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1951  structures 7761  species 45  interactions 62948  sequences 4199  architectures

Clan: Concanavalin (CL0004)


Concanavalin-like lectin/glucanase superfamily Add an annotation

This superfamily includes a diverse range of carbohydrate binding domains and glycosyl hydrolase enzymes that share a common structure.

This clan contains 18 families and the total number of domains in the clan is 62948. The clan was built by A Bateman.


This clan contains the following 18 member families:

Cleaved_Adhesin DUF1080 DUF2401 Gal-bind_lectin Glyco_hydro_11 Glyco_hydro_12 Glyco_hydro_16 Glyco_hydro_7 Laminin_G_1 Laminin_G_2 Laminin_G_3 Lectin_leg-like Lectin_legB MAM Pentaxin Sialidase SKN1 Toxin_R_bind_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Glyco_hydro_16 (PF00722) 10652 (16.9%) View
Laminin_G_2 (PF02210) 10566 (16.8%) View
Laminin_G_3 (PF13385) 10176 (16.2%) View
Glyco_hydro_7 (PF00840) 5602 (8.9%) View
MAM (PF00629) 4994 (7.9%) View
Lectin_legB (PF00139) 3428 (5.4%) View
Gal-bind_lectin (PF00337) 3115 (4.9%) View
DUF1080 (PF06439) 2555 (4.1%) View
Glyco_hydro_12 (PF01670) 2547 (4.0%) View
Laminin_G_1 (PF00054) 2106 (3.3%) View
Pentaxin (PF00354) 1444 (2.3%) View
Lectin_leg-like (PF03388) 1386 (2.2%) View
Glyco_hydro_11 (PF00457) 1334 (2.1%) View
SKN1 (PF03935) 1297 (2.1%) View
Sialidase (PF02973) 807 (1.3%) View
Cleaved_Adhesin (PF07675) 353 (0.6%) View
DUF2401 (PF10287) 342 (0.5%) View
Toxin_R_bind_N (PF07953) 244 (0.4%) View
Total: 18 Total: 62948 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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