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1381  structures 9729  species 75  interactions 75213  sequences 557  architectures

Clan: EFTPs (CL0575)

Summary

Translation proteins of Elongation Factors superfamily Add an annotation

This superfamily is characterised ba a barrel that is formed as a greek-key. It is found as the second domain in many elongation factor proteins, as well as in an elaborated from in two ribosomal proteins and in some other N-terminal domains, eg of AlaX and Gar1 and RimM protein famlies.

This clan contains 7 families and the total number of domains in the clan is 75213. The clan was built by P Coggill.

Members

This clan contains the following 7 member families:

Gar1 GTP_EFTU_D2 NSP2_assoc RIBIOP_C Ribosomal_L3 Ribosomal_L35Ae RimM

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
GTP_EFTU_D2 (PF03144) 50275 (66.8%) View
Ribosomal_L3 (PF00297) 11561 (15.4%) View
RimM (PF01782) 6863 (9.1%) View
RIBIOP_C (PF04950) 2558 (3.4%) View
Gar1 (PF04410) 2437 (3.2%) View
Ribosomal_L35Ae (PF01247) 1517 (2.0%) View
NSP2_assoc (PF14758) 2 (0.0%) View
Total: 7 Total: 75213 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 75 interactions for this clan. More...

Interacting families
A B
eIF2_C GTP_EFTU_D2
eRF1_1 GTP_EFTU_D2
Gar1 Gar1
GTP_EFTU GTP_EFTU_D2
RIBIOP_C
GTP_EFTU_D2 EF1_GNE
EFG_II
EFG_IV
eIF-5_eIF-2B
eIF2_C
EIF_2_alpha
eRF1_1
eRF1_2
GTP_EFTU
GTP_EFTU_D2
GTP_EFTU_D3
IF-2
Ribosom_S12_S23
RNA_replicase_B
GTP_EFTU_D3 GTP_EFTU_D2
PAPS_reduct GTP_EFTU_D2
PRC RimM
Ribosom_S12_S23 GTP_EFTU_D2
Ribosomal_L11_N Ribosomal_L3
Ribosomal_L13 Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L14 Ribosomal_L3
Ribosomal_L15e Ribosomal_L3
Ribosomal_L18p Ribosomal_L3
Ribosomal_L19 Ribosomal_L3
Ribosomal_L23eN Ribosomal_L3
Ribosomal_L24e Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L29 Ribosomal_L3
Ribosomal_L29e Ribosomal_L3
Ribosomal_L3 Ribosomal_L12
Ribosomal_L13
Ribosomal_L14
Ribosomal_L19
Ribosomal_L22
Ribosomal_L24e
Ribosomal_L36e
Ribosomal_L37ae
Ribosomal_L44
Ribosomal_L30_N Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L31e Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L32e Ribosomal_L35Ae
Ribosomal_L34 Ribosomal_L3
Ribosomal_L35Ae Ribosomal_L11
Ribosomal_L11_N
Ribosomal_L19e
Ribosomal_L21e
Ribosomal_L27A
Ribosomal_L3
Ribosomal_L30
Ribosomal_L30_N
Ribosomal_L32e
Ribosomal_L5_C
Ribosomal_L6e
Ribosomal_L37ae Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L37e Ribosomal_L3
Ribosomal_L44 Ribosomal_L3
Ribosomal_L35Ae
Ribosomal_L5 Ribosomal_L35Ae
Ribosomal_L6e Ribosomal_L35Ae
Ribosomal_S19 RimM
Ribosomal_S2 Ribosomal_L3
Ribosomal_S25 GTP_EFTU_D2
RimM PRC
Ribosomal_S19
RimM
TruB_N Gar1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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