Sequence alignment for CL0466

PF04495

Q2LYW0_DROPS/69-205LTVYSSKTQTVRELTL.TP...............STSWGGQ.................GLLGVSIRF-CSF---------
Q0U7P0_PHANO/83-216LGVFSAKGQKIREVYISVP...............STN.....................PTLGISLQW-SPL---------
Q6BX19_DEBHA/130-306LDVWSAKGGIVRQVILPLDKFEPSSKDDADESELSLFNDSF.................SQVGLTLQS-QHL---------
A5DBW3_PICGU/154-329LDVWSAKGGIIRQVRLPLNKPDELKD.ETSVDSSKLFYGLF.................AEIGVVLSS-QHL---------
GORS2_MOUSE/69-205MLIYSSKTLELREASV.TP...............SNLWGGQ.................GLLGVSIRF-CSF---------
Q0IEU2_AEDAE/69-205MTVFSSKTQNIRVVNI.MP...............STTWGGQ.................GLLGVSIRF-CSF---------
Q5KDT5_CRYNJ/68-205LRVYNTKSQRVREA....................SKASGDPNA.............KPSLLGLSLRV-CNP---------
YAT2_SCHPO/80-213LEVFSLKGQITRKVNIKIN...............SDE......................KIGMVLQW-ASI---------
GORS1_MOUSE/68-204LEVFNMKTMKVREVEV.VP...............SNMWGGQ.................GLLGASVRF-CSF---------
Q4UCI6_THEAN/70-205LTVYNARKKNIRDVYI.VP................QKWDGI.................GLLGLTLKF-GLF---------
Q54C46_DICDI/73-210LIVYNIKSDTTREVSI.TP...............STTWGGQ.................GLAGISIRY-CSW---------
Q2UN33_ASPOR/80-214FEIWSAKGQKTHTASIPIS...............PSN.....................PTLGVALQL-APL---------
A7ARE9_BABBO/70-205LNVYNARQKSLRLIKI.TP................RKWDGV.................GLLGLSVRF-AEF---------
Q4Q3U9_LEIMA/103-265FTTFNLYSRTYRDVYC.VP...............SDEWGGG.................GLLGCSIEW-TRA---------
Q22G20_TETTS/89-227MVIYDILQRKIRIVKV.VP...............NKDWSNQ................QNLLGVMLRL-ENY---------
Q386P4_TRYB2/73-244LTVYNLYIHNYRDVHC.VA...............SSTWGGG.................GLLGCSVEW-CQA---------
Q4PFN7_USTMA/83-237LNVWNSKRQQLRQVSL.VP...............SREWSSQPSTSSINGTSSRATSQPSLLGLSLRL-CNP---------
Q2HFQ7_CHAGB/78-211LGLWSAKGQRTRALHVPVP...............ANT.....................ASLGLALQW-TPV---------
B0S774_DANRE/70-205MEVYSTKTMRMRELEV.VP...............SNMWGGQ.................GLLGASVRF-CSF---------
E7KBH0_YEASA/142-281.SIISKESDDLDDVSLNHDER..........RPSSGEAHQF.................QALGFKVQW-TPL---------

PF14685

TRIC_SULTO/556-640----------------------------------------------------------GGLGADYEY.DKE---------
TRI_THEAC/763-849----------------------------------------------------------GRIACDFKL.D..---------
Q4J6J4_SULAC/709-795----------------------------------------------------------GGLGAEFNY.D..---------
A5US97_ROSS1/783-872----------------------------------------------------------GRLGADLRY.DAE---------
D3Q8U1_STANL/765-853----------------------------------------------------------GYLGADFTV.D..---------
Q8ZXG0_PYRAE/721-807----------------------------------------------------------GGLGAEFKW.D..---------
E8WXR8_ACISM/803-890----------------------------------------------------------GLLGADYTI.V..---------
D2AWH2_STRRD/739-825----------------------------------------------------------GKLGVDWSF.E..---------
Q020G3_SOLUE/804-893----------------------------------------------------------GLLGADYEI.V..---------
B0VF46_CLOAI/747-837----------------------------------------------------------GKLGIDYRY.NAR---------
A9BIW8_PETMO/751-841----------------------------------------------------------GYLGADLIL.D..---------
B3QU45_CHLT3/747-837----------------------------------------------------------GLLGADISY.STE---------
D9QMJ3_BRESC/796-884----------------------------------------------------------GLLGADYAI.Q..---------
C6WJJ9_ACTMD/754-843----------------------------------------------------------GLLGADLERGE..---------
E4NAZ7_KITSK/757-844----------------------------------------------------------GLLGADLVR.D..---------
C7Q5E5_CATAD/793-881----------------------------------------------------------GLLGADLAP.D..---------
E4RW77_LEAB4/768-855----------------------------------------------------------GYLGIDWQA.D..---------
C1N9P1_MICPC/828-915----------------------------------------------------------GRLGCDLVW.D..---------
D2ARY8_STRRD/732-815----------------------------------------------------------GLLGADLSW.N.G---------
B5GPX5_STRC2/828-913----------------------------------------------------------GMLGADLVR.R..---------
B5HKU3_9ACTO/746-831----------------------------------------------------------GLLGANFVL.R..---------
E4NBJ1_KITSK/740-825----------------------------------------------------------GLLGANAHR.A.P---------
A6KZI1_BACV8/751-841----------------------------------------------------------GLLGAELSR.D..---------
A6LFH5_PARD8/757-847----------------------------------------------------------GLLGAEVSR.D..---------
F3Z9P9_9ACTO/761-850----------------------------------------------------------GLLGADISR.H.E---------
F3ZGH8_9ACTO/873-959----------------------------------------------------------GLLGADFTC.R..---------
TRI_SULSO/773-858----------------------------------------------------------GGLGAEFEY.DES---------
Q5LCE8_BACFN/758-848----------------------------------------------------------GLLGAEITR.D..---------
V4IJ74_9ACTO/752-841----------------------------------------------------------GLLGADLAR.D.E---------
V4J1V6_9ACTO/791-877----------------------------------------------------------GLLGANLVR.V..---------

PF00595

DVL1_MOUSE/251-336TVTLNME..RH-----------------------------------------------HFLGISIVG-QSN---DR....
ZO1_MOUSE/23-107TVTLHRA..PG-----------------------------------------------FGFGIAISG-GRD---NPHF..
ZO1_MOUSE/186-261KVTLVKS.RKN-----------------------------------------------EEYGLRLAS-...---......
ZO1_MOUSE/423-501KLVKFR...KG-----------------------------------------------DSVGLRLAG-GND---V.....
AFAD_HUMAN/1009-1090TVTLKK....Q-----------------------------------------------NGMGLSIVA-AKG---AGQ...
PTN3_HUMAN/510-595LIRITPD..ED-----------------------------------------------GKFGFNLKG-GVD---QK....
SP4B_BACSU/103-184DLKVIP...GG-----------------------------------------------QSIGVKLHS-VGV---LV....
CTPA_SYNP2/102-182SLKVSTS.GEL-----------------------------------------------SGVGLQINV-NPE---V.....
PDLI1_RAT/5-82QIVLQ....GP-----------------------------------------------GPWGFRLVG-GKD---FE....
APBA1_HUMAN/656-740DVFIEKQ..KG-----------------------------------------------EILGVVIVE-SGW---GS....
APBA2_MOUSE/660-733TVLIKRP.DLK-----------------------------------------------YQLGFSVQ.-...---......
DLG1_DROME/216-300DIQLER...GN-----------------------------------------------SGLGFSIAG-GTD---NPHI..
DLG1_DROME/330-418EIDLVK...GG-----------------------------------------------KGLGFSIAG-GIG---NQHI..
DLG1_DROME/506-584TITIQK...GP-----------------------------------------------QGLGFNIVG-GED---G.....
PDLI4_HUMAN/4-81SVTLR....GP-----------------------------------------------SPWGFRLVG-GRD---FS....
DSH_DROME/252-337TVSINME..AV-----------------------------------------------NFLGISIVG-QSN---RG....
EM55_TAKRU/73-151EVAFEKN..QS-----------------------------------------------EPLGVTLKL-NDK---Q.....
EM55_HUMAN/71-149LIQFEKV..TE-----------------------------------------------EPMGITLKL-NEK---Q.....
DEGQ_ECOLI/257-346QLIDFGE.IKR-----------------------------------------------GLLGIKGTE-MSA---DIAKAF
DEGQ_ECOLI/365-444SASAEMI..TP-----------------------------------------------ALEGATLSD-GQL---KD....
DEGS_ECOLI/248-336LIRDGRV..IR-----------------------------------------------GYIGIGGRE-IAP---LHAQGG
DEGS_HAEIN/242-322KIMRDGR.VIR-----------------------------------------------GYFGVQSDI-SSS---SE....
HTOA_HAEIN/268-358QQILEFGQVRR-----------------------------------------------GLLGIKGGE-LNA---DLAKAF
HTOA_HAEIN/377-455QLSSKTE..LP-----------------------------------------------ALDGATLKD-YDA---KG....
DEGPL_BARHE/289-378QQLIEKGLVQR-----------------------------------------------GWLGVQIQP-VTK---EISDSI
DEGP_ECOLI/279-368QMVEYGQ.VKR-----------------------------------------------GELGIMGTE-LNS---ELAKAM
DEGP_SALTY/386-464QSQVDS...ST-----------------------------------------------IFSGIEGAE-MSN---KG....
LIMK1_HUMAN/165-255LVSIPAS..SH-----------------------------------------------GKRGLSVSI-DPP---HGPPGC
LIMK2_CHICK/152-236LISMPAA..TD-----------------------------------------------GKRGFSVSV-EGG---CSS...
LIMK2_RAT/152-236LISMPAT..TE-----------------------------------------------CRRGFSVSV-ESA---SSN...
LIN2_CAEEL/546-624LVQFQKD..TQ-----------------------------------------------EPMGITLKV-NED---G.....
NOS1_HUMAN/17-96SVRLFKR..KV-----------------------------------------------GGLGFLVKE-RVS---K.....
PRC_HAEIN/244-328SFNESIN.LSL-----------------------------------------------EGIGTTLQS-EDD---......
DLG4_RAT/65-149EITLER...GN-----------------------------------------------SGLGFSIAG-GTD---NPHI..
DLG4_RAT/160-244EIKLIK...GP-----------------------------------------------KGLGFSIAG-GVG---NQHI..
DLG4_RAT/313-391RIVIHR...GS-----------------------------------------------TGLGFNIVG-GED---G.....
PTN4_HUMAN/516-602VLIRMKP.DEN-----------------------------------------------GRFGFNVKG-GYD---QK....
PTP1_CAEEL/616-703VTIKMRP.DRH-----------------------------------------------GRFGFNVKG-GAD---QN....
SIPA1_MOUSE/682-754ELALPRD..GQ-----------------------------------------------GRLGFEVDA-...---......
RSEP_ECOLI/203-277EPDKED...PV-----------------------------------------------SSLGIRPRG-PQI---......
PSMD9_YEAST/99-191RSHVLL...NQ-----------------------------------------------HFDNMNVKS-NQD---ARRNND
NM111_YEAST/290-375QWLLKPY.DEC-----------------------------------------------RRLGLTSER-ESE---ARAK..
YQI7_CAEEL/25-114EVIDAHG.QVT-----------------------------------------------IRVGFKIGG-GID---QDPTKA
PRC_ECOLI/238-320NTEMSL...SL-----------------------------------------------EGIGAVLQM-DDD---......

PF13180

C9A6A9_ENTCA/322-419----------------------------------------------------------PALGIQTID-LGSITSQQQEQI
Q7VJB0_HELHP/178-253----------------------------------------------------------GDLGIRFEN-SKA.........
A7ZFX4_CAMC1/179-256----------------------------------------------------------GDIGVKFLQ-KED.........
Q0S4Y2_RHOSR/404-487----------------------------------------------------------AVIGIQVPS-QDA.........
D1BL26_VEIPT/269-359----------------------------------------------------------PYIGVWAVD-RQTAARN.....
B1VP64_STRGG/452-541----------------------------------------------------------PVIGATVTM-EEK.........
D2R087_PIRSD/256-349----------------------------------------------------------GFLGVAPSL-LTPDER......
Q30TR4_SULDN/163-240----------------------------------------------------------GDIGIRVKD-ENS.........
A0RM44_CAMFF/175-252----------------------------------------------------------GDIGVTFSD-DNG.........
C9ZC44_STRSW/506-595----------------------------------------------------------PVIGASVSL-EEG.........
B1XQ68_SYNP2/485-563----------------------------------------------------------PYLGLTVTD-QNN.........
A9B2Z4_HERA2/473-551----------------------------------------------------------PQLGIRSKA-VDG.........
Q315Q4_DESAG/369-449----------------------------------------------------------SRMGFTLVM-AEG.........
D5SYB3_PLAL2/269-351----------------------------------------------------------GLMGISFTG-NDL.........
Q1D977_MYXXD/477-552----------------------------------------------------------GWLGVTTRG-SGT.........
C8X5D5_DESRD/676-755----------------------------------------------------------PVLGLQVRS-QDG.........
B2IZX7_NOSP7/201-295----------------------------------------------------------GYLGVGMQP-VRLPKNLKT...
B5HUE3_9ACTO/403-492----------------------------------------------------------AKIGASVSL-EDS.........
D2QHW4_SPILD/97-182----------------------------------------------------------NGIGALIGQ-RQ..........
A2TY74_9FLAO/100-182----------------------------------------------------------VGIGVQFRM-IKD.........
F3Z8A9_9ACTO/527-616----------------------------------------------------------PVIGATVSL-EEG.........
G2SPM5_LACRR/328-425----------------------------------------------------------PALGISLVD-LDYVSEADRSQT
O24877_HELPY/170-247----------------------------------------------------------GDIGVRLEE-HHK.........
Q0P7Y5_CAMJE/170-244----------------------------------------------------------GDIGVDFVV-REN.........
Q5HNH7_STAEQ/304-394----------------------------------------------------------PSIGIGLIN-LSDIPENYR...
Q79HP3_WOLSU/168-242----------------------------------------------------------.DLLIRFEK-NRR.........
Q8DMW2_STRR6/293-388----------------------------------------------------------PALGIQMVN-LSNVSTSDIR.R
Q8Y5K8_LISMO/122-196----------------------------------------------------------....QEVKV-TYD.........
Q99XG9_STRP1/301-396----------------------------------------------------------PALGISMVN-LNDLSTNALS.Q
Q9HSH6_HALSA/244-350----------------------------------------------------------AYLGVSFTP-VTPTVADA....
R5FHL8_9CLOT/166-248----------------------------------------------------------.GIGAMLSQ-NRT.........
R5KJ64_9CLOT/126-209----------------------------------------------------------AGIGVVVRQ-DED.........

PF12812

NM111_ASHGO/373-450AITPSR---YV-----------------------------------------------EVCGATFNE-LSY---------
B8MUN1_TALSN/264-341AITPDR---FV-----------------------------------------------SVAGATFHD-LSY---------
NM111_PICST/379-456SITPDR---YV-----------------------------------------------DVGGASFNN-LSY---------
NM111_PICGU/388-465SITPSR---YV-----------------------------------------------DIAGASFND-LSY---------
NM111_LODEL/379-456AITPDR---FV-----------------------------------------------HVAGASFNN-LSY---------
C5MEA8_CANTT/370-447DITPNR---FV-----------------------------------------------SVAGATFND-MSY---------
NM111_CANGA/374-451AITPSK---YV-----------------------------------------------EVCGATFNE-LSY---------
NM111_KLULA/388-465IITPSR---YV-----------------------------------------------EVCGANFHE-LSY---------
C4R214_PICPG/366-443AITPAR---YL-----------------------------------------------EVCGASFND-LSY---------
NM111_YARLI/360-439SITPDR---YV-----------------------------------------------EVCGASFQD-LSY---------
B6JWG1_SCHJY/372-448AIAPDR---YV-----------------------------------------------EVCGATFHN-LSY---------
B2WNT3_PYRTR/845-923DLETDR---LV-----------------------------------------------SFCGATFHR-.PH---------
C4Y709_CLAL4/134-212SMNTSR---VV-----------------------------------------------FWCGALLQE-.PH---------
NM111_KLULA/861-937ETT..R---IV-----------------------------------------------VFAGCVLQA-.PH---------
Q6CHS4_YARLI/371-442ALSCTE---FV-----------------------------------------------KFGGMTFHN-MTY---------
B6QC43_PENMQ/337-413AIVPTR---IL-----------------------------------------------NDSGASFHN-VPY---------
A9RQ61_PHYPA/347-422SITPNM---FL-----------------------------------------------EVSGGVLHA-LSY---------
A8JH35_CHLRE/368-444TVTPNC---FL-----------------------------------------------ELAGGAVHA-LSY---------
C1EGI7_MICSR/349-424DVTPSR---FL-----------------------------------------------EVCGGVVHA-LSY---------
C1N456_MICPC/359-434AITPSR---ML-----------------------------------------------EIAGGVVNA-LSY---------
YH05_SCHPO/393-469NVTPSR---FL-----------------------------------------------EVGGAVLHD-LSY---------
B8FNF0_DESAA/337-420KIT..R---FA-----------------------------------------------TFAGGTFHP-LTP---------
NM111_MAGO7/393-469SITPDR---FV-----------------------------------------------SVAGGSFHS-LSY---------
B2ASP9_PODAN/396-472KITPDR---FV-----------------------------------------------SVAGGSFHE-LSY---------
B2WNT3_PYRTR/372-451AITPDK---FV-----------------------------------------------SVAGASFHD-LSY---------
C0NX23_AJECG/394-470EITPAR---YV-----------------------------------------------TVAGATFHD-LSY---------
B6HPJ1_PENCW/491-567DITPDR---FV-----------------------------------------------TVAGASFHD-LSY---------
B6K3R7_SCHJY/399-475SVTPSR---FL-----------------------------------------------EVGGTIFHD-LSY---------
NM111_YEAST/392-469AITPHR---YV-----------------------------------------------EVCGATFHE-LSY---------
Q5A946_CANAL/376-453SITPNR---FV-----------------------------------------------VVAGASFND-LSY---------
Q6ZIR2_ORYSJ/179-252SITPNH---FL-----------------------------------------------EVSGAVIHP-LSY---------
Q7MWL5_PORGI/399-469.ITGES---TG-----------------------------------------------NVLGASFKD-LSA---------

PF04495

Q2LYW0_DROPS/69-205----EGANESVWHILEVH.PN--------SPAELAG.LRA-------------YSDYVIGA--D..........AIR---
Q0U7P0_PHANO/83-216----A.LAEDVWHILDVA.PN--------SPADVAG.LLP-------------YGDYVIGS--PE.........GLV---
Q6BX19_DEBHA/130-306----N.TATYVWRILNTH.HN--------SPAFQAQ.LIP-------------YSDYIIGC--DSAYPQDAEGKGLL---
A5DBW3_PICGU/154-329----N.TATYVWRILQTH.MG--------SPAFQAQ.LVP-------------YSDYIIGC--DSASPDEPQGQGLL---
GORS2_MOUSE/69-205----DGANENVWHVLEVE.SN--------SPAALAG.LRP-------------HSDYIIGA--D..........TVM---
Q0IEU2_AEDAE/69-205----EGANENVWHILEVH.PS--------SPAEEAG.LIP-------------FTDYIIGA--D..........SIL---
Q5KDT5_CRYNJ/68-205----AHALESVYHVLDVL.EG--------SPAEMAG.LVP-------------WGDYVLAW--SG.........GPL---
YAT2_SCHPO/80-213----APAVDAIWHILNVI.DD--------SPVARAS.LVP-------------YEDYIVGT--PE.........GMM---
GORS1_MOUSE/68-204----RRASEHVWHVLDVE.PS--------SPAALAG.LCP-------------YTDYIVGS--D..........QIL---
Q4UCI6_THEAN/70-205----S.CLDEGAHIVHVY.DK--------SPAQKAG.LMP-------------ITDYLLGT--NL.........QLF---
Q54C46_DICDI/73-210----EKTLENVWHVLDVY.LN--------SPAHEAE.LQT-------------RLDYIVGT--PD.........LIL---
Q2UN33_ASPOR/80-214----S.STQHIWHVLNIPSPL--------SPAYRAG.LLP-------------HSDYIIGT--PS.........GTL---
A7ARE9_BABBO/70-205----T.AMDEGAHVINVH.DG--------SPAKKAG.LMP-------------ITDYLLGT--NL.........QLF---
Q4Q3U9_LEIMA/103-265----DACPERCVHVVDVL.EG--------SPAACSTELQA-------------NRDYIIGM--QTVQE...TLITLI---
Q22G20_TETTS/89-227----LNSHDNTFKVVTVD.EN--------SPAKIAG.LQA-------------KQDYIIGL--KK.........YKY---
Q386P4_TRYB2/73-244----EKCVERCWHVVDVI.PG--------SPVAKCGEIKE-------------GRDYIIGI--QKADE...LVTALI---
Q4PFN7_USTMA/83-237----SQALSHVWHILEIL.EG--------SPAESAG.LVP-------------FGDFVIGW--PG.........GVL---
Q2HFQ7_CHAGB/78-211----A.VVSNIWHVLDVP.AN--------SPADAAG.LLP-------------YSDYILGT--PE.........GVL---
B0S774_DANRE/70-205----QGANENVWHVLDVE.SN--------SPAALAG.LQE-------------HSDFIVGA--D..........QVL---
E7KBH0_YEASA/142-281----I.ASTFTYHILNVNIPD--------GPAQSAG.LIP-------------DEDYIIGC--QD.........GLL---

PF14685

TRIC_SULTO/556-640----N..KC..YKIARIY-VGDPTNENERSPLRDPGVQLN-------------IGDCIKAV--DG---------EEV---
TRI_THEAC/763-849----G..DH..YVVAKAY-AGDYSNEGEKSPIFEYGIDP.-------------TGYLIEDI--DG---------ETV---
Q4J6J4_SULAC/709-795----EQREC..FKIVKIY-SGDPTNEGERSPLKDPGVELN-------------EGDCIYSI--DG---------EKV---
A5US97_ROSS1/783-872----T..DS..YVVERVI-RGDVWDERASSPLAQPGINIV-------------PGDRLIAV--GG---------HRV---
D3Q8U1_STANL/765-853----T.DGA..HTIAKIY-TGDPWKPDATSSLLRPGVDAR-------------VGDTVVAV--NG---------QPV---
Q8ZXG0_PYRAE/721-807----G..KC..WRIAKIF-VGDPSYENEKSPLLAPGVDVR-------------EGDCIISI--AG---------VRL---
E8WXR8_ACISM/803-890----N..NQ..YCIAKLY-DGGHWNPNMTGPLTQPGLNVH-------------VGDCITAI--GG---------KPL---
D2AWH2_STRRD/739-825----D..GL..YRVARIV-NGDRWDPEVTSPLNRLGVDVR-------------PGDVVLAV--NG---------QPV---
Q020G3_SOLUE/804-893----N..GR..YRFKKIY-AGESWNPQVQSPLTQPGLNVN-------------EGDYLLAV--NG---------QEL---
B0VF46_CLOAI/747-837----K..KG..YEIIRIL-KGDYWLSENRSPFMNPGLNVS-------------EGWIIKAV--NG---------IPV---
A9BIW8_PETMO/751-841----E..DRKLYKISHIV-KGDIWDEKNKPPLLGPGVEVK-------------EGDYLLAI--NG---------IEI---
B3QU45_CHLT3/747-837----K..KA..FEVTGLP-KGDFWKEGEASPLHTPGVNVQ-------------VGDLILEV--NG---------QSL---
D9QMJ3_BRESC/796-884----G..GR..WCITKIY-GPTAFSPDVTGPLAQPGVDAR-------------VGDCVLSV--DD---------RAV---
C6WJJ9_ACTMD/754-843----D..GS..WRIARVI-PGETSDPAARSPLSAPGVAVR-------------AGDVITAV--DG---------RQV---
E4NAZ7_KITSK/757-844----G..EV..WRVARVL-PGESSDPRARSPLAAPGAAVR-------------PGDALLAV--NG---------RPV---
C7Q5E5_CATAD/793-881----E.DGV..WRIVKIL-PGDNSVPAARSPLLAPGIAAR-------------VGDAITAV--DG---------LPV---
E4RW77_LEAB4/768-855----G..NH..YKVGKII-RGASWDAEVRSPLEKSGIK..-------------EGSYILEV--NG---------LPI---
C1N9P1_MICPC/828-915----A..KMRGYRITHIV-GGDQWDDLTGGALRKPGLNVA-------------VGDAIVAL--NR---------VTL---
D2ARY8_STRRD/732-815----D..GR..WQVDRVL-PGESSDVHARSPLAVPGAGIQ-------------QGETLLAV--DG---------RPV---
B5GPX5_STRC2/828-913----D..GR..WVVRRIL-PGESSDSKARSPLAGTGIP..-------------EGAVITHV--DG---------RPV---
B5HKU3_9ACTO/746-831----E..GG..WTVRRIL-PGDSSDSKARSPLAGTGIR..-------------EGAVLTHV--DG---------RPV---
E4NBJ1_KITSK/740-825----D..GR..WLVDRIL-PGESSDPKARAPLAGHGLR..-------------DGDELLAV--DG---------RPP---
A6KZI1_BACV8/751-841----K.SGF..YRIDKIL-PGAIYSQKLRSPLTEPGIGVK-------------EGDYITAI--DG---------IST---
A6LFH5_PARD8/757-847----K.SGF..FRLEKIL-PGASWSKELRSPLTEPGVEAK-------------AGEYIVAI--DG---------VPT---
F3Z9P9_9ACTO/761-850----D..GQ..WHVDRVL-PSETSDPHARSPLAGPGIAVR-------------AGDTLLAV--GG---------RPV---
F3ZGH8_9ACTO/873-959----D..GA..WELRRIL-PGESSDPRARSPLAGTGIR..-------------EGAVLTHV--DG---------RPV---
TRI_SULSO/773-858----N..KC..YKITKIY-VGDSTNENERSPLRDPGVQLN-------------VGDCIKNI--DG---------ED.---
Q5LCE8_BACFN/758-848----K.SGF..FRLEKIF-PGASWSKELRSPLTEPGVDVK-------------VGEYIVAI--DG---------VPT---
V4IJ74_9ACTO/752-841----E..GV..WRVERVL-PSETSDPHAHSPLAAPGVAVR-------------AGDAILAV--DG---------QPV---
V4J1V6_9ACTO/791-877----G..DQ..WMLRRIL-PGDSSDTKARSPLAGTGIR..-------------EGAALTHV--DG---------RPV---

PF00595

DVL1_MOUSE/251-336......GDGGIYIGS--------IMKG..GAVAADGRIEP--------------GDMLLQV..ND.....----VNF---
ZO1_MOUSE/23-107....QSGETSIVISD--------VLKG..GPAEGQ..LQE--------------NDRVAMV..NG.....----VSM---
ZO1_MOUSE/186-261.........HIFVKE--------ISQD..SLAARDGNIQE--------------GDVVLKI..NG.....----TVT---
ZO1_MOUSE/423-501.........GIFVAG--------VLED..SPAAKEG.LEE--------------GDQILRV..NN.....----VDF---
AFAD_HUMAN/1009-1090......DKLGIYVKS--------VVKG..GAADVDGRLAA--------------GDQLLSV..DG.....----RSL---
PTN3_HUMAN/510-595........MPLVVSR--------INPE.SPADTCIPKLNE--------------GDQIVLI..NG.....----RDI---
SP4B_BACSU/103-184........VGFHQIN--------TSEGKKSPGETAG.IEA--------------GDIIIEM..NG.....----QKI---
CTPA_SYNP2/102-182........DVLEVIL--------PLPG..SPAEAAG.IEA--------------KDQILAI..DG.....----IDT---
PDLI1_RAT/5-82........QPLAISR--------VTPG.SKAAIAN..LCI--------------GDLITAI..DG.....----EDT---
APBA1_HUMAN/656-740......ILPTVIIAN--------MMHG..GPAEKSGKLNI--------------GDQIMSI..NG.....----TSL---
APBA2_MOUSE/660-733.........NGIICS--------LMRG..GIAERGG.VRV--------------GHRIIEI..NG.....----QSV---
DLG1_DROME/216-300.....GTDTSIYITK--------LISG..GAAAADGRLSI--------------NDIIVSV..ND.....----VSV---
DLG1_DROME/330-418.....PGDNGIYVTK--------LMDG..GAAQVDGRLSI--------------GDKLIAVRTNGS...E----KNL---
DLG1_DROME/506-584........QGIYVSF--------ILAG..GPADLGSELKR--------------GDQLLSV..NN.....----VNL---
PDLI4_HUMAN/4-81........APLTISR--------VHAG.SKAALAA..LCP--------------GDLIQAI..NG.....----EST---
DSH_DROME/252-337......GDGGIYVGS--------IMKG..GAVALDGRIEP--------------GDMILQV..ND.....----VNF---
EM55_TAKRU/73-151.........RCSVAR--------ILHG..GMIHRQGSLHE--------------GDEIAEI..NG.....----KSV---
EM55_HUMAN/71-149.........SCTVAR--------ILHG..GMIHRQGSLHV--------------GDEILEI..NG.....----TNV---
DEGQ_ECOLI/257-346...NLDVQRGAFVSE--------VLPG.SGSAKAG..VKA--------------GDIITSL..NG.....----KPL---
DEGQ_ECOLI/365-444......GGKGIKIDE--------VVKG.SPAAQAG..LQK--------------DDVIIGV..NR.....----DRV---
DEGS_ECOLI/248-336...GIDQLQGIVVNE--------VSPD.GPAANAG..IQV--------------NDLIISV..DN....K----PAI---
DEGS_HAEIN/242-322........EGIVITD--------VSPN.SPAAKSG..IQV--------------GDVILKL..NN.....----QEG---
HTOA_HAEIN/268-358...NVSAQQGAFVSE--------VLPK..SAAEKAG.LKA--------------GDIITAM..NG.....----QKI---
HTOA_HAEIN/377-455.......VKGIEITK--------IQPN.SLAAQRG..LKS--------------GDIIIGI..NR.....----QMI---
DEGPL_BARHE/289-378...GLKEAKGALITD--------PLKG..PAAKAG..IKA--------------GDVIISV..NG.....----EKI---
DEGP_ECOLI/279-368...KVDAQRGAFVSQ--------VLPN.SSAAKAG..IKA--------------GDVITSL..NG.....----KPI---
DEGP_SALTY/386-464......QDKGVVVSS--------VKAN.SPAAQIG..LKK--------------GDVIIGA..NQ.....----QPV---
LIMK1_HUMAN/165-255...GTEHSHTVRVQG--------VDPG.CMSPDVKNSIHV--------------GDRILEI..NG.....----TPI---
LIMK2_CHICK/152-236......YATGVQVKE--------VNRM.HISPDVRNAIHP--------------ADRILEI..NG.....----API---
LIMK2_RAT/152-236......YATTVQVKE--------VNRM.HISPNNRNAIHP--------------GDRILEI..NG.....----TPV---
LIN2_CAEEL/546-624.........RCFVAR--------IMHG..GMIHRQATLHV--------------GDEIREI..NG.....----MSV---
NOS1_HUMAN/17-96........PPVIISD--------LIRG..GAAEQSGLIQA--------------GDIILAV..NG.....----RPL---
PRC_HAEIN/244-328.........EISIKS--------LVPG..APAERSKKLHP--------------GDKIIGV..GQATGDI----EDV---
DLG4_RAT/65-149.....GDDPSIFITK--------IIPG..GAAAQDGRLRV--------------NDSILFV..NE.....----VDV---
DLG4_RAT/160-244.....PGDNSIYVTK--------IIEG..GAAHKDGRLQI--------------GDKILAV..NS.....----VGL---
DLG4_RAT/313-391........EGIFISF--------ILAG..GPADLSGELRK--------------GDQILSV..NG.....----VDL---
PTN4_HUMAN/516-602........MPVIVSR--------VAPG.TPADLCVPRLNE--------------GDQVVLI..NG.....----RDI---
PTP1_CAEEL/616-703........YPVIVSR--------VAPG.SSADKCQPRLNE--------------GDQVLFI..DG.....----RDV---
SIPA1_MOUSE/682-754.........EGFITH--------VERF..TFAETTG.LRP--------------GARLLRV..CG.....----QTL---
RSEP_ECOLI/203-277.........EPVLEN--------VQPN..SAASKAG.LQA--------------GDRIVKV..DG.....----QPL---
PSMD9_YEAST/99-191DQAIQYTIPFAFISE--------VVPG.SPSDKAD..IKV--------------DDKLISI..GN.....----VHA---
NM111_YEAST/290-375....FPENIGLLVAE--------TVLR.EGPGYDK..IKE--------------GDTLISI..NG.....----ETI---
YQI7_CAEEL/25-114..PFKYPDSGVYITN--------VESG..SPADVAG.LRK--------------HDKILQV..NG.....----ADF---
PRC_ECOLI/238-320.........YTVINS--------MVAG..GPAAKSKAISV--------------GDKIVGV..GQTGKPM----VDV---

PF13180

C9A6A9_ENTCA/322-419LKVPSSVTSGVVIYS........VNNA--TPAEQAG.LQQ..............YDVITKI--DD---------TEV...
Q7VJB0_HELHP/178-253.........I.............VKSI--DPFVPQNPFKP..............QDKILSI--NG---------AKV...
A7ZFX4_CAMC1/179-256.........KFF...........VGLV--DPLGRGKMMMV..............DDELVTI--NG---------IKP...
Q0S4Y2_RHOSR/404-487.......ANGATVVE........VTAG--SPAEKAG.IPK..............GSVITKV--DD---------RVI...
D1BL26_VEIPT/269-359..NVSYEGEGLLIVQ........LDST--GPAAQAG.LVE..............GDTIAQI--DG---------KDI...
B1VP64_STRGG/452-541.......TGGAAISAEGAGGTPAVTPN--GPAAKAG.LKA..............GDVITKF--ND---------TVI...
D2R087_PIRSD/256-349....RAGKLGARIAD........VVPA--TPAAKAG.LAM..............GDIVTHV--GE---------VPV...
Q30TR4_SULDN/163-240.........VVI...........VKES--NPFVESNQLKV..............GDVILEF--DT---------RKV...
A0RM44_CAMFF/175-252.........TIT...........VKSA--NPFGAGKELLT..............GDTIVSV--NS---------KVP...
C9ZC44_STRSW/506-595.......TGGAKITNSGGGGSESITAN--GPADKAG.LKP..............GDVITKL--DD---------HVI...
B1XQ68_SYNP2/485-563.........RTLVQT........VNVD--SPAHQAG.IDP..............EDELLAI--TN---------YRT...
A9B2Z4_HERA2/473-551.........RVQITH........VLDG--GDADRAG.LAA..............GDELIAL--DG---------WRI...
Q315Q4_DESAG/369-449.........RVTVQD........VAED--SPARRAG.FRA..............GDVLRSA--DG---------AQV...
D5SYB3_PLAL2/269-351.......SGDAPVVE.......RVRFQ--SPAAAAG.ILV..............NDVIVAA--DN---------IPI...
Q1D977_MYXXD/477-552............VAV........VMDG--SPAQDAG.LYV..............EDDLVAL--NG---------WKV...
C8X5D5_DESRD/676-755.........GVVVQN........IHDG--TPAVASG.LRT..............GDHILRF--QD---------RAE...
B2IZX7_NOSP7/201-295.ALNLTSATGVIVVN........VESS--GPADNAG.VLL..............GDILVTF--DG---------VTV...
B5HUE3_9ACTO/403-492.......SGGAKITTEGAGGSAPVESG--GPAAKAG.LKP..............GDVITKL--DD---------HVI...
D2QHW4_SPILD/97-182.........GKSIVL.......MVYEG--TPAEKSG.LQI..............GDEVLKV--DG---------VDL...
A2TY74_9FLAO/100-182.........SITVIQ........PIKG--GPSIKAG.IKA..............GDRILMA--NS---------DTLFGK
F3Z8A9_9ACTO/527-616.......MDGATVSDQGAGSDPAVTPG--GPAAKAG.LKS..............GDTITKF--DD---------TII...
G2SPM5_LACRR/328-425LNLPSKVTSGVVVIK........VNSS--SPLKKTD.ISK..............YDVIVSL--GG---------KKV...
O24877_HELPY/170-247.........RLV...........VVQF--DPFFPKNPFLK..............NDEILAI--NH---------QKI...
Q0P7Y5_CAMJE/170-244.........KIYVNN........VRKN--.P....Q.FLI..............NDQVISV--DG---------LPA...
Q5HNH7_STAEQ/304-394KELHTHKDKGVYVAK........VDSE--NA......IKK..............GDIITGI--DG---------KQI...
Q79HP3_WOLSU/168-242.........EPV...........VALI--DPFIEENLFRL..............GDRVLSL--EG---------RAI...
Q8DMW2_STRR6/293-388LNIPSNVTSGVIVRS........VQSN--MPANGH..LEK..............YDVITKV--DD---------KEI...
Q8Y5K8_LISMO/122-196.........GVYVLS........VKDD--VPAADV..LHA..............GDLITEI--DG---------NAF...
Q99XG9_STRP1/301-396INIPTSVTGGIVVAE........VKEG--MPASGK..LAQ..............YDVITEI--DG---------KTV...
Q9HSH6_HALSA/244-350..NGLTESRGLLVMS........VDPS--GPSAGRL.VGSDATTIVDGGAVRVGGDIVLAV--NG---------TRV...
R5FHL8_9CLOT/166-248.......TGLCTIVK........VFEG--SPALEAG.MQP..............GDIIYKV--GD---------TLVA.S
R5KJ64_9CLOT/126-209.......TGYAIAVS........ITED--SPASEAD.IKP..............DDLICKI--DD---------YEI...

PF12812

NM111_ASHGO/373-450------QMARYYAIP--------VR..AVFLSSATGSFCF......DTK..EKLGWIVDEV--NN---------QPT---
B8MUN1_TALSN/264-341------QQARLYAIA--------CR..GVYVCEAAGSFKI......DDN..TPSGWIIDSV--GR---------QPT---
NM111_PICST/379-456------QVARCYCIP--------VK..GVFINDASGSFEF......ASY..EKSGWLLETV--DD---------MPT---
NM111_PICGU/388-465------QVARCFCIP--------VR..GVFINDGSGSFEL......SPF..EKNGWLLEYV--DD---------KPT---
NM111_LODEL/379-456------QVARCYCLP--------VR..GLYVCDGSGSFEF......SNQ..DTLGFIVETV--DD---------KPV---
C5MEA8_CANTT/370-447------QIARSFGLP--------VK..GVFVNHGAGSFEF......SSQ..DTLGWFIQAV--DD---------VPV---
NM111_CANGA/374-451------QMARFYALP--------IR..GVFLSSASGSFNF......DNK..EKIGWIVDSV--NY---------QDT---
NM111_KLULA/388-465------QMARCYALP--------VK..GVFVASATGSFDL......DPK..EKTGWVIDFV--DN---------KET---
C4R214_PICPG/366-443------QMARLYAIP--------VR..GVFANRASGSFTL......DTR..DRCGWIIDSL--DH---------KDT---
NM111_YARLI/360-439------QLARIYAIP--------VR..GVYVSEVGGSFRL......DGQGNESKGWVVDSI--DD---------IDT---
B6JWG1_SCHJY/372-448------QLARQYALP--------VR..RVFISEPTGSFYL......EG...SDYGYLLESI--AH---------KPV---
B2WNT3_PYRTR/845-923------QAVRQQISK--------IHSDVYISSRARGSPAY......MYG..LAPTNFVTHV--NN---------VPT---
C4Y709_CLAL4/134-212------QSVRQLMEK--------IPSEVYVARKSAGGPMT......QYG..ISNSVFITHV--ND---------QET---
NM111_KLULA/861-937------HAVRQVKTS--------IPSEVYAVSRGTSSLAL......QYG..IEVTNFITHV--ND---------QST---
Q6CHS4_YARLI/371-442------QLVRSTNEP--------ID..GVIVACGGPTD.............VNCRSKLYKI--NG---------KKI---
B6QC43_PENMQ/337-413------RTAVCWKVP--------LK..GMFLASSAINFSL......GD...ESNSYIISSI--NN---------HPT---
A9RQ61_PHYPA/347-422------QQARNLHFV--------CG..IVYVAEPGYMLSC......AG...VPRHAIIKKM--AG---------EEI---
A8JH35_CHLRE/368-444------QQARNNRAV--------VG..QVYVAEPGYMLGR......AN...VPKCAIITGL--NG---------KPT---
C1EGI7_MICSR/349-424------QQARNFQLP--------VG..SVYVAEPGYVLGL......AG...LSKHAIITSL--NN---------VPT---
C1N456_MICPC/359-434------QQARNFQLP--------CG..GVYVAEPGYVLGV......AN...VPKHAILTSL--GN---------TPT---
YH05_SCHPO/393-469------QLARSYQFS--------LN.SGTYVA.SSGMLNW......SS...GTRDFLVTRL--AN---------KPT---
B8FNF0_DESAA/337-420------EIRLDLDIA--------SD..GVYLSQAELGSTFGSVGYSSSRNPDRKGVVVQGI--NG---------QPV---
NM111_MAGO7/393-469------QQARLYGVA--------CK..GVYVCEATGSFRF.......ET..SDNGWILQTI--DN---------KKV---
B2ASP9_PODAN/396-472------QQARLYGVA--------CK..GVYVCEAGGSWRF.......ES..SECGWLIQTV--DH---------KKT---
B2WNT3_PYRTR/372-451------QQARLYAIS--------LKGAGVYVCEAAGSFRF......ADG..YTSGWLIQEV--DN---------QPT---
C0NX23_AJECG/394-470------QQARLYAIA--------CK..GVYVCEAAGSFKL.......EN..TFSGWIVDTV--DK---------RPT---
B6HPJ1_PENCW/491-567------QQSRLYAIA--------TR..GVYVCESAGSFKL.......EN..TVAGWIIDSI--DK---------RPV---
B6K3R7_SCHJY/399-475------QLARSYQCA--------FN.SGTFVA.ASGMLNW......SG...GTRDFLVTKL--AN---------IPT---
NM111_YEAST/392-469------QMARFYALP--------VR..GVFLSSASGSFNF......DSK..ERVGWIVDSI--DN---------KET---
Q5A946_CANAL/376-453------QIARCYGLP--------VK..GVFVNGGTGSFEF......SPQ..DTLGWMIESV--DD---------ERV---
Q6ZIR2_ORYSJ/179-252------QQARNFRFK--------CG..LVYVAEAGYMLSR......AS...VPRHAIIKKL--AG---------EDI---
Q7MWL5_PORGI/399-469------EQMRSYGVS--------YG..VEVTSVSSGKFKD......AG...IKKGFIILSI--NR---------QPV---

PF04495

Q2LYW0_DROPS/69-205H..EN-DDLF------TLID--THEQ--Q.............................PLKMYVYNLDDD--ACREVTIK
Q0U7P0_PHANO/83-216R..GE-SGLG------ELVE--DFLN--R.............................PLRLIVYNHEYD--VTRPVTIT
Q6BX19_DEBHA/130-306AKGGE-SLLS------RTVM--SYYN--LHYSAS...................QEDNVPITLYVYNHDYD--ILRPVTVN
A5DBW3_PICGU/154-329TSGGE-ALLS------RVVL--NYYN--QHYSKT...................NDDFVPITLYVYNHDYD--ILRPVTVN
GORS2_MOUSE/69-205N..ES-EDLF------SLIE--THEA--K.............................PLKLYVYNTDTD--NCREVIIT
Q0IEU2_AEDAE/69-205H..ES-EDLF------TLIE--SHKG--R.............................PLKMYVYNIDRD--ACREVTIT
Q5KDT5_CRYNJ/68-205H..SE-NDFY------NLIE--AHVD--K.............................PLRLFVYNADLD--NLREVVLY
YAT2_SCHPO/80-213T..GE-KALS------DLIE--SHLN--R.............................PLRLYIYNHYRD--STRQVTIV
GORS1_MOUSE/68-204Q..ES-EDFF------TLIE--SHEG--K.............................PLKLMVYNSESD--SCREVTVT
Q4UCI6_THEAN/70-205Y..DL-DCVR------IHVA--NKVD--K.............................EVVLIVYNSVTE--TVRRALIV
Q54C46_DICDI/73-210N..EQ-EDFF------TLIN--NNMY--R.............................PIQLYVYSSLTE--QIRLVTIT
Q2UN33_ASPOR/80-214R..GE-SALG------ELVE--DHLD--R.............................TLVLWVYNSEFD--VVREVELV
A7ARE9_BABBO/70-205V..DS-DCVR------VHVG--ERVD--E.............................DVTLYVYNSVTE--TIRKTVIT
Q4Q3U9_LEIMA/103-265K..SQ-KDFY------CRLE--AWHE--EQRWALERKQF.........FPNERVEVPHVLLFLVYNSESN--TIEEVEV.
Q22G20_TETTS/89-227E..GL-DELI------NIIF--DNEG--Q.............................EIELVVFNISDK--SVRSVMLK
Q386P4_TRYB2/73-244K..DE-DDLY------TRVE--LWRT--AQSAALRRLQRNSFVPTGASREDRGLQTAGQLLLLVYDSVNI--EVKEVLV.
Q4PFN7_USTMA/83-237Q..AE-GDFY------ELVE--AHTD--R.............................ALRLYVYNSDYD--HTREVIIV
Q2HFQ7_CHAGB/78-211H..GE-GGLS------ELVE--DHIG--R.............................PLRLYVYNNEYN--VTREVTIQ
B0S774_DANRE/70-205Q..DS-EDFF------SLIE--AHEG--K.............................PLKLLIYNTETD--KCREVIVT
E7KBH0_YEASA/142-281ATGGE-TLLQ------DIVR--SRAN--Y.............................DLVLYVYNKVSD--CVRPITV.

PF14685

TRIC_SULTO/556-640K--..-YNIL------SYLV--NKDQ...-----------------------------.VVLDVITK.G...KTKRVTV-
TRI_THEAC/763-849G--AG-SNIY------RVLS--EKAG..T-----------------------------SARIRLSGK.GG..DKRDLMI-
Q4J6J4_SULAC/709-795R--K.-GSIN------SHFI--NKDQ...-----------------------------.AILEVLTS.DG..KNRTVSV-
A5US97_ROSS1/783-872G--RN-VSPH------ELLI--NQAG..S-----------------------------DVLLTFMKM.DG..TLRSVTV-
D3Q8U1_STANL/765-853G--PT-TSVA------QLLV--NQAD..Q-----------------------------EVRLSLRRG.EA..DPHVVVV-
Q8ZXG0_PYRAE/721-807G--PN-APPE------YALL--NRTS..D-----------------------------VVTVEVER..GG..EVKAFTV-
E8WXR8_ACISM/803-890T--AA-EDIQ------RPLE--GTAG..H-----------------------------AVTLRLATG.SA..PARDITI-
D2AWH2_STRRD/739-825G--PS-AGPD------ERLV--NQAD..Q-----------------------------EVQLTVRR..GQ..DKRTFNV-
Q020G3_SOLUE/804-893Q--GT-EDVS------RLLE--NTSG..K-----------------------------HVLLKIASD.AAGANAREITV-
B0VF46_CLOAI/747-837T--KT-IPPE------RLTL--NLAG..Q-----------------------------QVQLTVSSP.DN.KEEKVVTI-
A9BIW8_PETMO/751-841K--DK-.IPN------EFLV--NYSG..K-----------------------------DVEIVVSSS.DNIDHKRKYVV-
B3QU45_CHLT3/747-837S--KN-QSFG------ELLV--SMAG..Q-----------------------------EITLTVANA.KK.ENMRRVRI-
D9QMJ3_BRESC/796-884S--AD-MDIQ------SALE--GTAG..R-----------------------------MVTLRLGAS.SG.ANGRDVTV-
C6WJJ9_ACTMD/754-843D--PL-TGPA------PLLV--GTAG..K-----------------------------PVELVVRPGGDG..DPRRVVV-
E4NAZ7_KITSK/757-844D--PV-TGPA------PLLA--GTAD..H-----------------------------PVELTVRGA.DG..AERHPVV-
C7Q5E5_CATAD/793-881P--PR-VGPA------ALLA--GKAD..Q-----------------------------PTELVLQTQ.SG..KRTVVVV-
E4RW77_LEAB4/768-855S--TN-KDPY------YYFA--GLNN..V-----------------------------AVELTYNDK.PSLEGAKRAIV-
C1N9P1_MICPC/828-915T--EE-VGVD------EVLT--GKGG..A-----------------------------EVMVTFKRG.D....VVSVRV-
D2ARY8_STRRD/732-815P--PQ-.GPA------SLLV--GAAD..K-----------------------------AVELTLGG.......GRRVVV-
B5GPX5_STRC2/828-913D--PV-AGPF------PMLA--GAGG..T-----------------------------TVELTFRTD.DG..GARRVAV-
B5HKU3_9ACTO/746-831D--EL-AGPS------PLLA--AAGG..T-----------------------------TVELTFTPA.EG..EGRSRRV-
E4NBJ1_KITSK/740-825D--PV-RGPA------PLLA--GTGG..S-----------------------------TVELTVRH..EN..RIRRIAV-
A6KZI1_BACV8/751-841A--TV-DNIY------SLLA--GKAN..V-----------------------------LTELSINRT.ASSKGVRKVVI-
A6LFH5_PARD8/757-847N--SV-NDMY------KLLI--GKAN..V-----------------------------PTELSLNSK.PQLAGARKIVV-
F3Z9P9_9ACTO/761-850D--PL-LGPG------PLLA--GTAG..H-----------------------------VTELTIGPA.DG.GEPRHVVV-
F3ZGH8_9ACTO/873-959D--PV-TGPA------PLLA--GAAG..T-----------------------------SVELTFAST.TG.GPPRRVAV-
TRI_SULSO/773-858.--AN-GNIY------SHLI--NKDQ...-----------------------------.VILDVITA.DG..KNKRVTV-
Q5LCE8_BACFN/758-848N--TV-KDMY------SLLV--GKAEIPT-----------------------------EISLNVKPQ.LS..GARKVVI-
V4IJ74_9ACTO/752-841D--PV-TGPG------PLLV--GTAG..K-----------------------------PVELTVSPA.GG.GDPRHTVV-
V4J1V6_9ACTO/791-877D--PV-TGPY------PLLA--GAGG..T-----------------------------TVELTFRAA.EG.GRSRRVAV-

PF00595

DVL1_MOUSE/251-336E--NM.SNDD------AVRV--LREI--VSQ..TG-----------------------PISLTVA---------------
ZO1_MOUSE/23-107D--NV.EHAF------AVQQ--LRKS--GK.....-----------------------NAKITIR---------------
ZO1_MOUSE/186-261E--NM.SLTD------AKTL--IERS--KG.....-----------------------KLKMVVQ---------------
ZO1_MOUSE/423-501T--NI.IREE------AVLF--LLDL--PKG...E-----------------------EVTILAQ---------------
AFAD_HUMAN/1009-1090V--GL.SQER------AAEL--MTRT--SS.....-----------------------VVTLEVA---------------
PTN3_HUMAN/510-595S--EH.THDQ------VVMF--IKAS--RESH.SR-----------------------ELALVIR---------------
SP4B_BACSU/103-184E--KM.NDVA------PFIQ--KAGK--TG....E-----------------------SLDLLIK---------------
CTPA_SYNP2/102-182R--NI.GLEE------AAAR--MRGK--KG....S-----------------------TVSLTVK---------------
PDLI1_RAT/5-82S--SM.THLE------AQNK--IKGC--VD.....-----------------------NMTLTVS---------------
APBA1_HUMAN/656-740V--GL.PLST------CQSI--IKGL--KNQ...S-----------------------RVKLNIV---------------
APBA2_MOUSE/660-733V--AT.AHEK------IVQA--LSNS--VG.....-----------------------EIHMKTM---------------
DLG1_DROME/216-300V--DV.PHAS------AVDA--LKKA--GN.....-----------------------VVKLHVK---------------
DLG1_DROME/330-418E--NV.THEL------AVAT--LKSI--TD.....-----------------------KVTLIIG---------------
DLG1_DROME/506-584T--HA.THEE------AAQA--LKTS--GG.....-----------------------VVTLLAQ---------------
PDLI4_HUMAN/4-81E--LM.THLE------AQNR--IKGC--HD.....-----------------------HLTLSVS---------------
DSH_DROME/252-337E--NM.TNDE------AVRV--LREV--VQK..PG-----------------------PIKLVVA---------------
EM55_TAKRU/73-151A--NQ.TVDQ------LQKI--LKET--NG.....-----------------------VVTMKII---------------
EM55_HUMAN/71-149T--NH.SVDQ------LQKA--MKET--KG.....-----------------------MISLKVI---------------
DEGQ_ECOLI/257-346N--SF.AELR------SRIA--TTEP--GT.....-----------------------KVKLGLL---------------
DEGQ_ECOLI/365-444N--SI.AEMR------KVLA--AKPA--.......-----------------------IIALQIV---------------
DEGS_ECOLI/248-336S--AL.ETMD------QVAE--IRPG--S......-----------------------VIPVVVM---------------
DEGS_HAEIN/242-322I--SA.REMM------QIIA--NTKP--NS.....-----------------------KVLVTIL---------------
HTOA_HAEIN/268-358S--SF.AEIR------AKIA--TTGA--GK.....-----------------------EISLTYL---------------
HTOA_HAEIN/377-455E--NI.RELN------KVLE--TEPS--.......-----------------------AVALNIL---------------
DEGPL_BARHE/289-378N--DV.RDLA------KRIA--NMSP--GE.....-----------------------TVTLGVW---------------
DEGP_ECOLI/279-368S--SF.AALR------AQVG--TMPV--GS.....-----------------------KLTLGLL---------------
DEGP_SALTY/386-464K--NI.AELR------KILD--SKPS--.......-----------------------VLALNIQ---------------
LIMK1_HUMAN/165-255R--NV.PLDE------IDLL--IQET--SR.....-----------------------LLQLTLE---------------
LIMK2_CHICK/152-236R--TL.QVEE------VEDL--IRKT--SQ.....-----------------------TLQLLIE---------------
LIMK2_RAT/152-236R--TL.RVEE------VEDA--INQT--SQ.....-----------------------TLQLLIE---------------
LIN2_CAEEL/546-624A--NR.SVES------LQEM--LRDA--RG.....-----------------------QVTFKII---------------
NOS1_HUMAN/17-96V--DL.SYDS------ALEV--LRGI--AS.....-----------------------ETHVVLI---------------
PRC_HAEIN/244-328V--GW.RLED------LVEK--IKGK--KG....T-----------------------KVRLEIE---------------
DLG4_RAT/65-149R--EV.THSA------AVEA--LKEA--GS.....-----------------------IVRLYVM---------------
DLG4_RAT/160-244E--DV.MHED------AVAA--LKNT--YD.....-----------------------VVYLKVA---------------
DLG4_RAT/313-391R--NA.SHEQ------AAIA--LKNA--GQ.....-----------------------TVTIIAQ---------------
PTN4_HUMAN/516-602A--EH.THDQ------VVLF--IKAS--CERH.SG-----------------------ELMLLVR---------------
PTP1_CAEEL/616-703S--TM.SHDH------VVQF--IRSA--RSGLNGG-----------------------ELHLTIR---------------
SIPA1_MOUSE/682-754P--KL.GPET------AAQM--LRSA--P......-----------------------KVCVTVL---------------
RSEP_ECOLI/203-277T--QW..VTF------VMLV--RDNP--GK.....-----------------------SLALEIE---------------
PSMD9_YEAST/99-191A--NH.SKLQ------NIQM--VVMK--NED...R-----------------------PLPVLLL---------------
NM111_YEAST/290-375S--SFMQVDK------IQDE--NVGK--.......-----------------------EIQLVIQ---------------
YQI7_CAEEL/25-114T--MM.THDR------AVKF--IKQS--K......-----------------------VLHMLVA---------------
PRC_ECOLI/238-320I--GW.RLDD------VVAL--IKGP--KG....S-----------------------KVRLEIL---------------

PF13180

C9A6A9_ENTCA/322-419S--TT-TDLQ......SALY..KHKV--GD----------------------------TITVTFYR......GDEEKTAE
Q7VJB0_HELHP/178-253Q--TS-DEAE......WVMS..NLKK--DS----------------------------LAQVTLLR......NGKTLNLK
A7ZFX4_CAMC1/179-256K--SL-RELN......EMVL..FAPK--GA----------------------------RLDIIVKR......DREQLLFQ
Q0S4Y2_RHOSR/404-487T--SG-DALI......AAIR..SHAP--GD----------------------------NVSITYTDG....NGSNTKTVD
D1BL26_VEIPT/269-359T--TL-LELK......ERID..AKSP--GD----------------------------TVLVSYTH......NGKMKSTQ
B1VP64_STRGG/452-541D--SG-PTLI......GEIW..TRKP--GE----------------------------KVTLTYER......DGKEATAE
D2R087_PIRSD/256-349I--DD-LHLI......RLLS..GMFA--GS----------------------------EVTLTVERGSSTLLNARKLDLE
Q30TR4_SULDN/163-240K--DS-ASFM......RNIL..FSSI--GS----------------------------THNVKIKR......DNKIVTLR
A0RM44_CAMFF/175-252N--NL-REIN......EMIL..FAPK--DA----------------------------VLKFDINR......DGKNQSYS
C9ZC44_STRSW/506-595D--SG-PTLI......GEIW..THRP--GD----------------------------KVTLTYTR......DGKTRTAD
B1XQ68_SYNP2/485-563.--NA-EQLN......HRLQ..NYQA--GD----------------------------TISITIFH......QDQLKTLA
A9B2Z4_HERA2/473-551.--DE-DGLN......KRLA..DYPI--GA----------------------------TVQLSFFR......RDELLHVP
Q315Q4_DESAG/369-449N--SL-WDMH......KAGM.QAARE--KR----------------------------PVVFGVQR......DGAMLSLE
D5SYB3_PLAL2/269-351A--RL-GNLK......HVLG..RKYA--GD----------------------------QLQLKILR......KKDPLEVT
Q1D977_MYXXD/477-552.--DG-ATLL......SRCE..ERRP--GE----------------------------TVRLTVFR......RDRLLEIP
C8X5D5_DESRD/676-755T--DV-ASLV......EAVR..ACTP--GQ----------------------------RVNLQVRR......GDTLQTVS
B2IZX7_NOSP7/201-295G--DT-GDVL......ALLN.SSDRI--GK----------------------------TVNLQVIR......GGVLIELA
B5HUE3_9ACTO/403-492D--SG-PTLI......GEIW..THKP--GD----------------------------KVKITYER......DGQTHTVD
D2QHW4_SPILD/97-182K--TR-KDRDGGPLDPGKLL..KGQN--NT----------------------------AVKLTVSR......YGQKAPLE
A2TY74_9FLAO/100-182N--LR-TGSV......PKYL..KGKP--NT----------------------------DVSLQVYR......KSNDSLFN
F3Z8A9_9ACTO/527-616D--SG-PTLI......GEIW..THQP--GD----------------------------KVKITYKR......DGSEHTTE
G2SPM5_LACRR/328-425S--GL-SSLR......TALY..GHKV--GD----------------------------TVEIQYYH......KGELKKAN
O24877_HELPY/170-247H--SL-AEFE......WVVS..NLKY--QS----------------------------LAKVEIKR......NHKVKEVT
Q0P7Y5_CAMJE/170-244N--DL-RKLN......EKIL..FADR--GS----------------------------TLYFQVLR......DNMDLNIS
Q5HNH7_STAEQ/304-394K--DD-TDLR......TYLY.ESKKP--GE----------------------------TVTLKVIR......DGKTQDIN
Q79HP3_WOLSU/168-242G--SR-SELE......NQIY..GLAP--GR----------------------------EVRVSVMR......EGEVVSFE
Q8DMW2_STRR6/293-388A--SS-TDLQ......SALY..NHSI--GD----------------------------TIKITYYR......NGKEETTS
Q8Y5K8_LISMO/122-196K--SS-QEFI......DYIH..SKKV--GD----------------------------TVKINYKH......GDKNEQAD
Q99XG9_STRP1/301-396N--SI-SDLQ......SSLY..GHDI--ND----------------------------TIKVTFYR......GTTKKKAD
Q9HSH6_HALSA/244-350H--TL-EDVL......SLLA.LHTSP--GD----------------------------TVSVRLLR......DGDRRTVD
R5FHL8_9CLOT/166-248E--SL-DVLV......NNYI..KGEE--GT----------------------------DVAITVYR......ADKDEYVD
R5KJ64_9CLOT/126-209Q--ES-DDLD......YLVTKIRGEE--GT----------------------------DVTLEIYR......PSERKYYT

PF12812

NM111_ASHGO/373-450P--TL-DTFI------EVMS--------------------------------------TIPDC-----------------
B8MUN1_TALSN/264-341R--NL-QEFI------QVMK--------------------------------------TIPDR-----------------
NM111_PICST/379-456P--DL-DTLI------EVMK--------------------------------------MIPDC-----------------
NM111_PICGU/388-465P--NL-DAFV------EVMK--------------------------------------SIPDR-----------------
NM111_LODEL/379-456A--NL-DEFV------EVMK--------------------------------------QLPDC-----------------
C5MEA8_CANTT/370-447G--NL-DEFV------EAMK--------------------------------------NVPDK-----------------
NM111_CANGA/374-451P--NL-DAFV------EVMK--------------------------------------TIPDK-----------------
NM111_KLULA/388-465P--TL-DDFI------EVMK--------------------------------------TIPDE-----------------
C4R214_PICPG/366-443P--DL-DTFI------EVLK--------------------------------------SIPDC-----------------
NM111_YARLI/360-439P--DL-DTFI------KVIA--------------------------------------AIPDG-----------------
B6JWG1_SCHJY/372-448P--DL-DAFI------EVMK--------------------------------------TLPDR-----------------
B2WNT3_PYRTR/845-923P--NL-SAFL------TEIK--------------------------------------KIKDN-----------------
C4Y709_CLAL4/134-212P--DL-ETFV------KITN--------------------------------------DIPDN-----------------
NM111_KLULA/861-937P--DL-DTFL------KVVK--------------------------------------EIPDN-----------------
Q6CHS4_YARLI/371-442S--NL-TELK------EFFK--------------------------------------NA.VH-----------------
B6QC43_PENMQ/337-413R--NV-IEGE------KVLS--------------------------------------KLKDR-----------------
A9RQ61_PHYPA/347-422D--NL-DKFI------SVFF--------------------------------------KL.SR-----------------
A8JH35_CHLRE/368-444P--DL-ITFA------TVLR--------------------------------------TLPHG-----------------
C1EGI7_MICSR/349-424P--DL-DAFA------NAYA--------------------------------------RL.EE-----------------
C1N456_MICPC/359-434P--DL-DAFA------AAYA--------------------------------------KL.KE-----------------
YH05_SCHPO/393-469P--TL-DAFI------DVLV--------------------------------------QLTDN-----------------
B8FNF0_DESAA/337-420R--NL-DDFI------RLAS--------------------------------------ALKHN-----------------
NM111_MAGO7/393-469P--DL-ETFI------QVVK--------------------------------------NIPDK-----------------
B2ASP9_PODAN/396-472P--DL-DTFI------DVLK--------------------------------------GIPDK-----------------
B2WNT3_PYRTR/372-451P--DL-DTFI------QVMK--------------------------------------KIPDR-----------------
C0NX23_AJECG/394-470K--NL-DEFI------EVVK--------------------------------------TIPDR-----------------
B6HPJ1_PENCW/491-567R--NL-NEFV------EVMK--------------------------------------NIPDR-----------------
B6K3R7_SCHJY/399-475P--NL-EALT------KVIL--------------------------------------GLRDN-----------------
NM111_YEAST/392-469P--DL-DTFI------EIMK--------------------------------------TIPDR-----------------
Q5A946_CANAL/376-453E--DL-DEFV------EVMK--------------------------------------KIPDC-----------------
Q6ZIR2_ORYSJ/179-252E--NL-GDLI------ACIS--------------------------------------KL...-----------------
Q7MWL5_PORGI/399-469S--SG-ADVS------DIVR--------------------------------------.....-----------------

PF04495

Q2LYW0_DROPS/69-205PNTAWGGE...GALGCGIGFGYLHRIPVQ
Q0U7P0_PHANO/83-216PSRGWGGE...GALGCVLGFGALHRIPPS
Q6BX19_DEBHA/130-306LSRSWGTGQNRGILGCDVGYGLLHRIPEV
A5DBW3_PICGU/154-329LSRSWGTGHNKGVLGCDVGYGLLHRIPEV
GORS2_MOUSE/69-205PNSAWGGE...GSLGCGIGYGYLHRIPTR
Q0IEU2_AEDAE/69-205PNDKWGGE...GSLGCGIGYGYLHRIPIR
Q5KDT5_CRYNJ/68-205PTRQWGGE...GLIGCGIGYGLLHRIPRP
YAT2_SCHPO/80-213PNRHWGGN...GAIGCGVGHGVLHRLPAP
GORS1_MOUSE/68-204PNAAWGGE...GSLGCGIGYGYLHRIPTQ
Q4UCI6_THEAN/70-205PRENWGGR...GTLGCDLAKGYIHRIPYV
Q54C46_DICDI/73-210PNKNWGGS...GSLGCDIGFGLLHRIPTK
Q2UN33_ASPOR/80-214PTRGWGGE...GALGAELGYGALHRLPVG
A7ARE9_BABBO/70-205PRHGWGGS...GTLGCDLANGYIHRIPLV
Q4Q3U9_LEIMA/103-265...EMGTNP.EAAVGISVATGLLHIIPSV
Q22G20_TETTS/89-227PQMNWGGR...GLIGCEFGGGYLNQLPVI
Q386P4_TRYB2/73-244...DFGNDI.YAPLGMNLATGLLHLIPSP
Q4PFN7_USTMA/83-237PNREWGGE...GLLGCGVGYGLLHRIPKP
Q2HFQ7_CHAGB/78-211PSRDWGGE...GALGCVLGYGALHRLPAP
B0S774_DANRE/70-205PNGAWGGE...GSLGCGIGYGYLHRIPA.
E7KBH0_YEASA/142-281...HIGPD...GRLGCNVGYGFLHRIPT.

PF14685

TRIC_SULTO/556-640-----------------------------
TRI_THEAC/763-849-----------------------------
Q4J6J4_SULAC/709-795-----------------------------
A5US97_ROSS1/783-872-----------------------------
D3Q8U1_STANL/765-853-----------------------------
Q8ZXG0_PYRAE/721-807-----------------------------
E8WXR8_ACISM/803-890-----------------------------
D2AWH2_STRRD/739-825-----------------------------
Q020G3_SOLUE/804-893-----------------------------
B0VF46_CLOAI/747-837-----------------------------
A9BIW8_PETMO/751-841-----------------------------
B3QU45_CHLT3/747-837-----------------------------
D9QMJ3_BRESC/796-884-----------------------------
C6WJJ9_ACTMD/754-843-----------------------------
E4NAZ7_KITSK/757-844-----------------------------
C7Q5E5_CATAD/793-881-----------------------------
E4RW77_LEAB4/768-855-----------------------------
C1N9P1_MICPC/828-915-----------------------------
D2ARY8_STRRD/732-815-----------------------------
B5GPX5_STRC2/828-913-----------------------------
B5HKU3_9ACTO/746-831-----------------------------
E4NBJ1_KITSK/740-825-----------------------------
A6KZI1_BACV8/751-841-----------------------------
A6LFH5_PARD8/757-847-----------------------------
F3Z9P9_9ACTO/761-850-----------------------------
F3ZGH8_9ACTO/873-959-----------------------------
TRI_SULSO/773-858-----------------------------
Q5LCE8_BACFN/758-848-----------------------------
V4IJ74_9ACTO/752-841-----------------------------
V4J1V6_9ACTO/791-877-----------------------------

PF00595

DVL1_MOUSE/251-336-----------------------------
ZO1_MOUSE/23-107-----------------------------
ZO1_MOUSE/186-261-----------------------------
ZO1_MOUSE/423-501-----------------------------
AFAD_HUMAN/1009-1090-----------------------------
PTN3_HUMAN/510-595-----------------------------
SP4B_BACSU/103-184-----------------------------
CTPA_SYNP2/102-182-----------------------------
PDLI1_RAT/5-82-----------------------------
APBA1_HUMAN/656-740-----------------------------
APBA2_MOUSE/660-733-----------------------------
DLG1_DROME/216-300-----------------------------
DLG1_DROME/330-418-----------------------------
DLG1_DROME/506-584-----------------------------
PDLI4_HUMAN/4-81-----------------------------
DSH_DROME/252-337-----------------------------
EM55_TAKRU/73-151-----------------------------
EM55_HUMAN/71-149-----------------------------
DEGQ_ECOLI/257-346-----------------------------
DEGQ_ECOLI/365-444-----------------------------
DEGS_ECOLI/248-336-----------------------------
DEGS_HAEIN/242-322-----------------------------
HTOA_HAEIN/268-358-----------------------------
HTOA_HAEIN/377-455-----------------------------
DEGPL_BARHE/289-378-----------------------------
DEGP_ECOLI/279-368-----------------------------
DEGP_SALTY/386-464-----------------------------
LIMK1_HUMAN/165-255-----------------------------
LIMK2_CHICK/152-236-----------------------------
LIMK2_RAT/152-236-----------------------------
LIN2_CAEEL/546-624-----------------------------
NOS1_HUMAN/17-96-----------------------------
PRC_HAEIN/244-328-----------------------------
DLG4_RAT/65-149-----------------------------
DLG4_RAT/160-244-----------------------------
DLG4_RAT/313-391-----------------------------
PTN4_HUMAN/516-602-----------------------------
PTP1_CAEEL/616-703-----------------------------
SIPA1_MOUSE/682-754-----------------------------
RSEP_ECOLI/203-277-----------------------------
PSMD9_YEAST/99-191-----------------------------
NM111_YEAST/290-375-----------------------------
YQI7_CAEEL/25-114-----------------------------
PRC_ECOLI/238-320-----------------------------

PF13180

C9A6A9_ENTCA/322-419VKL--------------------------
Q7VJB0_HELHP/178-253VKV--------------------------
A7ZFX4_CAMC1/179-256VPV--------------------------
Q0S4Y2_RHOSR/404-487VTL--------------------------
D1BL26_VEIPT/269-359IKL--------------------------
B1VP64_STRGG/452-541VTL--------------------------
D2R087_PIRSD/256-349VLL--------------------------
Q30TR4_SULDN/163-240AIT--------------------------
A0RM44_CAMFF/175-252IKM--------------------------
C9ZC44_STRSW/506-595VTL--------------------------
B1XQ68_SYNP2/485-563VTL--------------------------
A9B2Z4_HERA2/473-551VTF--------------------------
Q315Q4_DESAG/369-449LSV--------------------------
D5SYB3_PLAL2/269-351IPL--------------------------
Q1D977_MYXXD/477-552VVL--------------------------
C8X5D5_DESRD/676-755LDT--------------------------
B2IZX7_NOSP7/201-295IAV--------------------------
B5HUE3_9ACTO/403-492LTL--------------------------
D2QHW4_SPILD/97-182LSV--------------------------
A2TY74_9FLAO/100-182VNI--------------------------
F3Z8A9_9ACTO/527-616VTL--------------------------
G2SPM5_LACRR/328-425VKL--------------------------
O24877_HELPY/170-247LKV--------------------------
Q0P7Y5_CAMJE/170-244TEV--------------------------
Q5HNH7_STAEQ/304-394VKL--------------------------
Q79HP3_WOLSU/168-242T..--------------------------
Q8DMW2_STRR6/293-388IKL--------------------------
Q8Y5K8_LISMO/122-196IKL--------------------------
Q99XG9_STRP1/301-396IKL--------------------------
Q9HSH6_HALSA/244-350VEL--------------------------
R5FHL8_9CLOT/166-248MSV--------------------------
R5KJ64_9CLOT/126-209VTL--------------------------

PF12812

NM111_ASHGO/373-450-----------------------------
B8MUN1_TALSN/264-341-----------------------------
NM111_PICST/379-456-----------------------------
NM111_PICGU/388-465-----------------------------
NM111_LODEL/379-456-----------------------------
C5MEA8_CANTT/370-447-----------------------------
NM111_CANGA/374-451-----------------------------
NM111_KLULA/388-465-----------------------------
C4R214_PICPG/366-443-----------------------------
NM111_YARLI/360-439-----------------------------
B6JWG1_SCHJY/372-448-----------------------------
B2WNT3_PYRTR/845-923-----------------------------
C4Y709_CLAL4/134-212-----------------------------
NM111_KLULA/861-937-----------------------------
Q6CHS4_YARLI/371-442-----------------------------
B6QC43_PENMQ/337-413-----------------------------
A9RQ61_PHYPA/347-422-----------------------------
A8JH35_CHLRE/368-444-----------------------------
C1EGI7_MICSR/349-424-----------------------------
C1N456_MICPC/359-434-----------------------------
YH05_SCHPO/393-469-----------------------------
B8FNF0_DESAA/337-420-----------------------------
NM111_MAGO7/393-469-----------------------------
B2ASP9_PODAN/396-472-----------------------------
B2WNT3_PYRTR/372-451-----------------------------
C0NX23_AJECG/394-470-----------------------------
B6HPJ1_PENCW/491-567-----------------------------
B6K3R7_SCHJY/399-475-----------------------------
NM111_YEAST/392-469-----------------------------
Q5A946_CANAL/376-453-----------------------------
Q6ZIR2_ORYSJ/179-252-----------------------------
Q7MWL5_PORGI/399-469-----------------------------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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