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1163  structures 4910  species 11  interactions 18915  sequences 431  architectures

Clan: PUP (CL0408)

Summary

Purine and uridine phosphorylase superfamily Add an annotation

superfamily contains a number of purine nucleoside phosphorylase, uridine nucleoside phosphorylase, and various nucleosidase families of proteins.

This clan contains 6 families and the total number of domains in the clan is 18915. The clan was built by A Bateman.

Members

This clan contains the following 6 member families:

AMNp_N NUP PAC2 PNP_UDP_1 POC1 tRNA_deacylase

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PNP_UDP_1 (PF01048) 15391 (81.4%) View
PAC2 (PF09754) 1995 (10.5%) View
AMNp_N (PF10423) 678 (3.6%) View
NUP (PF06516) 475 (2.5%) View
tRNA_deacylase (PF04414) 335 (1.8%) View
POC1 (PF10450) 41 (0.2%) View
Total: 6 Total: 18915 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 11 interactions for this clan. More...

Interacting families
A B
AMNp_N AMNp_N
PNP_UDP_1
MHC_I PNP_UDP_1
PAC2 PAC2
PNP_UDP_1 AMNp_N
PNP_UDP_1
POC1 PAC2
Proteasome POC1
Proteasome_A_N PAC2
POC1
tRNA_deacylase tRNA_deacylase

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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