Sequence alignment for CL0513

PF03815

Q4WUJ0_ASPFU/168-298LSCHSRLWSNATNCG.LDGDACR.PFDDGAFAFRCPATC..SAAMLLEPYFIG--PQEINYRTLVIGGELGGGNGSDYGV
CRLD2_MOUSE/387-486VDCHATVAQLC.........PFE.KPATHCPRIQCPARC..GEEPSYWAPVYG--TN......................I
CRLD2_MOUSE/286-377VHCDTKMKDSC..............KGSTCNRYQCPAGC..LSNK...AKVFG--SL......................F
COCH_HUMAN/32-121ITCFTRGLDIR................KEKADVLCPGGC..PLEE...FSVYG--NI......................V
Q3S621_TOXGO/1140-1234LTCRDDGAFAL.........KMN...PGDKELVICPPGC.LAASE...GTVYG--TK......................V
Q4N1E8_THEPA/906-990LGCSDTIESEN..........FN.GPNGKSFLISCTKSC..IDPD...LTLKG--TK......................V
LFC_TACTR/329-421VDCDSKAVDFL.............DDVGEPVRIHCPAGC..SLTA...GTVWG--TA......................I
Q8IK83_PLAF7/754-852INCETTGMEDS..........FH.SIVNTNIVVLCPLGC..DDEKYHDASIYG--SR.....................GT
Q8IM24_PLAF7/1171-1264FTCSTDGQFIL.........NLS...VGEKRTINCPSNC.NIIKD....KIYG--TN......................I
Q3S622_TOXGO/1034-1130LRCEDTLLRPE..........FS.GVTGHQILVSCPADC..AHST...GPLHG--CK......................I
CRLD1_MOUSE/293-384VSCEVRLRDQC..............KGTTCNRYECPAGC..LDSK...AKVIG--SV......................H
Q4Y3E4_PLACH/7-99FTCFTDGSFLN.............FLMGSTKNIICPENCHKIDK.....QIYG--TN......................T
Q4SVD9_TETNG/359-444VNCDTKLRDQC..............KGTTCNRYECLPGC..LERP...GKVIG--TG......................F
Q4YW57_PLABA/727-825LNCDTTLKQAI.........EIE.KFVGNEYLFKCPYDCLKRNTE...ATVIG--GEG....................NI
Q8AW56_DANRE/31-120ISCGTRAVDLS................DTHLLVLCPANC..SLWS...LSVFG--SG......................V
Q3S621_TOXGO/278-380VECHTRALELY.........SRI.PENIGIFKVRCPMNC.QASTF...ASVDG--SS......................I
Q5CNE9_CRYHO/562-661LSCESRFSDMN........VFKS.SPLLTSILVKCPTSC.NPENG...GVVIG--SD......................V
Q2UA88_ASPOR/147-275LTCRATLWEYGNECG.LNGNDCR.PFTAATIPFRCPANC..RDAKLAAPHMVG--NQTYSYKGLVVG..GPQPGSDDTPV
Q5B418_EMENI/329-457LSCSSRLWSNATNCG.LDGDYCR.PFDGETFAFRCPAGC..SGFMVLEPYFVG--PKEINYQHLVIG..GAAAESQPDSV
O61139_CRYPV/740-837IDCDTVAYKNP.........IFE.GPINTNIIVQCPPGC..AEYK...TKVYG--SD.....................GV
Q8IM24_PLAF7/672-769LTCFDKMLSKS.........NLSVATTGDVFLASCPEKC..DEEV...GIVKG--TF......................L
Q5CLR6_CRYHO/1149-1244LTCSDTASFIF.........QLP...VGERELVSCPSNC.GLESD...AKVYG--MD......................I
Q3S621_TOXGO/1033-1129LTCEDTLRREE..........FN.GITEQRFLVSCPSDC..TSKV...AQVYG--SK......................V
Q5H993_HUMAN/156-248ITCLERASHYL................KTEYSKFCPAGC..RDVA...GDISG--NMV....................DG
Q4YUE0_PLABA/1079-1193LNCSDNLLSER..........FN.GKIGAQFLVSCLEDC..TNSK...YIVKG--SN.....................NY
Q8IKS0_PLAF7/726-824LDCQSSLKETN.........EIE.KMIGNEYLIKCPHDCLERDIE...ESVIG--GEG....................NI
Q2GQN4_CHAGB/129-252IDCVDTLWKRNNECG.LDGINCR.PFSNTSFAFRCPADC..ASVRVLNPHHVG--NQDVNFRPL.......VVGGGGNGP
Q7SY04_DANRE/303-395VACDTRLRDQC..............KGTTCNRYECPPGC..FYNY...GKVIG--SG......................H
Q3S622_TOXGO/1141-1235LTCADNGSFVL.........KLG...IGERELVICPPHC.SAVSN...RAVYG--AG......................F
Q3S622_TOXGO/286-382VDCYTRAADIF.........NTT.PLGMEVVKVRCPQNC.QASEF...ARVLG--ST......................I
Q5NTW9_CHICK/37-126IDCDVKAGKII................NPEFIAKCPPGC..QDVK...YRVYG--TD......................I
A1A526_HUMAN/44-133INCDVKAGKII................DPEFIVKCPAGC..QDPK...YHVYG--TD......................V
Q5AU59_EMENI/149-276LSCSTTFWSSGNGCG.LNGNDCR.PFTGEATAFRCPANC..RDTKILESYTIG--NETISYRGLVVG..GPQPGSDEPGV
Q4SMW7_TETNG/327-426ITCETTAAQLC..........SYQKPAKHCPRLYCQRNC..LEENPHLSRVIG--TR......................I
Q5CLR6_CRYHO/300-397IDCNTRAIDIV.........PRA.PVTTITFKVKCPVNC.GSEKF...ATIYG--TG......................I
Q3S622_TOXGO/669-764LTCSDRPVTRR.........DMA.GGPGTIFIASCPDGC..SEAP...GAVKG--TF......................V
CRLD2_XENTR/291-382IKCATKMRDSC..............KGSTCNRYKCPPGC..INSK...AKVFG--TL......................F
Q4U8P9_THEAN/1093-1187LSCQDTAVFVL.........KMH...IGTRVLLDCPPGC.KDAKP...YNVFG--TG......................V
Q4N1E8_THEPA/188-285VMCNTRAVDIY.........SGT.FVKPFNITVRCPMNC.NNDPL...MSIEG--SS......................L
Q4Y8D6_PLACH/571-667LSCDYTFENIT.............LDNNQTIVARCLPNC..FNQK...NDIFG--SY......................I
Q8IM24_PLAF7/277-384IDCHIRAIDLINTN...NINKLL.QNKVQIFKVRCPQNC.HNSEF...AIIEG--SS......................I
Q3S621_TOXGO/663-758LNCGDRPLSQK.........QMG.GQAGAMFVATCPEGC..SEEP...GSLKG--TY......................I
Q4XZL5_PLACH/752-850IDCDTTALDDD..........FN.GIVNTNIVALCPLGC..DHERFKEFHVYG--SN.....................GV
Q28NH5_JANSC/183-268AQCPANALSLS.................ANTQCSCPANP........GGTIWG--SN......................V
Q6GL27_XENTR/157-249ITCLARSNHYK................DIEYSRFCPAGC..KDVA...GDISG--DVV....................EG
Q4XHB8_PLACH/31-138IDCHIRANDLIDTTKSLNNSFVL.QNKVHIFKVRCPQNC.HSSDF...SIIEG--TS......................I
Q28NX7_JANSC/137-231ISWSDDVDAIG..........YG.DRVGESVTVTCPADR..FGA....GQVWG--TD......................V
Q4Y340_PLACH/467-582LNCDDTLNDIP........DVIP.LIYGDKFVVSCPYNC.IKDVESNNKTVYG--SD......................L
Q4SH26_TETNG/161-253ISCLRRGSHFS................SQHVSVYCPAGC..RNVT...EDVWG--SWE....................QG
Q28NX7_JANSC/19-119LLCATPSLADWSAN...LIARGL.DTPGATGQIECPPN....GAV...ATVWG--TG......................T
Q8IM24_PLAF7/1059-1160LKCQDNLLSEQ..........FN.GKIGSQFLVSCIENC..TKSK...YFIKG--TN.....................NY
Q4N5G4_THEPA/751-847LDCSDSLGRSK.........KIF.GSLNTSVIVRCDEDC.SQKDN...LFIYG--TN.....................GL
Q4N2Y3_THEPA/528-626LACNSRITDNS.........DLP.TKPGSKFNVKCPQNCHETYEN...YEVEG--GKD....................GL
A1L2A7_DANRE/159-234ITCLEKGEHFS................EAEFSKFCPAGC..LIDF...GEVSG--TIP....................HG
CRLD2_XENTR/392-491IDCYTTVAEIC..........QFVKPATHCPRFNCPAHC..KNEPSYWAPVIG--TN......................I
Q4TAR6_TETNG/164-256ITCLDKGSDFP................EAEFSKYCPAGC..LTST...EGISG--TMP....................KG
Q4N1E8_THEPA/573-671LSCYDTLTSHS.........EFQ.GEFGSFKVASCPMGC..MDEP...ASIKG--TY......................V
Q4XHC4_PLACH/3-100LSCFDKISSKA.........ELSKGNVGDIFLVSCPEKC..DEDS...GVIKG--TF......................V
Q5CLR6_CRYHO/1043-1138IKCDTNLDNAR...........F.SSKANKFRVECPAGC..SKSR...YPVKG--HK......................V
A0LH15_SYNFM/30-122LPDPGTLNQME.........NVA.PGTTMFFNVTGKTTG.........GSLWG--TD......................Y
COCH_CHICK/28-117ITCFTRGLDLR................KETEDVLCPANC..PLWQ...FYVFG--DG......................I
CRLD1_MOUSE/394-492VTCETTVEQLC..........PFHKPASHCPRVYCPRNC..MQSNPHYARVIG--TR......................I
Q14089_HUMAN/117-217VIDKQRSNYLFG.......HCIQ.FFWNLSSVSTAPAGC..LLPF...AEISG--TIP....................HG
A1K4X6_AZOSB/246-318CTCGTVVSSQ......................................GSVWG--SD......................I
A1C540_ASPCL/149-277LSCATTFWEHGNECG.LNGNDCR.PFSASTVAFRCPANC..RDAKLLSPHTVG--NHTFSYQRLVVG..GPQPGSSEPGV
Q2PFL5_MACFA/166-258ITCLDTASNFL................EPEFSKYCPAGC..LLPF...AEISG--TIP....................HG
Q4RPZ7_TETNG/8-97IECDVRAGKIN................LPEFIAKCPAHC..KESK...QQVYG--TG......................V
Q5CLR6_CRYHO/681-774FDCNDSPVSIK.............GAVGTGAIIACPSKC..SKAS...SHIKG--SY......................I

PF08642

Q4X0R9_ASPFU/840-962FTVRVPRFRI................DAGR....REEIC----AR---RALWG..TG----------------------I
Q6BS67_DEBHA/387-500LEIKIPYKFI................KLFKEDLDDDNIP----LK---RQIWGGASA----------------------V
Q7SC37_NEUCR/1024-1118LTVKISKTHL................TPEA....REEIT----SR---RAVWG..TD----------------------I
Q757D6_ASHGO/124-245VTVELSAEDL................ESALAT.GENARV----RN---RELWG..VD----------------------V
Q5AZK0_EMENI/859-982FTIRVPRFRI................DNSH....REEIC----AR---RALWG..TG----------------------I
Q5KAD1_CRYNJ/817-931IVVRIGGGFLGRGWRVRGEPGWDDAGTKQVGNVVCGAED----PK---RACWG..TD----------------------V
Q6CF00_YARLI/304-432IQVLIPRKHL................RKE.....SNILV----QR---REIWG..TD----------------------I
Q6CWM7_KLULA/160-284LTIQIDSIYL................QQVARS..ENIRY----QN---REIWG..TD----------------------I
Q8RWV9_ARATH/602-686LEVRIPAEHV................TA......TNRQV----RG---GQLWG..TD----------------------I
Q6FWF5_CANGA/150-281ITISIKYEDL................MKSFNDSGECPRT----FN---NEIWG..CD----------------------V
RXT3_YEAST/139-253ATLKITYEDI................QASFNN.IESPRK----RN---NEIWG..CD----------------------I
Q59ZF1_CANAL/376-497IEIKIPFRHI................ILFKQDIANELIT----..---RELWGGASG----------------------I
YC57_SCHPO/220-301VRVTIDIKWL................NAA.....INPRL----CR---REIWG..TD----------------------V

PF03815

Q4WUJ0_ASPFU/168-298YRGDSAICPAALHAGLI................SDAKGG-----------------------------------------
CRLD2_MOUSE/387-486YADTSSICKAAVHAGVI................VDEVGG-----------------------------------------
CRLD2_MOUSE/286-377YESSSSICRAAIHYGVI.................DDRGG-----------------------------------------
COCH_HUMAN/32-121YASVSSICGAAVHRGVI.................SNSGG-----------------------------------------
Q3S621_TOXGO/1140-1234YSPISSVCRAAIHSGHL.................TNEGG-----------------------------------------
Q4N1E8_THEPA/906-990YTSDSSICKAALHSGVI.................PKDGG-----------------------------------------
LFC_TACTR/329-421YHELSSVCRAAIHAGKL.................PNSGG-----------------------------------------
Q8IK83_PLAF7/754-852YSDNSSICRAAIHSDII.................DNKGG-----------------------------------------
Q8IM24_PLAF7/1171-1264YSPTSVLCKAAIHSGAL.................SNQGG-----------------------------------------
Q3S622_TOXGO/1034-1130YSADSSICKAALHMGAI.................QRHGG-----------------------------------------
CRLD1_MOUSE/293-384YEMQSSICRAAIHYGII.................DNEGG-----------------------------------------
Q4Y3E4_PLACH/7-99YSPLSSVCKAAIHAGVI.................SIKGG-----------------------------------------
Q4SVD9_TETNG/359-444YDMQSSVCGAALHSGVI.................DNDGG-----------------------------------------
Q4YW57_PLABA/727-825YSEDSSICLSSIHAGVY..................DKHY-----------------------------------------
Q8AW56_DANRE/31-120YASISSICGAAIHRGII.................GLSGG-----------------------------------------
Q3S621_TOXGO/278-380HPMASSICAAAIHDGVL.................SPSGG-----------------------------------------
Q5CNE9_CRYHO/562-661YRDDSSICLAAMHANTL.................NRSTG-----------------------------------------
Q2UA88_ASPOR/147-275YRADSFICQAAIHAGVI................TNTIGG-----------------------------------------
Q5B418_EMENI/329-457YRGDSSICQAAMHAGLL................EDSKGG-----------------------------------------
O61139_CRYPV/740-837YSEKSSICKAALQVGVI................STNTGG-----------------------------------------
Q8IM24_PLAF7/672-769YTYDSPICKSAIHSGVL................PNNIAE-----------------------------------------
Q5CLR6_CRYHO/1149-1244YSPISSICRAAIHASKL................SSGTAG-----------------------------------------
Q3S621_TOXGO/1033-1129YSEASSLCKAALHSGAL.................ATQGG-----------------------------------------
Q5H993_HUMAN/156-248YRDTSLLCKAAIHAGII................ADELGG-----------------------------------------
Q4YUE0_PLABA/1079-1193YTPDTSICKAVMHSGIMHKTRNTHKSNEHDEDNNKTNNN-----------------------------------------
Q8IKS0_PLAF7/726-824YSEDSSICLSAIHAGIY..................DKHY-----------------------------------------
Q2GQN4_CHAGB/129-252YRGDSFLCGAAIHAGVI................RDTTGG-----------------------------------------
Q7SY04_DANRE/303-395YADNSSICRAAIHAGVI................QSDSGG-----------------------------------------
Q3S622_TOXGO/1141-1235YSPISSVCRAAIHAGAL.................TDEGG-----------------------------------------
Q3S622_TOXGO/286-382HPSISSVCAAAVNDGVL.................SPSGG-----------------------------------------
Q5NTW9_CHICK/37-126YASFSSACSAAIHSGAI.................DNTGG-----------------------------------------
A1A526_HUMAN/44-133YASYSSVCGAAVHSGVL.................DNSGG-----------------------------------------
Q5AU59_EMENI/149-276YRADSFICQAAIHAGVI.................DNDGG-----------------------------------------
Q4SMW7_TETNG/327-426YSDKSSICRAAIHAGVI................RNEAGG-----------------------------------------
Q5CLR6_CRYHO/300-397HAASSSICKSAVFDNIL.................TPSGG-----------------------------------------
Q3S622_TOXGO/669-764YTDDSPICKAAIHAGAL.................EASGG-----------------------------------------
CRLD2_XENTR/291-382YDSMSSICRAAIHYGVI.................DNSGG-----------------------------------------
Q4U8P9_THEAN/1093-1187YSPTSSLCQSAIHSGKL.................DNDGG-----------------------------------------
Q4N1E8_THEPA/188-285HPSSTSICGAAIYDGAT.................SPSGG-----------------------------------------
Q4Y8D6_PLACH/571-667YAPHSPICKSAIHSGII.................TNLGG-----------------------------------------
Q8IM24_PLAF7/277-384HPSSTSICAAAIHDGSI.................SPSGG-----------------------------------------
Q3S621_TOXGO/663-758YTDDSPICKAAIHVGVV.................GPLGG-----------------------------------------
Q4XZL5_PLACH/752-850YSDSSSICRASIHAGVI.................DKQGG-----------------------------------------
Q28NH5_JANSC/183-268YTADSNICLAALHAGAM.................PITGG-----------------------------------------
Q6GL27_XENTR/157-249YRDTSLLCKAAIHAGVI................ADELGG-----------------------------------------
Q4XHB8_PLACH/31-138HPASTSICAAAIYDGSL.................TESGG-----------------------------------------
Q28NX7_JANSC/137-231YSSDSPICNAAVHRGLM................IAAEGG-----------------------------------------
Q4Y340_PLACH/467-582YSLDSPICKAAVHSGVCLKNGNNT..DVNTLNNYEEECK-----------------------------------------
Q4SH26_TETNG/161-253YRDTSVLCKSAVHAGVI................SDGQGG-----------------------------------------
Q28NX7_JANSC/19-119YTSDSSICTAALHYGWI................TLDVGG-----------------------------------------
Q8IM24_PLAF7/1059-1160YTPDSSICKAAIHAGIYKP.............NMGNKNN-----------------------------------------
Q4N5G4_THEPA/751-847YSDHSSICLAAIHAGII..................SSHG-----------------------------------------
Q4N2Y3_THEPA/528-626YSFNSSVCLSAVHAGEY.................DNKSG-----------------------------------------
A1L2A7_DANRE/159-234YRDSSPLCLAGIHAGVL................SNTLGG-----------------------------------------
CRLD2_XENTR/392-491YADSSSICKTAVHAGVI................KDGEGG-----------------------------------------
Q4TAR6_TETNG/164-256YRESSPLCVAAVHAGVI................SNAVGG-----------------------------------------
Q4N1E8_THEPA/573-671YTRDSSICKAAIHSGVL.................DNSGG-----------------------------------------
Q4XHC4_PLACH/3-100YTFDSYICKAAIHAGVL................SSNVAD-----------------------------------------
Q5CLR6_CRYHO/1043-1138YSPKSSICQAAMHMGII.................SDTGG-----------------------------------------
A0LH15_SYNFM/30-122YTTDSSLAMAAVHSGAI................RNGQTG-----------------------------------------
COCH_CHICK/28-117YASLSSVCGAAIHRGVI.................TNAGG-----------------------------------------
CRLD1_MOUSE/394-492YSDLSSICRAAVHAGVV.................RNHGG-----------------------------------------
Q14089_HUMAN/117-217YRDSSPLCMAGVHAGVV................SNTLGG-----------------------------------------
A1K4X6_AZOSB/246-318YTADSALCKAAVHAGVI.................PRSGG-----------------------------------------
A1C540_ASPCL/149-277YRADSFVCQAAIHAGVI................TNAVGG-----------------------------------------
Q2PFL5_MACFA/166-258YRDSSPLCMAGVHAGVV................SNTLGG-----------------------------------------
Q4RPZ7_TETNG/8-97FASISSICNAAIHSGVI.................TNAGG-----------------------------------------
Q5CLR6_CRYHO/681-774YSDDTPVCKAAIHAGII................TDEVGG-----------------------------------------

PF08642

Q4X0R9_ASPFU/840-962YTDDSDPVAAAMHSGFF----------------RGAWSEEIDVDML.............DLEIRDAYQHAPTTAEDMGLT
Q6BS67_DEBHA/387-500YTDDSDILLVLAHLGLF----------------NGKIDLTEWN...................EKWTSDDIITPLDAK...
Q7SC37_NEUCR/1024-1118YTDDSDVIAACIHA...----------------......................................DEAGSEV.Y
Q757D6_ASHGO/124-245YTCDSDPLLVLVHCGVL----------------DAELSGQGAGS................GPRRRTPANRANPDCVTRGV
Q5AZK0_EMENI/859-982YTDDSDPVAAAIHSGFI----------------RGAWGEDVDPDML.............DLEIKDSFQHAPKTAKDMGLD
Q5KAD1_CRYNJ/817-931YTDDSDLGLILVHAGWI----------------RWSALPSL.......................QSPQDRKKDEQEF...
Q6CF00_YARLI/304-432YTDDSDIVSVLYHTGVL----------------PTRAQVDAFYSTLRAQEEGDADDTTDGHLEDEHPVTVGPNSHLVTST
Q6CWM7_KLULA/160-284YTDDSDIILVLQHCGVL----------------PFSEPLDQNSNGKPSN......VHSLKTKLRRTPTNMSDQNSVT...
Q8RWV9_ARATH/602-686YTDDSDLVAVLMHTGYC----------------RPTASP.........................................
Q6FWF5_CANGA/150-281YTDDTDPILALRHCGFT----------------CLDPPPLTPTHFKGKAS....HKPSTPAPLRRTPVNQTNKDNVV...
RXT3_YEAST/139-253YSDDSDPILVLRHCGFK----------------IGAPSGGSFH..................KLRRTPVNVTNQDNVT...
Q59ZF1_CANAL/376-497YTDDSDILQVLMHLGLF----------------NNTIDLSIWN...................KKWTTKDLIKPLQSQLDN
YC57_SCHPO/220-301YTDDSDIATILAHCGCF----------------SL.............................................

PF03815

Q4WUJ0_ASPFU/168-298-----------------CGVLRRTGEQSNFLSS..E....RNGISSIAFPSN..FPL....SF
CRLD2_MOUSE/387-486-----------------YADVMPVDKKKSYVGS..L....RNGVQS...ESL..NTP..QNGN
CRLD2_MOUSE/286-377-----------------LVDVTRNGMVPFFVKS..Q....KNGMES...LSK..YKP..SSSF
COCH_HUMAN/32-121-----------------PVRVYSLPGRENYSSV..D....ANGIQS...QML..SRW..SASF
Q3S621_TOXGO/1140-1234-----------------EVELQATGQHEEFKGS..D....KNGIQS...VNS..GWY..LRAI
Q4N1E8_THEPA/906-990-----------------EAILTVLNGLSEYGNC..H...GHFG..................HF
LFC_TACTR/329-421-----------------AVHVVNNGPYSDFLGS..D....LNGIKS...EEL..KSL..ARSF
Q8IK83_PLAF7/754-852-----------------LVNVTIESGMDHYVGS..I....NNNIES...ISL..NKN..EKGL
Q8IM24_PLAF7/1171-1264-----------------LVEIIVGTGQEEFKGS..T....QNNVES...FSS..NNH..SRSI
Q3S622_TOXGO/1034-1130-----------------EAVFTLHDGMPSYAAS..R...GHYGVLS..IATN..TPQ..VLSF
CRLD1_MOUSE/293-384-----------------WVDVTRQGRKHYFIKS..N....RNGIQT...IGK..YHS..ANSF
Q4Y3E4_PLACH/7-99-----------------QIQVVVGKGQQEFKPS..T....QNNVQS...YIA..EKQ..DRSF
Q4SVD9_TETNG/359-444-----------------WLDVTRLGRKQPFIKS..Y....RNGIQS...VG..........LF
Q4YW57_PLABA/727-825-----------------LINLRVLNALGEYEGV..Y....QNGIIS...DSY..IND..SQEV
Q8AW56_DANRE/31-120-----------------PVEVHGLQGRTNYLSS..Y....AHGVQS...QSL..SQW..SASF
Q3S621_TOXGO/278-380-----------------EVVVSVVGELPEYTGSTLY....PTGTVS...TSFRSSPDIPSASF
Q5CNE9_CRYHO/562-661-----------------LAQITPIEGLESYGAS..I....KNGISS...VAY..TGKRWKKSF
Q2UA88_ASPOR/147-275-----------------CGVLKLEGATHSFPAS..K....QNGISSVGFPST..FPK....SF
Q5B418_EMENI/329-457-----------------CGILRRTGEQKNFPAV..D....RNEISSVDFPSH..FPL....SF
O61139_CRYPV/740-837-----------------MFNVALEGPKNSYEGS..T....KNEIES...EKL..SGI..PTRS
Q8IM24_PLAF7/672-769-----------------DIVLSIAHTHNNFIGT..K....RNNIES...HDF..KGT..SKSF
Q5CLR6_CRYHO/1149-1244-----------------EIQIEVGPEQFHFEQS..N....RNGIQS...QST..GYY..IRSF
Q3S621_TOXGO/1033-1129-----------------EVIIVTHSGLKSYSGS..T...GKNGVSS..VGED..EPQ..LRSF
Q5H993_HUMAN/156-248-----------------QISVLQRKGISRYEGI..L....ANGVLS...RDG..SLS..DKRF
Q4YUE0_PLABA/1079-1193-----------------SFIIKIVEGLTEYKSS..R...GHYGIVS..KPEK..QSQ..LRSF
Q8IKS0_PLAF7/726-824-----------------LIHLRVINALNEYGGF..F....QNGIIS...ESF..FNN..TQEV
Q2GQN4_CHAGB/129-252-----------------CGVATLVGEYYQYFSS..S....QHNIESIPFDSY..FPL....SF
Q7SY04_DANRE/303-395-----------------YVDVMPVDKRKQHKGS..Y....QNGISS...ESL..QNP..PGGK
Q3S622_TOXGO/1141-1235-----------------EVEIEAGPPHEAFVGS..E....GFGITS...QKS..GSY..LRSF
Q3S622_TOXGO/286-382-----------------EVVVAIVDSLPSYSGL..S....YAGIDA...GDF..HRS..PEKA
Q5NTW9_CHICK/37-126-----------------KILVQKVAGHAGYRGS..F....SNGVRS...LSL..PRW..RESF
A1A526_HUMAN/44-133-----------------KILVRKVAGQSGYKGS..Y....SNGVQS...LSL..PRW..RESF
Q5AU59_EMENI/149-276-----------------CGVARLEGAAHSFHAS..K....RNGIKSIGFPST..FPK....SF
Q4SMW7_TETNG/327-426-----------------YIDVMPMDMKKHYTAS..Y....QNGIFS...ESL..HIP..SRGE
Q5CLR6_CRYHO/300-397-----------------ELVLTIVPSLPKYFGG..K...GAFSIES...SDF..FPK..PGSE
Q3S622_TOXGO/669-764-----------------DIVVQIGHPQKSYEST..D....QYNVHS...DPS..GPH..PRSF
CRLD2_XENTR/291-382-----------------LVDITRKGRLQFFVKS..T....RNSVES...ISK..FKP..ANSF
Q4U8P9_THEAN/1093-1187-----------------EVEIEVEGERNTFDSN..E....SNGILS...QSS..GHY..LKSF
Q4N1E8_THEPA/188-285-----------------QVVISIVQSMAKYFGG..T...GYNGLKS...EDY..EPP..ADKN
Q4Y8D6_PLACH/571-667-----------------LIEITKLTNITQSFST..TTDITRNGVKA...IIT..DNK..NKDS
Q8IM24_PLAF7/277-384-----------------EIIVTVASELNHYYTIKEK...IFNELEA...LDF..SAKADEKNF
Q3S621_TOXGO/663-758-----------------NIVVVLGEGQDSFMES..E....RNGVKS...ESF..GRY..DRTF
Q4XZL5_PLACH/752-850-----------------LVNVAIESGLDYYKGS..I....SNNIES...ISL..NKG..GNEA
Q28NH5_JANSC/183-268-----------------NISITLGGRLETFTGT..A....QNGVTS...NAW..GAY..DTSF
Q6GL27_XENTR/157-249-----------------QIQVNQHKGISRYRGF..L....ANGILS...KDG..SLS..DHRV
Q4XHB8_PLACH/31-138-----------------EIIVTITKGLNYYYAMDFR....YFELLSDIGQNF.......LKYY
Q28NX7_JANSC/137-231-----------------TVTILILGEQPAFTGS..T....RNGVTT...ADY..TAW..PRSY
Q4Y340_PLACH/467-582-----------------FLLMIKEVNGSNFIGK..L....QNNVLS...MNK..NVE..DQNK
Q4SH26_TETNG/161-253-----------------HVAVTRGRSLTLYESA..F....ANGILS...KMG..SLS..DKKL
Q28NX7_JANSC/19-119-----------------LVGFRQVAGLDRYEGT..S....QNGVTT...LDY..GSW..NSSF
Q8IM24_PLAF7/1059-1160-----------------TFVIRIVEGLLEYKSS..R...GHFGILS..KSEK..QSQ..LRSF
Q4N5G4_THEPA/751-847-----------------SFVVSIENGRKYYDGD..K....QNGIQS...YFY..NKT..WHGL
Q4N2Y3_THEPA/528-626-----------------.LQVEIVSSPGELDGF..F....QNGINS...ASV..STT..LGES
A1L2A7_DANRE/159-234-----------------.......................ADQCGQ...QQR..HPT..LRKL
CRLD2_XENTR/392-491-----------------YVDVMPVEKKKHYFGS..N....KNGIQS...DSI..QNH..KEGQ
Q4TAR6_TETNG/164-256-----------------RISVVNSKGIHHYEAT..V....ANNVTS...TGG..SWS..NSLF
Q4N1E8_THEPA/573-671-----------------EIVVIIAYPQEHFYGT..S....MNGVESLSLSRS..GDD..SREK
Q4XHC4_PLACH/3-100-----------------DVVLIITHSRNKFIGT..K....RNNVES...KEF..NGE..SKSF
Q5CLR6_CRYHO/1043-1138-----------------EFVVALYPGLKQYTGAAGK....NNIVST...DEN..TPQ..TRSF
A0LH15_SYNFM/30-122-----------------VVKVIFYPGRAQYAGS..T....RYGVTS...SSW..GSY..ELSF
COCH_CHICK/28-117-----------------AVRVQTLPGQENYPAV..H....ANGIQS...QVL..SRW..ASSF
CRLD1_MOUSE/394-492-----------------YVDVMPVDKRKMYTAS..F....QNGIFS...ESL..QNP..TGGK
Q14089_HUMAN/117-217-----------------QISVVISKGIPYYESS..L....ANNVTS...VVG..HLI..LQVF
A1K4X6_AZOSB/246-318-----------------RVVVERVDGRELYVGT..S....RNGIGT...SDY..GPH..HPAI
A1C540_ASPCL/149-277-----------------CGVVKLEGAAHTFPAS..K....QNGIQSVGFPST..FPK....SF
Q2PFL5_MACFA/166-258-----------------QISVVISKGIPYYESS..L....ANNVTS...VVG..HLS..TSLF
Q4RPZ7_TETNG/8-97-----------------KVIVKKMAGQNIYKGS..N....SNGVRS...LSL..PKW..RESF
Q5CLR6_CRYHO/681-774-----------------EVVITFVSGQKQYFGS..F....NNGIQS...RSI..ETS..ASKS

PF08642

Q4X0R9_ASPFU/840-962GD.RPRIPPVPPTDKDLHITLLILPKLERYESS--V----LFGLKS---RSW--D--------
Q6BS67_DEBHA/387-500ND.......PNEIHGDLSVTILLLPSLPDYHGY--Y----ANGINS---RSW--I--------
Q7SC37_NEUCR/1024-1118SEPPRNGPMAVPANRDLHVTLVILPKLEKYAST--T----RFGIKS---REW--G--------
Q757D6_ASHGO/124-245SAAPSVRRGAYHF..DVRAQLLMLPPLQRYASA--E----RFGLQS---REW--N--------
Q5AZK0_EMENI/859-982GDQRPKIPPPPPSGKDLHITLLILPKLERYESS--V----LFGLKS---RVW--E--------
Q5KAD1_CRYNJ/817-931................INVTVRLVPKLVRYTGT--E----RNGFKT---RGW--G--------
Q6CF00_YARLI/304-432SD.......NEQIYGDCLVTLRALPKLTEYTGC--Y----RNGINS---RSW--K--------
Q6CWM7_KLULA/160-284GAIPERE...IPF..AIKVDILMLPPLQGYASS--T----RNNITS---REW--T--------
Q8RWV9_ARATH/602-686.........PPPTMQELRTTIRVLPSQDYYTSK--L----RNNVRS---RAW--G--------
Q6FWF5_CANGA/150-281GEIPKDEHGLKPF..DLDVDILLLPRLQQYFSV--K----RYGITS---RHW--G--------
RXT3_YEAST/139-253GNLPLLE..GTPF..DLEVELLFLPTLQKYPSV--K----RFDITS---REW--G--------
Q59ZF1_CANAL/376-497NDDGTNLGIDKDVYGDLSVEILLLPNLPKYYGF--Y----QNGINS---RSW--L--------
YC57_SCHPO/220-301.........LKPVRKIAVVDLYILPPLVHYKGT--R----KNQIES---RSW--S--------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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