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31  structures 685  species 0  interactions 7215  sequences 134  architectures

Clan: FG_rpt (CL0647)

Summary

Nucleoporin FG repeat Add an annotation

This clan includes families which contain nucleoporin FG repeats.

This clan contains 2 families and the total number of domains in the clan is 7215. The clan was built by J Mistry.

Literature references

  1. Dolker N, Zachariae U, Grubmuller H;, Biophys J. 2010;98:2653-2661.: Hydrophilic linkers and polar contacts affect aggregation of FG repeat peptides. PUBMED:20513410 EPMC:20513410
  2. Frey S, Richter RP, Gorlich D;, Science. 2006;314:815-817.: FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. PUBMED:17082456 EPMC:17082456

Members

This clan contains the following 2 member families:

Nucleoporin_FG Nucleoporin_FG2

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Nucleoporin_FG (PF13634) 6950 (96.3%) View
Nucleoporin_FG2 (PF15967) 265 (3.7%) View
Total: 2 Total: 7215 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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