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760  structures 8997  species 6  interactions 61775  sequences 387  architectures

Clan: Terp_synthase (CL0613)


Terpenoid synthases superfamily Add an annotation

This superfamily includes a diverse range of terpene synthase enzymes which share an alpha helical core.

This clan contains 6 families and the total number of domains in the clan is 61775. The clan was built by A Bateman.


This clan contains the following 6 member families:

HEPPP_synt_1 polyprenyl_synt SQS_PSY Terpene_synth_C TRI5 UbiA

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
UbiA (PF01040) 24223 (39.2%) View
polyprenyl_synt (PF00348) 22723 (36.8%) View
SQS_PSY (PF00494) 8999 (14.6%) View
Terpene_synth_C (PF03936) 4883 (7.9%) View
TRI5 (PF06330) 560 (0.9%) View
HEPPP_synt_1 (PF07307) 387 (0.6%) View
Total: 6 Total: 61775 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 6 interactions for this clan. More...

Interacting families
polyprenyl_synt polyprenyl_synt
Terpene_synth Terpene_synth_C
Terpene_synth_C Terpene_synth


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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