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1  structure 610  species 0  interactions 2118  sequences 73  architectures

Clan: LCCL-domain (CL0513)


LCCL-domain like Add an annotation

This superfamily is characterised by an unusual fold exemplified in PDB:1jbi. Vertebrate members are the cysteine-rich secretory protein LCCL domain-containing proteins including Colchin. The fungal members are found to be necessary for histone de-acetylation.

This clan contains 2 families and the total number of domains in the clan is 2118. The clan was built by P Coggill.


This clan contains the following 2 member families:


External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
LCCL (PF03815) 1680 (79.3%) View
Rxt3 (PF08642) 438 (20.7%) View
Total: 2 Total: 2118 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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