............................E-G--HGIQLRFIDEC--I.
M3K224_CANMX/72-151................K-------------..............................M-L--GYFKLKFIDDC--I.
Q59XT2_CANAL/89-168................D-------------..............................L-Y--GFSKLKFIDDC--I.
A5DYD1_LODEL/66-146..............KD.-------------..............................M-G--GYVRTQFIDDC--I.
G8BJX2_CANPC/111-190..............HL.-------------..............................G-G--.FVRIDYIDDC--V.
C4R0P7_PICPG/22-117................Q-------------EILNRNLQTVPN..................N-R--QVYRLSFIDDC--I.
C4VBY8_NOSCE/44-123..............NKV-------------NINTYELY......................K-S--VVLDEVYIFEC--IY
R4XAV8_TAPDE/3-87.................-------------..............................D-A--SWLNFRYIDDA--L.
A7EAG9_SCLS1/12-89.................-------------...............................-.--GSVSWKFIEES--A.
G2YA12_BOTF4/12-89.................-------------...............................-.--GSISWKFIEDS--A.
E3QRM6_COLGM/14-92.................-------------...............................-.--TSLHWKFIKDS--I.
H1V395_COLHI/14-91.................-------------...............................-.--GSLHWKFIKDS--V.
L2G6F7_COLGN/14-91.................-------------...............................-.--DSLSWNFIKDS--V.
E3S9F7_PYRTT/19-96.................-------------...............................-.--GSISYEFIQRS--V.
G2QX03_THITE/15-91.................-------------...............................-.--GSVSWKYVEDS--V.
E9CWR8_COCPS/8-85.................-------------...............................-.--GSYSFKFIDRC--L.
N1JJ21_BLUG1/13-90................G-------------KFA...........................P-P--RSVSWTYIRDS--D.
M5BM65_THACB/48-146..............TEE-------------GELELATRSTR...................T-R--QVVSFLFIEES--I.
A7TGW3_VANPO/860-963..............HTE-------------NRKEVMKKIRRALVCLDPNSMQVPV.....L-P--RIVDANWIDAC--I.
E3LW19_CAERE/691-776................G-------------PIDEPQH.......................R-A--RTADYSWIIAS--V.
A7TIC7_VANPO/66-154...N..DT.........-------------..............................K-L--RTVTSTFIKAC--C.
G8C1X2_TETPH/45-136...N..ST.........-------------..............................N-L--NTVTATYIKAC--C.
E7Q896_YEASB/122-207.................-------------..............................N-L--PTVTPTYIKAC--C.
H2APC0_KAZAF/72-157.................-------------..............................N-L--PTVTPTYIKAC--V.
G0VI01_NAUCC/119-206...N..DT.........-------------..............................K-L--PTVTPTYIKAC--V.
C5DTR6_ZYGRC/67-154...NDT...........-------------..............................R-L--PTVNPTYIRAC--C.
J7S744_KAZNA/61-148...N..YT.........-------------..............................N-R--ITVTPTYLKAC--A.
F2Z6A0_CANGA/80-168...N..NT.........-------------..............................E-L--KTVTSTFIRAC--V.
I2GXL7_TETBL/69-154...N..NT.........-------------..............................G-I--STLSPTYIKEC--I.
G0WD26_NAUDC/165-250...N..DT.........-------------..............................K-L--PTITTTYIRTC--I.
G8ZLB0_TORDC/16-100...N..DT.........-------------..............................R-L--PTVTPAYIKAC--C.
C5DD36_LACTC/53-131...NAS...........-------------..............................D-L--PTVTPTYIKTC--C.
D3BEV4_POLPA/10-104................E-------------EVEKASYKIKGATKLCDEG...........E-L--RLVSTQYITDC--V.
F0Z8S8_DICPU/18-113................E-------------ELEKNMNSTKIQSAIKIP............T-I--EILSIEFISHC--I.
R0KT87_NOSB1/49-128..............FNK-------------DKEEGDGA......................Y-I--PVIHIRFIYDS--I.
A8N1C0_COPC7/345-440................A-------------PHKMKDYERFLKAAQAH.............N-V--PAVRGHFVEHC--D.
B0CPN9_LACBS/390-485................S-------------.QKQKTFLDLLRSTIDA.............G-R--PAVSANFIRDC--V.
V2XZF1_MONRO/81-173................S-------------....KTFRASLKEAAAT.............N-A--IAVNTSFINDC--V.
F8PP65_SERL3/410-502................S-------------....KTFPGLAKEAQNV.............N-K--RPLQSSFVVDC--V.
K5W9L1_AGABU/439-532................S-------------....TTFKEILISASLE.............R-T--PAVTYSFILDT--V.
K5VDP9_PHACS/379-470.................-------------...ALGSWDYLRTAVEA.............G-T--PAVKALYITDC--L.
J4I894_FIBRA/337-429................T-------------....KPFSDWLRRAQQA.............K-R--PTAQASYVHDC--I.
M2QYA3_CERS8/374-465................S-------------....HSFRQLLERAENF.............Q-K--HAVNAQFVFDC--A.
A7RVV1_NEMVE/15-100.................-------------..............................L-D--GYTSSEYIKDC--I.
B7QFB5_IXOSC/8-93................G-------------ATVSVND.......................R-D--PVFSTEFVREC--S.
E9HFT5_DAPPU/11-109................E-------------DITDIDGI......................D-S--DLFKAEYIEEC--K.
E9HFT5_DAPPU/369-468................E-------------VIEGIDEI......................D-S--DVFKAEYVEEC--I.
F1REC1_DANRE/34-120.................-------------..............................G-Q--KYISTKYILDC--V.
W5K9C2_ASTMX/12-98.................-------------..............................G-Q--FYISTQYIRDC--V.
G3NA35_GASAC/14-100.................-------------..............................T-H--WFVSTQYIFDC--I.
I3KA69_ORENI/14-100.................-------------..............................A-H--WYVSTQYIYDC--V.
H2URR7_TAKRU/15-101.................-------------..............................T-H--WYVSTQYILDC--I.
H3DBF1_TETNG/17-103.................-------------..............................T-H--WYVSTRFIQDC--V.
M4ASB2_XIPMA/13-99.................-------------..............................A-H--RYVSTQYIHDC--I.
F6WSD5_XENTR/10-90.................-------------..............................G-A--QYVSTAYIMDC--V.
G5C0W9_HETGA/11-94.................-------------..............................S-G--DFISTRYILDC--V.
H3AZ34_LATCH/10-93.................-------------..............................S-P--EHISVRYITDC--V.
TE2IP_CHICK/5-85.................-------------..............................P-D--GAVSTDYVVAC--V.
W5N779_LEPOC/21-104.................-------------..............................A-A--GYVSTHYILDC--V.
B3RX95_TRIAD/6-86.................-------------..............................P-L--GYVSASFIFDS--V.
H3H3N9_PHYRM/2-81................L-------------DAR...........................H-P--EWISTEFIKDS--V.
M4BMY6_HYAAE/1-80................M-------------DAR...........................H-P--ERISTDFVKDS--I.
K3X8H7_PYTUL/34-113..............DRL-------------KI............................G-T--KWVSVDFVYDS--V.
D2V2T9_NAEGR/8-105................E-------------METNSENENIDTLNSSQVKNP.........D-R--FIISPQFVYTS--I.
K0KC61_WICCF/18-95..............P..-------------..............................L-R--DAVDPKFIYES--T.
K1VGF5_TRIAC/277-367................L-------------SRSKSAVKGNVTS.................C-P--LAVSVKWVKES--L.
I7MFY6_TETTS/273-374................G-------------AQNIDKNSLKSLKSSSND............G-Q--IIVSHKWLLDS--I.
D8M843_BLAHO/73-162...VCYSKEQQYLKKP.-------------..............................S-L--RVLDPQWILDS--I.
D1ZZU6_TRICA/469-555.................-------------..NNAENLKSYNS.................R-A--ECLRPDWLWDC--H.
F1N2F9_BOVIN/552-641................E-------------WDPSFEEALTDNP.................S-L--VFVRPRWIYSC--N.
H9G8R9_ANOCA/562-651................E-------------WDDTFEEALNENA.................N-L--SFVRPRWIYNC--N.
G4VGJ3_SCHMA/541-631................A-------------WDVEFDNALSSNT.................D-L--IFIRPEWIFAC--D.
A0A068XE55_HYMMI/504-594................A-------------WCSDFDEALEVCP.................S-L--IFVKPEWIYAC--D.
H2ZBQ2_CIOSA/420-509................S-------------WNKELQNALDHNR.................S-V--TFVRPEWVFKC--G.
W5JUY9_ANODA/538-620................L-------------IVESSC........................K-A--RLVKPLWIFEC--H.
F4PQL1_DICFS/4-97................N-------------DTDLVNDIPKEILKLNTLQ...........K-I--VIIRKKWLMDC--L.
K1PXK2_CRAGI/835-912..............LP.-------------..............................E-K--TSVNPLWILDC--V.
Q5KDC9_CRYNJ/1333-1431................P-------------SSPINNPDHIEAVRSVRGQE..........W-R--VVVSEEWVLDC--V.

PF16759

H2ZXR2_LATCH/884-956-------------D.L.................EGNS-----------------------N-A--KRVSPNWIWEC--V-
F6S783_MACMU/933-1005-------------S.R.................DKNP-----------------------A-A--QQVSPEWIWAC--I-
D2W3T0_NAEGR/824-906-------------SSSRIT.......PEIAKLVSENP-----------------------Q-V--NVVSSEWIWHS--I-
H3CY38_TETNG/809-881-------------E.P.................EDDS-----------------------G-A--QRVTPSWIWEC--I-
G3QCE5_GASAC/909-981-------------E.P.................EDDS-----------------------Q-A--ERVSPDWIWEC--I-
Q1RL58_CIOIN/781-858-------------C.D............SVKVADIPI-----------------------S-A--SLVTASHVWEC--I-
E0VGK6_PEDHC/807-896-------------LNKVG........KIVKNEKYWDK-----------------------G-V--RHVHVNWIWNS--I-
H0Z3J4_TAEGU/853-925-------------D.I.................AGSP-----------------------G-A--QRVTARWIWEC--I-
H2MK50_ORYLA/283-355-------------P.P.................GEDS-----------------------R-A--QRVSPSWIWEC--I-
C3XPG8_BRAFL/848-925-------------D.P............EQKNMNGKT-----------------------D-A--QLVTVDWLWQC--I-
D6WBL1_TRICA/353-434-------------LKDT..........ISQPTIHCAN-----------------------S-A--KHVIVEWIKDT--V-
F2US92_SALR5/1151-1238-------------PDLDVDKW..DAATKSAVSMASST-----------------------G-A--RVVTAKWLWDS--I-
D6WBL2_TRICA/760-840-------------LNSM...........VPEIDQCNP-----------------------D-V--KHVTVDWIKNC--V-
H2Z1K6_CIOSA/772-849-------------S.D............SVKRLDISS-----------------------E-A--LSVTSKYVWEC--I-
A0A0D2X4A3_CAPO3/1228-1306-------------PSLD...........SAASDRDNG-----------------------N-A--PAVLPSWIDAC--I-
F6WXI9_XENTR/905-977-------------REP.................ECIA-----------------------D-A--KHVTPHWIWEC--I-
J9JUI3_ACYPI/779-867-------------QKKEHNRSSEKPMKEEKKEKKKSL-----------------------N-A--TAVCAQWFWDS--I-

PF16770

Q0TZK5_PHANO/609-711-------------RTKK-------------FVAALAC-----------------------A-P..TLVSTTYLDAA..LK
C4R1B3_PICPG/699-801-------------RTEK-------------FLITLSK-----------------------S-P.NLLLHESFLLSV..LQ
G2QHK9_THIHA/602-704-------------RTMK-------------FLRCLAK-----------------------G-P..DVINSSFITAC..IE
M3JFE1_CANMX/645-749-------------RTAK-------------FLRCLST-----------------------V-D..NIIHPQYLVDI..LK
E9CRG1_COCPS/597-699-------------KTQK-------------FVNALAY-----------------------A-P..KIINCDFITDC..VK
M2M1A3_BAUCO/659-760-------------TTRK-------------FVAAIAN-----------------------G-P..IVVDPTYLDVA..LN
G4NCT3_MAGO7/597-703-------------RTQK-------------FLTTLAR-----------------------G-P..ELISDQFLVDA..LE
F2SLK3_TRIRC/597-699-------------RTQK-------------FLNALAH-----------------------A-P..VIINSNFITDC..LE
R8BK69_TOGMI/621-723-------------RTIK-------------FLRCLAK-----------------------G-P..EVINSTFVEDC..LS
S3D3M8_GLAL2/608-712-------------RTKK-------------FLCALAM-----------------------G-P..TIISTDFIEACSSVK
C7YM63_NECH7/596-698-------------RTVK-------------FLCALAR-----------------------G-P..TVISSTFIDKT..LE
C4JTM0_UNCRE/600-702-------------KTPK-------------FVNALAF-----------------------G-R..KVISCDFITDC..IA
C8V3U9_EMENI/593-695-------------RTPK-------------FVNAIAY-----------------------S-P..VIVQVEFITQC..LK
Q6BZF3_DEBHA/634-743-------------RTAK-------------FLRSLSQ-----------------------V-D..KIIHPNYLIDV..LK
I1RVV5_GIBZE/601-703-------------RTVK-------------FLCALSR-----------------------G-P..SVISSDFIEQA..LD
L8WY45_THACA/745-841-------------RTEK-------------FLCAFPV-----------------------C-K..YIVTMRWLQDS..IK
C5DS98_ZYGRC/912-1023-------------RTAK-------------FLKSLSF-----------------------H-PLRYALTPKFLKDI..LR
K5WLU5_PHACS/1099-1194-------------RTEK-------------FLCAMAV-----------------------A-P..HIVTEKWVAAC..VS
Q75AR5_ASHGO/635-742-------------RTAK-------------FLTSFSF-----------------------H-PLKYALLPKFITEI..LS
B6K613_SCHJY/586-680-------------RTEK-------------FLCSLPY-----------------------A-P..FVVTSAWVVQS..IL
G0W9V9_NAUDC/944-1052-------------RTIK-------------FLKSYSF-----------------------Q-PLRYLLLPNFIYDV..LK
I2GZK5_TETBL/782-893-------------RTAK-------------FLKSFSF-----------------------K-PLKYLLTPSFLIDL..LA
N1JBZ0_BLUG1/603-705-------------RTKK-------------FLCALAS-----------------------A-P..IIVSTEFVDAC..LR
E9EQX4_METRA/605-707-------------RTVK-------------FLCALAR-----------------------G-A..VVLSSDFIDKV..LE
G3MZP9_BOVIN/976-1073-------------RTVK-------------FLTAISV-----------------------V-K..HIVTPEWLEEC..FK
Q6CN34_KLULA/656-761-------------RTAK-------------FLKSFSF-----------------------K-PLKYALTPMFITNI..LT
L2GJC4_COLGN/595-697-------------RTVK-------------FLKTLAK-----------------------G-P..TILSSKFIDEA..LD
T5A5F6_OPHSC/606-708-------------RTVK-------------FLCALAR-----------------------G-A..TALTTDFVEAV..LE
N1Q1B5_DOTSN/497-598-------------RTKK-------------FVSALVC-----------------------A-P..LVVDTSFLEYA..LS
L0PC51_PNEJ8/4-94-------------RTQK-------------FLSALAY-----------------------A-P..KILSVDWIRMC..IK
G3AMT0_SPAPN/577-678-------------RTEK-------------FLRSLAK-----------------------V-D..HIVHPKYLIDV..LK
I2H240_TETBL/888-996-------------RTAK-------------FLTSLSF-----------------------H-PLKHAINPEFIKDI..LN
C5M5V1_CANTT/627-732-------------RTEK-------------FLRSLSK-----------------------V-D..RIIHPNYLINI..LE
G8BF53_CANPC/627-730-------------RTEK-------------FLRSLSK-----------------------V-D..RIVHPSFIIDV..LA
A5DUV3_LODEL/733-836-------------RTEK-------------FLRSLST-----------------------V-D..KIIHPSFIVDV..LA
H6BTR1_EXODN/609-711-------------RTQK-------------FVTALAY-----------------------A-P..MVITTDFIEAC..LK
A7TEV9_VANPO/803-912-------------RTVK-------------FLKSLSF-----------------------T-PLQNALLPDFVMAI..LD
D5G6X4_TUBMM/591-693-------------RTEK-------------FCCALAK-----------------------A-P..IIVSTEWPKAC..LK
J3P060_GAGT3/622-731-------------RTQK-------------FLTTLAR-----------------------G-P..DLINVDFLTQA..LE
G1X016_ARTOA/638-741-------------RTEK-------------FVCALAR-----------------------A-P..IIVNSNWVDEC..LK
J7R641_KAZNA/728-836-------------RTAK-------------FLISLSF-----------------------K-PLKYVLLPQFISDV..LN
A5DNV2_PICGU/524-631-------------RTEK-------------FLTSLSQ-----------------------A-D..KIIHPQYLIDL..LK
BRC1_SCHPO/650-744-------------RTSK-------------FLCSIPY-----------------------G-P..CVVTMDWINSC..LK
G0S8X0_CHATD/601-703-------------RTQK-------------FLVALAK-----------------------G-P..DVISSDFVTAC..IE
B6K1B2_SCHJY/418-515-------------KTKK-------------FLCALPY-----------------------A-K..YILQLSWLFAC..VD
R7YHQ6_CONA1/603-705-------------RTRK-------------FVAALAA-----------------------A-P..TVVSSGFLDSC..LR
S6EZG3_ZYGB2/878-989-------------RTAK-------------FLKSLSF-----------------------H-PLKYALTPTFLKDI..LR
C5DDJ9_LACTC/677-784-------------RTAK-------------FLTSFGF-----------------------H-PLKWALMPEFVSEL..LS
RT107_YEAST/820-925-------------RTEK-------------FLKSLSF-----------------------E-PLKFALKPEFIIDL..LK
T1K2U0_TETUR/823-921-------------RTSK-------------FMCAFNY-----------------------A-D..HILTSDWIVDS..FK
M7T0V6_EUTLA/570-672-------------RTVK-------------FLRNLSK-----------------------G-A..TVVSSDWIEEC..LD
S3BRI5_OPHP1/687-789-------------RTMK-------------FLKTLAR-----------------------G-P..QVINAQFITDV..LE
G3AYG3_CANTC/572-676-------------RTEK-------------FLSSLGK-----------------------V-D..FILHPRLLIDLKYLL
G8YB77_PICSO/622-730-------------RTAK-------------FLKALSK-----------------------A-K..RIVHPNFLIDI..LR
F0U567_AJEC8/604-706-------------RTHK-------------FVNAIAY-----------------------A-P..VILNADFVAAC..LE
S9VT84_SCHCR/649-743-------------RTAK-------------FLCAIPK-----------------------G-P..QVVTMEWLQDS..IK
W1Q8C3_OGAPD/435-537-------------RTEK-------------FLKSLSK-----------------------S-P.KYLLTPMFLIDV..LA
G2YB22_BOTF4/618-722-------------RTRK-------------FLVGLAH-----------------------G-P..TVVSEKYIEAC..IK
M7PGB1_PNEMU/569-665-------------RTQK-------------FLSALSY-----------------------A-P..KILSVDWIKAC..LK
M1VXB8_CLAP2/609-711-------------RTVK-------------FLCSLAR-----------------------G-A..VVLSSEFVETV..LE
N1QC64_PSEFD/642-743-------------RTKK-------------FVCALAG-----------------------A-P..LVVDTSFLDTA..LT
Q5ALY1_CANAL/652-759-------------RTEK-------------FLRSLSK-----------------------V-D..KIIHPNYLVNI..IN
G2WSE1_VERDV/588-690-------------RTVK-------------FLRTLAK-----------------------G-V..TILSSDFIETA..LT
G0VDU3_NAUCC/653-763-------------RTAK-------------FLMSLSF-----------------------H-PLKYALLPDFITDV..LK
F9X0T3_ZYMTI/525-626-------------RTRK-------------FVCALAC-----------------------A-P..LVVDTTFLDSA..LK
Q6FR08_CANGA/839-955-------------RTVK-------------FLKSLSL-----------------------S-SIRYFLTPDYITAL..LL
H2AVG7_KAZAF/692-804-------------RTEK-------------FLRSLAF-----------------------H-PLKFALLPEFVTDL..LE
G8JP23_ERECY/643-750-------------RTAK-------------FLKSFSF-----------------------R-PLKYALIPKFINDV..LS

PF12738

MCPH1_HUMAN/9-75--------------------
ECT2_MOUSE/179-242--------------------
A2R3M9_ASPNC/121-184--------------------
A7F1C2_SCLS1/119-182--------------------
A7S5M3_NEMVE/449-511--------------------
A9RB53_PHYPA/468-530--------------------
B0DMV8_LACBS/502-564--------------------
B2VU23_PYRTR/350-412--------------------
B2W796_PYRTR/229-291--------------------
B2W7P6_PYRTR/114-177--------------------
B3RL44_TRIAD/702-764--------------------
B4H593_DROPE/186-250--------------------
B4KSD3_DROMO/76-140--------------------
B6HL54_PENCW/128-191--------------------
B6Q6C3_PENMQ/111-174--------------------
C0NFA4_AJECG/121-184--------------------
C1FFW2_MICSR/561-624--------------------
C4M4C9_ENTHI/17-80--------------------
C5FMN4_ARTOC/111-174--------------------
RAD4_SCHPO/105-167--------------------
Q16W28_AEDAE/219-283--------------------
Q1K5Z2_NEUCR/339-401--------------------
Q2H787_CHAGB/324-387--------------------
Q4CP92_TRYCC/1-63--------------------
A0A0D1CFS9_USTMA/599-667--------------------
Q5TRD6_ANOGA/110-173--------------------
Q6CN34_KLULA/351-414--------------------
PAXI1_MOUSE/102-165--------------------
Q6Z553_ORYSJ/10-72--------------------
Q9U7D8_DROME/117-180--------------------
B9GSH3_POPTR/111-175--------------------
D7SMI0_VITVI/4-66--------------------
F4I701_ARATH/188-251--------------------
F4I701_ARATH/667-729--------------------
F6XFW7_XENTR/204-267--------------------
H0ZRM8_TAEGU/5-67--------------------
H3C8W0_TETNG/80-141--------------------
I1QYC0_ORYGL/209-271--------------------
I1QYC0_ORYGL/675-736--------------------
Q4WQC2_ASPFU/345-407--------------------
Q7JUM5_DROME/187-251--------------------
U5GIH0_POPTR/4-66--------------------

PF00533

Y4211_ARATH/1089-1168--------------------
MDB1_SCHPO/384-455--------------------
MDB1_SCHPO/485-573--------------------
ECT2_MOUSE/266-341--------------------
PAXI1_HUMAN/701-776--------------------
PAXI1_HUMAN/860-934--------------------
TDT_HUMAN/27-111--------------------
RAD9_YEAST/994-1109--------------------
XRCC1_HUMAN/538-616--------------------
Q93161_CAEEL/981-1063--------------------
PARP4_HUMAN/1-81--------------------
TOPB1_HUMAN/101-176--------------------
TOPB1_HUMAN/195-271--------------------
TOPB1_HUMAN/354-431--------------------
TOPB1_HUMAN/548-620--------------------
TOPB1_HUMAN/641-725--------------------
TOPB1_HUMAN/900-978--------------------
TOPB1_HUMAN/1260-1338--------------------
Q20129_CAEEL/451-529--------------------
Q20129_CAEEL/587-659--------------------
Q20129_CAEEL/679-749--------------------
DNLJ_HAEIN/592-668--------------------
DNLI4_CANAL/673-756--------------------
Q20129_CAEEL/128-204--------------------
O76369_CAEEL/929-1023--------------------
PAXI1_MOUSE/588-668--------------------
PARP1_MOUSE/385-463--------------------
DNLI4_HUMAN/654-730--------------------
DNLI4_HUMAN/814-898--------------------
O16568_CAEEL/1044-1144--------------------
TDT_MONDO/27-111--------------------
O16229_CAEEL/378-460--------------------
DNLJ_HELPY/577-652--------------------
DNLJ_BACSU/590-666--------------------
DNLJ_MYCLE/607-683--------------------
O44844_CAEEL/154-256--------------------
DNLJ_BORBU/583-659--------------------
BRCA1_RAT/1588-1669--------------------
BRCA1_RAT/1701-1787--------------------
RFC1_SCHPO/236-313--------------------
DNLJ_AQUAE/619-696--------------------
CHS5_CANAL/164-246--------------------
DNLJ_TREPA/562-642--------------------
DNLJ_CHLTR/581-657--------------------
O96271_PLAF7/208-298--------------------
PESC_LEIMA/317-390--------------------
DNLJ_ECOLI/593-669--------------------
PARP1_CHICK/382-460--------------------
DNLJ_THET8/589-664--------------------
DNLJ_ZYMMO/645-721--------------------
RAD4_SCHPO/2-79--------------------
RAD4_SCHPO/392-473--------------------
RFC1_DROME/232-309--------------------
TDT_CHICK/27-111--------------------
BRCA1_HUMAN/1642-1723--------------------
BRCA1_HUMAN/1756-1842--------------------
RFC1_YEAST/153-230--------------------
RT107_YEAST/2-103--------------------
RT107_YEAST/117-213--------------------
RT107_YEAST/261-352--------------------
RT107_YEAST/370-453--------------------
YPT4_CAEEL/930-1012--------------------
YPT4_CAEEL/1049-1141--------------------
DPB11_YEAST/111-207--------------------
DNLJ_SYNY3/591-667--------------------
RHP9_SCHPO/535-640--------------------
FCP1_YEAST/499-580--------------------
DNLI4_YEAST/681-767--------------------
DNLI4_YEAST/836-928--------------------
Q09615_CAEEL/251-326--------------------
BRC1_SCHPO/14-91--------------------
BRC1_SCHPO/105-183--------------------
BRC1_SCHPO/216-293--------------------
BRC1_SCHPO/311-386--------------------
CHS5_YEAST/166-249--------------------
XRCC1_MOUSE/315-390--------------------
Q94046_CAEEL/514-600--------------------
Q94046_CAEEL/620-694--------------------
DNLJ1_STRCO/643-719--------------------
DNLJ_RICPR/610-686--------------------
PARP1_ARATH/394-471--------------------
D0MI04_RHOM4/636-709--------------------
H9KXM3_CALJA/403-478--------------------
Q5AZH7_EMENI/325-400--------------------

PF16589

K3WDG2_PYTUL/626-709GAMK----L..E.DDV.KYG
A2GB92_TRIVA/56-149AKQQ----I..L.DPS.PYF
E4V0Q5_ARTGP/707-798EQNE----LD.T..GE.DDV
H6BN77_EXODN/749-843EQAK----KDFA.KGY.PEM
D7MMS2_ARALL/654-741SRNK----M..L.PLQPKYF
D7SQI2_VITVI/653-740SQKK----L..L.PLQPKYF
M0S2G9_MUSAM/640-728KQKR----L..L.HLQPKYF
K7LC24_SOYBN/506-593EQKK----L..V.CLQPKYF
Q5KPS9_CRYNJ/138-224RQDK----L..L.DWR.KWR
A8WS89_CAEBR/455-544KKRK----L..V.NSE.DFH
H2ANJ1_KAZAF/685-782ENKK----I..V.KIE.PSH
I1BS31_RHIO9/47-133KEQD----L..L.NIE.PKY
I2H6P9_TETBL/707-804QAGV----I..L.PLE.PAH
D2V2T9_NAEGR/209-297RESR----L..I.PIS.EKI
D8M2G5_BLAHO/342-422KANR----L..V.PRN.EKV
G8BNV8_TETPH/119-211KKGQ----I..V.PIG.EHE
M2N998_BAUCO/197-300KAGK----R..L.PES.RFE
M2ZQ43_PSEFD/117-220KAGK----R..L.PES.RFE
V4Z6W2_TOXGO/178-272DRGK----L..L.PAS.NFR
A3LW54_PICST/41-121RLVT----L..Q.DIR.IYS
G3AM46_SPAPN/45-124NQGR----L..V.NLD.SFR
M3K224_CANMX/72-151ANGG----L..V.PLL.DYG
Q59XT2_CANAL/89-168AKNQ----L..L.SVF.DYG
A5DYD1_LODEL/66-146LAGT----L..L.PSH.NYV
G8BJX2_CANPC/111-190SVGQ----L..L.PFE.GYT
C4R0P7_PICPG/22-117TEGI----V..L.PLE.NYT
C4VBY8_NOSCE/44-123RLKK----L....NVE.NYI
R4XAV8_TAPDE/3-87REGQ----L..Q.NPE.YYV
A7EAG9_SCLS1/12-89KAGK----L..V.DME.AYR
G2YA12_BOTF4/12-89RAGK----L..V.DMD.EYR
E3QRM6_COLGM/14-92DNGA----I..Q.ETD.KYL
H1V395_COLHI/14-91DNGA----L..Q.ETD.KYL
L2G6F7_COLGN/14-91QYGA----M..Q.EED.KYQ
E3S9F7_PYRTT/19-96KQGE----L..A.NPD.DHI
G2QX03_THITE/15-91AKGE----L..L.NIE.DYQ
E9CWR8_COCPS/8-85RAGK----L..L.DLE.EFR
N1JJ21_BLUG1/13-90ERGY----L..Q.DVN.DHL
M5BM65_THACB/48-146KRGS----L..VPPLE.SLL
A7TGW3_VANPO/860-963SECV----Q..V.PEE.DYP
E3LW19_CAERE/691-776SRGS----L..L.PIN.NYL
A7TIC7_VANPO/66-154QNNT----L..L.NID.NYL
G8C1X2_TETPH/45-136QNNT----L..L.EAH.DYL
E7Q896_YEASB/122-207QSNS----L..L.NME.NYL
H2APC0_KAZAF/72-157QSKK----R..L.DIG.NYL
G0VI01_NAUCC/119-206SNNT----L..L.NIN.HYL
C5DTR6_ZYGRC/67-154QNGT----L..L.DIG.NYL
J7S744_KAZNA/61-148KSNT----L..L.SYN.RYI
F2Z6A0_CANGA/80-168QSNK----L..L.DMK.NYL
I2GXL7_TETBL/69-154NANT----L..L.EKD.QYL
G0WD26_NAUDC/165-250ARDT----L..L.PLE.NYL
G8ZLB0_TORDC/16-100ENGT----L..L.KIE.NYL
C5DD36_LACTC/53-131ENNV----L..M.KVQ.PFL
D3BEV4_POLPA/10-104EANR----L..L.SDD.RYQ
F0Z8S8_DICPU/18-113EKRY----LPLE.SVK.EFV
R0KT87_NOSB1/49-128YKLE----M..M.PIN.KYV
A8N1C0_COPC7/345-440RQEK----L..L.DHT.EFL
B0CPN9_LACBS/390-485ARET----L..IDDPT.PYL
V2XZF1_MONRO/81-173KEET----L..L.DYT.PYL
F8PP65_SERL3/410-502KEGV----V..L.DDA.EYV
K5W9L1_AGABU/439-532SQGG----M..PENLE.NYL
K5VDP9_PHACS/379-470AKGK----L..L.NSS.AYS
J4I894_FIBRA/337-429TEGS----I..L.DIE.PYS
M2QYA3_CERS8/374-465EEQT----L..V.EPD.GYG
A7RVV1_NEMVE/15-100HKNE----L..L.NIK.PYQ
B7QFB5_IXOSC/8-93KRDL----L..L.PLR.NFA
E9HFT5_DAPPU/11-109KCGD----L..L.DLE.RFR
E9HFT5_DAPPU/369-468KCGD----L..L.DLE.NFR
F1REC1_DANRE/34-120EQNQ----Q..L.DPN.DYA
W5K9C2_ASTMX/12-98TQNQ----Q..L.DMK.TYR
G3NA35_GASAC/14-100EKNE----Q..L.NLE.DYK
I3KA69_ORENI/14-100EKNE----Q..L.NLE.DYR
H2URR7_TAKRU/15-101KNNE----Q..L.DVE.SYR
H3DBF1_TETNG/17-103EKNE----Q..L.DLE.LYR
M4ASB2_XIPMA/13-99KKEE----Q..L.DLD.DYR
F6WSD5_XENTR/10-90RIDK----L..L.DVD.DYR
G5C0W9_HETGA/11-94ERKE----R..L.ELE.DYW
H3AZ34_LATCH/10-93SRNE----R..L.DLE.AYR
TE2IP_CHICK/5-85ESQR----R..L.PLD.LYR
W5N779_LEPOC/21-104GKNE----Q..L.EMH.DYK
B3RX95_TRIAD/6-86ANNA----L..Q.DIE.SYM
H3H3N9_PHYRM/2-81ASRA----L..Q.DPA.KYS
M4BMY6_HYAAE/1-80ASQS----L..Q.QLS.SYS
K3X8H7_PYTUL/34-113RDQV----L..Q.DVH.QYM
D2V2T9_NAEGR/8-105KENK----L..C.DEE.NFL
K0KC61_WICCF/18-95EQKS----L..L.KVD.NYK
K1VGF5_TRIAC/277-367RAGK----L..L.PTR.SYS
I7MFY6_TETTS/273-374SKGQ----L..L.NYK.NYT
D8M843_BLAHO/73-162ENKS----L..Q.PFS.KYS
D1ZZU6_TRICA/469-555NNKK----F..V.STV.DYL
F1N2F9_BOVIN/552-641EKQK----L..L.PHQ.LYG
H9G8R9_ANOCA/562-651ERQK----L..I.PHQ.PYV
G4VGJ3_SCHMA/541-631RSGQ----L..E.AYE.QYQ
A0A068XE55_HYMMI/504-594KAGK----C..V.PYQ.RYQ
H2ZBQ2_CIOSA/420-509QAVS----L..L.PCT.MYT
W5JUY9_ANODA/538-620EMEC----F..I.PVD.RYL
F4PQL1_DICFS/4-97TYQR----V..L.PVE.YYL
K1PXK2_CRAGI/835-912TQNR----V..M.SMD.SYL
Q5KDC9_CRYNJ/1333-1431EKGE----L..L.DVK.RYL

PF16759

H2ZXR2_LATCH/884-956KKRR----V-----------
F6S783_MACMU/933-1005RKRR----L-----------
D2W3T0_NAEGR/824-906NTST----L-----------
H3CY38_TETNG/809-881RKRR----V-----------
G3QCE5_GASAC/909-981RKRR----I-----------
Q1RL58_CIOIN/781-858KNKV----S-----------
E0VGK6_PEDHC/807-896KLLD----K-----------
H0Z3J4_TAEGU/853-925RKRR----L-----------
H2MK50_ORYLA/283-355RKRR----V-----------
C3XPG8_BRAFL/848-925KRKQ----L-----------
D6WBL1_TRICA/353-434AEEN----L-----------
F2US92_SALR5/1151-1238KRRT----R-----------
D6WBL2_TRICA/760-840VNES----V-----------
H2Z1K6_CIOSA/772-849QNEN----T-----------
A0A0D2X4A3_CAPO3/1228-1306AAG.----.-----------
F6WXI9_XENTR/905-977RRRR----.-----------
J9JUI3_ACYPI/779-867RKGT----.-----------

PF16770

Q0TZK5_PHANO/609-711........NNKLPPPEKHIL
C4R1B3_PICPG/699-801AKQ.....EQDLPELEEYSI
G2QHK9_THIHA/602-704........TGKRPPIKDHLL
M3JFE1_CANMX/645-749AEKVEDI......KIEDYSL
E9CRG1_COCPS/597-699........KDELLDPNKYKL
M2M1A3_BAUCO/659-760........QNKLVD.DPKLL
G4NCT3_MAGO7/597-703........NGELPNVEDYPL
F2SLK3_TRIRC/597-699........KKELLDPNDYIL
R8BK69_TOGMI/621-723........TGKVPAIEKYKL
S3D3M8_GLAL2/608-712........KGGPPDIEDYVL
C7YM63_NECH7/596-698........MGKLPDIDEYIL
C4JTM0_UNCRE/600-702........KDKLLDPDKYKL
C8V3U9_EMENI/593-695........KNKLLDPEDFLL
Q6BZF3_DEBHA/634-743KLNSSQDADGDQ.VSKEFSI
I1RVV5_GIBZE/601-703........TGNLPDVEGFIL
L8WY45_THACA/745-841........EGKLQDEAEYKL
C5DS98_ZYGRC/912-1023IIHKGKKANLSL.DISRYYI
K5WLU5_PHACS/1099-1194........KKSIQPEAPFAL
Q75AR5_ASHGO/635-742LVHSGRNEPISL.PLEQYYI
B6K613_SCHJY/586-680........RHSVQDEKPYFL
G0W9V9_NAUDC/944-1052ALRQGKRKD....DKKNHHY
I2GZK5_TETBL/782-893IINGKKSGSIKL.PFEKYQI
N1JBZ0_BLUG1/603-705........LNSIPDVNDYLL
E9EQX4_METRA/605-707........TGDVPDVDDFIL
G3MZP9_BOVIN/976-1073........CQKFVDEQNYLL
Q6CN34_KLULA/656-761NINKEKPVEL...EMSKYFI
L2GJC4_COLGN/595-697........KGEAPDPEDFLL
T5A5F6_OPHSC/606-708........SGQVPATDEYVL
N1Q1B5_DOTSN/497-598........KKKLQE.DPPML
L0PC51_PNEJ8/4-94........EKKIIDENAYFL
G3AMT0_SPAPN/577-678NVDKQT.......VLTEFNI
I2H240_TETBL/888-996VISQGKQVNYIL.NLEKYRL
C5M5V1_CANTT/627-732HVKDKGKS.....VLKEYRI
G8BF53_CANPC/627-730NAENNGD......VLSLYRI
A5DUV3_LODEL/733-836NIENTDN......VRLRYNV
H6BTR1_EXODN/609-711........ENKLLNPEDFLL
A7TEV9_VANPO/803-912RIHHRKPASIEF.DLSQFTI
D5G6X4_TUBMM/591-693........EEKIVDTEPYLL
J3P060_GAGT3/622-731........TGELPNIEEYAL
G1X016_ARTOA/638-741........QKAIVDTKPYLL
J7R641_KAZNA/728-836AVSRGASFPL...DFERYVI
A5DNV2_PICGU/524-631VVNESSTWES...INKQFKM
BRC1_SCHPO/650-744........THEIVDEEPYLL
G0S8X0_CHATD/601-703........KGKRPNVDDYRL
B6K1B2_SCHJY/418-515........ANKKLAEEDFVL
R7YHQ6_CONA1/603-705........WGRIPDPANFKL
S6EZG3_ZYGB2/878-989IIHKNKRADLQL.DLSKYYI
C5DDJ9_LACTC/677-784IFRQTTPIQ.ELPKPEDYLI
RT107_YEAST/820-925QIHSKKD......KLSQINI
T1K2U0_TETUR/823-921........RSHLLDESQYIL
M7T0V6_EUTLA/570-672........TKKVLDPKSYLL
S3BRI5_OPHP1/687-789........KGKLLDTKEYAL
G3AYG3_CANTC/572-676GRGESPEI.....EIQDYRL
G8YB77_PICSO/622-730AKKNSTDYESEL..LNNFPI
F0U567_AJEC8/604-706........QNQLLNPNEFLL
S9VT84_SCHCR/649-743........HRHPSLESEYLL
W1Q8C3_OGAPD/435-537TVH.....SHKLDDFEHFKP
G2YB22_BOTF4/618-722........AGKMLDVEDFPL
M7PGB1_PNEMU/569-665........ERKIMDENNYFL
M1VXB8_CLAP2/609-711........TGEIPDVNDFIL
N1QC64_PSEFD/642-743........KKKLIE.DPHML
Q5ALY1_CANAL/652-759HISSKGDTET...VFKEYRI
G2WSE1_VERDV/588-690........DGTAPDPKDHIL
G0VDU3_NAUCC/653-763FVHRGES.PMELMNLDDYRI
F9X0T3_ZYMTI/525-626........HKKLAA.DPPML
Q6FR08_CANGA/839-955DIKSGK.......DVSKYRS
H2AVG7_KAZAF/692-804KLHNREN.PSEL.NIKQYFI
G8JP23_ERECY/643-750IVHSGSGASVLL.SLEEYHI

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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