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263  structures 8974  species 15  interactions 24606  sequences 229  architectures

Clan: SufE_NifU (CL0233)


SufE/NifU superfamily Add an annotation

This clan includes iron sulfur cluster assembly proteins.

This clan contains 4 families and the total number of domains in the clan is 24606. The clan was built by A Bateman.


This clan contains the following 4 member families:

CO_deh_flav_C Lip_prot_lig_C NifU_N SufE

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
CO_deh_flav_C (PF03450) 10152 (41.3%) View
NifU_N (PF01592) 8794 (35.7%) View
SufE (PF02657) 3884 (15.8%) View
Lip_prot_lig_C (PF10437) 1776 (7.2%) View
Total: 4 Total: 24606 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 15 interactions for this clan. More...

Interacting families
Ald_Xan_dh_C2 CO_deh_flav_C
Aminotran_5 NifU_N
BPL_LplA_LipB Lip_prot_lig_C
CO_deh_flav_C Ald_Xan_dh_C2
FAD_binding_5 CO_deh_flav_C
Fer2 CO_deh_flav_C
Fer2_2 CO_deh_flav_C
Lip_prot_lig_C BPL_LplA_LipB
NifU_N NifU_N
SufE SufE


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...