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179  structures 294  species 8  interactions 6020  sequences 482  architectures

Clan: PSI (CL0630)

Summary

Plexin fold superfamily Add an annotation

This superfamily includes a disulphide rich domain found in Plexins, semaphorins and some integrin protein. According to SCOP the common core is alpha+beta with two conserved disulfides.

This clan contains 3 families and the total number of domains in the clan is 6020. The clan was built by A Bateman.

Members

This clan contains the following 3 member families:

PSI PSI_integrin Trefoil

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PSI (PF01437) 3708 (61.6%) View
Trefoil (PF00088) 1383 (23.0%) View
PSI_integrin (PF17205) 929 (15.4%) View
Total: 3 Total: 6020 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 8 interactions for this clan. More...

Interacting families
A B
Glyco_hydro_31 Trefoil
LRR_4 PSI
PSI Ig_2
Sema
TIG
Sema PSI
Trefoil Glyco_hydro_31
Trefoil

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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