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125  structures 4786  species 7  interactions 20178  sequences 249  architectures

Clan: GH_CE (CL0158)


Glycoside hydrolase/deacetylase superfamily Add an annotation

This superfamily contains diverse enzymes that act on carbohydrates including both hydrolases and deacetylases.

This clan contains 6 families and the total number of domains in the clan is 20178. The clan was built by A Bateman.


This clan contains the following 6 member families:

DUF2334 Glyco_hydro_38 Glyco_hydro_57 LamB_YcsF Polysacc_deac_1 Polysacc_deac_3

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Polysacc_deac_1 (PF01522) 13288 (65.9%) View
Glyco_hydro_38 (PF01074) 2799 (13.9%) View
LamB_YcsF (PF03746) 2484 (12.3%) View
Glyco_hydro_57 (PF03065) 1145 (5.7%) View
DUF2334 (PF10096) 444 (2.2%) View
Polysacc_deac_3 (PF15421) 18 (0.1%) View
Total: 6 Total: 20178 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 7 interactions for this clan. More...

Interacting families
LamB_YcsF LamB_YcsF
Glyco_hydro_57 Glyco_hydro_57
Glyco_hydro_38 Glyco_hydro_38C
Polysacc_deac_1 Polysacc_deac_1


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...