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4  structures 4158  species 0  interactions 12345  sequences 105  architectures

Clan: Peptidase_U (CL0472)


Peptidase clan U Add an annotation

This superfamily includes proteins classed as clan U by the MEROPS database. The proteins are membrane bound peptidases. The clan also includes Pfam:PF10086 which is a related family of uncharacterised proteins.

This clan contains 3 families and the total number of domains in the clan is 12345. The clan was built by A Bateman.


This clan contains the following 3 member families:

Abi DUF2324 PrsW-protease

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Abi (PF02517) 10595 (85.8%) View
PrsW-protease (PF13367) 1525 (12.4%) View
DUF2324 (PF10086) 225 (1.8%) View
Total: 3 Total: 12345 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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