Sequence alignment for CL0461

PF05522

MTA_STRPU/2-64-PDV-KCVCCKEG-------------------KECACFGQDCCK-------------TGECCK-DG..TCCG.....ICT
MTB_SPHGR/3-67-PDV-KCVCCQDG-------------------EECPCKGGECCI-------------TGTCCK-EGDGLCCG.....KCS
MT_LYTPI/4-68-PDV-KCFCCRDG-------------------KECACGGGECCI-------------TGKCCK-EGDRTCCG.....KCS
O76953_9ANNE/3-73-CCG-FDACPRRG-------------------AACAC.TNCRCL-------------KSECSP-NYRKLCCADS.QGKCG
MT_EISFE/4-75-CCG-KSTCAREG-------------------STCCC.TNCRCL-------------KSECLP-GCKKLCCADAEKGKCG
Q9GRJ0_LUMRU/9-77-CCG-NKTCPREG-------------------STCAC.SKCRCP-------------KDDCLP-NCKKLCCADA...QCG
Q966Z5_PARLI/2-66-PDT-KCVCCQDG-------------------KQCPCAGQECCI-------------TGKCCK-DGASVCCG.....TCS

PF12749

Q231A6_TETTS/1-105-MDT-QTQTKVTVGCSC...............NPCKCQPLCKCGTTAACNCQPCENCDPCSCN-PCK..CGATE---SCG
K1PN32_CRAGI/1-107-MSD-PCNCTATGTCVC.........SDSCPATGCKCGPGCKCG.............DGCKCS-GCKVKCNCSG---SCG
ZYM1_SCHPO/1-49-MEH-TTQCKSKQG..................KPCDCQ...................SKCGCQ-DCK......E---SCG
Y7870_DICDI/1-51-MTH-S............................CKCGDSCQCG.............DKCTCG-PKE.....TP---KCG
B3LVP3_DROAN/1-69-MFN-AKLFVLLTVALCLVQSCTIDEPEPEPEAPCKCGKP.................DGSSCG-AVK.....SS---GCG

PF00131

MT3_BOVIN/1-68-MDPETCPCPT.G-------------------GSCTCSDPCKC--------------EGCTCA-SSKKSCCSCC---PAE
MT4_CANFA/1-62-MDPGECTCMS.G-------------------GICICGDNCKC--------------TTCNCK-TCRKSCCPCC---PPG
MT2C_RABIT/1-62-MDP.NCSCATAG-------------------DSCTCANSCTC--------------KACKCT-SCKKSCCSCC---PPG
F6PZ48_MACMU/1-61-MDP.NCSCAT.D-------------------VSCACAGSCKC--------------KECKCT-SCKKSCCFCC---PVG
Q9NG19_CRAGI/2-66-SDP..CNCTE.T-------------------GTCVCSDSCPA--------------TGCKCG-PGCKCGDGCK---CSG
U3JYH7_FICAL/2-63-.DSQDCPCAT.G-------------------GTCTCGDNCKC--------------KNCKCT-SCKKGCCSCC---PAG
W5K846_ASTMX/1-60-MDP..CDCAK.T-------------------GSCNCGASCKC--------------TNCQCT-TCQKSCCPCC---PSG

PF12809

CRS5_YEAST/1-69-MTV----------------------------KICDCEGECCK--------------DSCHCGSTCLPSCSGGE---KCK
J5RII1_SACK1/1-69-MAV----------------------------KKCACENECCK--------------DSCKCGATCVKNCVGGK---KCK
J8PI13_SACAR/1-69-MTV----------------------------KKCACKDECCR--------------DSCKCGTDCVPSCSGNE---KCR

PF11403

MTCU1_YEAST/9-47-QNE--------G-------------------HECQC-----------------------QCG--------------SCK
J4U064_SACK1/9-47-QNE--------G-------------------HECQC-----------------------QCG--------------SCK

PF02069

K9U5A2_9CYAN/12-63TVTS----------------------------MKCAC--------------------DNCLCVVSLEDAIQKDG---KAY
Q8DK53_THEEB/3-54TVTQ----------------------------MKCAC--------------------PHCLCIVSLNDAIMVNG---KPY
K9RIA9_9CYAN/3-53AVDL----------------------------MKCAC--------------------DKCLCIVKVETAIDRDG---KHY
K9S806_9CYAN/3-53TVTQ----------------------------MKCAC--------------------ESCLCVVNLSDAVHKDE---KYY
K9Z103_CYAAP/5-55TVTQ----------------------------MKCAC--------------------PSCLCIIDISQAISRDG---HYY
S6AIY4_PSERE/2-49..TE----------------------------QRCAC--------------------ASCSCVVD.ARALVRDG---KAY
K9PAC9_CYAGP/10-58...T----------------------------LQCAC--------------------PGCHCTVQEDSPFRNGA---LLF
K9PV70_9CYAN/3-53TATQ----------------------------LKCDC--------------------PNCTCMVDLASAVKKDG---KNY
K8GTB8_9CYAN/3-53TVTQ----------------------------MKCAC--------------------PDCLCIVNLSDAVMKDG---KAY
F2K9R9_PSEBN/2-50..SK----------------------------LKCGC--------------------PDCQCEVDPQRMFNHDG---EAY
B0UBD7_METS4/7-56.VEM----------------------------VKCAC--------------------EDCVCVVPLAKAVQHDG---RAY
B7KK77_CYAP7/3-53TVTQ----------------------------MKCAC--------------------ESCLCIVDLETAIKKDG---KSY
Q3J765_NITOC/6-52QSST----------------------------MKCAH--------------------APCSCVVTAEEGVKKDG---QVY
B7JYR9_CYAP8/5-55TVTQ----------------------------MKCAC--------------------SSCVCIVDLSDAIQKDG---KYY
A0ZMC0_NODSP/3-53TVTQ----------------------------MKCAC--------------------PTCLCIVSLEDAINKEG---KYY
MT_SYNE7/3-54STTL----------------------------VKCAC--------------------EPCLCNVDPSKAIDRNG---LYY
K9VK01_9CYAN/3-53TATQ----------------------------TKCAC--------------------PSCSCVVNVSEAIEKDG---KQY
D4ZYS3_ARTPN/3-53TVTQ----------------------------MKCAC--------------------ESCLCIVDTTKAIAKNG---QYY
K9YQD6_CYASC/3-53TVTQ----------------------------MKCAC--------------------PSCLCIVNLSDAIQKND---HYY
K9THX7_9CYAN/3-53TVTQ----------------------------MKCAC--------------------ESCLCVVPTDKAVMKDG---KPY
Q7NFU4_GLOVI/3-53TVTQ----------------------------MKCAC--------------------EACLCVVTLSEALEKDG---KYF
Q88HU1_PSEPK/2-49..ND----------------------------QRCAC--------------------THCSCTVD.ANALQRDG---KAY
K9XVF5_STAC7/3-53TVTS----------------------------MKCAC--------------------DRCLCVVSLEDAVKKDG---KYY
K9SJ94_9CYAN/24-77SATL----------------------------VKCAC--------------------SKCLCVIDPSDAIEANG---KYY
K9V6M1_9CYAN/3-53SVTL----------------------------MKCAC--------------------QTCLCVVSTQDAVQKDN---KYY
B1LW41_METRJ/6-55.VEM----------------------------VKCAC--------------------QDCVCVIPVAKAVSRDG---KAY
C5AVV7_METEA/6-55.VDM----------------------------VKCAC--------------------PDCVCVVSVTKAVKRDE---KAF
K9VWZ1_9CYAN/3-53TVTS----------------------------MKCAC--------------------DSCLCVVNIGEAIEKDE---KYY
K9T9H0_9CYAN/20-70TVTS----------------------------MKCAC--------------------ESCLCIVSLENALQKNG---KYY
Q7U999_SYNPX/2-52.STA----------------------------IKCAC--------------------PKCTCMVAEESAIVLQG---KFF

PF05522

MTA_STRPU/2-64N-------AACKCAN-----------------------GCKCGSG...CSC---TEGNCAC-
MTB_SPHGR/3-67N-------AACKCAD-----------------------GCKCGSG...CSC---TLGNCTC-
MT_LYTPI/4-68N-------AACKCAD-----------------------GCKCEGA...CAC---TMGNCTC-
O76953_9ANNE/3-73N-------AGCKCGA-----------------------ACKCAAGACASGC---KKGCCGD-
MT_EISFE/4-75N-------AGCKCGA-----------------------ACKCSAGSCAAGC---KKGCCGD-
Q9GRJ0_LUMRU/9-77N-------AGCSCGA-----------------------ACKCAAGSCASGC---KKGCCAD-
Q966Z5_PARLI/2-66N-------AACKCTG-----------------------GCKCEGG...CQC---TEGNCTC-

PF12749

Q231A6_TETTS/1-105C.......NPCKCAECKCGSHTEKTSACKCNPCACNPCNCGSTSN---CKC...NPCKCAE-
K1PN32_CRAGI/1-107CGKGCTGPENCKCANDSECGCKVKCNCSGSCGCGK...GCTGPES---CKCANDSGCGCKK-
ZYM1_SCHPO/1-49C.....................................KSSAVDN---CKC...SSCKCAS-
Y7870_DICDI/1-51C.......SDCKCGD.......................KCSS..D---CKC...TSCTCKK-
B3LVP3_DROAN/1-69C.......KPCRCG...............................---CPC...RSCSNVD-

PF00131

MT3_BOVIN/1-68C------...EKCAK-----------------------DCVCKGGE--GAEAEEKKCSCCQ-
MT4_CANFA/1-62C------...AKCAQ-----------------------GCICKG..--....GSDKCSCCA-
MT2C_RABIT/1-62C------...AKCAQ-----------------------GCICKG..--..ASD..KCSCCA-
F6PZ48_MACMU/1-61C------...AKCAQ-----------------------GCVCKE..--....ASEKCSCCA-
Q9NG19_CRAGI/2-66C------KVKCNCSG-----------------------SCGCGK..--.GCTGPENCKCA.-
U3JYH7_FICAL/2-63C------...AKCAQ-----------------------GCVCKG..--.PPSA..KCSCCK-
W5K846_ASTMX/1-60C------...SKCAS-----------------------GCVCKG..--.NA...CGSSCCQ-

PF12809

CRS5_YEAST/1-69CDHSTGSPQCKSCGE-----------------------KCKCETT---CTC-EKSKCNCEKC
J5RII1_SACK1/1-69CDHNPESSQCKSCGE-----------------------NCRCGTT---CVC-EKSKCSCEKC
J8PI13_SACAR/1-69CDHNSESTQCNNCGE-----------------------SCKCGAT---CTC-EKSKCTCEKC

PF11403

MTCU1_YEAST/9-47N--------NEQCQK-----------------------SCSCP-----TGCNSDDKCPCG--
J4U064_SACK1/9-47N--------NKQCQK-----------------------SCRCP-----IGCNSDDKCPCG--

PF02069

K9U5A2_9CYAN/12-63C--------SEACAS-------------------------GHPDGS..SGC.GHTGCGC---
Q8DK53_THEEB/3-54C--------SEVCAN-------------------------GTCKEN..SGC.GHAGCGC---
K9RIA9_9CYAN/3-53C--------SEACAE-------------------------GHKTI...TGC.GHSGCGC---
K9S806_9CYAN/3-53C--------CEACAN-------------------------GHQSG...DGC.GHSGCGC---
K9Z103_CYAAP/5-55C--------STACAE-------------------------GHKEG...EGC.GHSGCGC---
S6AIY4_PSERE/2-49C--------CAACAD-------------------------GHKDG...EPC.HETGCHC---
K9PAC9_CYAGP/10-58C--------SEVCAK-------------------------GHPNG...EPCHASCGCEC---
K9PV70_9CYAN/3-53C--------STTCAN-------------------------GHPEG...GCC.AESSCSC---
K8GTB8_9CYAN/3-53C--------GEACAN-------------------------GHPEG...AGC.GHTGCGC---
F2K9R9_PSEBN/2-50C--------SQACAE-------------------------QHPNG...EPC.PAPDCHC---
B0UBD7_METS4/7-56C--------CDECAT-------------------------GHPDH...AGC.GHAGCTC---
B7KK77_CYAP7/3-53C--------SEACAN-------------------------GHPEG...SGC.GHQGCGC---
Q3J765_NITOC/6-52C--------SEACAR-------------------------E.......QGC.EHGACAC---
B7JYR9_CYAP8/5-55C--------SDACAN-------------------------GHPDG...AGC.SHHGCEC---
A0ZMC0_NODSP/3-53C--------SEGCAE-------------------------GHKTI...KGC.GHNGCGC---
MT_SYNE7/3-54C--------SEACAD-------------------------GHTGGS..KGC.GHTGCNC---
K9VK01_9CYAN/3-53C--------SSACAD-------------------------GHPNG...QGC.GHTGCEC---
D4ZYS3_ARTPN/3-53C--------SEACAN-------------------------GHPNG...DGC.GHKGCNC---
K9YQD6_CYASC/3-53C--------CQACAD-------------------------GHPNG...SGC.GHTGCGC---
K9THX7_9CYAN/3-53C--------SDACAN-------------------------GHVDG...TGC.GHSGCDC---
Q7NFU4_GLOVI/3-53C--------SGPCAN-------------------------GHPDG...SGC.GHTGCEC---
Q88HU1_PSEPK/2-49C--------CEACAS-------------------------GHRKG...EPC.RMQDCHC---
K9XVF5_STAC7/3-53C--------CEACAN-------------------------GHTDG...SGC.GHQGCGC---
K9SJ94_9CYAN/24-77C--------CKACAS-------------------------GHVDGTNDSHC.SDVGCEC---
K9V6M1_9CYAN/3-53C--------SPACAE-------------------------GHKTM...KGC.ANSGCGC---
B1LW41_METRJ/6-55C--------CDDCAD-------------------------GHKDH...AGC.EHAGCAC---
C5AVV7_METEA/6-55C--------CDECAE-------------------------GHPDH...AGC.DHAGCSC---
K9VWZ1_9CYAN/3-53C--------SQPCAN-------------------------GHADG...EGC.GHSGCGC---
K9T9H0_9CYAN/20-70C--------CEACAD-------------------------GHVNE...KGC.GHTGCTC---
Q7U999_SYNPX/2-52C--------STSCST-------------------------GHANN...EPCHGEGSCGC---

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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