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35  structures 28  species 4  interactions 4986  sequences 234  architectures

Clan: DBL (CL0195)


Duff-binding like superfamily Add an annotation

This clan includes DBL (Duffy-binding like) domains from a variety of plasmodium surface proteins.

This clan contains 2 families and the total number of domains in the clan is 4986. The clan was built by A Bateman.

Literature references

  1. Tolia NH, Enemark EJ, Sim BK, Joshua-Tor L; , Cell 2005;122:183-193.: Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. PUBMED:16051144 EPMC:16051144


This clan contains the following 2 member families:

Duffy_binding PFEMP

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Duffy_binding (PF05424) 3284 (65.9%) View
PFEMP (PF03011) 1702 (34.1%) View
Total: 2 Total: 4986 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 4 interactions for this clan. More...

Interacting families
Duffy_binding Duffy_binding
NTS Duffy_binding


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...