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24  structures 658  species 0  interactions 1144  sequences 11  architectures

Clan: Metallothionein (CL0461)

Summary

Metal-bound fold, usually iron, metallothionein superfamily Add an annotation

This superfamily contains related families of metallothioneins, prokaryotes and eukaryotes.

This clan contains 6 families and the total number of domains in the clan is 1144. The clan was built by P Coggill.

Members

This clan contains the following 6 member families:

Metallothi_Euk2 Metallothio Metallothio_6 Metallothio_Euk Metallothio_Pro Yeast_MT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Metallothio (PF00131) 610 (53.3%) View
Metallothio_Pro (PF02069) 416 (36.4%) View
Metallothio_Euk (PF12749) 58 (5.1%) View
Metallothio_6 (PF05522) 30 (2.6%) View
Metallothi_Euk2 (PF12809) 19 (1.7%) View
Yeast_MT (PF11403) 11 (1.0%) View
Total: 6 Total: 1144 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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