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4640  structures 1944  species 0  interactions 70735  sequences 963  architectures

Clan: Histone (CL0012)

Summary

Histone superfamily Add an annotation

Members of this clan all possess a histone fold. Generally proteins in this clan are DNA binding.

This clan contains 17 families and the total number of domains in the clan is 70735. The clan was built by A Bateman.

Members

This clan contains the following 17 member families:

Bromo_TP Bromo_TP_like CBFD_NFYB_HMF CENP-S CENP-T_C CENP-W CENP-X DUF1931 Histone PAF TAF TAF4 TAFII28 TFIID-18kDa TFIID-31kDa TFIID_20kDa TFIID_30kDa

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Histone (PF00125) 30205 (42.7%) View
CBFD_NFYB_HMF (PF00808) 13408 (19.0%) View
CENP-T_C (PF15511) 4215 (6.0%) View
Bromo_TP (PF07524) 3960 (5.6%) View
TFIID-18kDa (PF02269) 3054 (4.3%) View
TAF4 (PF05236) 2779 (3.9%) View
TAF (PF02969) 2444 (3.5%) View
TFIID_20kDa (PF03847) 2120 (3.0%) View
TFIID-31kDa (PF02291) 1921 (2.7%) View
TAFII28 (PF04719) 1750 (2.5%) View
TFIID_30kDa (PF03540) 1656 (2.3%) View
CENP-S (PF15630) 1168 (1.7%) View
CENP-X (PF09415) 1081 (1.5%) View
PAF (PF15715) 381 (0.5%) View
CENP-W (PF15510) 352 (0.5%) View
DUF1931 (PF09123) 203 (0.3%) View
Bromo_TP_like (PF17027) 38 (0.1%) View
Total: 17 Total: 70735 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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