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60  structures 2328  species 5  interactions 6562  sequences 845  architectures

Clan: PA14 (CL0301)

Summary

PA14 superfamily Add an annotation

This clan includes the PA14 domain and related families.

This clan contains 2 families and the total number of domains in the clan is 6562. The clan was built by A Bateman.

Literature references

  1. Rigden DJ, Mello LV, Galperin MY; , Trends Biochem Sci. 2004;29:335-339.: The PA14 domain, a conserved all-beta domain in bacterial toxins, enzymes, adhesins and signaling molecules. PUBMED:15236739 EPMC:15236739

Members

This clan contains the following 2 member families:

GLEYA PA14

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PA14 (PF07691) 5878 (89.6%) View
GLEYA (PF10528) 684 (10.4%) View
Total: 2 Total: 6562 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 5 interactions for this clan. More...

Interacting families
A B
Glyco_hydro_3 PA14
Glyco_hydro_3_C PA14
PA14 Binary_toxB
Glyco_hydro_3
Glyco_hydro_31

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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