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19  structures 1032  species 1  interaction 9402  sequences 106  architectures

Clan: FF (CL0584)


FF domain Add an annotation

This superfamily contains FF domains.

This clan contains 2 families and the total number of domains in the clan is 9402. The clan was built by R Eberhardt.

Literature references

  1. Bedford MT, Leder P; , Trends Biochem Sci 1999;24:264-265.: The FF domain: a novel motif that often accompanies WW domains. PUBMED:10390614 EPMC:10390614


This clan contains the following 2 member families:


External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
FF (PF01846) 8950 (95.2%) View
RhoGAP-FF1 (PF16512) 452 (4.8%) View
Total: 2 Total: 9402 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There is 1 interaction for this clan. More...

Interacting families


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...