Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 350  species 0  interactions 425  sequences 4  architectures

Clan: Holin-II (CL0563)


Bacteriophage holin superfamily II Add an annotation

This superfamily is characterised by phage holins of one or two transmembrane domains. It includes the P21 Holin S, the T7 Holin, the HP1 Holin and the Pseudomonas phage F116 Holin families.

This clan contains 4 families and the total number of domains in the clan is 425. The clan was built by P Coggill.


This clan contains the following 4 member families:

Phage_holin_2_1 Phage_holin_2_2 Phage_holin_2_3 Phage_holin_2_4

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Phage_holin_2_3 (PF16080) 155 (36.5%) View
Phage_holin_2_2 (PF10746) 112 (26.4%) View
Phage_holin_2_1 (PF04971) 110 (25.9%) View
Phage_holin_2_4 (PF16082) 48 (11.3%) View
Total: 4 Total: 425 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...