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93  structures 1708  species 3  interactions 3529  sequences 44  architectures

Clan: IDO-like (CL0380)


Indolic compounds 2,3-dioxygenase-like superfamily Add an annotation

Superfamily contains bacterial tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase-like families.

This clan contains 4 families and the total number of domains in the clan is 3529. The clan was built by A Bateman.


This clan contains the following 4 member families:

DUF1864 Hs1pro-1_C IDO Trp_dioxygenase

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Trp_dioxygenase (PF03301) 1874 (53.1%) View
IDO (PF01231) 1502 (42.6%) View
Hs1pro-1_C (PF07014) 100 (2.8%) View
DUF1864 (PF08933) 53 (1.5%) View
Total: 4 Total: 3529 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
DUF1864 DUF1864
Trp_dioxygenase Trp_dioxygenase


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...