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57  structures 473  species 3  interactions 9700  sequences 42  architectures

Clan: Prolamin (CL0482)


Di-sulfide bond pairrings Add an annotation

This superfamily is characterised by families with only slightly differing disulfide-bonding patterning.

This clan contains 5 families and the total number of domains in the clan is 9700. The clan was built by P Coggill.

Literature references

  1. Zhang D;, Cell Cycle. 2009;8:3428-3430.: Homology between DUF784, DUF1278 domains and the plant prolamin superfamily typifies evolutionary changes of disulfide bonding patterns. PUBMED:19806031 EPMC:19806031


This clan contains the following 5 member families:

Gliadin Hydrophob_seed LTP_2 Prolamin_like Tryp_alpha_amyl

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Tryp_alpha_amyl (PF00234) 3260 (33.6%) View
LTP_2 (PF14368) 2454 (25.3%) View
Gliadin (PF13016) 2216 (22.8%) View
Hydrophob_seed (PF14547) 1054 (10.9%) View
Prolamin_like (PF05617) 716 (7.4%) View
Total: 5 Total: 9700 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
Alpha-amylase Tryp_alpha_amyl
SBP_bac_1 Tryp_alpha_amyl
Tryp_alpha_amyl Tryp_alpha_amyl


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...