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4564  structures 9975  species 336  interactions 697448  sequences 32127  architectures

Clan: E-set (CL0159)

Summary

Ig-like fold superfamily (E-set) Add an annotation

This clan includes a diverse range of domains that have an Ig-like fold and appear to be distantly related to each other. The clan includes: PKD domains, cadherins and several families of bacterial Ig-like domains as well as viral tail fibre proteins. it also includes several Fibronectin type III domain-containing families.

This clan contains 218 families and the total number of domains in the clan is 697448. The clan was built by RD Finn and A Bateman.

Members

This clan contains the following 218 member families:

A2M A2M_BRD A2M_recep Adeno_GP19K AlcCBM31 Alpha-amylase_N Alpha_adaptinC2 Alpha_E2_glycop Arch_flagellin Arylsulfotran_N ASF1_hist_chap ATG19_autophagy BACON Big_1 Big_10 Big_11 Big_2 Big_3 Big_3_2 Big_3_3 Big_3_5 Big_4 Big_5 Big_6 Big_7 Big_8 Big_9 Bile_Hydr_Trans BiPBP_C bMG1 bMG10 bMG3 bMG5 bMG6 BslA BsuPI Cadherin Cadherin-like Cadherin_2 Cadherin_3 Cadherin_4 Cadherin_5 Cadherin_pro CagX Calx-beta Candida_ALS_N CARDB CBM39 CBM_X2 CD45 CelD_N Ceramidse_alk_C CHB_HEX_C CHB_HEX_C_1 ChitinaseA_N ChiW_Ig_like CHU_C Coatamer_beta_C COP-gamma_platf CopC Cyc-maltodext_N Cytomega_US3 DsbC DUF11 DUF1410 DUF1425 DUF1929 DUF2271 DUF3244 DUF3327 DUF3416 DUF3458 DUF3501 DUF3823_C DUF3859 DUF3872 DUF4165 DUF4179 DUF4426 DUF4448 DUF4469 DUF4625 DUF4879 DUF4981 DUF4982 DUF5001 DUF5008 DUF5011 DUF5065 DUF5115 DUF525 DUF5643 DUF916 EB_dh ECD EpoR_lig-bind ERAP1_C EstA_Ig_like Filamin FixG_C Flavi_glycop_C FlgD_ig fn3 Fn3-like fn3_2 fn3_4 fn3_5 fn3_6 FN3_7 Fn3_assoc fn3_PAP GBS_Bsp-like Glucodextran_B Glyco_hydro2_C5 Glyco_hydro_2 Glyco_hydro_61 Gmad2 GMP_PDE_delta GPI-anchored Hanta_G1 He_PIG He_PIG_assoc HECW_N HemeBinding_Shp Hemocyanin_C Herpes_BLLF1 HYR IFNGR1 Ig_GlcNase Ig_mannosidase IL12p40_C Il13Ra_Ig IL17R_fnIII_D1 IL17R_fnIII_D2 IL2RB_N1 IL3Ra_N IL4Ra_N IL6Ra-bind Inhibitor_I42 Inhibitor_I71 Integrin_alpha2 Interfer-bind Invasin_D3 IRK_C IrmA Iron_transport LEA_2 Lep_receptor_Ig LIFR_N Lipase_bact_N LPMO_10 LRR_adjacent LTD Mannosidase_ig MG1 MG2 MG3 MG4 Mo-co_dimer N_BRCA1_IG Na_K-ATPase NEAT Neocarzinostat Neurexophilin NPCBM_assoc PapD_C PBP-Tp47_c Peptidase_C25_C Phlebovirus_G2 PhoD_N PKD PKD_2 PKD_3 Pollen_allerg_1 Pox_vIL-18BP Pur_ac_phosph_N Qn_am_d_aII Qn_am_d_aIII RabGGT_insert Reeler REJ RET_CLD1 RET_CLD3 RET_CLD4 RGI_lyase RHD_dimer Rho_GDI Rib SCAB-Ig SKICH SLAM SoxZ SprB SusE SVA SWM_repeat T2SS-T3SS_pil_N Tafi-CsgC TarS_C1 TcA_RBD TcfC TIG TIG_2 TIG_plexin Tissue_fac Top6b_C Transglut_C Transglut_N TRAP_beta Tuberculin UL16 Velvet WIF Wzt_C Y_Y_Y YBD ZirS_C Zona_pellucida

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
fn3 (PF00041) 138558 (19.9%) View
Cadherin (PF00028) 100996 (14.5%) View
Filamin (PF00630) 21821 (3.1%) View
TIG (PF01833) 19496 (2.8%) View
Big_9 (PF17963) 17373 (2.5%) View
PKD (PF00801) 15672 (2.2%) View
Calx-beta (PF03160) 15066 (2.2%) View
Fn3-like (PF14310) 14887 (2.1%) View
Glyco_hydro_2 (PF00703) 13523 (1.9%) View
DUF11 (PF01345) 10804 (1.5%) View
Cadherin_3 (PF16184) 10023 (1.4%) View
Big_2 (PF02368) 9457 (1.4%) View
SprB (PF13573) 8556 (1.2%) View
ERAP1_C (PF11838) 8355 (1.2%) View
CHU_C (PF13585) 7209 (1.0%) View
Big_6 (PF17936) 7158 (1.0%) View
LTD (PF00932) 6971 (1.0%) View
Y_Y_Y (PF07495) 6407 (0.9%) View
Big_5 (PF13205) 5947 (0.9%) View
fn3_6 (PF17766) 5862 (0.8%) View
Pur_ac_phosph_N (PF16656) 5697 (0.8%) View
LEA_2 (PF03168) 5684 (0.8%) View
A2M (PF00207) 5499 (0.8%) View
Zona_pellucida (PF00100) 5482 (0.8%) View
He_PIG (PF05345) 5444 (0.8%) View
MG2 (PF01835) 4950 (0.7%) View
HYR (PF02494) 4875 (0.7%) View
A2M_BRD (PF07703) 4765 (0.7%) View
DsbC (PF11412) 4758 (0.7%) View
Cadherin_2 (PF08266) 4683 (0.7%) View
Big_7 (PF17957) 4627 (0.7%) View
Glyco_hydro_61 (PF03443) 4374 (0.6%) View
Alpha_adaptinC2 (PF02883) 4235 (0.6%) View
Pollen_allerg_1 (PF01357) 4179 (0.6%) View
Mo-co_dimer (PF03404) 4097 (0.6%) View
CARDB (PF07705) 4033 (0.6%) View
FlgD_ig (PF13860) 3732 (0.5%) View
Cadherin_4 (PF17803) 3601 (0.5%) View
LPMO_10 (PF03067) 3526 (0.5%) View
Big_3_5 (PF16640) 3496 (0.5%) View
PhoD_N (PF16655) 3463 (0.5%) View
IRK_C (PF17655) 3460 (0.5%) View
CopC (PF04234) 3415 (0.5%) View
DUF525 (PF04379) 3351 (0.5%) View
Velvet (PF11754) 3296 (0.5%) View
CHB_HEX_C_1 (PF13290) 3160 (0.5%) View
DUF4981 (PF16353) 3140 (0.5%) View
Big_10 (PF17964) 3066 (0.4%) View
Integrin_alpha2 (PF08441) 3001 (0.4%) View
bMG10 (PF17973) 2864 (0.4%) View
DUF4982 (PF16355) 2731 (0.4%) View
GPI-anchored (PF10342) 2709 (0.4%) View
DUF1929 (PF09118) 2698 (0.4%) View
FixG_C (PF11614) 2687 (0.4%) View
DUF3458 (PF11940) 2665 (0.4%) View
Glyco_hydro2_C5 (PF18565) 2556 (0.4%) View
DUF5011 (PF16403) 2494 (0.4%) View
T2SS-T3SS_pil_N (PF13629) 2430 (0.3%) View
A2M_recep (PF07677) 2376 (0.3%) View
Cadherin-like (PF12733) 2312 (0.3%) View
Transglut_C (PF00927) 2218 (0.3%) View
MG3 (PF17791) 2216 (0.3%) View
CagX (PF03524) 2144 (0.3%) View
Mannosidase_ig (PF17786) 1881 (0.3%) View
BiPBP_C (PF06832) 1840 (0.3%) View
BACON (PF13004) 1838 (0.3%) View
RHD_dimer (PF16179) 1834 (0.3%) View
Wzt_C (PF14524) 1822 (0.3%) View
bMG3 (PF11974) 1822 (0.3%) View
DUF3416 (PF11896) 1773 (0.3%) View
NPCBM_assoc (PF10633) 1763 (0.3%) View
Cadherin_5 (PF17892) 1757 (0.3%) View
N_BRCA1_IG (PF16158) 1709 (0.2%) View
Rho_GDI (PF02115) 1691 (0.2%) View
Ig_mannosidase (PF17753) 1587 (0.2%) View
Reeler (PF02014) 1572 (0.2%) View
PapD_C (PF02753) 1566 (0.2%) View
Fn3_assoc (PF13287) 1548 (0.2%) View
Big_4 (PF07532) 1535 (0.2%) View
CelD_N (PF02927) 1520 (0.2%) View
Na_K-ATPase (PF00287) 1518 (0.2%) View
fn3_5 (PF06280) 1515 (0.2%) View
bMG5 (PF17972) 1510 (0.2%) View
MG4 (PF17789) 1478 (0.2%) View
COP-gamma_platf (PF08752) 1436 (0.2%) View
Tissue_fac (PF01108) 1434 (0.2%) View
SoxZ (PF08770) 1431 (0.2%) View
bMG6 (PF17962) 1409 (0.2%) View
Ceramidse_alk_C (PF17048) 1407 (0.2%) View
Big_1 (PF02369) 1384 (0.2%) View
ASF1_hist_chap (PF04729) 1378 (0.2%) View
Interfer-bind (PF09294) 1363 (0.2%) View
REJ (PF02010) 1337 (0.2%) View
Transglut_N (PF00868) 1294 (0.2%) View
TIG_plexin (PF17960) 1283 (0.2%) View
Coatamer_beta_C (PF07718) 1265 (0.2%) View
DUF4179 (PF13786) 1221 (0.2%) View
Rib (PF08428) 1155 (0.2%) View
Alpha-amylase_N (PF02903) 1124 (0.2%) View
TIG_2 (PF18020) 1099 (0.2%) View
Big_3 (PF07523) 1091 (0.2%) View
Neurexophilin (PF06312) 1076 (0.2%) View
DUF916 (PF06030) 1065 (0.2%) View
SKICH (PF17751) 1034 (0.1%) View
YBD (PF17725) 1016 (0.1%) View
DUF2271 (PF10029) 990 (0.1%) View
RGI_lyase (PF18370) 977 (0.1%) View
IL6Ra-bind (PF09240) 970 (0.1%) View
GMP_PDE_delta (PF05351) 958 (0.1%) View
SusE (PF14292) 945 (0.1%) View
continued
Pfam family Num. domains Alignment
Bile_Hydr_Trans (PF04775) 924 (0.1%) View
Hemocyanin_C (PF03723) 915 (0.1%) View
Ig_GlcNase (PF18368) 900 (0.1%) View
Arch_flagellin (PF01917) 867 (0.1%) View
Big_3_2 (PF12245) 848 (0.1%) View
Inhibitor_I42 (PF09394) 843 (0.1%) View
Cadherin_pro (PF08758) 833 (0.1%) View
Gmad2 (PF10648) 806 (0.1%) View
CBM_X2 (PF03442) 788 (0.1%) View
Big_8 (PF17961) 773 (0.1%) View
NEAT (PF05031) 769 (0.1%) View
EpoR_lig-bind (PF09067) 723 (0.1%) View
Invasin_D3 (PF09134) 713 (0.1%) View
Cyc-maltodext_N (PF09087) 704 (0.1%) View
TRAP_beta (PF05753) 700 (0.1%) View
fn3_PAP (PF17808) 676 (0.1%) View
WIF (PF02019) 652 (0.1%) View
GBS_Bsp-like (PF08481) 649 (0.1%) View
EB_dh (PF09459) 625 (0.1%) View
Iron_transport (PF10634) 587 (0.1%) View
DUF5643 (PF18705) 556 (0.1%) View
SWM_repeat (PF13753) 556 (0.1%) View
Lep_receptor_Ig (PF06328) 541 (0.1%) View
fn3_2 (PF16893) 529 (0.1%) View
DUF4426 (PF14467) 510 (0.1%) View
CHB_HEX_C (PF03174) 497 (0.1%) View
MG1 (PF17790) 448 (0.1%) View
DUF1425 (PF07233) 413 (0.1%) View
PKD_2 (PF16407) 405 (0.1%) View
Arylsulfotran_N (PF17425) 397 (0.1%) View
DUF3327 (PF11806) 395 (0.1%) View
SCAB-Ig (PF16709) 381 (0.1%) View
CBM39 (PF15886) 373 (0.1%) View
BsuPI (PF12690) 373 (0.1%) View
Phlebovirus_G2 (PF07245) 372 (0.1%) View
DUF4448 (PF14610) 364 (0.1%) View
fn3_4 (PF16794) 360 (0.1%) View
DUF3501 (PF12007) 340 (0.0%) View
DUF4625 (PF15418) 334 (0.0%) View
HECW_N (PF16562) 330 (0.0%) View
DUF3872 (PF12988) 321 (0.0%) View
Big_3_3 (PF13750) 305 (0.0%) View
EstA_Ig_like (PF18435) 287 (0.0%) View
DUF3823_C (PF18003) 280 (0.0%) View
ECD (PF18432) 275 (0.0%) View
ChitinaseA_N (PF08329) 275 (0.0%) View
DUF3859 (PF12975) 268 (0.0%) View
DUF4469 (PF14734) 253 (0.0%) View
bMG1 (PF17970) 246 (0.0%) View
Lipase_bact_N (PF12262) 228 (0.0%) View
IL17R_fnIII_D1 (PF16556) 217 (0.0%) View
TcfC (PF16967) 195 (0.0%) View
IL17R_fnIII_D2 (PF16578) 191 (0.0%) View
PKD_3 (PF16820) 178 (0.0%) View
IL12p40_C (PF10420) 166 (0.0%) View
DUF3244 (PF11589) 163 (0.0%) View
Candida_ALS_N (PF11766) 159 (0.0%) View
Top6b_C (PF18000) 150 (0.0%) View
He_PIG_assoc (PF10632) 145 (0.0%) View
IL4Ra_N (PF09238) 137 (0.0%) View
RET_CLD1 (PF17756) 136 (0.0%) View
RET_CLD4 (PF17813) 133 (0.0%) View
RET_CLD3 (PF17812) 133 (0.0%) View
LRR_adjacent (PF08191) 129 (0.0%) View
Qn_am_d_aIII (PF09099) 126 (0.0%) View
Qn_am_d_aII (PF14930) 115 (0.0%) View
IL3Ra_N (PF18611) 109 (0.0%) View
FN3_7 (PF18447) 109 (0.0%) View
Neocarzinostat (PF00960) 106 (0.0%) View
DUF4879 (PF16219) 95 (0.0%) View
IL2RB_N1 (PF18707) 94 (0.0%) View
RabGGT_insert (PF07711) 94 (0.0%) View
DUF5001 (PF16392) 84 (0.0%) View
DUF5008 (PF16400) 74 (0.0%) View
CD45 (PF12567) 74 (0.0%) View
DUF1410 (PF07198) 72 (0.0%) View
DUF5115 (PF17142) 70 (0.0%) View
Peptidase_C25_C (PF03785) 68 (0.0%) View
IFNGR1 (PF07140) 67 (0.0%) View
SVA (PF05326) 66 (0.0%) View
LIFR_N (PF18207) 64 (0.0%) View
Il13Ra_Ig (PF18001) 63 (0.0%) View
HemeBinding_Shp (PF11545) 63 (0.0%) View
TarS_C1 (PF18674) 60 (0.0%) View
SLAM (PF06214) 59 (0.0%) View
Tafi-CsgC (PF10610) 48 (0.0%) View
ATG19_autophagy (PF12744) 40 (0.0%) View
Herpes_BLLF1 (PF05109) 34 (0.0%) View
BslA (PF17735) 31 (0.0%) View
PBP-Tp47_c (PF14888) 31 (0.0%) View
Inhibitor_I71 (PF12628) 29 (0.0%) View
DUF4165 (PF13752) 29 (0.0%) View
IrmA (PF18673) 27 (0.0%) View
TcA_RBD (PF18518) 25 (0.0%) View
ChiW_Ig_like (PF18683) 22 (0.0%) View
Adeno_GP19K (PF04881) 22 (0.0%) View
AlcCBM31 (PF11606) 14 (0.0%) View
Big_11 (PF18200) 13 (0.0%) View
Cytomega_US3 (PF05963) 13 (0.0%) View
DUF5065 (PF16723) 9 (0.0%) View
Pox_vIL-18BP (PF05566) 9 (0.0%) View
Hanta_G1 (PF01567) 7 (0.0%) View
Glucodextran_B (PF09136) 6 (0.0%) View
Alpha_E2_glycop (PF00943) 5 (0.0%) View
Tuberculin (PF12198) 4 (0.0%) View
UL16 (PF17622) 3 (0.0%) View
Flavi_glycop_C (PF02832) 3 (0.0%) View
ZirS_C (PF16583) 2 (0.0%) View
Total: 218 Total: 697448
No alignment ℹ
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 336 interactions for this clan. More...

Interacting families
A B
A2M A2M
A2M_BRD
A2M_recep
CompInhib_SCIN
MG2
NTR
SSL_OB
Stap_Strp_tox_C
Sushi
Trypsin
V-set
A2M_BRD A2M
A2M_BRD
CompInhib_SCIN
Stap_Strp_tox_C
Sushi
V-set
A2M_recep A2M
A2M_recep
CompInhib_SCIN
NTR
TED_complement
Trypsin
AlcCBM31 AlcCBM31
Alpha-amylase Alpha-amylase_N
Cyc-maltodext_N
DUF3416
TIG
Alpha-amylase_C TIG
Alpha-amylase_N Alpha-amylase
Alpha-amylase_N
Alpha_adaptinC2 Alpha_adaptin_C
Alpha_adaptinC2
B2-adapt-app_C
Alpha_E1_glycop Alpha_E2_glycop
Alpha_E2_glycop Alpha_E1_glycop
Alpha_E2_glycop
Peptidase_S3
Alpha_E3_glycop Alpha_E2_glycop
ANATO A2M_recep
Ank_2 TIG
Ank_4 TIG
Antig_Caf1 PapD_C
Arf GMP_PDE_delta
ASF1_hist_chap ASF1_hist_chap
HIRA_B
Histone
Atg8 ATG19_autophagy
BAAT_C Bile_Hydr_Trans
Bgal_small_N Glyco_hydro_2
Big_1 Big_1
Big_2
Invasin_D3
Big_2 Big_2
Intimin_C
Big_3 LRR_5
Bile_Hydr_Trans BAAT_C
Bromodomain ASF1_hist_chap
C1-set Adeno_GP19K
Cytomega_US3
SVA
Cadherin Cadherin
Lectin_C
CagX CagX
TrbI
Calx-beta Calx-beta
CARDB CARDB
Cation_ATPase_C Na_K-ATPase
CBM_4_9 CelD_N
CelD_N Glyco_hydro_9
CH fn3
CHB_HEX CHB_HEX_C
ChitinaseA_N ChitinaseA_N
Glyco_hydro_18
CompInhib_SCIN A2M
A2M_BRD
A2M_recep
CopC CopC
Cyc-maltodext_N Alpha-amylase
Cyc-maltodext_N
Cytomega_US3 C1-set
MHC_I
Dehyd-heme_bind Qn_am_d_aII
DPBB_1 Pollen_allerg_1
DsbC DsbC
Redoxin
Thioredoxin_7
DUF1425 DUF1425
DUF3244 DUF3244
DUF3327 DUF3327
Esterase
DUF3416 Alpha-amylase
DUF3416
DUF3501 DUF3501
DUF3859 DUF3859
DUF4426 DUF4426
DUF525 DUF525
EGF Interfer-bind
Tissue_fac
EPO_TPO EpoR_lig-bind
fn3
EpoR_lig-bind EPO_TPO
EpoR_lig-bind
fn3
ERAP1_C Corona_S1
ERAP1_C
Peptidase_M1
Tachykinin
Esterase DUF3327
FG-GAP Integrin_alpha2
Filamin Filamin
Integrin_b_cyt
Fimbrial PapD_C
FimH_man-bind PapD_C
Flavi_glycop_C Flavi_glycop_C
Flavi_glycoprot
V-set
Flavi_glycoprot Flavi_glycop_C
FlgD_ig FlgD_ig
FLgD_tudor
FLgD_tudor FlgD_ig
fn3 EPO_TPO
EpoR_lig-bind
fn3
Glyco_hydro_28
HH_signal
Hormone_1
I-set
IL2
IL6
Lectin_C
LIF_OSM
Pectate_lyase_3
Pkinase
RGM_C
RGM_N
V-set
Fn3-like Glyco_hydro_3
Glyco_hydro_3_C
Forkhead TIG
Gla Interfer-bind
Globin NEAT
Glucodextran_B Glucodextran_C
Glyco_hydro_15 Glucodextran_B
Glyco_hydro_2 Bgal_small_N
Glyco_hydro_2
Glyco_hydro_2_C
Glyco_hydro_2_N
Glyco_hydro_20 CHB_HEX_C
Glyco_hydro_28 fn3
Glyco_hydro_2_C Glyco_hydro_2
Glyco_hydro_2_N Glyco_hydro_2
Glyco_hydro_3 Fn3-like
Glyco_hydro_3_C Fn3-like
Glyco_hydro_61 Glyco_hydro_61
Glyco_hydro_9 CelD_N
GMP_PDE_delta G-alpha
GMP_PDE_delta
HemeBinding_Shp HemeBinding_Shp
Hemocyanin_C Hemocyanin_C
Hemocyanin_M
Hemocyanin_N
Hemocyanin_M Hemocyanin_C
Hemocyanin_N Hemocyanin_C
HH_signal fn3
HN SLAM
Hormone_1 EpoR_lig-bind
fn3
Hormone_recep fn3
I-set fn3
IFN-gamma IFNGR1
Tissue_fac
IFNGR1 IFN-gamma
IFNGR1
ig fn3
Ig_2 fn3
IL10 Interfer-bind
Tissue_fac
IL12p40_C IL12
IL6
IL13 IL4Ra_N
IL15 fn3
IL6Ra-bind
IL2 fn3
IL6Ra-bind
IL22 Tissue_fac
IL28A Tissue_fac
IL4 fn3
IL4Ra_N
IL6Ra-bind
IL5 IL6Ra-bind
IL6 IL12p40_C
IL6Ra-bind
IL6Ra-bind fn3
IL2
IL5
IL6
IL6Ra-bind
LIF_OSM
IL7 fn3
Inhibitor_I42 Inhibitor_I42
Peptidase_C1
Integrin_alpha2 Integrin_alpha2
Integrin_B_tail
Integrin_beta
Interfer-bind EGF
IL22
Interfer-bind
Interferon
Tissue_fac
Interferon Interfer-bind
Tissue_fac
Intimin_C Big_2
Iron_transport Iron_transport
Kelch_1 DUF1929
Lactonase PKD
LAG1-DNAbind TIG
Lep_receptor_Ig IL6Ra-bind
Lipocalin fn3
LPMO_10 LPMO_10
LRR_4 Cadherin
LRR_adjacent
TIG
LRR_6 LRR_adjacent
LRR_adjacent LRR_4
LRR_adjacent
Sema
LTD LTD
MatE fn3
MG2 A2M
A2M_BRD
A2M_recep
MG2
Stap_Strp_tox_C
Sushi
TED_complement
Trypsin
MHC_I Adeno_GP19K
Cytomega_US3
SVA
Mo-co_dimer Cytochrome_CBB3
Mo-co_dimer
Oxidored_molyb
Na_K-ATPase ATP1G1_PLM_MAT8
Cation_ATPase_C
NEAT Globin
NEAT
Neocarzinostat Neocarzinostat
NPCBM_assoc F5_F8_type_C
NPCBM_assoc
Oxidored_molyb Mo-co_dimer
PapD_C Antig_Caf1
Fimbrial
Fimbrial_K88
FimH_man-bind
PapC_C
PapD_C
PapD_N
PapG_C
PapG_N
Usher
PapD_N PapD_C
PBP-Tp47_a PBP-Tp47_c
PBP-Tp47_c PBP-Tp47_a
PBP-Tp47_c
Peptidase_C1 Inhibitor_I42
Inhibitor_I71
Peptidase_C25 Peptidase_C25_C
Peptidase_M1 DUF3458
ERAP1_C
Peptidase_S3 Alpha_E2_glycop
Peptidase_S8 CHU_C
fn3_5
PKD Lactonase
PKD
Pollen_allerg_1 Pollen_allerg_1
Pox_vIL-18BP IL1
PPTA RabGGT_insert
PSI TIG
Qn_am_d_aII QH-AmDH_gamma
Qn_am_d_aIII
Qn_am_d_aIV
Qn_am_d_aIII Qn_am_d_aIV
RabGGT_insert LRR_1
SQHop_cyclase_N
Ras GMP_PDE_delta
Rho_GDI
TIG
Redoxin DsbC
Reeler Reeler
Reg_prop Y_Y_Y
RHD_DNA_bind TIG
Rho_GDI Rho_GDI
Saf-Nte_pilin PapD_C
Sema TIG
SLAM HN
SoxY SoxZ
SoxZ SoxY
SoxZ
Sushi A2M
TED_complement A2M_recep
MG2
Thioredoxin_2 DsbC
Thioredoxin_7 DsbC
TIG Ank_2
Ank_4
bZIP_1
CBM_20
Forkhead
MamL-1
RHD_DNA_bind
Sema
TIG
Tissue_fac EGF
IFNGR1
IL10
IL22
Interfer-bind
Interferon
Trypsin
Transglut_C Transglut_C
Transglut_core
Transglut_N
Transglut_core Transglut_C
Transglut_N
Transglut_N Transglut_C
Transglut_core
TrbI CagX
Trypsin A2M_recep
Tissue_fac
Usher PapD_C
WIF hEGF
Wzt_C Wzt_C
Y_Y_Y Reg_prop
Y_Y_Y
Zona_pellucida Zona_pellucida

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...