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98  structures 2339  species 5  interactions 4573  sequences 22  architectures

Clan: CcdB_PemK (CL0624)

Summary

Cell growth inhibitor/plasmid maintenance toxic component superfamily Add an annotation

This superfamily includes cell growth inhibitors and toxin components. These proteins share an SH3-like barrel structure.

This clan contains 3 families and the total number of domains in the clan is 4573. The clan was built by A Bateman.

Members

This clan contains the following 3 member families:

CcdB DUF1918 PemK_toxin

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PemK_toxin (PF02452) 3986 (87.2%) View
DUF1918 (PF08940) 313 (6.8%) View
CcdB (PF01845) 274 (6.0%) View
Total: 3 Total: 4573 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 5 interactions for this clan. More...

Interacting families
A B
CcdB CcdA
CcdB
DNA_topoisoIV CcdB
PemK_toxin MazE_antitoxin
PemK_toxin

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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