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0  structures 247  species 0  interactions 297  sequences 15  architectures

Clan: aG_PT (CL0686)

Summary

Alpha-glutamyl/putrescinyl thymine phosphorylase Add an annotation

This clan includes alpha-glutamyl/putrescinyl thymine phosphorylase related entries. According to sequence analysis several clades have been identified such as Clade-1, a prototypical aG/PT-pyrophoshorylase and Clade-2 pyrophoshorylases which are mainly found mainly in caudoviruses and prophages, where they are usually linked to a P-loop kinase. Several phages possess both a clade-1 aG/PT-pyrophoshorylase domain and a clade-2 protein [1].

This clan contains 3 families and the total number of domains in the clan is 297. The clan was built by S El-Gebali.

Literature references

  1. Iyer LM, Zhang D, Burroughs AM, Aravind L;, Nucleic Acids Res. 2013;41:7635-7655.: Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA. PUBMED:23814188 EPMC:23814188

Members

This clan contains the following 3 member families:

aGPT-Pplase1 aGPT-Pplase2 aGPT-Pplase3

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
aGPT-Pplase1 (PF18723) 237 (79.8%) View
aGPT-Pplase2 (PF18724) 39 (13.1%) View
aGPT-Pplase3 (PF18746) 21 (7.1%) View
Total: 3 Total: 297 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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