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217  structures 4399  species 5  interactions 45644  sequences 1681  architectures

Clan: Pec_lyase-like (CL0268)


Pectate lyase-like beta helix Add an annotation

This superfamily all contain a right handed beta helix similar to that first found in pectate lyase [1].

This clan contains 22 families and the total number of domains in the clan is 45644. The clan was built by A Bateman.

Literature references

  1. Jenkins J, Mayans O, Pickersgill R; , J Struct Biol. 1998;122:236-246.: Structure and evolution of parallel beta-helix proteins. PUBMED:9724625 EPMC:9724625


This clan contains the following 22 member families:

Adeno_E1B_55K Autotrns_rpt Beta_helix Chlam_PMP Chondroitinas_B Disaggr_assoc DUF1565 DUF3737 Fil_haemagg Fil_haemagg_2 Glyco_hydro_28 Glyco_hydro_49 Glyco_hydro_80 Glyco_hydro_92 Haemagg_act NosD Pec_lyase_C Pectate_lyase Pectate_lyase_3 Pectinesterase Pertactin PhageP22-tail

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Autotrns_rpt (PF12951) 7020 (15.4%) View
Fil_haemagg (PF05594) 6916 (15.2%) View
Beta_helix (PF13229) 5365 (11.8%) View
Fil_haemagg_2 (PF13332) 4185 (9.2%) View
Glyco_hydro_28 (PF00295) 3587 (7.9%) View
Pectinesterase (PF01095) 2674 (5.9%) View
Pertactin (PF03212) 2661 (5.8%) View
Pectate_lyase_3 (PF12708) 2481 (5.4%) View
Glyco_hydro_92 (PF07971) 2270 (5.0%) View
Chlam_PMP (PF02415) 2166 (4.7%) View
Haemagg_act (PF05860) 2008 (4.4%) View
Pec_lyase_C (PF00544) 1509 (3.3%) View
Pfam family Num. domains Alignment
NosD (PF05048) 1281 (2.8%) View
Pectate_lyase (PF03211) 678 (1.5%) View
DUF1565 (PF07602) 240 (0.5%) View
DUF3737 (PF12541) 223 (0.5%) View
Adeno_E1B_55K (PF01696) 139 (0.3%) View
Chondroitinas_B (PF14592) 114 (0.2%) View
PhageP22-tail (PF09251) 48 (0.1%) View
Disaggr_assoc (PF08480) 34 (0.1%) View
Glyco_hydro_49 (PF03718) 30 (0.1%) View
Glyco_hydro_80 (PF13647) 15 (0.0%) View
Total: 22 Total: 45644 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 5 interactions for this clan. More...

Interacting families
Pectinesterase Pectinesterase
PhageP22-tail PhageP22-tail
Glyco_hydro_28 fn3
Pertactin Pertactin


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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