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116  structures 8017  species 2  interactions 22249  sequences 85  architectures

Clan: IHF-likeDNA-bdg (CL0548)


IHF-like DNA-binding protein superfamily Add an annotation

This superfamily is characterised by being a dimer of identical subunits of a core of four helices in a bundle, partly opened, capped with a beta-sheet. All members appear to be prokaryotic DNA-binding domains.

This clan contains 8 families and the total number of domains in the clan is 22249. The clan was built by P Coggill.


This clan contains the following 8 member families:

Bac_DNA_binding HU-CCDC81_bac_1 HU-CCDC81_bac_2 HU-CCDC81_euk_1 HU-CCDC81_euk_2 HU-DNA_bdg HU-HIG Tra_M

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Bac_DNA_binding (PF00216) 18677 (83.9%) View
HU-HIG (PF18291) 1501 (6.7%) View
HU-CCDC81_bac_1 (PF18174) 649 (2.9%) View
HU-CCDC81_bac_2 (PF18175) 554 (2.5%) View
HU-CCDC81_euk_2 (PF18289) 388 (1.7%) View
HU-CCDC81_euk_1 (PF14908) 254 (1.1%) View
HU-DNA_bdg (PF14848) 197 (0.9%) View
Tra_M (PF05261) 29 (0.1%) View
Total: 8 Total: 22249 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 2 interactions for this clan. More...

Interacting families
Bac_DNA_binding Bac_DNA_binding
Tra_M Tra_M


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...