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946  structures 4352  species 9  interactions 29227  sequences 596  architectures

Clan: Peroxidase (CL0617)


Heme-dependent peroxidases superfamily Add an annotation

This superfamily includes two families of heme-dependent peroxidases that have an all alpha helical fold.

This clan contains 3 families and the total number of domains in the clan is 29227. The clan was built by A Bateman.


This clan contains the following 3 member families:

An_peroxidase peroxidase Peroxidase_ext

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
peroxidase (PF00141) 20709 (70.9%) View
An_peroxidase (PF03098) 8150 (27.9%) View
Peroxidase_ext (PF11895) 368 (1.3%) View
Total: 3 Total: 29227 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 9 interactions for this clan. More...

Interacting families
An_peroxidase An_peroxidase
Cu-oxidase_2 An_peroxidase
Cu-oxidase_3 An_peroxidase
Cytochrom_C peroxidase
peroxidase Cytochrom_C
Peroxidase_ext peroxidase


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...