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581  structures 748  species 10  interactions 15749  sequences 825  architectures

Clan: C_Lectin (CL0056)


C-type lectin-like superfamily Add an annotation

This clan contains domains that have a C-type lectin fold. Many of these are known or expected to mediate interactions with sugars.

This clan contains 7 families and the total number of domains in the clan is 15749. The clan was built by A Bateman.


This clan contains the following 7 member families:

APT C4 Chordopox_A33R Herpes_UL45 Intimin_C Lectin_C Xlink

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Lectin_C (PF00059) 12227 (77.6%) View
Xlink (PF00193) 1651 (10.5%) View
C4 (PF01413) 1172 (7.4%) View
Intimin_C (PF07979) 389 (2.5%) View
Herpes_UL45 (PF05473) 167 (1.1%) View
APT (PF03440) 77 (0.5%) View
Chordopox_A33R (PF05966) 66 (0.4%) View
Total: 7 Total: 15749 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 10 interactions for this clan. More...

Interacting families
Xlink Xlink
Lectin_C EGF
Intimin_C Big_2
C4 C4


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...