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15  structures 703  species 0  interactions 1825  sequences 46  architectures

Clan: Nucleoporin_A (CL0585)

Summary

Nucleoporin superfamily Add an annotation

This is a superfamily of nucleoporins. Nucleoporins are all-beta structures that form part of the nuclear-pore complex.

This clan contains 2 families and the total number of domains in the clan is 1825. The clan was built by P Coggill.

Literature references

  1. Berke IC, Boehmer T, Blobel G, Schwartz TU; , J Cell Biol. 2004;167:591-597.: Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex. PUBMED:15557116 EPMC:15557116

Members

This clan contains the following 2 member families:

Nup188 Nup192

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Nup192 (PF11894) 1040 (57.0%) View
Nup188 (PF10487) 785 (43.0%) View
Total: 2 Total: 1825 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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