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77  structures 1831  species 8  interactions 3860  sequences 75  architectures

Clan: GH57_38_middle (CL0599)


Families 57/38 glycoside transferase middle domain superfamily Add an annotation

This clan contains 3 families and the total number of domains in the clan is 3860. The clan was built by A Bateman.


This clan contains the following 3 member families:

Alpha-mann_mid DUF1925 DUF1957

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Alpha-mann_mid (PF09261) 3259 (84.4%) View
DUF1957 (PF09210) 484 (12.5%) View
DUF1925 (PF09094) 117 (3.0%) View
Total: 3 Total: 3860 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 8 interactions for this clan. More...

Interacting families
Alpha-mann_mid Alpha-mann_mid
DUF1925 DUF1926
Glyco_hydro_38 Alpha-mann_mid
Glyco_hydro_57 DUF1925


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...