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449  structures 4644  species 17  interactions 20135  sequences 143  architectures

Clan: Reductase_C (CL0608)

Summary

FAD/NAD-linked reductase C-terminal domain superfamily Add an annotation

This domain is found at the C-terminus of a variety of FAD/NAD-linked reductases.

This clan contains 4 families and the total number of domains in the clan is 20135. The clan was built by A Bateman.

Members

This clan contains the following 4 member families:

AIF_C FCSD-flav_bind Pyr_redox_dim Reductase_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Pyr_redox_dim (PF02852) 16926 (84.1%) View
Reductase_C (PF14759) 2444 (12.1%) View
AIF_C (PF14721) 407 (2.0%) View
FCSD-flav_bind (PF09242) 358 (1.8%) View
Total: 4 Total: 20135 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 17 interactions for this clan. More...

Interacting families
A B
AIF-MLS AIF_C
AIF_C Pyr_redox_2
Cytochrom_C FCSD-flav_bind
Pyr_redox AIF_C
Pyr_redox_dim
Reductase_C
Pyr_redox_2 AIF_C
FCSD-flav_bind
Pyr_redox_dim
Reductase_C
Pyr_redox_dim E3_binding
Pyr_redox
Pyr_redox_2
Pyr_redox_dim
Rhodanese
Reductase_C Fer2
Rieske

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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