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798  structures 7668  species 6  interactions 17217  sequences 82  architectures

Clan: LDH_C (CL0341)


LDH C-terminal domain-like superfamily Add an annotation

This superfamily includes the C-terminal domain of lactate/malate dehydrogenase as well as the C-terminal domain of the glycosyl hydrolase 4 family.

This clan contains 2 families and the total number of domains in the clan is 17217. The clan was built by A Bateman.


This clan contains the following 2 member families:

Glyco_hydro_4C Ldh_1_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ldh_1_C (PF02866) 13715 (79.7%) View
Glyco_hydro_4C (PF11975) 3502 (20.3%) View
Total: 2 Total: 17217 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 6 interactions for this clan. More...

Interacting families
Glyco_hydro_4 Glyco_hydro_4C
Glyco_hydro_4C Glyco_hydro_4
Ldh_1_C Ldh_1_C
Ldh_1_N Ldh_1_C


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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