Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
25  structures 902  species 1  interaction 1575  sequences 29  architectures

Clan: Chalcone-like (CL0560)

Summary

Chalcone isomerase-like superfamily Add an annotation

This superfamily is characterised by a fold that is conserved across plants, bacteria and fungi. However, possible key residues necessary for binding naringenin, 4',5,7-trihydroxyflavanone, are not conserved beyond plants.

This clan contains 3 families and the total number of domains in the clan is 1575. The clan was built by P Coggill.

Literature references

  1. Gensheimer M, Mushegian A; , Protein Sci. 2004;13:540-544.: Chalcone isomerase family and fold: no longer unique to plants. PUBMED:14718655 EPMC:14718655

Members

This clan contains the following 3 member families:

Chalcone Chalcone_2 Chalcone_3

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Chalcone_3 (PF16036) 661 (42.0%) View
Chalcone_2 (PF16035) 619 (39.3%) View
Chalcone (PF02431) 295 (18.7%) View
Total: 3 Total: 1575 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There is 1 interaction for this clan. More...

Interacting families
A B
Chalcone Chalcone

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...