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418  structures 9389  species 30  interactions 87233  sequences 966  architectures

Clan: Leu-IlvD (CL0364)


LeuD/IlvD-like Add an annotation

Superfamily includes LeuD-like, IlvD/EDD C-terminal domain-like, and AF0055-like families.

This clan contains 10 families and the total number of domains in the clan is 87233. The clan was built by A Bateman.


This clan contains the following 10 member families:

Aconitase_2_N Aconitase_C CPSase_sm_chain Cyclase DUF126 DUF2172 PA PEP-utilizers Peptidase_S66C RraA-like

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Aconitase_C (PF00694) 19224 (22.0%) View
PEP-utilizers (PF00391) 18811 (21.6%) View
PA (PF02225) 15168 (17.4%) View
CPSase_sm_chain (PF00988) 9172 (10.5%) View
Cyclase (PF04199) 8590 (9.8%) View
RraA-like (PF03737) 8242 (9.4%) View
Peptidase_S66C (PF17676) 4858 (5.6%) View
Aconitase_2_N (PF06434) 1937 (2.2%) View
DUF126 (PF01989) 853 (1.0%) View
DUF2172 (PF09940) 378 (0.4%) View
Total: 10 Total: 87233 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...




For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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