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1593  structures 9666  species 52  interactions 33052  sequences 229  architectures

Clan: S11_L18p (CL0267)


Ribosomal protein S11/L18p superfamily Add an annotation

This superfamily includes two ribosomal proteins S11 and L18p as well as a domain from eukaryotic peptide chain release factor. This superfamily is likely to share an RNA-binding function.

This clan contains 17 families and the total number of domains in the clan is 33052. The clan was built by A Bateman.

Literature references

  1. Woestenenk EA, Gongadze GM, Shcherbakov DV, Rak AV, Garber MB, Hard T, Berglund H; , Biochem J. 2002;363:553-561.: The solution structure of ribosomal protein L18 from Thermus thermophilus reveals a conserved RNA-binding fold. PUBMED:11964156 EPMC:11964156


This clan contains the following 17 member families:

acVLRF1 baeRF_family10 baeRF_family11 baeRF_family12 baeRF_family2 baeRF_family3 baeRF_family5 baeRF_family6 baeRF_family7 baeRF_family8 bVLRF1 eRF1_1 eRF1_2 Host_attach Ribosomal_L18p Ribosomal_L5e Ribosomal_S11

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ribosomal_S11 (PF00411) 10989 (33.2%) View
Ribosomal_L18p (PF00861) 9002 (27.2%) View
eRF1_2 (PF03464) 3206 (9.7%) View
eRF1_1 (PF03463) 3198 (9.7%) View
Ribosomal_L5e (PF17144) 2252 (6.8%) View
bVLRF1 (PF18826) 1063 (3.2%) View
Host_attach (PF10116) 716 (2.2%) View
baeRF_family2 (PF18844) 538 (1.6%) View
baeRF_family12 (PF18856) 528 (1.6%) View
baeRF_family3 (PF18845) 472 (1.4%) View
acVLRF1 (PF18859) 384 (1.2%) View
baeRF_family10 (PF18854) 183 (0.6%) View
baeRF_family6 (PF18848) 178 (0.5%) View
baeRF_family5 (PF18846) 115 (0.3%) View
baeRF_family7 (PF18849) 111 (0.3%) View
baeRF_family11 (PF18855) 70 (0.2%) View
baeRF_family8 (PF18851) 47 (0.1%) View
Total: 17 Total: 33052 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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