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2644  structures 11525  species 0  interactions 481615  sequences 10804  architectures

Clan: RNase_H (CL0219)

Summary

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
rve (PF00665) 45153 (9.4%) View
RNase_T (PF00929) 37364 (7.8%) View
RT_RNaseH_2 (PF17919) 26244 (5.4%) View
RVT_3 (PF13456) 22150 (4.6%) View
DNA_pol_A_exo1 (PF01612) 21114 (4.4%) View
DDE_Tnp_1 (PF01609) 20414 (4.2%) View
DDE_3 (PF13358) 19072 (4.0%) View
DDE_Tnp_4 (PF13359) 18886 (3.9%) View
RNase_H (PF00075) 18650 (3.9%) View
MULE (PF10551) 18636 (3.9%) View
RT_RNaseH (PF17917) 16150 (3.4%) View
Piwi (PF02171) 14038 (2.9%) View
DDE_1 (PF03184) 11828 (2.5%) View
RNase_HII (PF01351) 10805 (2.2%) View
DNA_pol_B_exo1 (PF03104) 10753 (2.2%) View
rve_3 (PF13683) 10300 (2.1%) View
Ribosomal_S30AE (PF02482) 9683 (2.0%) View
DDE_Tnp_1_7 (PF13843) 9660 (2.0%) View
Transposase_mut (PF00872) 9095 (1.9%) View
OrfB_IS605 (PF01385) 8757 (1.8%) View
rve_2 (PF13333) 8690 (1.8%) View
CAF1 (PF04857) 8490 (1.8%) View
UvrC_RNaseH_dom (PF08459) 8039 (1.7%) View
DDE_Tnp_ISL3 (PF01610) 7299 (1.5%) View
RuvC (PF02075) 6948 (1.4%) View
DDE_Tnp_IS66 (PF03050) 6712 (1.4%) View
Plavaka (PF18759) 6577 (1.4%) View
KDZ (PF18758) 5815 (1.2%) View
DDE_Tnp_1_6 (PF13751) 4397 (0.9%) View
Methyltransf_1N (PF02870) 4246 (0.9%) View
DDE_Tnp_IS1595 (PF12762) 4216 (0.9%) View
DDE_5 (PF13546) 3926 (0.8%) View
DDE_Tnp_IS240 (PF13610) 3661 (0.8%) View
Transposase_21 (PF02992) 3632 (0.8%) View
Plant_tran (PF04827) 3244 (0.7%) View
DDE_Tnp_1_2 (PF13586) 3210 (0.7%) View
continued
Pfam family Num. domains Alignment
DDE_Tnp_1_4 (PF13701) 3174 (0.7%) View
Terminase_6C (PF17289) 3087 (0.6%) View
Endonuclease_5 (PF04493) 3078 (0.6%) View
RNase_H_2 (PF13482) 2708 (0.6%) View
TerL_nuclease (PF20441) 2621 (0.5%) View
DDE_Tnp_Tn3 (PF01526) 2478 (0.5%) View
Transposase_1 (PF01359) 1985 (0.4%) View
DDE_Tnp_1_3 (PF13612) 1735 (0.4%) View
DDE_Tnp_1_5 (PF13737) 1443 (0.3%) View
DNA_pol_B_exo2 (PF10108) 1335 (0.3%) View
Rv2179c-like (PF16473) 1216 (0.3%) View
DDE_Tnp_IS1 (PF03400) 1088 (0.2%) View
DDE_Tnp_ISAZ013 (PF07592) 872 (0.2%) View
Terminase_3C (PF17288) 827 (0.2%) View
NurA (PF09376) 767 (0.2%) View
DUF3892 (PF13031) 721 (0.1%) View
UPF0236 (PF06782) 692 (0.1%) View
RNaseH_like (PF04308) 626 (0.1%) View
Maelstrom (PF13017) 553 (0.1%) View
DUF2779 (PF11074) 498 (0.1%) View
Ydc2-catalyt (PF09159) 481 (0.1%) View
Dimer_Tnp_Tn5 (PF02281) 358 (0.1%) View
DUF99 (PF01949) 335 (0.1%) View
DNA_pol_P_Exo (PF18049) 271 (0.1%) View
DDE_Tnp_2 (PF04693) 233 (0.0%) View
DDE_2 (PF02914) 208 (0.0%) View
DUF1258 (PF06869) 112 (0.0%) View
Pox_A22 (PF04848) 93 (0.0%) View
DUF3882 (PF07066) 73 (0.0%) View
RuvC_1 (PF18516) 36 (0.0%) View
Taq-exonuc (PF09281) 33 (0.0%) View
Arena_ncap_C (PF17290) 15 (0.0%) View
DUF4152 (PF13680) 5 (0.0%) View
MGMT_N (PF09153) 4 (0.0%) View
Total: 70 Total: 481615
No alignment ℹ
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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