Sequence alignment for CL0461

PF12809

COLL1_HUMAN/39-118---CIRN--QDCE--TGCCQRAPDNCESHCAEKGSEGSLCQ-TQVFFGQYRACPCLR-----------------------
CRS5_YEAST/2-69---TVKI--CDCE--GECCKDSC.HCGSTCLPSCSGGEKCK-CDHSTGSPQCKSCGE-----------------------

PF02069

Q0I7F0_SYNS3/1-55MTTNLVR--CDCP----PCTC---SIE-EATAAMYGNKLFC-SE-------ACATAH-----------------------
Q7NFU4_GLOVI/2-53TTVTQMK--CACE----ACLC---VVT-LSEALEKDGKYFC-SG-------PCANGH-----------------------
A0ZMC0_NODSP/2-53NTVTQMK--CACP----TCLC---IVS-LEDAINKEGKYYC-SE-------GCAEGH-----------------------
Q0I7J7_SYNS3/2-51ATSNQV.--CACD----PCSC---AVS-VESAVQKDGKVYC-SQ-------PCADGH-----------------------
Q3M1A6_ANAVT/7-58TTVTQMK--CACP----SCLC---VVS-LTDAVIKDGKAYC-GE-------ECANNH-----------------------
Q88HU1_PSEPK/1-49M..NDQR--CACT----HCSC---TVD-.ANALQRDGKAYC-CE-------ACASGH-----------------------
Q83V98_9CYAN/2-53TTVTQIK--CACP----SCLC---VVS-LTEAIEKSGKSYC-SS-------ACADGH-----------------------
MT_THEVL/2-54TTVTQMK--CACP----HCLC---IVS-LNDAIMVDGKPYC-SE-------VCANGT-----------------------
Q3J765_NITOC/5-52TQSSTMK--CAHA----PCSC---VVT-AEEGVKKDGQVYC-SE-------ACAREQ-----------------------
Q0IB79_SYNS3/1-56MTVTVVK--CACS----SCTC---EVS-SSSAISRNGHSYC-SD-------ACASGH-----------------------
A0YTD8_LYNSP/2-53SAVTQMK--CACE----SCLC---VVS-LENAIKKDGKPYC-SE-------ACANGH-----------------------
Q7U999_SYNPX/2-52S..TAIK--CACP----KCTC---MVA-EESAIVLQGKFFC-ST-------SCSTGH-----------------------
MT_SYNSP/1-53TSTTLVK--CACE----PCLC---NVD-PSKAIDRNGLYYC-CE-------ACADGH-----------------------

PF05522

MTA_STRPU/2-64---PDVK--CVCCKEGKECACFGQDCC-KTGECCKDG..TC-CG--.....ICTNAA-----------------------
MTB_SPHGR/3-67---PDVK--CVCCQDGEECPCKGGECC-ITGTCCKEGDGLC-CG--.....KCSNAA-----------------------
MT_LYTPI/4-68---PDVK--CFCCRDGKECACGGGECC-ITGKCCKEGDRTC-CG--.....KCSNAA-----------------------
O76953_9ANNE/3-73---CCGF--DACPRRGAACAC.TNCRC-LKSECSPNYRKLC-CA--DS.QGKCGNAG-----------------------
MT_EISFO/4-75---CCGK--STCAREGSTCCC.TNCRC-LKSECLPGCKKLC-CA--DAEKGKCGNAG-----------------------
Q9GRJ0_LUMRU/9-77---CCGN--KTCPREGSTCAC.SKCRC-PKDDCLPNCKKLC-CA--DA...QCGNAG-----------------------
Q966Z5_PARLI/2-66---PDTK--CVCCQDGKQCPCAGQECC-ITGKCCKDGASVC-CG--.....TCSNAA-----------------------

PF12749

Q7K5Q2_9HYMN/1-96MDTQ-----TQTKL-TTACKCNP-CKC-QPLCKCGTTSACN-CQPCENCDPCSCNPCKCGTSDACKCNPCKCTDCKCAAS
Q697L8_MYTGA/1-72MAGP-----CNCIA-TNVCICGT-GCS-EKCCQCG..DACK-CE.....SGCGCSGCKV.....................
ZYM1_SCHPO/1-50MEHT-----TQ...-........-...-...CKSKQGKPCD-CQ.....SKCGCQDCKE.....................
Y7870_DICDI/1-51M...-----.....-THSCKCGD-S..-...CQCG..DKCT-CGPKET.PKCGCSDCKC.....................

PF00131

MT3_BOVIN/1-68MDPET....CPCPT.GGSCTCSD.PCK.CEGCTCASSKKSC.CS-------CCPAEC..---------------------
MT23A_MYTGA/2-67PGP......CNCIE.TNVCICGT.GCS.GKCCQCGDACKCA.SG-------CGCSGCKV---------------------
MT10A_MYTED/2-68PAP......CNCIE.TNVCICDT.GCS.GEGCRCGDACKCSGAD-------CKCSGCKV---------------------
MT_CRAVI/2-69SDP......CNCIE.TGTCACSD.SCP.ATGCKCGPGCKCG.DD-------CKCAGCKV---------------------
MT1_CALSI/2-58PGPCCN.DKCVCQE.G...GCKA.GCQ.CTSCRCSPCQKCT.SG-------CKCATK..---------------------
Q9BIV4_CRAGI/2-67SDP......CNCIE.TGTCVCSE.SCP.ATGCKCGLGCKCG.DG-------CKCSGCKV---------------------
MT_RUTRU/1-60MDP......CDCAK.TGTCNCGA.TCK.CTNCQCTTCKKSC.CT-------CCPSGC..---------------------
MT4_CANFA/1-62MDPGE....CTCMS.GGICICGD.NCK.CTTCNCKTCRKSC.CP-------CCPPGC..---------------------
MT2_MESAU/1-61MDP.N....CSCAT.DGSCSCSG.SCK.CKECKCTTCKKSC.CS-------CCPVGC..---------------------
MT2_CALSI/2-58PDPCCN.DKCECKE.G...ECKT.GCK.CKSCRCPPCDKCS.SE-------CKCTSK..---------------------
MT_GADMO/1-60MDP......CDCAK.TGTCNCGT.SCT.CANCSCTKCKKSC.CE-------CCPSGC..---------------------
MT_XENLA/1-62MDPQD....CKCET.GASCSCGT.TCS.CSNCKCTSCKKSC.CS-------CCPAEC..---------------------
MT2C_RABIT/1-62MDP.N....CSCATAGDSCTCAN.SCT.CKACKCTSCKKSC.CS-------CCPPGC..---------------------
Q9U623_PACLE/2-58PGPCCN.DQCECAA.G...GCKT.GCV.CTSCRCQPCDKCT.SG-------CKCPSK..---------------------
MT_PERVI/2-68PSP......CNCIE.TQVCICGT.GCS.GEGCRCGDACKCS.SG-------CGCSGCKV---------------------
MT_DREPO/2-68SDP......CNCVE.TGDCRCADGSCSDCSNCKCGDSCKCS.KP-------NCCGKN.V---------------------
MT1_COLLI/1-63MDSQD....CPCAA.GGTCTCGD.NCK.CKNCKCTSCKKGC.CS-------CCPAGC..---------------------
MT_AMBME/1-60MD.......CACAT.GGSCSCAG.SCK.CENCKCTSCKKSC.CS-------CCPSEC..---------------------
MT_POTPO/1-58PDPCCAEGTCECEE.G...KCKA.GCK.CTSCRCSPCEKCT.SE-------CECKSK..---------------------
MT_ICTPU/1-60MDP......CECSK.TGTCNCGT.SCK.CSNCQCACCKKSC.CS-------CCPSGC..---------------------
MTA_CHAAC/1-60MDP......CECSK.SGNCNCGG.SCT.CTNCSCKSCKKSC.CP-------CCPSGC..---------------------

PF12809

COLL1_HUMAN/39-118-NLTCIYSKNEKWLSIAYGRCQKIGRQKLAKK----
CRS5_YEAST/2-69-KCKC........ETTC..TCEK.SKCNCEKC----

PF02069

Q0I7F0_SYNS3/1-55--.INQ--EPSNSA.E-------HTECSC-------
Q7NFU4_GLOVI/2-53--.PDG--SGC....G-------HTGCEC-------
A0ZMC0_NODSP/2-53--.KTI--KGC....G-------HNGCGC-------
Q0I7J7_SYNS3/2-51--SGSD--ECC.....-------.KSCDC-------
Q3M1A6_ANAVT/7-58--.PNG--QGC....G-------HTGCDC-------
Q88HU1_PSEPK/1-49--.RKG--EPC....R-------MQDCHC-------
Q83V98_9CYAN/2-53--.PNG--TGC....G-------HTGCEC-------
MT_THEVL/2-54--CKEN--SGC....G-------HAGCGC-------
Q3J765_NITOC/5-52--....--.GC....E-------HGACAC-------
Q0IB79_SYNS3/1-56--.RNN--EPCHDAAG-------ACGCNC-------
A0YTD8_LYNSP/2-53--.PNG--SGC....G-------HTGCTC-------
Q7U999_SYNPX/2-52--.ANN--EPCH...G-------EGSCGC-------
MT_SYNSP/1-53--TGGS--KGC....G-------HTGCNC-------

PF05522

MTA_STRPU/2-64--CKCA--NGCKCGSG...CSCTEGNCAC-------
MTB_SPHGR/3-67--CKCA--DGCKCGSG...CSCTLGNCTC-------
MT_LYTPI/4-68--CKCA--DGCKCEGA...CACTMGNCTC-------
O76953_9ANNE/3-73--CKCG--AACKCAAGACASGCKKGCCGD-------
MT_EISFO/4-75--CKCG--AACKCSAGSCAAGCKKGCCGD-------
Q9GRJ0_LUMRU/9-77--CSCG--AACKCAAGSCASGCKKGCCAD-------
Q966Z5_PARLI/2-66--CKCT--GGCKCEGG...CQCTEGNCTC-------

PF12749

Q7K5Q2_9HYMN/1-96AGCKCS--PCNCTD-C---KCTGTESC.CQK....Q
Q697L8_MYTGA/1-72.VCRCS--GTCACG-C---GCTGPTNCKCESGCSCN
ZYM1_SCHPO/1-50.SCGCK--SSAVDN-C---KCS...SCKCAS....K
Y7870_DICDI/1-51.GDKCS--S....D-C---KCT...SCTCK.....K

PF00131

MT3_BOVIN/1-68-.EKCA..KDCVCK-GGEGAEAEEKKCSCCQ-----
MT23A_MYTGA/2-67-VCRCS..GTCACG-C...DCTGPINCKCES-----
MT10A_MYTED/2-68-VCKCS..GRCECG-K...GCTGPSTCKCAP-----
MT_CRAVI/2-69-KCSCTSEGGCKCG-E...KCTGPATCKCGS-----
MT1_CALSI/2-58-.EECS..KTCTKP-...........CSCCP-----
Q9BIV4_CRAGI/2-67-KCNCS..GSCGCG-K...GCTGPENCKCAN-----
MT_RUTRU/1-60-.SKCA..SGCVCK-G......NSCGSSCCQ-----
MT4_CANFA/1-62-.AKCA..QGCICK-G......GSDKCSCCA-----
MT2_MESAU/1-61-.AKCS..QGCVCK-E....ASE..KCSCCA-----
MT2_CALSI/2-58-.EECS..KTCSKP-...........CSCCP-----
MT_GADMO/1-60-.SKCA..SGCACK-D......KTCDTNCCQ-----
MT_XENLA/1-62-.SKCS..QGCHCE-K....GSK..KCSCCN-----
MT2C_RABIT/1-62-.AKCA..QGCICK-G....ASD..KCSCCA-----
Q9U623_PACLE/2-58-.EECA..KTCSKP-...........CRCCP-----
MT_PERVI/2-68-VCKCQ.PGECACG-K...QCTGPDTCKCDS-----
MT_DREPO/2-68-TCKCG..ENCQCG-V...GCTGPDSCTCDS-----
MT1_COLLI/1-63-.AKCA..QGCVCK-G...PPSA..KCSCCK-----
MT_AMBME/1-60-.EKCG..QGCVCK-G...GSSE..KCSCCN-----
MT_POTPO/1-58-.EECA..KNCTKP-...........CSCCP-----
MT_ICTPU/1-60-.SKCA..SGCVCK-G......DTCDSKCCQ-----
MTA_CHAAC/1-60-.TKCA..SGCVCI-G......KTCDTSCCQ-----

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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