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615  structures 4966  species 4  interactions 46701  sequences 901  architectures

Clan: PDZ-like (CL0466)


PDZ domain-like peptide-binding superfamily Add an annotation

This superfamily comprises families of PDZ domains, which are peptide binding sites.

This clan contains 5 families and the total number of domains in the clan is 46701. The clan was built by P Coggill.


This clan contains the following 5 member families:

GRASP55_65 PDZ PDZ_1 PDZ_2 Tricorn_PDZ

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PDZ (PF00595) 26099 (55.9%) View
PDZ_2 (PF13180) 19233 (41.2%) View
GRASP55_65 (PF04495) 638 (1.4%) View
PDZ_1 (PF12812) 382 (0.8%) View
Tricorn_PDZ (PF14685) 349 (0.7%) View
Total: 5 Total: 46701 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 4 interactions for this clan. More...

Interacting families


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...