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621  structures 21619  species 6  interactions 47743  sequences 35  architectures

Clan: LDH_C (CL0341)

Summary

LDH C-terminal domain-like superfamily Add an annotation

This superfamily includes the C-terminal domain of lactate/malate dehydrogenase as well as the C-terminal domain of the glycosyl hydrolase 4 family.

This clan contains 2 families and the total number of domains in the clan is 47743. The clan was built by A Bateman.

Members

This clan contains the following 2 member families:

Glyco_hydro_4C Ldh_1_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ldh_1_C (PF02866) 34208 (71.7%) View
Glyco_hydro_4C (PF11975) 13535 (28.3%) View
Total: 2 Total: 47743 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 6 interactions for this clan. More...

Interacting families
A B
Glyco_hydro_4 Glyco_hydro_4C
Glyco_hydro_4C Glyco_hydro_4
Glyco_hydro_4C
Ldh_1_C Ldh_1_C
Ldh_1_N
Ldh_1_N Ldh_1_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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