Sequence alignment for CL0542

PF00618

RPGF3_HUMAN/387-493TVMSGTPE..KIL-ELLLEAMGPDSSA.HDPTE.TFLSDFLLTHRVF-MPSA-QLCAALLHHF.................
GEFY_DICDI/1077-1209KVRSASLD..AMI-DLLTNH.RLS.......QP.DLVESFLLTYKTF-TSPL-AVLTKLIERYEET..............
GNDS_MOUSE/60-172TVKAGTLE..KLV-EHLVPAFQGS.......DL.SYVTVFLCTYRAF-TTTQ-QVLDLLFKRY.................
Q19852_CAEEL/87-187LIKAGTVE..RLV-ECLVGSDDMM.......DS.RHFNVFFATYRSF-TDSA-IVLDCLLRRY.................
RPGF1_CAEEL/519-629SVMAGKAE..KIL-EYVLET.RIDALGDDISELDVFVEDFILTHDAF-MPDN-TVCNFLKSYY.................
GEFS_DICDI/648-742SILKVTLN..QLV-LMLTSE.TSY.......DS.KFLKTFITTYQSF-ASPG-VLFTKLIERF.................
CDC25_CANAL/903-1007NIKGGSKE..ALV-SHLTHH.LSL.......DS.NFNAVFLLMFSSM-MSLG-ELISLLIARFN................
CDC25_YEAST/1120-1223KIRGGTKE..ALI-EHLTSH.ELV.......DA.AFNVTMLITFRSI-LTTR-EFFYALIYRYN................
GBPD_DICDI/29-131AIKSCSLA..KLI-EKLTSTKQLH.......TY..FSSAFFLTYRDF-TTPL-EIINLLISRY.................
GEFG_DICDI/1119-1220VQKLMNLN..QLV-DKLTSITVAT.......EI.SEVNACLATYRTF-ISTS-QLVEKLFQRY.................
Q6FQG1_CANGA/1120-1264NTNDLSDI..GLL-DFAYIKINMD.......NA.AYTETFFNTYKSF-TTTV-NVLEGLARRFIGAKSCA..........
Q21758_CAEEL/33-133AVLSGSRD..ALI-RRLVPTRDFC......PDE.SYIFSLLVNIRTF-ISPH-ELMQKIVQYC.................
GEFO_DICDI/405-502EVKYGSLN..KLI-ERLCLP.NCY.......DD.NYVNIFLLTYHSF-CSSK-KLLKKLIERFT................
Q6CQ00_KLULA/1000-1138KYNEGNGA..GLL-DYAIVKLCMD.......ND.LYTKTFFSTYKSF-TTTA-SLLENLAKRFIGAKSCA..........
GEFQ_DICDI/553-665EVIAGERD..KII-GLFTDISKVT.......GT.QFLEEFLFTYHYY-MTSV-DLLENLKGRF.................
GEFB_DICDI/1078-1179SIKYASLN..QLI-LKLTCE.SNT.......EL.RFTKTFITTYRSF-TTGD-IFLMKLIQRY.................
RGRF1_MOUSE/638-779QIRYASVE..RLL-ERLTDL.RFL.......SI.DFLNTFLHSYRVF-TNAM-VVLDKLINIYRKPMSAIPA........
RGRF2_HUMAN/638-787QIRYASVE..RLL-ERLTDL.RFL.......SI.DFLNTFLHTYRIF-TTAA-VVLGKLSDIYKRPFTSIP.........
Q9N5D3_CAEEL/659-794VIKCGTVL..KLI-ERLTYH.SYT.......DS.KYILTFLISYRSF-CTPN-DLFSLLLERFN................
Q6CUP1_KLULA/782-890NLAGISFR..ALV-FMITDEMRKS.......DD.NLLYTFLLNYKSF-GNSE-ELIELLISRFDSKSQ............
Q7PF82_ANOGA/481-588TVMSGTPQ..KML-EHLLET.RLGGQ...AGPNDPFLDDFLLTHIVF-MPTP-LLIDELAANY.................
STE6_SCHPO/492-600KIKTATLV..FII-NYLLRT.DID.......ST.FFTTIFLNTYASM-ISSS-DLFSILGAHFR................
LTE1_KLULA/40-144RILKCTLP..ALL-VQLSSPLDKV.......DY.SMLTDFFLVYRNF-MSSQ-KLLDLIQERFQWAID............
EFC25_SCHPO/593-700NVKGGTLP..ALV-HYLVQN.VHL.......NK.DFRHSFLLTYKTF-TTPQ-ELFTLLVILFH................
Q6FXB3_CANGA/683-791ELITATCR..GLV-FKLTDELDHP.......SS.FFVSTFLLNFRSF-MKSY-ELVTELINRFDLADM............
GEFE_DICDI/499-670IVKGGTIE..KLV-NRLIAK...........HDPDFTSAFLLTHKSF-TTSI-ELLDLLIEFYVNNKDSSSINSNSSSSS
GEFF_DICDI/676-780QIKAATFN..KLI-HYLAPKEKAF.......DP.NFLKVFLYTHSSF-TTSE-KLLKKLIQRY.................
RGL3_MOUSE/67-175ALRAARLE..RLV-HELVSGDREQ.......DP.GFVPAFLATHRAF-VPTA-RVLGFLLPPP.................
BEM2_ASHGO/980-1134QHNGQHSI..GLL-DFALISLIMD.......NE.LFAETFFNNYKSF-TTTL-CVLENLAKRFIGAKSSAISISL.....
Q5E9S7_BOVIN/20-120RLISGSLE..ALM-EHLVPTVDYY.......PDRTYIFTFLLSSRVF-IPPH-DLLARVGQLC.................
GEFD_DICDI/240-336IVKAATFD..RLV-EKLFDLSYGF.......KDPDYNYTVFHTYDYY-TTSV-ELLGKIVHYYR................
GEFP_DICDI/1105-1213EIKGGTTE..KLI-ELLYNS.EFI.......GS.DYFETFLLTYRSF-ASPK-RVMDVLTKTYNEN..............
Q5B8N8_EMENI/364-459NISAATPA..RIV-AQISSE.SFM.......DY.ELVSDFFLTFRPY-LSAS-SLLSLLLARLQ................
Q7KTU3_DROME/116-261RLHSGPLQ..SLI-AHMVPTHEYY......PDE.GFIFAFLLSARLF-VRPH-ELLAQISQTW.................
GEFM_DICDI/393-496VVVSGPKD..QLV-EYLCNK.NKL.......DF.SFVNSFILSFRYF-IEPE-ELFNHLMVKYETKVQT...........
Q5K6X7_CRYNJ/910-1013AVKAGTLR..ALI-VRLTSH.TIA.......DT.PFFQAFLLTFRSF-TNPA-ELFNHLQDRYY................
Q5BBF0_EMENI/809-915TLKCGTLA..GLV-EHLTRH.DKP.......DM.SFNSTFLLTYRSF-TTAS-ELFEMIMQRFN................
VKIND_HUMAN/1249-1348ILQAGTPL..GLM-AYLYSSDAFL.......E..GYVQQFLYTFRYF-CTPH-DFLHFLLDRINS...............
Q5K7Q6_CRYNJ/994-1100NMVGASLA..VLV-EKMTPHDGPV.......DS.SFSATFFYTFRLF-TTPV-DLLEAVQERWF................
Q6FVQ6_CANGA/813-919RMKGANKR..DLF-EYLFQS.SSL.......DM.PFAITMLITFRTI-FTST-EFIVNIIERFE................
BEM2_YEAST/1123-1270STRGLSDDNIGLL-DYAFVKLTMD.......ND.IFTETFFNTYKSF-TTTT-TVLENMAKRYVGAKSCS..........
GEFI_DICDI/429-527QVKAASLN..KLV-ILLTPE.NNH.......DL.EYTKTFLLMYQSF-TTPE-ILLQKLIQRY.................
SOS_DROME/640-768MIKGATLC..KLI-ERLTYH.IYA.......DP.TFVRTFLTTYRYF-CSPQ-QLLQLLVERFN................
LTE1_ASHGO/40-143QIMAADVT..ALV-AALTSPVDGV.......EY.ELFADFFLVYRNF-LEAR-RLLELLEARFDWSLG............
LTE1_YEAST/28-133PVNSADLP..ALI-VHLSSPLEGV.......DY.NASADFFLIYRNF-ITPQ-DLHDLLIYRFRWCIRE...........
Q5AGW7_CANAL/1086-1246IPKYATVD..RLI-DLLLLDSKYFHRD.VHLDLTEYRFVFLLNYNSF-MTTK-ELLDKLAHRFINSGNAV..........
Q6BZP3_YARLI/890-1019VVKAASLD..RLI-DILILGVGHFAPR.VKMDMDLYTLTFFATFRSF-CSPT-QLLDAFRRRFVGAQSG...........
Q5B8H1_EMENI/28-136SVRAGSLA..ALV-EHLTHP.NKL.......DA.SFNRIFLTTYTYF-TSGT-ELVQLLIRRYD................
Q6CRG2_KLULA/1092-1198HIKGGTRL..ALI-EHLTNH.KSI.......DA.FFNIVILTTFRSM-FSTA-EFLRYLFKRFD................
Q59Z60_CANAL/135-237LINHATIK..ALI-IQMTSP.EII.......DY.SLICDFFLTYRMF-SNSN-EIMNLLLTRLIWALQ............
Q6C3H8_YARLI/18-128QLLGGSPP..DIV-EYLTSP.HTL.......DY.TLMSDFFLTYRMF-MDAT-ELLGLLLGRLEWAIG............
C8VT82_EMENI/412-506...GFTFD..ELV-DRLVAPPISK.......QDSKFASIFLCLYRKF-AAPA-TLLNALINRF.................
F1LQ26_RAT/164-270TVMSGTPE..KIL-EHFLETIRLEPSL.NEATD.SVLNDFVMMHCVF-MPNT-QLCPALVAHYH................
G1S8Q7_NOMLE/104-208.IKAGTLE..KLV-ENLLTAFGDN.......DF.TYISIFLSTYRGF-ASTK-EVLELLLDRYG................
Q4PEE7_USTMA/916-1021QVTGATLK..ALV-EKMTPHDTMI.......EA.TFSTAFFLCFRMF-TSPQ-ELLETLVARFE................

PF14663

J9JUC3_ACYPI/803-906....WILE--LLI.SQT.....VD-------DNPVVSMAALDALDEA.CDYN.EYLKILIG.LRP..NI.........LQ
R9ABX2_WALI9/828-933.PNEWALD--LLI.TQL.....YD-------PAIDICELAVKYLEKV.CEST.EILELVVS.MMP..SL.........DH
E9HCD6_DAPPU/779-903.LAKWVIP--LLL.NQL.....ND-------KCRAVVIAAADILDEA.TDDP.ACIEVLIP.LQT..QFVQLIQDQEKQH
C8V3E3_EMENI/926-1031..ADWVIK--LLV.TQL.....YD-------PDVSVCQVAVKILEEA.CNQR.DYLEFVVK.CRP..SL.........DH
Q6BYE3_DEBHA/800-909ECEHFVIK--LLV.NQL.....YD-------LDQEISDKSIDLLYDCYLSNDINILNHIIS.LRP..SI.........VI
H9KJU8_APIME/521-634DAYRWAIT--LLS.ERL.....SD-------INKTIALTALEALHEA.CEEP.EYLEALLQ.QGG..QF..RDWDKWLEE
B0CVR4_LACBS/858-965NANAWTLR--LLL.TQL.....YD-------PAPEVCEMAVHFLEEA.CESK.EILQLVVD.MQP..TM.........DH
B4JIR2_DROGR/813-918NFEVWGIP--LII.QQT.....KD-------ADRSVVLAAMDVLEEA.CHDK.YYLEEIVS.LWP..NL.........KQ
E5SLW9_TRISP/89-197GYEDWGLK--LMT.DRL.....ND-------SSMEVVSVVVEALHSLMTIGVYKSSFVKLN.................ID
Q75D08_ASHGO/921-1028TLEEFMLN--LLV.AQL.....YD-------LSSEVVAVADQILYHY.CLSQSITLALKPA.IAA..SL.........NQ
C4R7Q2_PICPG/777-881EAQEFFIE--VLI.NQM.....YD-------PQENIANLAIQEVDNY.ATSK.AQIEKFVE.TQPEPSI...........
A8NF25_BRUMA/108-212DFSVWGIK--LLL.GQL.....AD-------PSAKVVRHALRLLHRW.IPHYLESVYLIKD......IC.........FD
U5HAE6_USTV1/885-989.AEEWQLQ--LLL.TQL.....YD-------PSTEVRELAVRVLEQA.CRVQ.QTLETVVQ.MRP..SL.........DH
J3PML9_PUCT1/765-871DAKTWSIR--LLL.TQL.....YD-------PSPEVCGLAVEILEEA.CAGSIEVLETVVK.MRP..SV.........EN
A2E0D9_TRIVA/576-669AFAANPCS--LKL.NRC.....LA-------LFCEVIESQEDCLKAA.SVDQ...............QM.........HQ
F4W8J8_ACREC/737-850DAVRWAMT--LLA.DRL.....SD-------SYTAVALAALEALHEA.CDET.EYLEALLQ.QGG..QS..RDWDKWLQH
I2H1R1_TETBL/1078-1185.LINYIME--MLT.RQL.....YD-------LNPRVVALADQALYEN.AISETEPENLISW.LRT..SL.........SQ
V2YFJ2_MONRO/857-964VASAWMLR--LLL.TQL.....YD-------PSAQVREVAVKYLEEA.CESK.GVLELVVE.MRP..TM.........DH
F4P3M7_BATDJ/648-751TFYEWGIP--LLV.TQL.....SD-------PTQEIVGAAVCILQRH.CIDH.RNIIAFVR.TKP..DI.........QQ
D8LPP5_ECTSI/653-760RSEEWCIE--MLV.AQV.....HG-------DDPAVARAALSVLEEA.TQDE.RCLRTLVL.AKP..DL.........IH
D6WZE9_TRICA/747-854NFADWGVR--CLV.KQL.....KD-------PSRSVFLAALNTLHEA.CEVE.SCLETLVK.LNP..DL.........GH
A5E135_LODEL/1100-1210DFESFCIE--MSV.NSL.....YD-------SNSEIVSRSIAQLYKYYESIGFDTIGDFAT.YRP..PV..........H
F6WEC9_CIOIN/759-866GFHHWGSE--LLT.TQL.....FD-------RSNEVTAEAIDILHEA.CYDK.QYLRAVVR.LRP..TL.........LH
J3KDP4_COCIM/927-1031...EWIIM--LLI.SQL.....YD-------PDVAVCQIAMKVLEEA.CNQR.DLLEYVVQ.CRP..SL.........DH
S8EQT7_FOMPI/894-999..NSWTLR--LLL.TQL.....YD-------PAIEVREVAVRFLEEA.CESP.DVLQSVVE.MQP..TL.........DH
C5DQU5_ZYGRC/956-1063.LRRYIVE--MLT.RQL.....YD-------LSPQVVAIADQALYEY.VVKNESSHKLGSS.LHT..SL.........NQ
G0PMH3_CAEBE/65-167MFSDWGIQ--LML.RQL.....AD-------ESSKVVRHTIRILSRW.LPEHPSRNLRKCE.................WS
Q6FQM9_CANGA/941-1050NVQHYKME--LLT.RQL.....YD-------LSPKVVAVADRALYEY.ILTGNESEESSGSTFKL..FL.........NQ
J7S621_KAZNA/979-1086.MKKFTVE--MLT.RQL.....YD-------ASPNVVATADQALYEC.IVDTDVHGEMNIS.FRT..FL.........DQ
A7TMV1_VANPO/947-1055SLQQYMLE--MLT.RQL.....FD-------LSPKVVAVADQSLYEHVVRDENTSTEVGTW.LRT..SL.........NQ
A2EA80_TRIVA/110-211........--PYF.KQLVSTFKQD-------QINQRISPILQLLYEV.VQDDPKATEYCAN.DKEVHSILCKYGPIGYSY
H2VXG0_CAEJA/87-188TFCDWGIQ--LLL.RQL.....AD-------ESSKVVRHSIRLLNRW.LPENPSRNLRKVE.................WS
C5DE78_LACTC/899-1007VLEKFLVE--LLV.RQL.....YD-------LSPKVIAAADKILYDY.CATQDWPPRVDIP.RHH..LL.........DQ
E4Y0W8_OIKDI/394-503.KDKW.LY--LQT.LSL.....VR-------QSPKQSDTALVAFQQF......VRIPKIAN.....YAL.........QE
A3LXW6_PICST/871-982ECELFVIR--LLV.NNL.....YD-------PSPEIVSKSIDILSDHYSTNKCKNLNYLID.LHP..SI.........QI
M7NVD2_PNEMU/825-931.SIEWAIS--LLV.TQL.....YD-------PCIEVCQMAVEVLEKA.CYDF.ENLQYTVK.LRP..AL.........EH
Q16UV7_AEDAE/700-806NFEVWGMP--LLL.KLV....DEC-------QAKCVQLAALEILEEA.CYER.TYLEELVN.VWP..NL.........ER
B3S2G4_TRIAD/728-835NFSKWGLE--LLV.TQL.....YD-------TNEEIAACALEITTEA.CEDK.TCLESIVK.LQP..AL.........LC
U9SZG8_RHIID/735-840KFNEWGIQ--LLI.TQL.....YD-------PAMEVCQMAVRVLEET.CNHK.ENIESLVM.LRP..SL.........DH
E6ZW77_SPORE/1100-1205..GDWTIG--LLL.TQL.....YD-------PSVDVRQLATKVVEEA.CTSS.HILEKVVS.MRP..TL.........DH
W1QEH2_OGAPD/786-894ECESFACR--LLV.GQL.....CD-------PEENIRQLSVELLTSF.AKDE.EKVLEIIK.YRP..SI.........GV
G7DSK3_MIXOS/1003-1107...EWIIR--CLL.LQL.....YD-------SSNEVRELVVDILYPA.CDSP.EILETIVE.LEP..SL.........DH
G0SYK2_RHOG2/890-997AAEEWQVG--LLV.QQL.....YD-------SASEVVHQAVKVLEKA.CEND.ETLEMVVG.MRP..AL.........DL
G4UNU8_NEUT9/912-1019SDSKWAIQ--LLV.TQL.....YD-------PDIEVCATAVKILEKA.CNTK.NNLEYIVE.CRP..AL.........DH
G0QKR2_ICHMG/29-137.FFEWGID--MLV.NKL....NNS-------DQIEIRQKALNVIKEV.VQEK.KYMEIFFS.KNP..NL.........QD
Q6CMH7_KLULA/873-982KLEAYFIQ--LTC.RQL.....YD-------LAPTVVAIADKILYDY.CSTNVHPTKILQSSIKN..CL.........DQ
K5VKD3_PHACS/897-1002.ANAWALR--LLL.TQL.....YD-------PDMVVQEVAVRYLEEA.CESL.NVLEMVVE.MHP..TL.........EH
C9SP12_VERA1/926-1031..WKWAIR--KLV.DQL.....YD-------PDVEVCRTAVKILEKS.CNKK.AYLEYVVQ.CRP..AM.........DH
Q7PSX6_ANOGA/826-936NFEVWGIQ--LML.KLVAAMLGDG-------QARCVQTAALELLEEA.CYER.AYLEELAH.FWP..RL.........DK
G0V941_NAUCC/930-1038DLQKFAMD--MLI.RQL.....YD-------LSPNVVAVADQALYEC.VVQSERSKEFAIS.FRT..IL.........NQ
I1CVE6_RHIO9/845-950..NDWLIR--LLV.TQL.....YD-------THMDVCQTAVNLLYEA.CENQ.ANLELLVK.YRP..SL.........GH
A4VDX0_TETTS/737-848DFSKWGIE--LIV.QKL....DIN-------QNEDIRMKALSVAKEV.TQEK.QYLMEFLK.KQP..CL.........QD
F1KRH6_ASCSU/839-943GFAEWGMS--LLL.AQL.....SD-------HSAKVVRHAIRLLHRW.MPFYPESISLLKN......VR.........LD
Q6C3B5_YARLI/788-895SSPHWAIS--LLV.GQL.....YD-------PDVEVCKLAVQLLQEY.CSVT.ENVPHVVK.CRP..AL.........DH
D3B1Y5_POLPA/11-118DFCHWGVD--FLV.QQL.....ND-------ADNKVAILALNVLDEA.CDDP.DCFETLIN.LKP..PL.........LK
M3JD48_CANMX/741-852ECESFVIK--ILV.ENL.....YD-------RGDDIVSKSIEILYNFYQDDDFVNLESLIK.FKP..SI.........NI
PIAA_DICDI/784-892DFSNWGVE--LLV.QQL.....ND-------VDAKVSALSLNVLDEA.CDDP.SCLEVLID.LKP..NL.........LK
H2B1N1_KAZAF/923-1030.LRRFKIE--MLT.RQL.....YD-------LSSNVVAIADRALYEC.ILEGYGSKEFSFS.LKT..FL.........DQ
F1QR10_DANRE/602-709FFSNWGME--LLV.TQL.....HD-------HNKTISMEALDILDEA.CEDK.ANLHALIH.MKP..AL.........SH
F4PXH0_DICFS/178-285DFSNWGVE--LLV.AQL.....ND-------PDTKVSQLALNVLDEA.CDDP.NGLDSLIH.LQP..PL.........LK
W5JMS9_ANODA/857-967NFEVWGVQ--LML.ELVASVQGEG-------QPRCMQLALIDLLEEA.SYER.VYLEELTH.CWP..RL.........DQ
A7SRE9_NEMVE/663-770FFNNWGME--FLV.TQL.....YD-------TETQVANEAADVLDEA.CEDE.ANLQYLVQ.LRP..VL.........LH
X6NW59_RETFI/156-269GYDQWSID--VLG.IML.....NK-------GNQELALTALKVLEKINVSQGNAKARSYLE......NL...VKTKPTDQ
E0VAL0_PEDHC/696-799NFSQWGLD--LLI.GQI.....YD-------ENKVIANASINILHEL.SYD.....QSLIS.IRP..AL.........LH
G4TRF3_PIRID/978-1085QSNVWMLR--LLL.TQL.....YD-------PAMEVRELAVRFLEEA.CETQ.DTLNVVVD.MQP..TL.........DH
K1PHU1_CRAGI/3475-3582GFSSWGME--LLV.NQL.....YD-------QSNQVAQAALHVLEEA.CDIQ.PCLNSVIK.LRP..QC.........LH
H3DZM0_PRIPA/58-162QFADWGVR--MMI.GQI.....GD-------ASVKVVRHAVRLLHTW.LPLHPSSLPLLRA......VP.........LH
A8WTI5_CAEBR/102-204MFSDWGIQ--LML.RQL.....AD-------ESSKVVRHTLRILNRW.LPEHPSRNLRKVE.................WS
B7PHW3_IXOSC/733-837DFRKWAME--LLV.TQL.....YD-------KSRATLSLGVSVV..L.CDQ..ENLEALIA.LRP..AL.........LC
G1XJT2_ARTOA/962-1069ETSQWAIR--LLV.TQL.....YD-------PDVEVCKTAVKILEEA.CNAR.TSLEYVVQ.CRP..AL.........DH
E9CA69_CAPO3/787-894AFAQWGIE--LLI.AQL.....YD-------LDLEVCYKAVEVLDEC.CDDE.SLLNSLVL.KRP..AL.........LH
Q5K7Q2_CRYNJ/992-1095VLVDWGLQ--LMI.TQL.....YD-------TAMEVCDVAVMYLEEA.CTDP.MWLEKVVQ.LRP..TL.........EH
J8LPE6_SACAR/977-1084KLQQFKME--MLT.RQL.....YD-------LSPSVVAVADQALYEC.IVAGNGSEELGTS.FRM..FL.........NQ
G8JSJ3_ERECY/925-1031KLEEFMLN--LLV.GQL.....YD-------LSSDVVAIADRILYHY.CIKQDLSLGLRPA.VTS..CL.........QQ
G0QUZ5_ICHMG/441-548DFFQYGIE--ILI.QKM.....DS-------PTRELREKALSVIYEV.IKDT.DQMKQFLN.LNP..NL.........TD
G0W3E1_NAUDC/926-1034KLRQFKME--MLT.RQL.....YD-------LSPNVVAIADEALYEC.IVDSDKSKEFSIS.FKT..FL.........NQ
A0EHS6_PARTE/758-868DFNIWAID--LLI.NCL......K-------KTDDIGLKALSVIEEV.TQDI.ENANRFLE.KVDIHRL.........LQ
G8ZRB4_TORDC/940-1048NLQRYVMD--MLT.RQL.....YD-------LSPKVVAAADQSLYDC.MMVDECSQEIISS.LKT..SL.........KQ
C3ZJ41_BRAFL/749-856FFNQWGVE--FLV.TQL.....YD-------KSKVVAMEAIDILDEA.CEEE.ANLHALVD.MRP..SL.........LH
M5E6L0_MALS4/714-818.TQSWAMS--LLL.AQL.....HD-------VAQSVRALARVRLQAA.CHHP.AMAQCAMR.QGPPTDL...........
G3AJX3_SPAPN/875-983ECESFIIK--ILVTSNL.....YD-------SNHDIAINTVDLLYSFYSDNDFANLNTLVG.LSP..SI.........SV
T1KEM6_TETUR/667-774DFRKWALE--LLT.QQL.....SD-------ESQAVVLAAIDILDEA.CDSI.ENLEALIS.LQP..NL.........LR
M5BUI9_THACB/547-654KANEWMLR--LLL.TQL.....YD-------PVSEVCEKAILYLQEA.CEDM.SILEAVVQ.MQP..IL.........DH
M2S0T8_COCSN/908-1015GVAEWAIR--LLV.TQL.....YD-------PDVEVCEVAIKILEEA.CNQK.ESLEFVVK.CRP..AL.........DH
K5WVI4_AGABU/760-865..NAWTMR--LLL.TQL.....YD-------PAPEITEVAVQFLEEV.CESK.EFLQMVVE.LQP..AM.........SH

PF00618

RPGF3_HUMAN/387-493...........H.VEPAGG.SEQ...............................ERSTYV....................
GEFY_DICDI/1077-1209.........DNI.NNNNNN.NND.DLIISTRTTATITNEDEDNSNSNSNSNKTNKNSSRT....................
GNDS_MOUSE/60-172...........G.RCDALT.ASS.RYGCI..................LPYSSEDGGPQDQ....................
Q19852_CAEEL/87-187...........E.TLENEV.NGS................................TSALL....................
RPGF1_CAEEL/519-629............FRTPYRA.TRD............................SITDSCTEE....................
GEFS_DICDI/648-742...........Y.VPEWYS.TVP...............................TKIST.....................
CDC25_CANAL/903-1007...........I.EPPEGL.SYE..EY.......................NLWVSKKRNP....................
CDC25_YEAST/1120-1223...........L.YPPEGL.SYD..DY.......................NIWIEKKSNP....................
GBPD_DICDI/29-131...........T.GPPPDS.SKD..SL.......................RLFEIEVDI.....................
GEFG_DICDI/1119-1220.............HIPRAS.NIK..SI.......................LDWKQRIETP....................
Q6FQG1_CANGA/1120-1264.....LSIEKII.GNENLD.SLK..DETLKSKLS.........QLNAKKFPLWDLNVNKNETVN................
Q21758_CAEEL/33-133...........M.FAQNAD.SHN..F.........................A........KE..................
GEFO_DICDI/405-502...........I.PEDLE..AHG..L.........................TLASIHE......................
Q6CQ00_KLULA/1000-1138.....VSIERLV.K..DDS.RKK..ATDLSGT.............TNNKFLCWDSASSEFGKEH................
GEFQ_DICDI/553-665...........N.NPLMDQ.AAQ..SISILE...............ENHDKVKIEQLSTH....................
GEFB_DICDI/1078-1179...........F.TPNLKN.IVP..Y.........................QFVQKIQIP....................
RGRF1_MOUSE/638-779...RSLELLFSS.SHNAKL.LYG..DAPKSPRAS.........RKFSSPPPLAIGT........................
RGRF2_HUMAN/638-787....VRSLELFFATSQNNRGEHL..VDGKSPRLC.........RKFSSPPPLAVSRTSSP....................
Q9N5D3_CAEEL/659-794...........I.PTPKKL.QQP..KQGGGP..............LAGRYDTVQSHGLSAISSSSCINPLC...EQKFRK
Q6CUP1_KLULA/782-890......AIKYTF.GGKNGT.FSS............................L..ASRVRS....................
Q7PF82_ANOGA/481-588...........H.ADADID.LRQ............................ASEEDQEYF....................
STE6_SCHPO/492-600...........F.ICSLNF.GKI............................SFISHEFYR....................
LTE1_KLULA/40-144.......LRQSD.PSSQEK.ITS.........................................................
EFC25_SCHPO/593-700...........E.LPPPGL.DAT..AY.......................SSWEKGDNFV....................
Q6FXB3_CANGA/683-791......ENKLRD.NKPKGK.YST............................T..ASKLKN....................
GEFE_DICDI/499-670SSAVASSSFSNI.NCNISD.LSSSTSSTNSLLIN........SITNSPIINSNNQNNQNNNNNNNNNNNNNNNQLEINGD
GEFF_DICDI/676-780...........Q.VPNSNA.NEP............................KYKSEVVEP....................
RGL3_MOUSE/67-175.............PPPPPP.PAG.............................VDSKRTEGQ...................
BEM2_ASHGO/980-1134INKLRNSESSRQ.IPPSTT.SNQ..FSASGIFKP.........SYDELKFPVWDLKVTSVEGCPL...............
Q5E9S7_BOVIN/20-120...........V.EQRQQL.EAG...............................SEKAKL....................
GEFD_DICDI/240-336...........I.ACTLTT.KLQ.........................................................
GEFP_DICDI/1105-1213........YSVEGNATDDV.EKR..LE......................LDQFNKQRKD.....................
Q5B8N8_EMENI/364-459..........WA.INRLQE.DGR............................I............................
Q7KTU3_DROME/116-261...........E.HQQQDV.GTG..GDVVDDAGQ.........GPGRTMMVSINSASPLTQRKGSAAAASHSSELEPRLQ
GEFM_DICDI/393-496......TSSIKV.SKQFEE.IQD............................R............................
Q5K6X7_CRYNJ/910-1013...........L.PPPPEL.NRE..QY.......................EEWRNKKKWY....................
Q5BBF0_EMENI/809-915...........I.QPPFGL.NAD..EM.......................QMWVDRKQKP....................
VKIND_HUMAN/1249-1348.........TLT.RAHQDP.TST............................F............................
Q5K7Q6_CRYNJ/994-1100...........I.SPPEEL.LLS..EKD.....................EAVWREAKVLP....................
Q6FVQ6_CANGA/813-919...........E.APPENL.SYE..EY.......................NDWIEKKYLP....................
BEM2_YEAST/1123-1270.....VSISKIL.DRSDDS.KMKINEDTNLVSS..........SLYDQNFPVWDMKVTDDENIN................
GEFI_DICDI/429-527...........H.VPQKAG.QSV..A.........................EWRQRSTH.....................
SOS_DROME/640-768...........I.PDPSLV.YQD..TGTAGAGGM.........GGVGGDKEHKNSHREDWKRYRK...............
LTE1_ASHGO/40-143.......EIGAG.RAKARV.VGE.........................................................
LTE1_YEAST/28-133......ITTNAA.KAKRRR.IGE............................V............................
Q5AGW7_CANAL/1086-1246....ISVMKKNYLLKKLNH.ESDKTKMEPNFNQG........NPQLAMNFPNWNLDTAVDLNELGD.............V
Q6BZP3_YARLI/890-1019......STSLTM.PRTFDQ.KFP............................DWDSTHIPEKQPDY...............
Q5B8H1_EMENI/28-136...........C.APPVNL.NPM..KA.......................AEWSSQAKPL....................
Q6CRG2_KLULA/1092-1198...........L.SPPEGL.SYE..EY.......................NVWVDRKQKP....................
Q59Z60_CANAL/135-237.......YLNSV.SEDNIK.IGK............................L............................
Q6C3H8_YARLI/18-128.......VQNEV.NKALRQ.SQN............................ARNSEKGRD....................
C8VT82_EMENI/412-506...........E.RNEKDI.TDQ................................LTRIA....................
F1LQ26_RAT/164-270...........A.QPSQGT.EQE................................RMDYA....................
G1S8Q7_NOMLE/104-208...........N.LTSPNC.EED.GS.........................QSSSESKMV....................
Q4PEE7_USTMA/916-1021...........M.SPPAEV.PMS..EAD.....................MVRWNDKKLVP....................

PF14663

J9JUC3_ACYPI/803-906L.GD..RGLLLL-VRFLSD-TGG---------------------------------------------------------
R9ABX2_WALI9/828-933L.GE..TGHPLM-LRFLST-SVG---------------------------------------------------------
E9HCD6_DAPPU/779-903L.DS..RARLLL-IKTLSI-MSG---------------------------------------------------------
C8V3E3_EMENI/926-1031L.GE..IGAPLL-LRFLST-SVG---------------------------------------------------------
Q6BYE3_DEBHA/800-909L.SKHASGKMLL-MNFMKT-SIG---------------------------------------------------------
H9KJU8_APIME/521-634L.GD..KGYLLK-IRLYSL-HQG---------------------------------------------------------
B0CVR4_LACBS/858-965L.GE..IGHPLL-LKFMST-PMG---------------------------------------------------------
B4JIR2_DROGR/813-918L.GD..VGRLLM-SRFYSL-SRG---------------------------------------------------------
E5SLW9_TRISP/89-197LSKIDDAGVLLN-TYRYSF-DEA---------------------------------------------------------
Q75D08_ASHGO/921-1028L...VFIGSPIL-FELMAS-SAG---------------------------------------------------------
C4R7Q2_PICPG/777-881LFKM..KADSLL-RKVFSI-SKG---------------------------------------------------------
A8NF25_BRUMA/108-212IFGD..AGILLK-TYLFSN-ESY---------------------------------------------------------
U5HAE6_USTV1/885-989L.GS..IGADLL-TRFLST-SIG---------------------------------------------------------
J3PML9_PUCT1/765-871L.GD..VGAPLL-LRFLST-SVG---------------------------------------------------------
A2E0D9_TRIVA/576-669VLKK..ANRRIY-SMLLSQ-KDS---------------------------------------------------------
F4W8J8_ACREC/737-850L.GD..KGYLLK-IRLYSL-QQG---------------------------------------------------------
I2H1R1_TETBL/1078-1185M...VFIRSPIL-FELLST-SYG---------------------------------------------------------
V2YFJ2_MONRO/857-964L.GD..IGNSLL-LKFMST-PTG---------------------------------------------------------
F4P3M7_BATDJ/648-751L...TVLGNTLL-IQSLAV-PAG---------------------------------------------------------
D8LPP5_ECTSI/653-760KPGA....NDLL-MRFLSI-PEG---------------------------------------------------------
D6WZE9_TRICA/747-854L.GE..KGSLLA-LRLLSI-TSG---------------------------------------------------------
A5E135_LODEL/1100-1210ILANDELGADLL-IKCLST-TRG---------------------------------------------------------
F6WEC9_CIOIN/759-866L.GD..RGSLLV-CRFISD-PKG---------------------------------------------------------
J3KDP4_COCIM/927-1031L.GE..IGASLL-LRFLSS-SVG---------------------------------------------------------
S8EQT7_FOMPI/894-999L.GE..MGHPLM-LKFMST-PMG---------------------------------------------------------
C5DQU5_ZYGRC/956-1063L...VFIRSPII-FELLGT-KNG---------------------------------------------------------
G0PMH3_CAEBE/65-167VFGE..AGDLLK-AHVYAL-EFE---------------------------------------------------------
Q6FQM9_CANGA/941-1050M...VFIRSPIL-FEILGR-PYG---------------------------------------------------------
J7S621_KAZNA/979-1086M...VFIQSPVI-FELLSS-PYG---------------------------------------------------------
A7TMV1_VANPO/947-1055M...VFISSPIL-FELMSS-KYG---------------------------------------------------------
A2EA80_TRIVA/110-211I...........-...FST-PTA---------------------------------------------------------
H2VXG0_CAEJA/87-188VFGE..AGDLLK-AHIYAI-ESE---------------------------------------------------------
C5DE78_LACTC/899-1007L...MFIRSPIL-LEFLKT-PAG---------------------------------------------------------
E4Y0W8_OIKDI/394-503LGMIMEFDLCLR-QKILCV-LVE---------------------------------------------------------
A3LXW6_PICST/871-982L.SRTIKGRNLL-INFLNI-PSG---------------------------------------------------------
M7NVD2_PNEMU/825-931L.GS..IGAPLR-LRFLAS-STG---------------------------------------------------------
Q16UV7_AEDAE/700-806V.SD..HGKLVM-MKFYSI-PRG---------------------------------------------------------
B3S2G4_TRIAD/728-835L.GH..SGYCLM-LRFCSI-ESG---------------------------------------------------------
U9SZG8_RHIID/735-840L.GE..VGNPLL-LRFLST-SIG---------------------------------------------------------
E6ZW77_SPORE/1100-1205L.GE..LGHPLL-LKFLST-SVG---------------------------------------------------------
W1QEH2_OGAPD/786-894LETP..SGINLM-LKILAT-GPG---------------------------------------------------------
G7DSK3_MIXOS/1003-1107L.GE..VGIPLL-TRFMST-TIG---------------------------------------------------------
G0SYK2_RHOG2/890-997L.GE..VGVPLL-IKFLST-SAG---------------------------------------------------------
G4UNU8_NEUT9/912-1019L.GE..IGAPLL-LRFLST-SIG---------------------------------------------------------
G0QKR2_ICHMG/29-137LCDE...SDPFL-ITLLQT-EEG---------------------------------------------------------
Q6CMH7_KLULA/873-982L...IFIGSPTL-LKLMET-SEG---------------------------------------------------------
K5VKD3_PHACS/897-1002L.GD..IGHPLL-LKFMST-TLG---------------------------------------------------------
C9SP12_VERA1/926-1031L.GE..MSAPLL-LRFLSS-SSG---------------------------------------------------------
Q7PSX6_ANOGA/826-936L.GH..RGKMVM-MRFYSI-PRG---------------------------------------------------------
G0V941_NAUCC/930-1038M...VFIRSPIL-FELLSR-SYG---------------------------------------------------------
I1CVE6_RHIO9/845-950L.GE..IGNPLL-LRFLST-STG---------------------------------------------------------
A4VDX0_TETTS/737-848LGKE...GDQFL-MTLLSS-DLG---------------------------------------------------------
F1KRH6_ASCSU/839-943ALGD..AGIMLK-THLFAN-EDY---------------------------------------------------------
Q6C3B5_YARLI/788-895L.GA..VGAPLL-LRFLCT-SSG---------------------------------------------------------
D3B1Y5_POLPA/11-118L.GK..PGKSLL-LRFLSR-TNG---------------------------------------------------------
M3JD48_CANMX/741-852L.KKYPLGSKLL-LNFLKF-PVG---------------------------------------------------------
PIAA_DICDI/784-892L.GK..PGKSLL-LRFLSS-PKG---------------------------------------------------------
H2B1N1_KAZAF/923-1030M...VFIRSPIL-FELLSK-SYG---------------------------------------------------------
F1QR10_DANRE/602-709L.GD..KGLLLL-LRFLSI-PKG---------------------------------------------------------
F4PXH0_DICFS/178-285L.GK..NGKSLM-LRFLSR-KSG---------------------------------------------------------
W5JMS9_ANODA/857-967L.GD..RGKMIM-MRFYSI-PRG---------------------------------------------------------
A7SRE9_NEMVE/663-770L.GE..RGIRLM-TRFVAV-ERG---------------------------------------------------------
X6NW59_RETFI/156-269MVGN..YGQFLF-AKLLST-SSG---------------------------------------------------------
E0VAL0_PEDHC/696-799L.GD..KGHLLL-IRFLST-VTG---------------------------------------------------------
G4TRF3_PIRID/978-1085L.GE..LGHPLL-LRFMST-AAG---------------------------------------------------------
K1PHU1_CRAGI/3475-3582L.GE..RGVLLL-CRFMST-AKG---------------------------------------------------------
H3DZM0_PRIPA/58-162TLGD..AGVLLR-VHLFSC-ETE---------------------------------------------------------
A8WTI5_CAEBR/102-204LFGE..AGDLLK-AHIFAM-ESE---------------------------------------------------------
B7PHW3_IXOSC/733-837L.GD..RGLLLQ-IRFLSL-PSG---------------------------------------------------------
G1XJT2_ARTOA/962-1069L.GE..IGAPLL-LRFLST-SVG---------------------------------------------------------
E9CA69_CAPO3/787-894L.GE..PGKAIL-TRLLST-FRG---------------------------------------------------------
Q5K7Q2_CRYNJ/992-1095L.GD..VGHPLF-MRFVST-SVG---------------------------------------------------------
J8LPE6_SACAR/977-1084M...VFIRSPIL-FELLSR-PYG---------------------------------------------------------
G8JSJ3_ERECY/925-1031L...VFIGSPIL-FDLLAG-TTG---------------------------------------------------------
G0QUZ5_ICHMG/441-548LCEN...DNPLL-YIIMKT-SQG---------------------------------------------------------
G0W3E1_NAUDC/926-1034M...VFIRSPIL-FELLSK-PYG---------------------------------------------------------
A0EHS6_PARTE/758-868LCQK..CESQLI-IMLLSH-KKG---------------------------------------------------------
G8ZRB4_TORDC/940-1048M...VFIRSPLL-FELLGT-PHG---------------------------------------------------------
C3ZJ41_BRAFL/749-856L.GD..KGAMLL-IRFLSI-SKG---------------------------------------------------------
M5E6L0_MALS4/714-818....LVSEDTLA-LQCLAV-PLG---------------------------------------------------------
G3AJX3_SPAPN/875-983L.SQFKNGRLLL-IHFMKI-PIG---------------------------------------------------------
T1KEM6_TETUR/667-774V.GD..RGLLLL-IRYLSI-PNG---------------------------------------------------------
M5BUI9_THACB/547-654L.GE..VGHPLL-LKFMST-QIG---------------------------------------------------------
M2S0T8_COCSN/908-1015L.GE..IGAPLL-LRFLST-SVG---------------------------------------------------------
K5WVI4_AGABU/760-865L.GD..IGDALL-LKFMST-SMG---------------------------------------------------------

PF00618

RPGF3_HUMAN/387-493.....CNKR---QQ.---------.-.ILRLVSQWVA--LYGS...M......LHTDPV.............ATSFLQKL
GEFY_DICDI/1077-1209.....IKL.---.G.---------.-.VLSIIKCWVD--RHHY...D......FERNKA.............LLSAIVAF
GNDS_MOUSE/60-172.....LKN.---.A.---------.-.ISSILGTWLD--QYSE...D......FCQPPDF...........PCLKQLVAY
Q19852_CAEEL/87-187.....VQN.---.S.---------.-.IRQIVMCWLE--TYPE...D......FYDSDKD..........FAMLSSLLDF
RPGF1_CAEEL/519-629.....VRCK---RR.---------.-.VVQFVYVWCS--LLRV...N......FFLNPV.............TNSFVEEL
GEFS_DICDI/648-742.....IQQ.---.K.---------.-.VIVVLKYWIE--NQSS...D......FDQD...............VIDQIYFF
CDC25_CANAL/903-1007.....IRL.---.R.---------.-.VINIMKLLLE--KNWS..MS......YYNEP..............VLRRWLTF
CDC25_YEAST/1120-1223.....IKC.---.R.---------.-.VVNIMRTFLT--QYWT..RN......YYEP...............GIPLILNF
GBPD_DICDI/29-131.....VQA.---.N.---------.-.VLSIFRTLIG--TLIQ..VD......FDTPK..............LSSSIIEF
GEFG_DICDI/1119-1220.....IQV.---.K.---------.-.VCKVFKKLID--DHFD...D......FNGT...............IIELFKVF
Q6FQG1_CANGA/1120-1264.LGFLAKVQ---IG.---------.-.AMEAIYYLVK--HHYN...D......FTDDMNC..........HTTMLDIVKI
Q21758_CAEEL/33-133...GRGRMF---AH.---------.-.ILRLCSEWAT--NIPY...D......FKTEY..............MRTRLNEL
GEFO_DICDI/405-502.....IHM.---.K.---------.-.IRSVLVKWIN--EYSP...K......FDQD...............TIHLFQNF
Q6CQ00_KLULA/1000-1138.YLHAAKIQ---IG.---------.-.TAEALFYLIN--EHYS...D......FNDDMHN..........NKLLLDIIKI
GEFQ_DICDI/553-665.....IRL.---.R.---------.-.VINVIKKWIE--NHGY...A......FATDIN.............LYQMLVDF
GEFB_DICDI/1078-1179.....IQL.---.R.---------.-.VLNVLRLWIE--QYPS...D......FQQPPQ.............ITTQSTQP
RGRF1_MOUSE/638-779.....SSPS---RR.---------.-.RKLSLNIPII--TGGKA.LELASLGCSSDSYA............NIHSPISPF
RGRF2_HUMAN/638-787.....VRA.---.R.---------.-.KLSLTS.PLN--SKIGALDL......TTSSSPTTTTQSPAASPPPHTGQIPLD
Q9N5D3_CAEEL/659-794EFQQPIQL.---.R.---------.-.VLSVINQWVK--LHWY...D......FQCDPV.............LLDALELF
Q6CUP1_KLULA/782-890.....RRR.---.L.---------.-.VCKVIQLWME--SFWD..........YGDDYK.............LIALLINF
Q7PF82_ANOGA/481-588.....LTSK---RR.---------.-.VVQFIQRWVL--AVRH...A......VFDDPL.............AVEFIEEL
STE6_SCHPO/492-600.....VSK.---.R.---------.-.FLDILLIWFE--SYLVEELDNSKSIFFLFK...............IYKVFEVF
LTE1_KLULA/40-144.....EVIL---VR.---------.-.MFVLVRHWLS--NYFA..QD......FVVDTS.............LRRQFLQF
EFC25_SCHPO/593-700.....TKK.---.N.---------.-.VCTVMNLWVQ--KYFFEDLK......ARNTLY.............LISEMRTF
Q6FXB3_CANGA/683-791.....RRR.---.L.---------.-.ICSVFNEWME--SYWD..........YNTDFE.............CISTMINF
GEFE_DICDI/499-670KKKKAIRL.---.K.---------.-.ITNVIKSWVD--KHYY...D......FSEDKQ.............LTLKLDQF
GEFF_DICDI/676-780.....VRQ.---.R.---------.-.VVDVLKYWVD--KCPW...D......FNAGPTS..........SVLVATLNNF
RGL3_MOUSE/67-175....DLNFS---KNL---------R-AVVSVLGSWLR--NHPQ...D......FRDPPDH...........QNLGNVRIF
BEM2_ASHGO/980-1134DYLAKIQI.---.G.---------.-.VLESLYHLIR--EHYA...D......FTDDLAN..........NKTFLDILKI
Q5E9S7_BOVIN/20-120.....KSFS---AK.---------.-.IVQLLKEWTE--AFPF...D......FQDEK..............AMAELKAI
GEFD_DICDI/240-336.....MEVS---IT.---------.-.ILSVAMFWMK--IHHN...H......LMTDLQ.............FLQKLKIF
GEFP_DICDI/1105-1213.....THL.---.K.---------.-.ICNFLKRWVE--KHFY...D......FDQD...............LLQEFNTF
Q5B8N8_EMENI/364-459.....IRI.---.R.---------.-.TFAALRHWIL--NYFV..DD......FVPDFK.............LRAHFCET
Q7KTU3_DROME/116-261QRTNTQRSA---QH.---------.-.CIRLLSEWIE--IFPY...D......FRDER..............LMQQVRIL
GEFM_DICDI/393-496.....IRQ.---.N.---------.-.ILIIISVWVD--CNYS...D......FEDNLS.............LHKRLFKL
Q5K6X7_CRYNJ/910-1013.....IQL.---.R.---------.-.VVNALRQWLE--KHFI...R......ATDDA..............VLSKVEEL
Q5BBF0_EMENI/809-915.....IRF.---.R.---------.-.VVNILKTWFE--NYWM...E......PNDESHM...........QLLERAHSF
VKIND_HUMAN/1249-1348.....TKIY---RR.---------.-.SLCVLQAWVE--DCYA..VD......FPRNSG.............LLGKLEDF
Q5K7Q6_CRYNJ/994-1100.....IRI.---.R.---------.-.IFNFLRTWLE--FHWQ..........PEVDNV.............ILNDLEKF
Q6FVQ6_CANGA/813-919.....NKE.---.R.---------.-.VIYLLWKLFT--FFWN...E.....RYMDFPV............ALLENCIKT
BEM2_YEAST/1123-1270.LIYMAKIQ---IG.---------.-.AAEAILHLVK--NHYS...D......FTDDLCN..........NSTLLDIIKI
GEFI_DICDI/429-527.....IQL.---.R.---------.-.VLNVLKTWIK--DYFS...D......FSEK...............LILAIKSL
SOS_DROME/640-768EYVQPVQF.---.R.---------.-.VLNVLRHWVD--HHFY...D......FEKDPM.............LLEKLLNF
LTE1_ASHGO/40-143.....ITL.---VR.---------.-.TFVLLRHWVI--NYFA..QD......FLPDVA.............LRERFLAF
LTE1_YEAST/28-133.....ALV.---.R.---------.-.TFVLLRHSIL--NYFV..QD......FLPNIT.............LRLRLIEF
Q5AGW7_CANAL/1086-1246DYELLLKIQ---IN.---------.-.ILKVLIVLIN--NFYS...N......FSLDLAN..........KNILIKLLKL
Q6BZP3_YARLI/890-1019RLMAQIQI.---.G.---------.-.ILEACFLWVS--QYFI...D......FVNEYA.............VRELFLDF
Q5B8H1_EMENI/28-136.....IQV.---.R.---------.-.VLDTLNQWLE--NFWT..........WNEPKGPE........THENLLNLQSF
Q6CRG2_KLULA/1092-1198.....IRI.---.R.---------.-.VINIIKAWLT--DYWN...D.....CYYEDSQ............DSLDELNTV
Q59Z60_CANAL/135-237.....VLV.---.R.---------.-.TFVVLRHWII--NYFV..DD......FNNNNE.............LCDYFTNT
Q6C3H8_YARLI/18-128.....VCV.---.R.---------.-.TFVVLRHWVL--NFFA..DD......FVPSHT.............IRSMFADT
C8VT82_EMENI/412-506.....DQL.---.R.---------.-.LLSVIAQWVS--EYPG...D......LAYPK..............TRKRIVDF
F1LQ26_RAT/164-270.....LNNK---RR.---------.-.VIRLVLQWAA--MYGD...L......LQEDDV.............AMAFLEEF
G1S8Q7_NOMLE/104-208.....IRN.---.A.---------.-.IASILRAWLD--QCAE...D......FREPPHF...........PCLQKLLD.
Q4PEE7_USTMA/916-1021.....VRL.---.R.---------.-.VLNLFKSWLE--NNWN...P.......TTDRV.............ILQQLIS.

PF14663

J9JUC3_ACYPI/803-906-----YKYL...SES.........S.FVSNQLHNWGT..HFNF---R------YVLIVEG------------ELHDQLTL
R9ABX2_WALI9/828-933-----FKYL...QQS.........D.YIDREIDDWFH..ERNA---H------YVVLIEV------------YISHALG.
E9HCD6_DAPPU/779-903-----FKHW...QETFVETENTKIS.LVQQELDQWIS..HLNV---R------YVQLVES------------DLADGLTQ
C8V3E3_EMENI/926-1031-----YHYL...DGL.........D.YITQEMDDWFL..GRND---A------YVSLVEA------------ALSRAYVD
Q6BYE3_DEBHA/800-909-----FKFL...EDS.........G.FIDAEFDKWIN..LIGF---E------YVKKIEL------------LIQRRF..
H9KJU8_APIME/521-634-----FTTL...SSP.............AEELEKWISPGGFAE---R------YVGLIEG------------EIHDSLTR
B0CVR4_LACBS/858-965-----FRYL...YDA.........G.YIDREMDMWFN..ERNI---Y------YVVQVEV------------FLAKVFNT
B4JIR2_DROGR/813-918-----...L...NSS.........EAHIEDEIKYWRN..GYNK---R------YVLLVEA------------DTHASLTL
E5SLW9_TRISP/89-197-----VRAS...DEH.........LKACIVEVNYWTY..SFCE---Q------YAAMVEE------------VITEIQGN
Q75D08_ASHGO/921-1028-----FKLL...NNI.........S.YIEKERLLWLE..RKNR---E------YVHIVEE------------FLEKELR.
C4R7Q2_PICPG/777-881-----YNYL...HDL.........G.FIDDSLKNWIT..KESL---S------FVGRVEE------------ILKH....
A8NF25_BRUMA/108-212-----VK.....DNS.........R.DVLATLDYWKR..KFNM---R------YVEIVDE------------DVRVALLD
U5HAE6_USTV1/885-989-----VAYL...HEI.........E.FIDRELEDWYA..ERNL---T------YVIELEL------------LMAQAL..
J3PML9_PUCT1/765-871-----ARYL...NEI.........E.WTEREMDDWFQ..ERNR---D------YVIQLEV------------YLSKLL..
A2E0D9_TRIVA/576-669-----LSFV.................NLEEEIDWWIE..KGNK---E------YVEIYDE------------AISCSFND
F4W8J8_ACREC/737-850-----FASL...AAP.............SEELEKWIGPGGFAE---R------YVGLVEG------------EIHDALTY
I2H1R1_TETBL/1078-1185-----FQLL...DEV.........D.FIESERISWIK..RKNE---E------YVNIIED------------FLNGSRND
V2YFJ2_MONRO/857-964-----FRYL...FDS.........G.YIDREIDIWYS..ERNL---Y------YVVQVEV------------FLAHVFSN
F4P3M7_BATDJ/648-751-----FKYL...FES.........G.YLDTETDYWFE..YGNV---Q------FVTHAEL------------SISE....
D8LPP5_ECTSI/653-760-----IVYL...EEH.........G.WVEQMVREWKD.SGRTT---T------YADSVDM------------KWKTHVND
D6WZE9_TRICA/747-854-----FQLL...NKN.........D.FVVNEIKRWDE..YFIY---R------YIKLVEG------------ETSDALTL
A5E135_LODEL/1100-1210-----LVYL...LKR.........G.FITFELGKWMQ..IKNF---R------YARKLDY------------LIRQQFF.
F6WEC9_CIOIN/759-866-----FEYL...SQN.........H.YLTRELGRWRS..QYNE---K------YVLYVEE------------LLKLSLTS
J3KDP4_COCIM/927-1031-----YHYL...DGL.........D.FVHQEMDDWFL..GRND---A------YVGLVEA------------SLCRAYLD
S8EQT7_FOMPI/894-999-----FRFL...YSA.........N.YIDREMDIWFH..ERNL---Q------YVVYIEV------------FLAKIFSS
C5DQU5_ZYGRC/956-1063-----FQLL...NEI.........N.FVQEERKSWLA..TKNK---E------YVFLVEN------------FLDYNQHG
G0PMH3_CAEBE/65-167-----CA.....SDE.........D.EVRDVIRFWMT..DFNK---K------YLQIIDE------------EMKEMMFH
Q6FQM9_CANGA/941-1050-----FQLF...NEI.........D.FVKDERDSWLE..KKNI---E------YVDIVEE------------FMEQSPRN
J7S621_KAZNA/979-1086-----FQLL...NEI.........N.FVEQERKLWLE..CKNR---E------YVTKLED------------FLAATQNK
A7TMV1_VANPO/947-1055-----FQIL...NEI.........Q.YIEHERESWLL..NKNL---E------YVSIVEE------------FIDNFQT.
A2EA80_TRIVA/110-211-----LSNC.................TVSDVVDWWME..DGNN---D------YFLAFDK------------AVEQSFLK
H2VXG0_CAEJA/87-188-----CV.....ADE.........D.EVRDVVRFWMN..EFNQ---K------YMKIIDE------------DMKEMMF.
C5DE78_LACTC/899-1007-----FKQL...NDI.........G.FVETEREKWIS..HKNK---E------YVSRVEA------------FIQAEASK
E4Y0W8_OIKDI/394-503-----NEFIAQKVEEFGG......ETDLDFMLDSWMT..TGQY---E------FSKEIEG------------RLKVSFST
A3LXW6_PICST/871-982-----FRFL...EDS.........G.FIEEEFDKWSN..MNDL---S------YLNRIEK------------LISASFFP
M7NVD2_PNEMU/825-931-----FNYL...KEF.........D.YIEKEMDNWFH..EQNE---I------YVNYIEN------------YLSLAFSF
Q16UV7_AEDAE/700-806-----...L...NHP.........EAKIKEEIETWVN..GYNN---R------YVLLIEA------------DVHAHLTQ
B3S2G4_TRIAD/728-835-----FTYL...QNM.........G.FLTKAIEEWIQ..HSNL---E------YVKLVER------------SLAEALTT
U9SZG8_RHIID/735-840-----FKYL...SEF.........D.YVEREMDEWFQ..SRNQ---Y------YVTQLEV------------MLSTAL..
E6ZW77_SPORE/1100-1205-----IRYL...WQC.........E.YIDREMDEWFN..ERNQ---R------YVVEVEV------------MLADFFSI
W1QEH2_OGAPD/786-894-----FEYL...QEY.........D.FVDEEMEAWIQ..SKNK---H------YVQHIET------------YLAQKLFN
G7DSK3_MIXOS/1003-1107-----TRYL...FDI.........G.YIERELQDWFH..YRNF---Y------YAVKVEL------------ALASLFGQ
G0SYK2_RHOG2/890-997-----VRYL...HEI.........D.FIERELHDWFQ..ERNL---L------YMVEVEL------------ALATALKT
G4UNU8_NEUT9/912-1019-----YHYL...DGL.........D.YISNEMDDWFL..GRND---S------YVSVIEA------------SLARSFLE
G0QKR2_ICHMG/29-137-----FNYL...SQK.........YDWISQELFRWQE..TEKI---Q------YVTKIEK------------CLLNALNF
Q6CMH7_KLULA/873-982-----FQQL...RGL.........N.YTNKERINWKT..FKNR---E------FVFKVEQ------------FLEQEISK
K5VKD3_PHACS/897-1002-----FRYL...YAA.........D.YIDREMDAWFH..ERNL---H------YVVHIEV------------FLAKAFG.
C9SP12_VERA1/926-1031-----YHYL...DGL.........D.YISNEMDDWFL..GRND---T------YVDLIET------------SLAKAFSD
Q7PSX6_ANOGA/826-936-----...I...FHP.........EAHTVRELEQWVA..VYNE---E------YVLLVEA------------DTHAHLTQ
G0V941_NAUCC/930-1038-----FQLL...SEI.........N.FVTDERNAWLT..QMNR---E------YVSIVEE------------FLSKRQNN
I1CVE6_RHIO9/845-950-----FRYL...NAL.........G.YVQKEMDDWFE..RGNQ---N------YVTQLEL------------SLARALIN
A4VDX0_TETTS/737-848-----FEYLSKMSEQ.........QNWVEEQMQRWKE..QQNL---D------YVNKIET------------CLLKALN.
F1KRH6_ASCSU/839-943-----VG.....SNP.........N.DVQVAFNLWRK..EFNA---R------YVEVIDE------------DLKVAMLN
Q6C3B5_YARLI/788-895-----FQYL...QKM.........D.FVALEMDSWFH..GQNE---A------YVGRIEY------------YLEQCMVP
D3B1Y5_POLPA/11-118-----LNYL...KEI.........N.FVEPEQKLWLG..SENA---N------YVISVEN------------AISEALTP
M3JD48_CANMX/741-852-----FKYL...ESL.........G.YLEMKFTEWNN..LTNF---K------YLEKINS------------IIQYQFFP
PIAA_DICDI/784-892-----LENL...LQN.........NGFVEQEEQLWIT..SENA---T------YVNAIES------------AVSESLSP
H2B1N1_KAZAF/923-1030-----FQLL...NDI.........N.FVEVERQSWLD..HKNI---E------YVSIVEE------------FLSTAQFR
F1QR10_DANRE/602-709-----FSYL...NER.........G.YVSKQLEKWLK..EYNL---K------YVDMIEE------------QLNEALTT
F4PXH0_DICFS/178-285-----LDYL...LGT.........S.FVEQEEKLWLS..GENA---N------YVIQVEG------------AISEALTP
W5JMS9_ANODA/857-967-----...L...NHS.........SAQVLNEIEQWLS..IYNE---R------YVLLIES------------DTHANLTQ
A7SRE9_NEMVE/663-770-----FTYL...QSL.........G.YLHVLLEQWRQ..KFCR---E------YVRWVEE------------LLAESLTT
X6NW59_RETFI/156-269-----LEYL...QQL.........N.WVDRKRFEWLS..VFNQ---R------YTLMLET------------ALMTAVNK
E0VAL0_PEDHC/696-799-----FTFL...SDA.........N.FVQNELENWEK..EYNH---R------YVGLMEA------------DVHDSLTL
G4TRF3_PIRID/978-1085-----FQYL...YET.........G.YIEREMDAWFH..DRNH---Q------YVVLVEV------------YLSQAFSI
K1PHU1_CRAGI/3475-3582-----FKML...SDA.........N.FILNEVQKWEK..TYNV---R------YVHIVED------------LLNEALTT
H3DZM0_PRIPA/58-162-----TR.....KNM.........S.AAREVVDFWMM..KFNA---R------YAATVEE------------EMRMALLG
A8WTI5_CAEBR/102-204-----CA.....NDE.........N.EVRDVTRFWMK..EFNK---T------YLNIIDE------------AMKEMMFH
B7PHW3_IXOSC/733-837-----FKYL...LEA.........N.VLESELSKWDE..VNHL---R------YVKIVED------------VINQAVTW
G1XJT2_ARTOA/962-1069-----YHYL...NEL.........D.YINREMDDWFH..GRND---V------YVDQVEA------------SLARAFSD
E9CA69_CAPO3/787-894-----LKYL...NET.........G.FTAKEMQLWWT..FPAV---D------YVAQVES------------VLASTTSW
Q5K7Q2_CRYNJ/992-1095-----FQYL...NQA.........Q.YIERELESWLA..ERNL---L------YVIEAET------------FISK....
J8LPE6_SACAR/977-1084-----FQLL...NEI.........N.FVKEERDSWLS..KKNI---E------YVHIVEE------------FLKKNQT.
G8JSJ3_ERECY/925-1031-----FNLL...SNI.........L.YVDNERLAWLQ..HKNR---D------YVNKVEE------------FLENEL..
G0QUZ5_ICHMG/441-548-----FNYL...QEK.........YNWIEKMVYKWES..KLNE---E------YAEKLEK------------CLINQLN.
G0W3E1_NAUDC/926-1034-----FQLL...NEI.........N.FVYSERESWLS..QKNK---E------YVSIVEN------------FLAKKQNS
A0EHS6_PARTE/758-868-----FEKI..YKDL.........NEYLLNEIERWKQ..SECE---N------YIEKVEK------------VMCDALE.
G8ZRB4_TORDC/940-1048-----FQLL...NEI.........N.FIEAERKSWLE..SKNK---E------YVLLAED------------FLTANQYT
C3ZJ41_BRAFL/749-856-----FTFL...SEV.........N.YTANVLDKWYK..SFNK---K------YVHLVED------------ELNEALTN
M5E6L0_MALS4/714-818-----FQTM...LRH.........G.LLVSLTELWQR..QEHM---A------YVGRVEQ------------VVAPEQS.
G3AJX3_SPAPN/875-983-----FKYL...EQS.........G.YIDQEFSKWDD..ITDF---Q------YLKKVEL------------LIKY....
T1KEM6_TETUR/667-774-----FKFL...RDT.........N.FLSYEIDRWRK..YFNL---K------YVRIVEN------------SLNEALSY
M5BUI9_THACB/547-654-----FQYL...YNA.........D.YIDREMDGWFH..EQNY---Q------YLVQVEV------------YLARALTP
M2S0T8_COCSN/908-1015-----YHYL...DGL.........D.YITREMDDWFL..GRND---T------YVALIEA------------SMARALAD
K5WVI4_AGABU/760-865-----FRYL...FEA.........G.HIEKEIDNWFH..ERNL---L------YVVDIEI------------FLTKLFNT

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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