Sequence alignment for CL0477

PF12950

B5ICQ9_ACIB4/763-920KPFLV-----------------GKD.IKRY--RIEFR..................DRY-----------LILIPSGWTNE
A0ZFG2_NODSP/1317-1435KSLLR-----------------GEN.IGRY--IFDYK..................GEY-----------VWYVPKIMTSH
C5CH49_KOSOT/887-1032KPYLT-----------------GKE.IKRY--SIEWK..................GKY-----------IILAKDGIDIP
Y3402_METJA/955-1077LPYLE-----------------G.N.VYRY--ETKLK.................LKNY-----------VDFSKHKNNEK
Q12U44_METBU/826-966KKFIE-----------------GKD.LSRY--SISDR..................GLY-----------LDYLPKMMYGP
B9DU79_STRU0/1021-1140RPYLD-----------------GEN.VSRY--KLTWN..................GEY-----------VKYG.ENLAAP
D0LRP5_HALO1/739-867YPLYF-----------------GRDELRPF--RLLWR..................GRY-----------LRRAAIPERNS
A4CM25_ROBBH/762-881VKEIK-----------------GKG.VHRY--SLNWT..................PSY-----------VKWGKWLMSPK
D6XZV1_BACIE/524-637EVVLK-----------------GKD.IYKY--NFVPG..................RNY-----------LEFLSNDFQQV
B5YJE4_THEYD/332-454LPLLN-----------------GRN.LKCN--EIIYE...................NL-----------TGYWIKKADIN
Q24XG1_DESHY/339-452EVIYR-----------------GSD.VYKY--RCLPG..................QNF-----------IRFEPKSFQQI
B0JLC9_MICAN/1017-1136KKLLD-----------------GRN.INKY--SISWD..................GFY-----------LDYDITKIHSC
B3QU01_CHLT3/277-390TPALT-----------------GRN.LSPG--KIDYE..................TNH-----------TNFWVKHSGAA
A5N0R0_CLOK5/377-495VEILK-----------------GEN.IKKF--QVLNN...................YY-----------YDFIPCNIKGG
A6GW88_FLAPJ/761-878LPLID-----------------GAE.INRY--ELSTP..................NKY-----------FNFISENIKSG
Q3IQE9_NATPD/931-1083HPILR-----------------GNE.IKKY--DIGIPDEHVIYTNGVQIDDYPQAKSY-----------LSEYREKLANR
C0R107_BRAHW/240-364KKLLK-----------------GKN.IKKY--KIEFD..................NNY-----------LIFERKKLNRA
B0VG24_CLOAI/333-455LPLLN-----------------GKN.LKCN--MINYN...................NL-----------TGYWVKKQDVN
A5I1A4_CLOBH/564-681.KIYK-----------------GKN.IKKF--.ICYS..................YFY-----------YDFKDENIKGG
C0R104_BRAHW/227-354KKVLF-----------------GKN.VHRY--SFEWT..................GFY-----------VNYDKSLIDKS
O25223_HELPY/388-501.PIFR-----------------GSD.ILKD--GLKAP..................SQF-----------INAGLKDCQQV
R6N9B4_9FIRM/545-657.MVLK-----------------GAD.ILKY--HINTT..................TNY-----------ITFEPENFQQV

PF01420

T1S1_METJA/225-407PEDWE.VFEIKDIFEV....KTGTT-PSTKKSEYWEN------------------GEI...........NWITPLDLSRL
O25209_HELPY/1-179MSEWQ.TFCLKDLGKI....VGGAT-PPTN..NPKNY------------------GNK..........ISWITPK.DLST
O25519_HELPY/109-276PKGVE.FRKLGEVCES...TNKKTL-KISEVSEVKNK------------------GMY...........PVINSGRDLYG
O27024_METTH/222-387PVDWD.VVNLEDVVEI...HDNKRI-PLSEKERIKMK------------------GDY...........PYCGAN.....
O27024_METTH/15-193PVDWG.VSRVSEVFDV....FTGTT-PSTKIDEFWDD------------------GDV...........VWVTPA.DMSN
T1S_SALTY/7-187PEGWA.TSTINEMCNL......NPK-LKLD..DDLDV------------------GFM...........PMAGVP.TTYL
T1S_SALTY/225-410PSLWK.ISEIGQFADV....KGGKR-LPKGESLIAEN------------------TGF...........PYIRAGQLKNG
T1SH_MYCPN/62-225NIPFE.TFQVKDICEI....RRGRA-ITKA.YIRNNP------------------GEN...........PVYSAA.TTND
T1SA_MYCPN/147-310KEENK.YYKLGEIAQKVLVGGEKPA-DFSK..EKNEV------------------YKY...........PILSNN.SKAE
Y1531_METJA/22-203PEDWE.VRELKDILEV....IRNGL-TAK...QNKDK------------------IGY...........PITRIETISDS
T1SH_METJA/22-201PKDWD.VKKIKDIGEV....AGGST-PSTK.IKEYWG------------------GDI...........PWITPK.DLAN
T1SB_MYCPN/179-342GEEYK.LFKLKDIAKKILVGGEKPS-DFQK..EKDQV------------------YKY...........PILSNS.RKAD
Q88AU8_PSESM/13-174YVTSV.DGRQAGVFHA....HKGRR-LIA...AHRKA------------------GTT...........PFVGAS.RVNN
Q1WR64_LACS1/1-159MVKFQ.KFRIGDLFTA....ESGDT-DLKK..VDIEN------------------NGV...........PVITSGVQNYG
Q88AU8_PSESM/192-354ELNYM.PMFITDVFESM..NAAGKW-FDFAKACLSGK------------------PFA...........PYIARSGGGNG
O25479_HELPY/241-404PKGVE.FRKLGEVCEI...LDNRRI-PIAK..NKRNP------------------GIY...........PYYGAN.....
T1SI_HAEIN/195-369IDEMNKVIELGDVGPV....RMCKR-ILKN..QTASS------------------GDI...........PFYKIG.TFGK
O25479_HELPY/13-194PKGVE.FKTLEEVFEI....KNGYT-PSKNNPEFWKN------------------GTI...........PWFRMEDIREN
Q1WR64_LACS1/216-380NGKKV.NVSNDGLFNI...MSTKKK-INAN..TITFG------------------GKY...........PYVARG.ENQN
T1SG_MYCPN/114-279NIPFE.TFQIRDICEI....NRGRE-INEK.YLRENP------------------GEF...........PVYSSA.TTNG
T1SI_HAEIN/16-176EVEWK...PLDEVANI...VNNARK-PVKS..SLRVS------------------GNI...........PYYGAN.....
T1S1_METJA/17-197PEDWE.IVELKDVCKK...IKAGGT-PKTSVEEYYKN------------------GTI...........PFVKIEDITNS
T1SX_MYCPN/10-171NSNWT.KKTLGSLFEL....KKGEM-LEKE..LLAPD------------------GKY...........EYFNGG.....
T1SH_HAEIN/1-179MSDWK.EYSLGDIS........RNI-SRRF..DFNAY------------------PNV...........VFINTGDVLNN
O28563_ARCFU/140-319PKEWE.VVRLGDVLEL........C-QYGLSVPLKDK------------------GKY...........PVIRMDEIVNG
Y1218_METJA/22-191PEDWE.VVRIGDFIKYI.KGKKPAV-MV....DEELE------------------GYY...........PYLSTE.YLRD
T1SH_HAEIN/266-440PRGWE.MKALSDLGQI....ICGKT-PSKS..NKEFY------------------GDD..........VPFIKIP.DMHN
Y1218_METJA/220-404PEDWE.VVKLKEVVDI....QSGKY-FKYS..EFCEN------------------GVKCLKIDNVGFGKIFWETVSFLPE
O26006_HELPY/204-368..TWQ.SFRLGDLFEI....EKTLS-FNKD..ALTQG------------------EDY...........DYITRT.SQNQ
Q1GA73_LACDA/197-372.DEWE.ERKLGDIAPL....RGGFA-FKSS..KFRNT------------------GV............PIVRISNILSS
Q9CHS0_LACLA/229-396.DDWE.ERKLGEVATF....LNGRA-YKQD..ELLDS------------------GKY...........KVLRVGNFYTN

PF12950

B5ICQ9_ACIB4/763-920HKKGRSAWEWFSSEYPAIAKHLAQFEEKAKKRWDKGEYWWELRPCDYYEEFEKPKIMF..P---------DIAL.RMQ..
A0ZFG2_NODSP/1317-1435R...........................RTAR.PGNKLRFE...........QPKVLI..R---------DTGN.GLM..
C5CH49_KOSOT/887-1032HDYPAIYE............HLSQYKEALEKRWDKGKYWYNLRPCAYYSEFEKPKIVW..G---------NLAK.TAS..
Y3402_METJA/955-1077L...................................INLFM..........SPEKIFI..R---------RIVN.RQDR.
Q12U44_METBU/826-966R...........................V.......PEFFE...........SPKLIT..R---------HVSG.KNDS.
B9DU79_STRU0/1021-1140R...........................D.......KEIFE...........KPRILV..R---------QIPS.KSTYA
D0LRP5_HALO1/739-867K...........................ARYAGAGQRAWHE...........TPKLLL..R---------RTGD.SVR..
A4CM25_ROBBH/762-881S...................................EHYYK...........QHKILL..R---------QITGEYFF..
D6XZV1_BACIE/524-637A...........................P.......ERFYR..........AKEKLIY..R---------FINK.KLV..
B5YJE4_THEYD/332-454K...........................L.......RGYFN...........IPHIVVGLG---------FRENGRVA..
Q24XG1_DESHY/339-452A...........................P.......IDLYR..........AKEKLIY..R---------FIGG.SLV..
B0JLC9_MICAN/1017-1136K...........................R.......RDIFE..........TKEKLLF..R---------RVSR.TLI..
B3QU01_CHLT3/277-390T...........................L.......REFYG...........FAHIVI..G---------HTKGARVV..
A5N0R0_CLOK5/377-495T...........................SD.....IKKLTT...........KNKIII..R---------KTGK.HLI..
A6GW88_FLAPJ/761-878G...........................D.......FSIYE...........RLRIVI..R---------QIGQ.TPI..
Q3IQE9_NATPD/931-1083S...........................DGA..FKGKEWFELNIPLSTEVLDSNKILC..P---------DISE.ENN..
C0R107_BRAHW/240-364R...........................P.......DEVWN..........SDKKIIT..Q---------RISG.GLHP.
B0VG24_CLOAI/333-455K...........................I.......RMYFG...........YPHIVVGLG---------FRENGKVA..
A5I1A4_CLOBH/564-681T...........................KD.....LKKLKY...........KGKILV..R---------KTGN.EII..
C0R104_BRAHW/227-354K...........................KEYGNLCEEKYFE...........NPKILL..R---------DISK.RPD..
O25223_HELPY/388-501A...........................P.......LSLYQ..........AREKIVY..K---------FISS.KLV..
R6N9B4_9FIRM/545-657A...........................P.......TEIYR..........AQEKLLY..R---------FISN.QFV..

PF01420

T1S1_METJA/225-407N--------------EKIYIGSSERKVTKIALEKCNLNLIP----------.KGSIIISTR........APVGY------
O25209_HELPY/1-179L--------------QGRYIKKGSRSISRLGFKSCSCVLLP----------.KHAILFSSR........APIGY------
O25519_HELPY/109-276.--------------..................YYHDFNND----------.GENITIASRG......E.YAGF------
O27024_METTH/222-387.--------------..............GIIDYINDYIFN----------.GEFVLLAEDGG....DYSSFGS------
O27024_METTH/15-193L--------------NGIMIADSERKVTVKALKRTNLNLIP----------.KLSILISTR........APVGY------
T1S_SALTY/7-187G--------------KC......NFETKKWSEVKKGFTQFQ----------.NDDVIFAKITPCFENGKAVVIK------
T1S_SALTY/225-410.--------------..........TVLPEGQLYLEEYIQK----------SISRYTVSSGDLYITIVGACIGD------
T1SH_MYCPN/62-225.--------------..............GELGRIKDCDFD----------.GEYITWTTN........GYAGV------
T1SA_MYCPN/147-310.--------------..............EFLVYSKTFRVE----------.EKSITVSAR........GTIGA------
Y1531_METJA/22-203K--------------I........DITKLGYVEDIKQEDIA----------.KYRLIIGDILFSHINSEEHIGK------
T1SH_METJA/22-201Y--------------EYIYISRGERNITEKAVKECSLRIFP----------.KGTILLTSR........APIGY------
T1SB_MYCPN/179-342.--------------..............DFLGYSKTFRIA----------.EKSITVSAR........GTIGA------
Q88AU8_PSESM/13-174.--------------..............SITGFADTPALF----------PGGWITLIYNG......DGGTGH------
Q1WR64_LACS1/1-159.--------------.............ILGLATRKAKVIP----------.KNTITVD...........MFGN------
Q88AU8_PSESM/192-354.--------------............VGSFVPHQGFAPPN----------AGNAITIGV..........STST------
O25479_HELPY/241-404.--------------..............GIQDYIDSYIFD----------.GDFVLVG...........EDGS------
T1SI_HAEIN/195-369K--------------PD......AYISNELFQEYKQKYSYP----------KKGDILISAS........GTIGR------
O25479_HELPY/13-194G--------------RIL....KDSIQHITPKALKGKKLFP----------.KNSIIISTK........ATIGE------
Q1WR64_LACS1/216-380.--------------...........GIRGYINFDENYLNP----------.EKTISFGQ..........DTAT------
T1SG_MYCPN/114-279.--------------..............GLIGKINDYDFH----------.GEYVTWTTG.......GAHAGN------
T1SI_HAEIN/16-176.--------------..............NIQDYVEGYTHE----------.GEFVLIAED........GSASL------
T1S1_METJA/17-197N--------------KYLT..NTKIKITEEGLNNSNAWIVP----------.KNSVLFAMY........GSIGE------
T1SX_MYCPN/10-171.--------------.............IKASGRTNEFNTF----------.KNTISIIIG........GSCGY------
T1SH_HAEIN/1-179K--------------FLH....CEISNVKDLPGQAKKAIKK----------.GDILYSEIR........PGNGR------
O28563_ARCFU/140-319Y--------------VVT....DIAKYADLDEETFKNFKLE----------.KGDVLFNRTNSL..ELVGRTGI------
Y1218_METJA/22-191G--------------..........IASKFVKITNKEIIVN----------.ENDILLLWD.......GSNAGE------
T1SH_HAEIN/266-440Q--------------VFIT..QTTDNLSVVGANYQSKKYIP----------.AKSICVSCI........ATVGL------
Y1218_METJA/220-404.--------------..............DYLNKYPQLVLK----------.SGDIVLALNRPIIGGKI.KIGI------
O26006_HELPY/204-368.--------------...........GVLQTTGFVNAENL.----------.NPPFTWSLG........LLQMD------
Q1GA73_LACDA/197-372G--------------EV.....GGDFAYYDEQDKDDKYILP----------DKSAVLAMSG........ATTGK------
Q9CHS0_LACLA/229-396D--------------..........SWYYSNMELGDKYYVD----------.KGDLVYTWS........ATFGP------

PF12950

B5ICQ9_ACIB4/763-920..ATYDDK----A-----F--YCVNTAYIIP.......................VGDKYLL-------------------
A0ZFG2_NODSP/1317-1435..GTYEEL----N-----F--YVK.DVLIISHQQKCT.................KTLKILV-------------------
C5CH49_KOSOT/887-1032..FAYDNF----G-----K--YVNAPACIMP.......................TSEIWLL-------------------
Y3402_METJA/955-1077IMASYGNI----E-----G--VVKKDLYVFVLKPDTP.................INYFYLL-------------------
Q12U44_METBU/826-966LIFTIDKM----G-----Y--YSDHGLIMSTDYENLNSKNRTSFSDYTVDSKHNYQIELLL-------------------
B9DU79_STRU0/1021-1140VEAVYTDS----D-----V--IN..DLNSMVITDIQ..................VNPFYLL-------------------
D0LRP5_HALO1/739-867..AAADLE----G-----R--YASNNFFLVLARRDVGC...............ALNLDGLC-------------------
A4CM25_ROBBH/762-881..AVLDME----Q-----Y--FADQSLYVCTYYNSKP................KTNLWFYL-------------------
D6XZV1_BACIE/524-637..FAYDNN----Q-----T--LTLNSANILIPKIEG..................YDIKYVM-------------------
B5YJE4_THEYD/332-454..AAYDEK----C-----Y--PWMGDVYHLIRKTNLFNL............NFDMSEQEVV-------------------
Q24XG1_DESHY/339-452..FAYDNS----Q-----T--LTLNSANIVIPKLEG..................LNIKYIL-------------------
B0JLC9_MICAN/1017-1136..FTYDNS----Q-----Y--YALNTLVVVNLKKGIN.................FDIKFLL-------------------
B3QU01_CHLT3/277-390..AAYDEK----C-----Y--PWREEFHLVPKVN....................VHERQIV-------------------
A5N0R0_CLOK5/377-495..SALDTK----G-----S--IIEQSLYGIICLDER..................FSPYYIL-------------------
A6GW88_FLAPJ/761-878..IGICEP----K-----I--LTSNTLYNLYMKTED..................YSLKYVF-------------------
Q3IQE9_NATPD/931-1083..FAYDTE----A-----T--HILNTAYLLRATDDSD.................YSLKYLT-------------------
C0R107_BRAHW/240-364IIAALDTE----N-----Y--YSFASTNLIIIKDEFKD...............VYSYELIC-------------------
B0VG24_CLOAI/333-455..AAFDEK----C-----Y--PWMGDVYHLVRENSLFNC............HFDLETEEVV-------------------
A5I1A4_CLOBH/564-681..AAYDEE----G-----I--IIEQSLYGIINLKQN..................FSHKYIL-------------------
C0R104_BRAHW/227-354..AIFDNE----Q-----Y--YSVNTLYSIQFLDGIE.................YNYLYLL-------------------
O25223_HELPY/388-501..FFYDNK----Q-----R--LFLNSANMFVLKENFP.................INAHALK-------------------
R6N9B4_9FIRM/545-657..FAYDDK----Q-----T--LSLNSCNIVIPKIPG..................IKIKYVL-------------------

PF01420

T1S1_METJA/225-407--VAVLTV....E.....S..TFNQGCKGLFQKNNDSVN...TE----------FYAYYLK..FKKN......LLENL..
O25209_HELPY/1-179--VAIAEK....R.....L..CTNQGFKSIIP...NKKI....Y----------FEFLYYL..LKYH......KNNFI..
O25519_HELPY/109-276--INYFNE....K.....F..FAGGLCYPYKVKDTNELL...TK----------FLYFYLK.TNEIQ......IMENL..
O27024_METTH/222-387--SAYIMN...GK.....F..WVNNHAHVIEALP.SKIT.....----------NRFLLHI..LIYL......DLTHY..
O27024_METTH/15-193--VALNTV....E.....C..VFNQGCKALVPK..SHVD...TR----------YFAYYLL..INKK......RLQDL..
T1S_SALTY/7-187--EFPNGY....G........AGSTEYYVLRSI..NGLI....N----------PHWLFAL..VKTK......DFLTNGA
T1S_SALTY/225-410--AGIIPD..........V..YNNANLTENAAKICNLNENIFNR----------FLSLWLRSSYLQD......IINSE..
T1SH_MYCPN/62-225--VFYRNG....K.....F..NASQDCGVLKVKNKKICT....K----------FLSFLLK....IE......APKFV..
T1SA_MYCPN/147-310--VFYRDF....A.....Y..LPAVSLICFVPKE.........E----------FDIRFLF..HALR......AIKFK..
Y1531_METJA/22-203--VAIYEG..........KPEFLLHGMNLLLLRPNKNKI...EP----------YYLLYLL..RHFK......QKNIFKY
T1SH_METJA/22-201--VAIAKN....P.....L..TTNQGFRNIIPK..DGVV...SE----------YLYYLFKTKTMSE......YLKDI..
T1SB_MYCPN/179-342--VFYRDF....S.....Y..LPAVSLICFIPKP.........E----------FNINFLF..HALK......ATKFH..
Q88AU8_PSESM/13-174--AKYQPA....P.....F..NASDDVIALEPIS.KQAT....E----------PALLLIA..SMLT......LQCVP..
Q1WR64_LACS1/1-159--VYFRDF....E.....Y..KMVTHARVFSLIP.KQNI...TR----------SIGLYFQ..TCLS......KHKR...
Q88AU8_PSESM/192-354--VFYQPV....P.....F..YTSKEIQVLR....HHKL...TA----------DSGLILV..ALLR......EQMG...
O25479_HELPY/241-404--VINKDNTPVVNWASGKI..WVNNHAHVLQTKN.ELKL....K----------FLYFYLQ..TI........DVSY...
T1SI_HAEIN/195-369--TVIFDG..........ENSYFQDSNIVWID...NDETLVLNK----------YLYHFY...KIAK......WGIAE..
O25479_HELPY/13-194--HALLIV....D........SLANQQFTFLSKKANCDLALDMK----------FFFYQCF..LLGE......WCKNN..
Q1WR64_LACS1/216-380--MFYQPK....A.....Y..FTGDKIQVFSLNNKYGKL...NE----------NIALYLI..AAVK......RALV...
T1SG_MYCPN/114-279--VFYRNE....K.....F..SCSQNCGLLEVKN.KNKF....S----------SKFLCFA..LKLQ......SKKFV..
T1SI_HAEIN/16-176--ENYSIQWAVGK.....F..WANNHVHVVNGK..EKLN...NR----------FLYHYLT..NM........NFIPF..
T1S1_METJA/17-197--TAINKI....E.....V..ATNQAILGIIPKD.NILE...SE----------FLYYILA..KNKN......YYSKL..
T1SX_MYCPN/10-171--VRLADK....D.....Y..FCGQSSCTLTVLDPLEID...LK----------FAYYALK..SQEE......KITSL..
T1SH_HAEIN/1-179--YLFVDN....DL..DNY..VVSTKFMVIEP...NANI...VL----------PEFLFLL..LISNETTEYFKMIAE..
O28563_ARCFU/140-319--FLLDGY..........Y..VFASYLIRLRPKH.EILH...PH----------FLTFYLI..FSQS......RLKQL..
Y1218_METJA/22-191--IFLGKK....G........ILSSTMVKLEQ...KNKI...MD----------DLYLFYS..LKLKE....SFLKSQ..
T1SH_HAEIN/266-440--VSMTSK....P.....S..HTNQQINSIIP...DDEQ....S----------CEFLYLS..LKQP......SMTKYLK
Y1218_METJA/220-404--LKDIDE....P.....A..ILYQRVGRFIFKSEKIDK....Q----------FLFYLLMSEYFKK......ELSKL..
O26006_HELPY/204-368--FFYRKK....S.....W..YAGQFMRKITPKTEI.ENK.IDL----------RIANYFT..TLLN......ALKRP..
Q1GA73_LACDA/197-372--VAILSQTDYDK.....V..YQNQRVGYFQPVD.........Y----------IDYGFIS..TIVRSELFMMQLESV..
Q9CHS0_LACLA/229-396--HIWSGE....K.....V..IYHYHIWKVELS..KFLD...RN----------FTLQLLE..ADKA......RLLSS..

PF12950

B5ICQ9_ACIB4/763-920---------GILNSKMVH.FYYANITSTI..R-----------GGYMRFIR--------QYLEMIPI
A0ZFG2_NODSP/1317-1435---------SILNSSLMK.FYYETSFPTL...-----------....HVQR--------NELAVLPM
C5CH49_KOSOT/887-1032---------TLLNSKVID.FFLRKLAIER..R-----------GGFVEQKP--------IYVSKIPV
Y3402_METJA/955-1077---------GILNSELISYIYIGKSAIAL..K-----------DDFRQTTL--------EELRELPI
Q12U44_METBU/826-966---------GILNSKLMS.FFYANVYATGSLQ-----------GSYSHVYP--------QHVRNFPI
B9DU79_STRU0/1021-1140---------GILNSRLISLWFFMKFDKFQ..R-----------RLFPQFKV--------NELGDFPI
D0LRP5_HALO1/739-867---------ALLNSALMT.EFFRTIEPRR..G-----------RAFAELKI--------KHIGEFPL
A4CM25_ROBBH/762-881---------ALLNSRLYG.FYFRKYYSEE..D-----------DLFPKIKV--------NELKELPV
D6XZV1_BACIE/524-637---------AILNSRVAQ.FYHTYMFSPL...-----------....KVLK--------KHIESIPI
B5YJE4_THEYD/332-454---------EYLNSDYVK.RYVKDIY.....R-----------EITYHLSI--------TQLKNLPL
Q24XG1_DESHY/339-452---------AILNSRVIQ.YYYSKCFRSV...-----------....KVLR--------SSLARLPI
B0JLC9_MICAN/1017-1136---------GIMNSSLMN.YIYNNKFKST..K-----------TVFSEIQT--------RSISQLPI
B3QU01_CHLT3/277-390---------EYLNSEQVQ.VHIKTLY.....R-----------DLIPHLTR--------LQLAMIPI
A5N0R0_CLOK5/377-495---------GLLNSKLIQ.WYYLNFLITN..A-----------NSTPQIKK--------FSLDRIPI
A6GW88_FLAPJ/761-878---------SVLNSKIIK.MYWLSNYSDS..K-----------QLFPKIKG--------YQLKQLPI
Q3IQE9_NATPD/931-1083---------GLLNSNVLE.FYVKMISPPL..R-----------GGYHRYIT--------KYLEPLPV
C0R107_BRAHW/240-364---------ALLNSKLIN.FYYVKNFTNA..S-----------TLTVNISK--------TFLEKIPM
B0VG24_CLOAI/333-455---------AYLNSDYIK.KYVKDTY.....R-----------EITYHLSI--------TQLKNLPV
A5I1A4_CLOBH/564-681---------GILNSQLMS.WYYKKYLITN..K-----------DSTPQLKK--------YRLNKIPI
C0R104_BRAHW/227-354---------GILNSNLIA.FYFRNKFEEAHVS-----------GGYLRFKK--------IYTSLLPI
O25223_HELPY/388-501---------ELLNSDLMQ.FIFESLFKTH...-----------....KILR--------KDLECLPL
R6N9B4_9FIRM/545-657---------AILNSRIAQ.FIYKKEFNSV...-----------....KILR--------SHIENIPI

PF01420

T1S1_METJA/225-407...SGGSTFKELSKSMLE..NFKIPLPPL.EE......QKQIAKILSSVDK.SIELKK.QKKEKLQR
O25209_HELPY/1-179...NMGEGTTIKGIYNIALGLFKVKIPPTYYE......QQKIARTLSILDQ...KIENNHKINELLH
O25519_HELPY/109-276...VFRGSIPALNKADIE..TLTIPIPPL.EI......QQEIVKILDQFSALTTDLLA.GIPAEIKA
O27024_METTH/222-387...VVGSTRKKLNQGIMR..KIKIPLPPL.EE......QKRISEILQDVDR.RLELLT.ERKVKLEN
O27024_METTH/15-193...SGGSTFKELNKKTLE..KIYLPVPPL.EE......QKRISEILQDVDG...AIEKVNKEIGVTE
T1S_SALTY/7-187LNMSGSVGHKRVTKEFLE..NYGVPVPPL.AE......QKVIAEKLDTLLA.QVDSTK.ARLEQIPQ
T1S_SALTY/225-410...IKSGAQGKLALARIK..SLPLILPPL.QE......QHEIVRRVEQLFAYADTIEK.QVNNALTR
T1SH_MYCPN/62-225...HNLASRPKLSQKVMA..EIELSFPPL.EI......QEKIADILFAFEKLCNDLVE.GIPAEIEM
T1SA_MYCPN/147-310...KQGSATGQLTVAQFK..EYGIHVPSL.KK......QKEIAAILDPLYSFFTDLNE.GIPAEIEL
Y1531_METJA/22-203.IAKRAVNQSSINQTQLK..HLKIPLPPL.EE......QKQIAKILSDFDN....LIG.TINKQIEV
T1SH_METJA/22-201...SGGSTFPELKGSTLK..EVEIPYPSP.EE......QQKIATVLSYFDD...LIENKKKQNEILE
T1SB_MYCPN/179-342...KQGSGTGQLTMAQFK..EYQVYIPSL.KK......QQEIAATLDPLYY.IFANSNWGIYKEIEL
Q88AU8_PSESM/13-174...KFGFGY.KLTLHRLD..RQKIMIPVLTNAD...GEQVVNWSGLTRHGK........RLLNEAKT
Q1WR64_LACS1/1-159...KFSYDN.MCVFTKLE..NETIELPIA.DA......GKLDVEFIENYIR...QLEA.DRLQQLEA
Q88AU8_PSESM/192-354...KFQWGN.GASLERLK..ATRIMVPAMVGAD...GEDVVDWDGLSRYGR........ALRARVEL
O25479_HELPY/241-404...CVAGTPPKINQENLK..KIAIPIPPL.EI......QQEIVKILDQFSILTTDLLA.GIPAEIKA
T1SI_HAEIN/195-369.....GGTIQRLYNDNLK..KVKISIPPL.KE......QHRIVSILDKFETLTNSITE.GLPLAIEQ
O25479_HELPY/13-194...INVSGFASVDMTAFK..KYKFPIPPL.EI......QQEIVKILDAFTELNTELNT.ELNTELKA
Q1WR64_LACS1/216-380...NFAWGQSSFALEAIS..ELNITLPID.NN......NQLHLDYMENYIR...AIEKLTIKDVVEY
T1SG_MYCPN/114-279...NYASAIPVLTIKRIA..EIELSFPPL.EI......QEKIADILFAFEKLCNDLTE.GIPAEIEL
T1SI_HAEIN/16-176...LAGKERAKLTKAKLQ..QIPIPIPPL.SV......QTEIVKILDALTALTSELTS.ELTSELTS
T1S1_METJA/17-197...GMQTTQKNLNAQIVK..SFKIPLPPL.EE......QKQIAKILTKIDE.GIEIIE.KSINKLER
T1SX_MYCPN/10-171...ASGTTIKNIRLSDLK..DLPIPLVKSIQD......QRTIAHALSVFDL...RIEHLNELIEVNR
T1SH_HAEIN/1-179...SRSGTFPQITFDSVS..SLSLNIPDK.ET......QQKILDIITPLDD.KIELNT.QINQTLEQ
O28563_ARCFU/140-319..ATVAVHQANINATNLK..KFKIPLPPL.PE......QQKIAEILSTVDK.KLELER.KRKEKLER
Y1218_METJA/22-191...TKGTGIPHVDKKIFE..NIKIPLPPL.EE......QKQIAKILSDFDN.LIGTIN.KQIEVLNK
T1SH_HAEIN/266-440DLASGGTATLNLNTSTFS..KIEIITP...S.......KEIIYIFQKKVVS...IFEK.TLSNSIEN
Y1218_METJA/220-404...LIGTDQPYIRTPVLL..NIKIPLPHL.EE......QKAMAERLKSIDN.LIEIKR.KEKEQIEK
O26006_HELPY/204-368....LLSVLVRDIDKTFR..EQKIQLPLK.PTAKTQTLDGIDFDFMHTLIN...ALMK.QTIQ....
Q1GA73_LACDA/197-372...LVSGAQPNVSSEEID..SFNFMIPILVQE......QQKIGQFFKQLDD.TIALHQ.QKIN....
Q9CHS0_LACLA/229-396...TNGSTMIHVTKGDME..SKIVSIPNI.DE......QKQIGSFFKQLDN.TITLHQ.RKLDLLKE

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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