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11  structures 455  species 3  interactions 1103  sequences 73  architectures

Clan: KIX_like (CL0589)

Summary

Kix domain of CBP (creb binding protein) and MED13/15 Add an annotation

This superfamily is characterised by structures with three helices in a partly opened bundle bundle. There are both creb-binding proteins and activator-binding proteins on mediator subunits, such as higher eukaryotic 13 and fungal 15.

This clan contains 2 families and the total number of domains in the clan is 1103. The clan was built by P Coggill.

Members

This clan contains the following 2 member families:

KIX KIX_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
KIX_2 (PF16987) 653 (59.2%) View
KIX (PF02172) 450 (40.8%) View
Total: 2 Total: 1103 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
KIX LMSTEN
pKID
LMSTEN KIX

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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