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14  structures 343  species 3  interactions 1558  sequences 44  architectures

Clan: DUF1735 (CL0594)


DUF1735-like superfamily Add an annotation

This superfamily includes a number of families that are related to the domain of unknown function DUF1735. These proteins have a beta-sandwich fold.

This clan contains 5 families and the total number of domains in the clan is 1558. The clan was built by A Bateman.


This clan contains the following 5 member families:

DUF1735 DUF4843 DUF4973 DUF4989 DUF4999

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DUF1735 (PF08522) 982 (63.0%) View
DUF4843 (PF16132) 494 (31.7%) View
DUF4973 (PF16343) 65 (4.2%) View
DUF4999 (PF16390) 12 (0.8%) View
DUF4989 (PF16379) 5 (0.3%) View
Total: 5 Total: 1558 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
DUF1735 DUF1735


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...