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736  structures 5432  species 39  interactions 58469  sequences 948  architectures

Clan: NTP_transf (CL0260)


Nucleotidyltransferase superfamily Add an annotation

This clan contains a diverse set of nucleotidyltransferase enzymes.

This clan contains 26 families and the total number of domains in the clan is 58469. The clan was built by A Bateman.


This clan contains the following 26 member families:

AbiEii Adenyl_cycl_N Adenyl_transf Aminoglyc_resit DNA_pol3_alpha DNA_pol_B_palm DUF2204 DUF294 DZF GlnE GrpB LicD MdcG Mmp37 Nrap Nrap_D4 NTP_transf_2 NTP_transf_5 NTP_transf_6 NTP_transf_7 NTP_transf_8 Nuc-transf PolyA_pol Pox_polyA_pol RelA_SpoT RsfS

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
NTP_transf_2 (PF01909) 11285 (19.3%) View
RelA_SpoT (PF04607) 7644 (13.1%) View
DNA_pol3_alpha (PF07733) 7316 (12.5%) View
PolyA_pol (PF01743) 6553 (11.2%) View
RsfS (PF02410) 4471 (7.6%) View
GlnE (PF03710) 3783 (6.5%) View
AbiEii (PF08843) 3028 (5.2%) View
LicD (PF04991) 2046 (3.5%) View
DUF294 (PF03445) 1577 (2.7%) View
GrpB (PF04229) 1404 (2.4%) View
DNA_pol_B_palm (PF14792) 1374 (2.3%) View
NTP_transf_5 (PF14907) 1106 (1.9%) View
Mmp37 (PF09139) 930 (1.6%) View
DZF (PF07528) 912 (1.6%) View
Pfam family Num. domains Alignment
Nuc-transf (PF10127) 882 (1.5%) View
Nrap_D4 (PF17405) 795 (1.4%) View
Nrap (PF03813) 726 (1.2%) View
NTP_transf_7 (PF07984) 632 (1.1%) View
NTP_transf_6 (PF06042) 540 (0.9%) View
Adenyl_transf (PF04439) 410 (0.7%) View
Adenyl_cycl_N (PF12633) 294 (0.5%) View
MdcG (PF10620) 242 (0.4%) View
NTP_transf_8 (PF12281) 213 (0.4%) View
DUF2204 (PF09970) 177 (0.3%) View
Aminoglyc_resit (PF10706) 117 (0.2%) View
Pox_polyA_pol (PF03296) 12 (0.0%) View
Total: 26 Total: 58469 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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